Experiences with

Antagon

Hello everyone, I am looking for your advice regarding the decision to proceed with prostate removal surgery. I was diagnosed with stage 4 P/ca in 2021 at the age of 70, and at that time, I had a metastasis on my hip bone. Surgery to remove the prostate was not an option then, so I began receiving

Have put myself on a vacation since I have some other issues which contribute to my increasing fatigue. Doing 6 months depot ADT for more than 4 years after radiation. PSA has been .01 every since. Was anxious to see my first PSA after 6 months. Still .01 and a little fatigue relief! Testosterone

My bio is up to date. I was undetectable but today it came back at this low number even though I am on Orgovyx and Erleada. I realize my pathology was horrible but being undetectable for 3.5 years post RP was excellent and then a slight tick up to 0.021 and 6 months later to 0.056 and then radiation

I have a friend who was diagnosed with Gleason 9 oligometastatic PC 9 months ago. His only treatment has been Ogorvyx and Xtandi. His PSA is undetectable. How did he escape RP or RT?

I need to decide. Urgency? Been on Lupron for 3 treatments now9months. Aware 5 - 10 year results similar. Where radiation much less side effects up front. long term +10 years rp has better recurrence free %. I would go radiation knowing I can do rp later if recurs, psa goes up. problem surgery

Underwent HDR BT October 2020 to treat 6(3+3), 7(3+4), and one unknown tumor missed by TRUS. Late 2024 PSA doubles from 1.51 ng/ml to 3.28 in 4 months, then to 5.08 four months later. Last Thur/Fri underwent PSMA PET and MRI at Roswell Park, Buffalo, NY. Major worry of metastasis is off the table

Another highly entertaining and informative podcast from [i]GU Cast. [/i] Hosts Prof. Declan Murphy and Dr Renu Eapen are joined by urologist and prostate cancer researcher Dr Steve Freedland - a world renowned urologist and researcher specialising in prostate cancer and BCR management. Dr Freedland

https://youtu.be/ItqlKCtlUKU?si=_RHc7eKkhEJ9Swin Did a Ventura Beach Therapy run and swapped out the Memorial Sign, the old was faded out and I had to add more names😢 https://visitventuraca.com/blog/haoles-rock-garden-in-ventura-tells-a-story-of-everything-right/ Did a Goodwill run also and got 3

I was initially diagnosed with prostate cancer un 2021 and treated with 23 radiation treatments and radioactive beads. In April of 2024 my Psa started to rise significantly and subsequent imaging showed I had stage 4 cancer that had spread to my lymph nodes. I was put on leuprolide inJune of 2024 and

OK....currently metachronous oligometastatic prostate cancer diagnosed this past Fall (2024). I had SBRT (MR-Linac)to the 2 positive iliac lymph nodes in early March and I am on 3 month shots of Erleada (started Mid January) and daily 2000mg of Abiraterone (Started Mid February). PSA at start of treatment

I was a Glason 8 with PSA 5.2 and had surgery to remove my prostate in 2018. My PSA has always been <0.02 since surgery and for past 2 years I’ve gotten my PSA tested annually. Last week I had my annual PSA test and my PSA was 0.03. Always get tested at same lab on same type of machine. Should

Completed 5 months of Taxotere 1/10/25 and stopped Orgovyx and Prednisone (iADT) on 1/23. PSA dropped from 15.5 to 0.07 on 2/20 but rose to 0.17 on 3/20. Don't like the doubling time. MO appt is 4/27 following 4/20 blood test. Assuming continued PSA rise I expect to be back on ADT and also getting a

I will be on on my third cycle next Monday. Bloodtest was very good, but PSA is still rising. From 4.29 from 2 months ago, now 5.50. Is it to early to expect if it's working? I'm very worried, even if I don't have any symptoms from my stage 4 mcrPC.

I've been on Orgovyx + Abi + 5mg Prednisone now for 3 months. I've had to hound my doc for an A1C and lipid profile, since these are known to affect them. My A1c has moved from the upper range of normal to well within diabetes. It was 5.5 and is now 6.7, ouch. That 5mg of prenisone is like eating

I am writing this to see if anyone has followed a similar path and can offer impressions of side effects for Erleada vs Abiriterone. Diagnosed stage 4 July 2022. Gleason 3+4. Started Abiraterone/Pred, Lupron, Zometa in September, so have been on it 2.5yrs. The lowest my PSA got was 0.14 in January

I thought that Rad-140/150 was safer than Ostarine or Ligandrol. The majority of the evidence now points me to Ostarine being the safest. Risk Comparison Table Parameter Ostarine Ligandrol RAD-140 Winner AR Agonism Partial Full Full Ostarine Prostate AR Activation Low Moderate High Ostarine Hepatotoxicity

My husband has been advised to have open heart surgery, for valve replacement and aortic root aneurysm graft. It is recommended to be done within the next three months. Though he has a growing aneurysm the surgeons were mostly concerned about the severe aortic valve regurgitation. The longer the valve

Hello all, While still being in the midst of a full diagnosis this forum had helped me a lot so far. My dad is as we speak getting his PET scan to see if and how far his PC had spread. It all started in Feb when he did a blood test after having peeing problems for quite some time. His PSA came back

recently started both Orgo and Xtandi for stage 4 Had previous HD brachy and EBRT of prostate which went well had cat and bone scans after that showed nothing except 4 bone mets 2 in spine and 2 in lower spin and hip These probably escaped prior to my above treatments as the treated area looks

​A recent Phase I clinical trial has revealed that FOR46, an experimental antibody-drug conjugate targeting the CD46 protein, demonstrates promising efficacy in treating metastatic castration-resistant prostate cancer (mCRPC). Among patients treated at doses of 1.2 mg/kg or higher, the median radiographic