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10-year update still shows no benefit to ART vs early SRT
ART
= adjuvant radiation therapy, within 6 months after radical prostatectomy (RP)
early SRT
= salvage radiation therapy, after PSA ≥ 0.1ng/ml or 3 consecutive rises. Median was 0.2 ng/ml. Median 1 ½ years after RP. Patients risked nothing by waiting, and gained urinary and fecal continence
ART
= adjuvant radiation therapy, within 6 months after radical prostatectomy (RP)
early SRT
= salvage radiation therapy, after PSA ≥ 0.1ng/ml or 3 consecutive rises. Median was 0.2 ng/ml. Median 1 ½ years after RP. Patients risked nothing by waiting, and gained urinary and fecal continence
Tall_Allen
in
Advanced Prostate Cancer
2 hours ago
Explain my PSMA PET SCAN Please..
PSMA PET/CT from the skull base to midthigh demonstrates: 1. Worsening of skeletal metastases. 2. Multiple sclerotic lesions without activity represent treated metastatic disease. 3. Status post orchiectomy. 4. No abnormal uptake of tracer within the prostatic bed. EXAM: PET CT PSMA CLINICAL
PSMA PET/CT from the skull base to midthigh demonstrates: 1. Worsening of skeletal metastases. 2. Multiple sclerotic lesions without activity represent treated metastatic disease. 3. Status post orchiectomy. 4. No abnormal uptake of tracer within the prostatic bed. EXAM: PET CT PSMA CLINICAL
God_Loves_Me
in
Advanced Prostate Cancer
7 hours ago
Docetaxel Failing
Greetings from Inverness in the beautiful Highlands of Scotland! I would like to share my journey with you and hopefully get some advice on future treatments. In December 2022 following diagnoses of advanced prostate cancer with multiple bone metastasis I started zytiga + prednisone and 6 monthly triptorelin
Greetings from Inverness in the beautiful Highlands of Scotland! I would like to share my journey with you and hopefully get some advice on future treatments. In December 2022 following diagnoses of advanced prostate cancer with multiple bone metastasis I started zytiga + prednisone and 6 monthly triptorelin
Fisherman2
in
Advanced Prostate Cancer
7 hours ago
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BILLY NEEDS HELP
OK troops, after 26 years of surviving post prostectomy, with a Gleason 4/3, 4/4, some 41 rounds of intermittent hormone therapy using lupron, casadex, advodart, I had a break thru last November as my psa went back up mid on cycle. After having my radiation oncologist ignore the realities of this, I
OK troops, after 26 years of surviving post prostectomy, with a Gleason 4/3, 4/4, some 41 rounds of intermittent hormone therapy using lupron, casadex, advodart, I had a break thru last November as my psa went back up mid on cycle. After having my radiation oncologist ignore the realities of this, I
billyboy3
in
Advanced Prostate Cancer
8 hours ago
Moving on to Provenge/Sipuleucel-t
We met with my husband's onc yesterday to discuss the next move since the 3 years of Abiraraterone/prednisone has run its course. His psa numbers are now around 2.0 (up from a low of .04) and psma scan indicates that bone met volume is quite low. A recent lab biopsy didn't reveal much... The good doc
We met with my husband's onc yesterday to discuss the next move since the 3 years of Abiraraterone/prednisone has run its course. His psa numbers are now around 2.0 (up from a low of .04) and psma scan indicates that bone met volume is quite low. A recent lab biopsy didn't reveal much... The good doc
Lavender22
in
Advanced Prostate Cancer
13 hours ago
Pancreas problems after RT for prostate
I was diagnosed with prostate cancer two years ago. Received radiotherapy and hormone therapy. My PSA levels have dropped and progress seems OK. I have also had M.E. and fibromyalgia for over 25 years and, as part of that, IBS. Since starting the hormone therapy and radiotherapy I became more and more
I was diagnosed with prostate cancer two years ago. Received radiotherapy and hormone therapy. My PSA levels have dropped and progress seems OK. I have also had M.E. and fibromyalgia for over 25 years and, as part of that, IBS. Since starting the hormone therapy and radiotherapy I became more and more
Nomojo56
in
Pelvic Radiation Disease Association
16 hours ago
Wondering if anyone can relate to these symptoms
After an appointment with a dietician I was tested for suspected EPI and my level was very low - 53. I have been prescribed Creon 25000 and taking those for about 4 weeks.I have had M.E/CFS and fibromyalgia for over 25 years and two years ago was diagnosed with prostate cancer. I had radiotherapy and
After an appointment with a dietician I was tested for suspected EPI and my level was very low - 53. I have been prescribed Creon 25000 and taking those for about 4 weeks.I have had M.E/CFS and fibromyalgia for over 25 years and two years ago was diagnosed with prostate cancer. I had radiotherapy and
Nomojo56
in
Chronic Pancreatitis Support
18 hours ago
Appropriate Treatment
I was diagnosed with stage 4 prostate cancer PSA 29.1 which had metastatised to lymph nodes, ribs & spine after a few months on Abiraterone and Prednisone my PSA count dropped to 0.06 After 30 months my PSA started to rise at 10.2 my treatment was declared ineffective Lutetium 177 treatment was recommended
I was diagnosed with stage 4 prostate cancer PSA 29.1 which had metastatised to lymph nodes, ribs & spine after a few months on Abiraterone and Prednisone my PSA count dropped to 0.06 After 30 months my PSA started to rise at 10.2 my treatment was declared ineffective Lutetium 177 treatment was recommended
154Eleventh
in
Advanced Prostate Cancer
21 hours ago
10th year
Ten years ago I had my Gleason 9 prostate removed. PSA was .1 for a while. It crept up over .2, and I began taking lupron. The drug brought PSA back down to >.01 for a year or so. As the level started going up again, I received whole pelvis bed radiation, moving PSA to undetectable. After a year or so
Ten years ago I had my Gleason 9 prostate removed. PSA was .1 for a while. It crept up over .2, and I began taking lupron. The drug brought PSA back down to >.01 for a year or so. As the level started going up again, I received whole pelvis bed radiation, moving PSA to undetectable. After a year or so
Jvaughan0
in
Advanced Prostate Cancer
1 day ago
PSA Rising After PBRT
Underwent prostate bed radiation in 2022 with good results — about a year of PSA at .02 to .05 — past six months, .09 and now at .17 Will get a PSMA-PET, but am curious what’s next ??
Underwent prostate bed radiation in 2022 with good results — about a year of PSA at .02 to .05 — past six months, .09 and now at .17 Will get a PSMA-PET, but am curious what’s next ??
FLRichardson
in
Advanced Prostate Cancer
1 day ago
How do you know if radiation treatment worked?
I had 25 sessions of radiation to prostate and pelvic area as a precaution and 6 (2 months prior and 4 after radiation)months of Lupron. For 9 months post radiation PSA has been not been detectable and it has now risen to 0.04. T is in the normal range. All other blood works were normal. Meet with
I had 25 sessions of radiation to prostate and pelvic area as a precaution and 6 (2 months prior and 4 after radiation)months of Lupron. For 9 months post radiation PSA has been not been detectable and it has now risen to 0.04. T is in the normal range. All other blood works were normal. Meet with
Mgtd
in
Advanced Prostate Cancer
1 day ago
Good News! Pluvicto Update
Hey Guys, I just had my third round of Pluvicto this last Tuesday. I had bloodwork done last week. The news seems promising: On 28 January (after docetaxel, but before Pluvicto), my PSA was 36.2. After 2 rounds of Pluvicto on 8 April, my PSA had dropped to 14.5! So, I am remaining positive! I have
Hey Guys, I just had my third round of Pluvicto this last Tuesday. I had bloodwork done last week. The news seems promising: On 28 January (after docetaxel, but before Pluvicto), my PSA was 36.2. After 2 rounds of Pluvicto on 8 April, my PSA had dropped to 14.5! So, I am remaining positive! I have
MJCA
in
Advanced Prostate Cancer
1 day ago
225Ac-PSMA-I&T works well even after Pluvicto in small trial
It's small number of heavily-treated mCRPC patients, but 42% of those who already had Pluvicto had a PSA reduction of ≥50% from 225Ac-PSMA-I&T. Surprisingly, no Grade 3 Xerostomia. Phase III trials will likely follow. https://www.prnewswire.com/news-releases/fusion-pharmaceuticals-announces-presentation-of-interim-data-from-the-phase
It's small number of heavily-treated mCRPC patients, but 42% of those who already had Pluvicto had a PSA reduction of ≥50% from 225Ac-PSMA-I&T. Surprisingly, no Grade 3 Xerostomia. Phase III trials will likely follow. https://www.prnewswire.com/news-releases/fusion-pharmaceuticals-announces-presentation-of-interim-data-from-the-phase
Tall_Allen
in
Advanced Prostate Cancer
2 days ago
Improving Symptoms with Rising PSA
If prostate symptoms [i]
(less urinary frequency/less urgent urination/finally can sleep through night)
[/i] are improving, but PSA is increasing
(from 10 to15)
over last few years where at
10
MRI was negative, what does kind of pattern indicate or suggests?
If prostate symptoms [i]
(less urinary frequency/less urgent urination/finally can sleep through night)
[/i] are improving, but PSA is increasing
(from 10 to15)
over last few years where at
10
MRI was negative, what does kind of pattern indicate or suggests?
back2health
in
Advanced Prostate Cancer
2 days ago
Suddenly Urinary Leakage just walking around, then I have to push / strain to urinate, PSA rising, prostatectomy leakage resolved
Can anyone give me an idea what is going on? No UTI, No Urinary Infections I was tested Suddenly having Urinary Leakage just walking around, then I have to push / strain, to urinate. I had a Radical Prostatectomy in 03/2023 leakage resolved. I didn’t have radiation as much as I was waiting
Can anyone give me an idea what is going on? No UTI, No Urinary Infections I was tested Suddenly having Urinary Leakage just walking around, then I have to push / strain, to urinate. I had a Radical Prostatectomy in 03/2023 leakage resolved. I didn’t have radiation as much as I was waiting
Shorehousejam
in
Advanced Prostate Cancer
2 days ago
What are my options?
My bio is not necessarily up to date. I will update it but her is my most recent history and questions: I was getting Pluvicto treatments. Was supposed to get 6 but foe some reason that is not entirely clear at this point it was decided (i have three oncologist and do not know which one or combination
My bio is not necessarily up to date. I will update it but her is my most recent history and questions: I was getting Pluvicto treatments. Was supposed to get 6 but foe some reason that is not entirely clear at this point it was decided (i have three oncologist and do not know which one or combination
spencoid2
in
Advanced Prostate Cancer
2 days ago
Please help us decide on next treatment
Hi, my Dad was diagnosed back in 2021 with stage IV, Gleason 9, oligometastatic. He had 6 weeks of radiation at the time of diagnosis and has been for the past 2.5 years on Abiraterone, Prednisone and Lupron. As I mentioned in my prior post my Dad’s PSA started going up. He had a PSMA Pet scan and it
Hi, my Dad was diagnosed back in 2021 with stage IV, Gleason 9, oligometastatic. He had 6 weeks of radiation at the time of diagnosis and has been for the past 2.5 years on Abiraterone, Prednisone and Lupron. As I mentioned in my prior post my Dad’s PSA started going up. He had a PSMA Pet scan and it
Simonapo
in
Advanced Prostate Cancer
2 days ago
Need advice on clinical trial RO7656594
I have updated our profile, but in a nutshell we've gone through abiraterone, Xtandi, docetaxel, Pluvicto , cabazitaxel and carboplatin. My husband's most recent PSA on 4/12 was 79.52. His MO has put a hold on chemo our last 3 appointments due to pancytopenia. He's received 2 blood transfusions on his
I have updated our profile, but in a nutshell we've gone through abiraterone, Xtandi, docetaxel, Pluvicto , cabazitaxel and carboplatin. My husband's most recent PSA on 4/12 was 79.52. His MO has put a hold on chemo our last 3 appointments due to pancytopenia. He's received 2 blood transfusions on his
Yadifan
in
Advanced Prostate Cancer
2 days ago
Should I Add Docetaxel to Lupron and Zytiga?
I have been on Lupron and Abiraterone for most of my almost 12 years of treatment. Triplet therapy was not SOC when I was first dx'd. I am just wondering why, Docetaxel isn't routinely added to those of us who started on doublet therapy before we become resistant to the doublet therapy. My guess is that
I have been on Lupron and Abiraterone for most of my almost 12 years of treatment. Triplet therapy was not SOC when I was first dx'd. I am just wondering why, Docetaxel isn't routinely added to those of us who started on doublet therapy before we become resistant to the doublet therapy. My guess is that
jfoesq
in
Advanced Prostate Cancer
2 days ago
Just some good news
Just wanted to update you all on this in case anyone is thinking of surgery to fix something non-cancer related. My husband was looking into getting a hip replacement back in 2021 when he was diagnosed with PC. So the hip replacement was put on hold,. But the hip arthritis kept getting worse and he
Just wanted to update you all on this in case anyone is thinking of surgery to fix something non-cancer related. My husband was looking into getting a hip replacement back in 2021 when he was diagnosed with PC. So the hip replacement was put on hold,. But the hip arthritis kept getting worse and he
Bspouse
in
Advanced Prostate Cancer
3 days ago
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