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MY pBAT Stats From June to March 8 months
Hi All, Just thought I would give an update on my pBAT (Testosterone propianate BAT) for the last 8 months. I do T propianate injections every other day while on High T for 2 weeks then slam the door with Darolutamide for 2 weeks and then one week to clear the Daro. Rinse and repeat. I also take intermittent
Hi All, Just thought I would give an update on my pBAT (Testosterone propianate BAT) for the last 8 months. I do T propianate injections every other day while on High T for 2 weeks then slam the door with Darolutamide for 2 weeks and then one week to clear the Daro. Rinse and repeat. I also take intermittent
KocoPr
in
Fight Prostate Cancer
6 months ago
Revised Plot of PSA vs Testosterone: Estrogen vs Lupron ADT
Ugh...I made a BIG mistake on the previous posting! I just realized that Dr. Morgentaler had listed the Testosterone level in unusual units (
ng/mL
), not the usual units of (
ng/dL)
. So, my X-axis was off by a factor of 10. Here is the revised plot. The exciting discovery is that the
Ugh...I made a BIG mistake on the previous posting! I just realized that Dr. Morgentaler had listed the Testosterone level in unusual units (
ng/mL
), not the usual units of (
ng/dL)
. So, my X-axis was off by a factor of 10. Here is the revised plot. The exciting discovery is that the
janebob99
in
Advanced Prostate Cancer
6 months ago
Morgentaler Saturation Model: PSA vs Testosterone - Estrogen Patch vs Lupron ADT
This is a plot of % reduction in PSA from a Maximum Value versus Testosterone, for two different datasets: Estrogen Patch and Lupron ADT. Both curves (red and green lines) show a linear response starting from (0,0), up to about 200-250 ng/dL. Then, the lines curve over to a lower slope (especially
This is a plot of % reduction in PSA from a Maximum Value versus Testosterone, for two different datasets: Estrogen Patch and Lupron ADT. Both curves (red and green lines) show a linear response starting from (0,0), up to about 200-250 ng/dL. Then, the lines curve over to a lower slope (especially
janebob99
in
Advanced Prostate Cancer
6 months ago
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PSA vs Testosterone at high T levels - Linear Model
This is a plot of PSA versus Testosterone in men with prostate cancer. The blue points are taken from a YouTube video lecture by A. Morgentaler (2020). https://www.youtube.com/watch?v=wafNZV-Hkqk The green point is from Safraidi (2022): https://oamjms.eu/index.php/mjms/article/view/9388 Note the
This is a plot of PSA versus Testosterone in men with prostate cancer. The blue points are taken from a YouTube video lecture by A. Morgentaler (2020). https://www.youtube.com/watch?v=wafNZV-Hkqk The green point is from Safraidi (2022): https://oamjms.eu/index.php/mjms/article/view/9388 Note the
janebob99
in
Advanced Prostate Cancer
6 months ago
PSMA Scan to be scheduled - thank you Tall Allen
I want to thank Tall Allen for his suggestion that I see an oncologist. I had a RP followed by radiation in 2013. My PSA was undetectable until 2021, when it started to rise. This week I saw a radiation oncologist (whom I found through a friend) to ask him a lot of questions and to get his advice.
I want to thank Tall Allen for his suggestion that I see an oncologist. I had a RP followed by radiation in 2013. My PSA was undetectable until 2021, when it started to rise. This week I saw a radiation oncologist (whom I found through a friend) to ask him a lot of questions and to get his advice.
Geno2853
in
Advanced Prostate Cancer
6 months ago
ADT response and questions for MO
Hi, I am newish to this forum, still on a steep learning curve but I want to thank you for your contributions and discussions. This is my first time posting. My partner is 60 yrs old, as I understand it he had low PSA 3 yrs ago, not tested until Nov 2023, PSA50, stage 4, 1 met in 'sit' bone. Started
Hi, I am newish to this forum, still on a steep learning curve but I want to thank you for your contributions and discussions. This is my first time posting. My partner is 60 yrs old, as I understand it he had low PSA 3 yrs ago, not tested until Nov 2023, PSA50, stage 4, 1 met in 'sit' bone. Started
Lovecherries
in
Advanced Prostate Cancer
6 months ago
One questions doctors never seem to be able to answer is at what PSA level do you start to experience pain or physical problems?
One questions doctors never seem to be able to answer is at what PSA level do you start to experience pain or physical problems? If you have had surgery, Salvage Radiation, ADT, SRBT and then stopped ADT with a continuing rise in you PSA when did you start to have pain or physical problems?
One questions doctors never seem to be able to answer is at what PSA level do you start to experience pain or physical problems? If you have had surgery, Salvage Radiation, ADT, SRBT and then stopped ADT with a continuing rise in you PSA when did you start to have pain or physical problems?
Exrunner
in
Advanced Prostate Cancer
6 months ago
Enzalutamide vs Lupron Survival
This shows the main results of the EMBARK trial, comparing Metatasis Free Survival and PSA Recurrence Free Survival for three groups: Enzalutamide only, Lupron only, or combined Enzalutamide + Lupron. The best survivals were for the combination of Enzalutamide + Lupron. Enzalutamide is a 2nd generation
This shows the main results of the EMBARK trial, comparing Metatasis Free Survival and PSA Recurrence Free Survival for three groups: Enzalutamide only, Lupron only, or combined Enzalutamide + Lupron. The best survivals were for the combination of Enzalutamide + Lupron. Enzalutamide is a 2nd generation
janebob99
in
Prostate Cancer Network
6 months ago
Help to do BAT treatment for my dad. Located in Norway.
Hello everyone! Writing on behalf of my father who is 67 yo and has prostate cancer. We are based in Norway. Prostatectomy done in March -17. Treated with Bicalutamide and Zoladex injection until rise in PSA 18 months ago. Increasing PSA from 6-12 on chemotherapy through last summer. September he was
Hello everyone! Writing on behalf of my father who is 67 yo and has prostate cancer. We are based in Norway. Prostatectomy done in March -17. Treated with Bicalutamide and Zoladex injection until rise in PSA 18 months ago. Increasing PSA from 6-12 on chemotherapy through last summer. September he was
VonKantarellen
in
Advanced Prostate Cancer
6 months ago
În panica again
Hello, everybody! Wishing you a happy and bright spring! I need you expertise and oppinions again. My father is taking Xtandy for over 1.2 years and lately psa started to grow, I attached his psa situation since january 2022. I read about Xtandy here all the time. It never worked so good for him, I
Hello, everybody! Wishing you a happy and bright spring! I need you expertise and oppinions again. My father is taking Xtandy for over 1.2 years and lately psa started to grow, I attached his psa situation since january 2022. I read about Xtandy here all the time. It never worked so good for him, I
tuta1960
in
Advanced Prostate Cancer
6 months ago
Pluvicto Question
Just had third Pluvicto in fusion and Spect scan today and got results. Not sure what this means. If the findings are similar compared to the last scan why does this indicate"technically successful" therapy. Also PSA went down just slightly after infusion number two but went up a little from PSA after
Just had third Pluvicto in fusion and Spect scan today and got results. Not sure what this means. If the findings are similar compared to the last scan why does this indicate"technically successful" therapy. Also PSA went down just slightly after infusion number two but went up a little from PSA after
spencoid2
in
Advanced Prostate Cancer
6 months ago
life Insurance
I wanted to get opinions regarding my life insurance 800K which will be expiring in a couple of months. I have the option to roll it over to a universal policy but it’s going to cost me 2K a month. I’m still Homone sensitive. And been on ADT and Nubeqa (daroludimide) for the last couple of years. Had
I wanted to get opinions regarding my life insurance 800K which will be expiring in a couple of months. I have the option to roll it over to a universal policy but it’s going to cost me 2K a month. I’m still Homone sensitive. And been on ADT and Nubeqa (daroludimide) for the last couple of years. Had
JDKotter
in
Advanced Prostate Cancer
6 months ago
PSA now undetectable with 2 of 35 radiation treatments left.
PSA now undetectable with 2 of 35 radiation treatments left to complete. I will start Abiraterone next week, in addition to the Lupron I’m currently on. I’m celebrating today’s victory and wanted to share here. Of course, many days have been consumed with worry over the unknown. This group has been
PSA now undetectable with 2 of 35 radiation treatments left to complete. I will start Abiraterone next week, in addition to the Lupron I’m currently on. I’m celebrating today’s victory and wanted to share here. Of course, many days have been consumed with worry over the unknown. This group has been
Stereo1
in
Advanced Prostate Cancer
6 months ago
ISO a third MO opinion for my dad
Hi all! My dad was diagnosed with pca in 2021, prostate removal that summer. After radical - was told no treatment necessary and lo and behold January the following year psa went from .04 to 1.2 in 3 months. Put on adt and zytiga (not sure of spelling), scans show pelvic bed spots and 1 on s1, radiation
Hi all! My dad was diagnosed with pca in 2021, prostate removal that summer. After radical - was told no treatment necessary and lo and behold January the following year psa went from .04 to 1.2 in 3 months. Put on adt and zytiga (not sure of spelling), scans show pelvic bed spots and 1 on s1, radiation
Dsmejkal88
in
Advanced Prostate Cancer
6 months ago
PSA doubled in last 30 days after 4 months stable since Provenge. What's next?
Update: PSA remained roughly 1.7 to 1.8 for last 4 months after Provenge but yesterday's 30-day PSA test revealed a jump to 3.190 so something is growing quick. I have been off of all ADT since finishing fourth LU-177 injection five months ago and one SBRT treatment 4 months ago. After LU-177, PSA
Update: PSA remained roughly 1.7 to 1.8 for last 4 months after Provenge but yesterday's 30-day PSA test revealed a jump to 3.190 so something is growing quick. I have been off of all ADT since finishing fourth LU-177 injection five months ago and one SBRT treatment 4 months ago. After LU-177, PSA
SViking
in
Advanced Prostate Cancer
6 months ago
Clinical Trial PT 112 ?
I’m writing for my husband who is French (I’m English : we live in France ) He’s 65 and was diagnosed in March 2022 - already metastatic : PSA 36 (previous test 18months before was normal ) Mets in spine and pelvis also liver . Enantone 3 monthly injections and Zytiga to start with. PSA went down
I’m writing for my husband who is French (I’m English : we live in France ) He’s 65 and was diagnosed in March 2022 - already metastatic : PSA 36 (previous test 18months before was normal ) Mets in spine and pelvis also liver . Enantone 3 monthly injections and Zytiga to start with. PSA went down
Enilorac63
in
Advanced Prostate Cancer
6 months ago
Is it PSA recurrence or not...
My friend had a radical prostatectomy a year ago. Since then his monthly PSA results were stable, at 0.006 3 months ago his PSA went from 0.006 to 0.012, then the next month to 0.029. His MO wanted to see the third month's results in order to consider salvage radiation therapy. Luckily, third month's
My friend had a radical prostatectomy a year ago. Since then his monthly PSA results were stable, at 0.006 3 months ago his PSA went from 0.006 to 0.012, then the next month to 0.029. His MO wanted to see the third month's results in order to consider salvage radiation therapy. Luckily, third month's
traveller64
in
Advanced Prostate Cancer
6 months ago
PSA vs Testosterone Nadir for CRPC and Non-CRPC
This plot from Safriadi (2022) compares the mean values of PSA nadir versus Testosterone Nadir comparing Non-Castrate Resistant PC (Non-CRPC) to Castrate-Resistant PC (CRPC) men. For Non-CRPC men, the range of T-nadir was 2.5-49 ng/dL (mean = 21) and range for PSA nadir was 0.02-9 ng/mL (mean=2). For
This plot from Safriadi (2022) compares the mean values of PSA nadir versus Testosterone Nadir comparing Non-Castrate Resistant PC (Non-CRPC) to Castrate-Resistant PC (CRPC) men. For Non-CRPC men, the range of T-nadir was 2.5-49 ng/dL (mean = 21) and range for PSA nadir was 0.02-9 ng/mL (mean=2). For
janebob99
in
Advanced Prostate Cancer
6 months ago
Mortality Probability after first PSA rise vs non-castrate testosterone levels (low vs Normal)
Here's a plot from Atkins (2018) that shows the Percent risk of Prostate Cancer-specific Mortality versus time following a first PSA failure, for two different non-castrate testosterone levels (Low-T and Normal-T). The low testosterone levels are: median = 162, range = 120-236 ng/dL. Normal T is 400
Here's a plot from Atkins (2018) that shows the Percent risk of Prostate Cancer-specific Mortality versus time following a first PSA failure, for two different non-castrate testosterone levels (Low-T and Normal-T). The low testosterone levels are: median = 162, range = 120-236 ng/dL. Normal T is 400
janebob99
in
Advanced Prostate Cancer
6 months ago
PSA Score Doubling / Lab Error?
Hey folks I was diagnosed back in 2017 with 3+3, later upgraded to 3+4, but with less then 5% of G4. Epstein reviewed and said he would go against Johns Hopkins policy to automatically treat ANY amount of G4 and stick with AS, at least in my situation. Before and since my diagnosis, my PSA score has
Hey folks I was diagnosed back in 2017 with 3+3, later upgraded to 3+4, but with less then 5% of G4. Epstein reviewed and said he would go against Johns Hopkins policy to automatically treat ANY amount of G4 and stick with AS, at least in my situation. Before and since my diagnosis, my PSA score has
PTvsPC
in
Prostate Cancer Network
6 months ago
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