Search
Search
About
Log in
Join
Experiences with
Antagon
Posts
Communities
11,325 public posts
Filter results
Relugolix/Orgovyx or Enzalutamide/Xtandi?
Good morning, all. I have updated my profile with my husband's history. But, long story short, he has been on ADT vacation for 13 months following succesful treatment of metastatic disease with Triplet Therapy (six rounds of Docetaxel, Lupron, and first Abieraterone plus Prednisone and then he switched
Good morning, all. I have updated my profile with my husband's history. But, long story short, he has been on ADT vacation for 13 months following succesful treatment of metastatic disease with Triplet Therapy (six rounds of Docetaxel, Lupron, and first Abieraterone plus Prednisone and then he switched
FaithOverFear104
in
Advanced Prostate Cancer
5 months ago
WORRIED ABOUT REOCCURRENCE???
Worried....
Stopped IMRT 1 year ago and stopped adt (4 mos) 9 months ago...
9/23/23 Blood Test PSA .1 --- PSA FREE undetectable and Testosterone was 98
3/4/24 Blood Test PSA .2 ----Psa Free Undetectable and Testosterone not in yet.
I am concerned about the increase
Worried....
Stopped IMRT 1 year ago and stopped adt (4 mos) 9 months ago...
9/23/23 Blood Test PSA .1 --- PSA FREE undetectable and Testosterone was 98
3/4/24 Blood Test PSA .2 ----Psa Free Undetectable and Testosterone not in yet.
I am concerned about the increase
JWS13
in
Advanced Prostate Cancer
5 months ago
4 years post EBRT (44) PSA 0.1 Up from undetectable.
MO thinks it will go up hopefully slowly. Recheck psa in 3 months. Dumb question maybe. Stage 4?
MO thinks it will go up hopefully slowly. Recheck psa in 3 months. Dumb question maybe. Stage 4?
Chasu
in
Advanced Prostate Cancer
5 months ago
Want to take advantage of all our features? Just log in!
Log in
or
Join
Pet Scan = "disease not detected"
Ok folks, has anyone come across something like this?...early 2018, PSA in the 50's, biopsy came back negative, a few months later PSA in the 60's, again, another biopsy and a negative finding, 3rd time in the 80's with yet another negative biopsy, then nuclear imaging and bam...stage 4 metastatic, this
Ok folks, has anyone come across something like this?...early 2018, PSA in the 50's, biopsy came back negative, a few months later PSA in the 60's, again, another biopsy and a negative finding, 3rd time in the 80's with yet another negative biopsy, then nuclear imaging and bam...stage 4 metastatic, this
GreyDragon55
in
Advanced Prostate Cancer
5 months ago
Should the dose of Dutasteride be increased?
The plot above shows the residual (nadir) level of DHT in men as a function of the daily Dutasteride dose (mg/day). The DHT nadir numbers shown in this plot are: 23.8 pg/mL for 0.5 mg daily dose; 10.2 pg/mL for 2.5 mg daily dose; and 7.3 pg/mL for 5 mg daily dose. Ref: Clark (2004) [see Table
The plot above shows the residual (nadir) level of DHT in men as a function of the daily Dutasteride dose (mg/day). The DHT nadir numbers shown in this plot are: 23.8 pg/mL for 0.5 mg daily dose; 10.2 pg/mL for 2.5 mg daily dose; and 7.3 pg/mL for 5 mg daily dose. Ref: Clark (2004) [see Table
janebob99
in
Advanced Prostate Cancer
6 months ago
Should the dose of Dutasteride be increased?
The plot above shows the residual (nadir) level of DHT in men as a function of the daily Dutasteride dose (mg/day). The DHT nadir numbers shown in this plot are: 23.8 pg/mL for 0.5 mg daily dose; 10.2 pg/mL for 2.5 mg daily dose; and 7.3 pg/mL for 5 mg daily dose. Ref: Clark (2004) [see Table
The plot above shows the residual (nadir) level of DHT in men as a function of the daily Dutasteride dose (mg/day). The DHT nadir numbers shown in this plot are: 23.8 pg/mL for 0.5 mg daily dose; 10.2 pg/mL for 2.5 mg daily dose; and 7.3 pg/mL for 5 mg daily dose. Ref: Clark (2004) [see Table
janebob99
in
Prostate Cancer Network
6 months ago
How long on Prostap?
I was diagnosed in January2021 with PC. Gleeson 4+3 but PSA only ever up to 10. I have had four PSMA scans which show 8 metastases in skull, ribs, pubic bone, hip bone. These continue to grow. I have been on Aberiterone/prednisolone, plus Prostap every 3 months. I have growing levels of bone pain (
I was diagnosed in January2021 with PC. Gleeson 4+3 but PSA only ever up to 10. I have had four PSMA scans which show 8 metastases in skull, ribs, pubic bone, hip bone. These continue to grow. I have been on Aberiterone/prednisolone, plus Prostap every 3 months. I have growing levels of bone pain (
Stephen399b
in
Advanced Prostate Cancer
6 months ago
PSA still undetectable?
Prostatectomy September 2022. PSA since op 0.01 latest PSA 0.03 Urologist states will check it again in 3 months rather then 6. 0.03 still very low but why the rise. Could the cause be micro prostate cancer cells hiding somewhere? PSMA pet scan pre op all clear apart from the two lesions in Prostate
Prostatectomy September 2022. PSA since op 0.01 latest PSA 0.03 Urologist states will check it again in 3 months rather then 6. 0.03 still very low but why the rise. Could the cause be micro prostate cancer cells hiding somewhere? PSMA pet scan pre op all clear apart from the two lesions in Prostate
Aussieguy1
in
Prostate Cancer And Gay Men
6 months ago
Looking for Estrogen users...
Hello, I'm doing a survey of estrogen users. I'd like to find out: 1. How many patches or gel pumps do you use a day, or a week? And what dose of E2 patches do you use? 2. What's your PSA? 3. What's your estradiol? 4. What's your testosterone? 5. What's your DHT (if you measure it)? 6. How
Hello, I'm doing a survey of estrogen users. I'd like to find out: 1. How many patches or gel pumps do you use a day, or a week? And what dose of E2 patches do you use? 2. What's your PSA? 3. What's your estradiol? 4. What's your testosterone? 5. What's your DHT (if you measure it)? 6. How
janebob99
in
Prostate Cancer Network
6 months ago
Looking for Estrogen Users...
Hello, I'm doing a survey of estrogen users. I'd like to find out: 1. How many patches or gel pumps do you use a day, or a week? And what dose of E2 patches do you use? 2. What's your PSA? 3. What's your estradiol? 4. What's your testosterone? 5. What's your DHT (if you measure it)? 6. How
Hello, I'm doing a survey of estrogen users. I'd like to find out: 1. How many patches or gel pumps do you use a day, or a week? And what dose of E2 patches do you use? 2. What's your PSA? 3. What's your estradiol? 4. What's your testosterone? 5. What's your DHT (if you measure it)? 6. How
janebob99
in
Advanced Prostate Cancer
6 months ago
Low testosterone is associated with extremely poor survival metrics, post-ADT.
These companion plots compare: (A) median survival times, (B) PSA doubling times, and (C) Time to PSA Failure for two different levels of testosterone: Low and Normal. The low testosterone has a median value of 162 ng/dL [120-236] and the average normal T = 680 ng/dL. The cohort is 58 men with unfavorable
These companion plots compare: (A) median survival times, (B) PSA doubling times, and (C) Time to PSA Failure for two different levels of testosterone: Low and Normal. The low testosterone has a median value of 162 ng/dL [120-236] and the average normal T = 680 ng/dL. The cohort is 58 men with unfavorable
janebob99
in
Prostate Cancer Network
6 months ago
My own PSA values over time: 70% drop in just 3 months on Dutasteride and no ADT
Here are my own PSA values versus time plot. You can see there is an exponential rise in PSA starting at around 6/1/23, and doubling from PSA = 5 to 10 in about 8 months. My MRI at PSA = 10 showed a T3a tumor about 1.3 cm long (PIRADS 5). A subsequent targeted biopsy showed Gleason 3+4 in 4 cores,
Here are my own PSA values versus time plot. You can see there is an exponential rise in PSA starting at around 6/1/23, and doubling from PSA = 5 to 10 in about 8 months. My MRI at PSA = 10 showed a T3a tumor about 1.3 cm long (PIRADS 5). A subsequent targeted biopsy showed Gleason 3+4 in 4 cores,
janebob99
in
Prostate Cancer Network
6 months ago
Doubling Times and PSA acceleration - Part II
This is a more realistic schematic plot of PSA levels increasing over time at an ever faster rate (acceleration). What could cause this? My theory is that as the tumor grows, the number of androgen receptors (ARs) increases proportionally. That makes sense...more PCa cells inside a tumor...more ARs
This is a more realistic schematic plot of PSA levels increasing over time at an ever faster rate (acceleration). What could cause this? My theory is that as the tumor grows, the number of androgen receptors (ARs) increases proportionally. That makes sense...more PCa cells inside a tumor...more ARs
janebob99
in
Prostate Cancer Network
6 months ago
PSA levels will increase over time, depending on the level of testosterone - Part I
Here's a schematic plot of the increase in PSA level (or increase in tumor volume) over time, for various levels of testosterone (while the tumor is relatively small). At very low levels of testosterone (for example, T = 10 ng/dL), the increase in PSA level is very small after a given time (for example
Here's a schematic plot of the increase in PSA level (or increase in tumor volume) over time, for various levels of testosterone (while the tumor is relatively small). At very low levels of testosterone (for example, T = 10 ng/dL), the increase in PSA level is very small after a given time (for example
janebob99
in
Prostate Cancer Network
6 months ago
Baseline PSMA-Pet scan?
My MO has given me instructions to end treatment 7/31. I've been on Lupron & Zytiga/5mg prednisone since 8/1/2022. I started out with Gleason (3+4) 7. Last May I had pelvic radiation to hit lymph nodes as per a 2021 PSMA-Pet scan. Now it's time to stop all treatment at the 2 year mark. My MO just kind
My MO has given me instructions to end treatment 7/31. I've been on Lupron & Zytiga/5mg prednisone since 8/1/2022. I started out with Gleason (3+4) 7. Last May I had pelvic radiation to hit lymph nodes as per a 2021 PSMA-Pet scan. Now it's time to stop all treatment at the 2 year mark. My MO just kind
duxlubber
in
Advanced Prostate Cancer
6 months ago
Shawty got low, low, low, & the Beat goes On. PSA update!
https://youtu.be/ckKFxMw6z0c?si=uEmAdIKQg-1jg-Hw https://youtu.be/9lkfrtztqEY?si=EBG_OJ3pB1LcBRQ0 I dunno why it's still droppin' almost a year post 28 IMRTs but I ain't gon complain 😜 Maybe I have Someone to watch over me https://youtu.be/g8J2Gb-hMIY?si=FYnNKgYTgkpdC4ud Life is Beautiful https
https://youtu.be/ckKFxMw6z0c?si=uEmAdIKQg-1jg-Hw https://youtu.be/9lkfrtztqEY?si=EBG_OJ3pB1LcBRQ0 I dunno why it's still droppin' almost a year post 28 IMRTs but I ain't gon complain 😜 Maybe I have Someone to watch over me https://youtu.be/g8J2Gb-hMIY?si=FYnNKgYTgkpdC4ud Life is Beautiful https
dockam
in
Advanced Prostate Cancer
6 months ago
Result of Liver Biopsy - Any Insights?
This is the result of my liver biposy. Any insights on the comment? ----- CLINICAL HISTORY>>:: Prostate Ca with hepatic mets ?Small cell transformation versus other. FINAL DIAGNOSIS>>:: LIVER NODULE, CORE BIOPSY: - POORLY DIFFERENTIATED PROSTATIC ADENOCARCINOMA WITH SMALL CELL TRANSFORMATION
This is the result of my liver biposy. Any insights on the comment? ----- CLINICAL HISTORY>>:: Prostate Ca with hepatic mets ?Small cell transformation versus other. FINAL DIAGNOSIS>>:: LIVER NODULE, CORE BIOPSY: - POORLY DIFFERENTIATED PROSTATIC ADENOCARCINOMA WITH SMALL CELL TRANSFORMATION
skiingfiend
in
Advanced Prostate Cancer
6 months ago
Interesting study on combination of statins and metformin in high-risk patient outcomes
https://www.academia.edu/99363002/Individual_and_joint_effects_of_metformin_and_statins_on_mortality_among_patients_with_high_risk_prostate_cancer?email_work_card=view-paper Interesting paper - basically showing that statins reduce PCa mortality among high-risk PCa patients, metformin doesn't appear
https://www.academia.edu/99363002/Individual_and_joint_effects_of_metformin_and_statins_on_mortality_among_patients_with_high_risk_prostate_cancer?email_work_card=view-paper Interesting paper - basically showing that statins reduce PCa mortality among high-risk PCa patients, metformin doesn't appear
Don_1213
in
Advanced Prostate Cancer
6 months ago
Non metastasis castrate resistant
When you are on ADT and become Non metastatic Castrate resistant and your testosterone levels are below zero, what is the cancer feeding off to cause the PSA to still rise? Hoping for your replies so as to give me some understanding. Thank you.
When you are on ADT and become Non metastatic Castrate resistant and your testosterone levels are below zero, what is the cancer feeding off to cause the PSA to still rise? Hoping for your replies so as to give me some understanding. Thank you.
Sailameme
in
Advanced Prostate Cancer
6 months ago
High risk vs. aggressive cancer
I understand the definition of high-risk prostate cancer (Gleason, PSA and/or spread), but that doesn't necessarily seem to be the same thing as aggressive cancer. How can aggressiveness be determined for high risk, localized cancer? Thanks for any insight and information.
I understand the definition of high-risk prostate cancer (Gleason, PSA and/or spread), but that doesn't necessarily seem to be the same thing as aggressive cancer. How can aggressiveness be determined for high risk, localized cancer? Thanks for any insight and information.
RugbyVLS
in
Advanced Prostate Cancer
6 months ago
1
...
32
33
34
...
100
Next page
10
20
30
40
50
60
70
80
90
100
Filter results
Clear filters
Posted in
All communities
Advanced Prostate Cancer
8984 results
Prostate Cancer Network
1090 results
Fight Prostate Cancer
260 results
View top 10 communities
Sort by
Most Relevant
Newest