Experiences with

Antagon

I had posted before: 64 current psa post op 0.39 PSMA showed left internal iliac node - likely more at this psa level I am not a candidate for rad rx due to previous pelvic radiation prior earlier in life Will have to start on ADT soon: - best meds? Doublet since low burden at this point - Tamoxafin

There we go, this is a great update! Pluvicto’s been the go-to standard, but new research like FC705 is totally blowing past it... FC705, a new radioligand therapy for metastatic castration-resistant prostate cancer (mCRPC), outperformed Pluvicto in phase 2 trials, achieving a 60.0% tumor response rate

Back in October, my PSMA PET scan revealed, besides a sub-centimeter lymph node lesion, a concerning lesion on my R frontal lobe of my skull, with uptake from the radioactive tracer. No other bone mets. My oncologists were all skeptical of this finding, but we agreed to do a brain MRI after I was finished

I’ve been on the ultra sensitive PSA tests since my Prostatectomy on 10/2019, mainly because that’s what is available and my high Decipher score and the recommendation to start Early Salvage if it starts to rise to 0.03 range and up; I will be getting another test to make sure it’s not lab noise since

Lupron first 2 shots reduced PSA from 300 to 40, but test after 3rd shot showed increase to 42.5. oncologist willing to start me on abiraterone (and prednisone) rather than wait another month for another test Good idea? Once I start abiraterone, is it forever? Jacques

UPDATE We received some good news! The Pet-PSM scan didn't show mets. So the starting point is looking less bleak now. Of course it remains very serious, since it is an aggressive tumor. This week we need to talk about how to move forward, choosing between radiation + injections or an operation.

I looked at this specifically for BAT. SPA might synergize with immunomodulators. As it often happens, I can't get the drugs that are powerful immunomodulators. So I look for natural substances. Usually orders of magnitude weaker but you do what you need to do. I'm going to try this out during SPA.

Hi- I try to enjoy my life and not worry too much about what the future may hold nor how long a future I may have- but today I felt the desire to inquire. I have been very fortunate in my response to doublet treatment therapy since my Dx almost 13 years ago (triplet therapy was not the SOC back then

The formatting doesn't come through. BAT in HSPC (HSPC Classification) Key Definitions 1. HSPC (Hormone-Sensitive Prostate Cancer): • Cancer responds to androgen deprivation therapy (ADT) with testosterone <50 ng/dL, evidenced by: • PSA suppression: • Post-radical prostatectomy (RP): Sustained

Husband's PSMA scan on 3/26/25 showed 1 new enlarged hypermetabolic lymph node on the right common illiac 3.6 cm x 3.6 cm with partial necrosis. SUV max 6.2. Increased metabolic activity of previous metabolic right external illiac lymph node which now measures maximum SUV of 6.9. Previously 2.9. The

Hi all - Stage 4, addressed with triplet therapy (Docetaxel, resumed Lupron, added darolutamide) starting in August 2022. PSA increasing since summer 2023, measured at 8 in January 2025. Bone & CT scans twice, first one picked up a single retroperitoneal lymph node > cm., second picked up three. My

Has anyone experienced numb chin from bone mets? I’ve been on Lupron, Abi, Lynparza, EBRT, Docy then docy/carboplatin combo 2019-Dec 2024. PSA is very high with multiple bone mets. In Jan my chin went numb along with lower front gums. Some sharp pain spikes but mostly annoyingly numb. Docs say

hi My dad did not take prednisone or Abiraterone for 12 days because of delayed prescription delivery. his PSA ⬇️dropped 0.006. can anyone comment on this?

Is it worth, do you think - giving up drinking and smoking and seeing what effect it has on your PSA ? - I was diagnosed stage 4 which had spread and gave both up - my PSA with treatment went from 50 ish to undetectable with - Xtandi and Gosalin - I live in the south of England in the UK

Hello. My husbands PSA has been rising since last August. From .50 to now 1.71. It has been rising slowly and MO kept saying to wait. We went for second opinion at Sloan Kettering and got the answer. Most recent PSMA PET scan in November showed no new mets and most of his original many metastasis

Prostatectomy in May 2020. A year later did salvage radiation after a PSA rise. Radiation seems to have done the job. PSA declining ever since and is holding at .006 since Aug 2024. So far so good. Now riddle me this… I started paying attention to Testo levels in 2019. Doc commented that TRT was

PSA at beginning of BAT last November was 12. After four months it hit 94 when we restarted Darolutimide. Then 12 days later it had dropped 38. Two weeks after that, it rose to 52. Oncologist suggested one of four options. Chemo, Pluvicto, Radium 223 or a new clinical trial involving Actinium

(Writing this for my dad since he has dyslexia) My 61 year old dad has one small metastases on his hip bone. He had his prostate removed, then 30 days of radiation, then Lupron, then added Zytiga when his PSA crept back up which he has been on for five years. He also got one round of SBRT for 5 days

This has bugged me for sometime so I thought I would ask the question. A PSA test result expressed to tenths like 0.1 is NOT an Ultra sensitive. Likewise a test expressed in thousands like 0.001 IS an Ultra sensitive test. How do you define one expressed to hundreds like 0.03? Is this a normal or an

75yo with RARP(Oct2019), Gleason 3+4, stage 2b with positive surgical margin. This was followed by SBRT 1 year later(Sep2020) because of rising PSA despite surgery. PSA continues to rise regardless. By 2023, PSA 0.17 (Apr2023), 0.24(Jul2023), 0.23(Aug2023), followed by a negative PSMA-PET(Oct 2023)