Posts - Advanced Prostate Cancer | HealthUnlocked

Advanced Prostate Cancer

21,445 members • 26,866 posts

All posts for June 2024

Estrogens and Castrate/Treatment Resistance?

Has anyone using estrogens (estradiol) as the primary agent of ADT (androgen deprivation therapy) had their prostate cancer become resistant (androgen...

Has anyone using estrogens (estradiol) as the primary agent of ADT (androgen dep...

Lost_Sheep

•9 days ago

20 Replies

Has periodic limb Movement Disorder in sleep - is xtandi ok to start

Dad , 83 , has periodic limb movement disorder ( PLMD ) , during the time when he is going to sleep. Once fully asleep it does not happen. he is supposed...

Dad , 83 , has periodic limb movement disorder ( PLMD ) , during the time when ...

Tinkudi

•9 days ago

19 Replies

QOL- happy first day of summer

https://youtu.be/daxDwrrDdng?si=-3GDRTJ6bxDI64TZ Here’s hoping you have a great summer!

https://youtu.be/daxDwrrDdng?si=-3GDRTJ6bxDI64TZ Here’s hoping you have a great...

MouseAddams

•9 days ago

8 Replies

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Never make the disease more important than the patient

In this one minute video, a nerosugeon presents four concerns he always respects for his patients. https://youtube.com/shorts/_o8kVxkK28Y?si=KaEs2kYep3mJP9f0...

In this one minute video, a nerosugeon presents four concerns he always respects...

Darryl

Partner•10 days ago

2 Replies

Someone had a question about Apixaban?

I had trouble logging in, anyway... I get my Apixaban (generic for Eliquis) from Canada Pharmacy Online at less cost than Eliquis. It has to come through...

I had trouble logging in, anyway... I get my Apixaban (generic for Eliquis) fro...

dixiedad

•10 days ago

8 Replies

When your doctor demeans your symptoms.

Medical gasliighting is real. It's when your health concerns are dismissed by a medical provider, Here's a story from today's NYTimes...

Medical gasliighting is real. It's when your health concerns are dismissed by a...

Darryl

Partner•10 days ago

9 Replies

I must share this only for its title: From Comfort to Cure: 2024 ASCO Meeting Reveals Groundbreaking Oncology Data

Maxone73

•10 days ago

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Drugs repurposing: new research, maybe we will all save some $$$

"...is pleased to announce that in preclinical research, it's lead drug formulation, Rutherrin® was able to repurpose non-cancer drugs for cancer therapy."...

"...is pleased to announce that in preclinical research, it's lead drug formulat...

Maxone73

•10 days ago

3 Replies

Anyone out there start Pluvicto at 85 or older?…Oncologist wants me to try but I’m Hesitant due to side effects possible…

I’m 10 years into the battle …Last 4 1/2 Metastatic….my oncologist wants me to try Pluvicto….Im feeling pretty good right now and can do most things…..I’ve had...

I’m 10 years into the battle …Last 4 1/2 Metastatic….my oncologist wants me to t...

Roxysdad

•10 days ago

9 Replies

some news: new phase 0 trial for new radioligand gives good results

since I am in the waiting room waiting for my PET scan, I am making use of the time ”Unlike PSMA-targeted agents that are accompanied by an uptake in the...

since I am in the waiting room waiting for my PET scan, I am making use of the t...

Maxone73

•10 days ago

17 Replies

Phase 1b: FOR46, a novel antibody-drug conjugate targeting a tumor-specific epitope of CD46, in combination with Enza in patients with mCRPC

"Preliminary anti-tumor activity was observed with PSA declines in 13/16 (81.3%) of evaluable pts, and a disease control rate (stable disease ≥ 6 months) of...

"Preliminary anti-tumor activity was observed with PSA declines in 13/16 (81.3%)...

Maxone73

•11 days ago

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proof of concept CUPID trial finished, moving to 1b/2

"The RADmAb® approach accelerates blood clearance and reduces bone marrow residence time compared with standard monoclonal antibodies (mAbs), while retaining...

"The RADmAb® approach accelerates blood clearance and reduces bone marrow reside...

Maxone73

•11 days ago

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Does this sound right? Any advice appreciated.

My dad, 82 yo male had a previous PSA score that hovered around 3 and then went up to 5. Had MRI/CT which came up clear last year and a prostate biopsy (11...

My dad, 82 yo male had a previous PSA score that hovered around 3 and then went ...

Biddity

•11 days ago

19 Replies

Interesting concept: More effective cancer treatment with iontronic pump

like the drop that carves the rock.... https://www.eurekalert.org/news-releases/1048606

like the drop that carves the rock.... https://www.eurekalert.org/news-releases...

Maxone73

•11 days ago

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Lupron SEs - legs

Appreciate this forum and all whom post. I’m amidst 2-year course of Lupron and experiencing persistent leg pain, worst in both Achilles tendons and calves....

Appreciate this forum and all whom post. I’m amidst 2-year course of Lupron and ...

NickKnick

•11 days ago

21 Replies

Overcoming Pneumonia Susceptibility

I flunked my first docetaxel infusion in late 2022 and a week later developed pneumonia resulting in me carried by ambulance to the hospital. As I said in my...

I flunked my first docetaxel infusion in late 2022 and a week later developed p...

TuffNuttoCrack

•11 days ago

2 Replies

Chemo Stopped working what's next? T Cell Therapy?

To Believe it I have been told once the chemo stops working the next step is the T Cell Therapy have you done any research on this talk to your doc and see if...

To Believe it I have been told once the chemo stops working the next step is the...

Praying2BHealthy

•11 days ago

1 Reply

Castrate Resistant

I know that patients who were started at beginning with combo of, say, Lupron plus abiraterone acetate are declared castrate resistant when PSA rises in...

I know that patients who were started at beginning with combo of, say, Lupron pl...

dhccpa

•11 days ago

54 Replies

DO YOU TRUST YOUR DOCTOR : Free registration at https://malecare.org/trust-in-healthcare

Malecare and Prostate Cancer Research (UK) Virtual Conference: TRUST AND HEALTHCARE WEDNESDAY, JUNE 26, 2024 on Youtube.com/Malecare 12 PM ET to 6:10 PM ET...

Malecare and Prostate Cancer Research (UK) Virtual Conference: TRUST AND HEALTH...

Darryl

Partner•11 days ago

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Phase 1: CBP-1018 interesting because it targets bone metastasis as well!

I will keep an eye on this (I am running out of eyes!) preliminary results look promising...

I will keep an eye on this (I am running out of eyes!) preliminary results look...

Maxone73

•11 days ago

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Phase 2 trial: Evaluation of Treatment Interruption After Response in mHSPC

"Patients are allowed to enrolle if they have a stable or falling prostate-specific antigen (PSA) level below 0.2 ng/mL and a castrate testosterone level under...

"Patients are allowed to enrolle if they have a stable or falling prostate-speci...

Maxone73

•11 days ago

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I might have discovered a hidden gem: Clinical Investigators Provide Perspectives on the Current and Future Management of Prostate Cancer

Very interesting, especially because there are big names talking from their direct experiences as practitioners......

Very interesting, especially because there are big names talking from their dire...

Maxone73

•11 days ago

14 Replies

Radioligand Therapy May Improve Radiographic Progression–Free Survival in Taxane-Naive Patients With Advanced Prostate Cancer

Too late for me...but it looks like Pluvicto (and I think radio ligands in general) is moving up in the ladder to reach the first line treatment option...

Too late for me...but it looks like Pluvicto (and I think radio ligands in gener...

Maxone73

•11 days ago

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Should I do chemotherapy?

New here. I am 81 and was diagnosed last month with PCa metastatic to a few bones. Gleason 9. PSA 21 at diagnosis. Have been put on orgovyx and...

New here. I am 81 and was diagnosed last month with PCa metastatic to a few bo...

Simpson80

•11 days ago

10 Replies

pathology report

my dad got his pathology report following prostatectomy what does this all mean doesn’t look confirming

my dad got his pathology report following prostatectomy what does this all mean ...

Chepina23

•12 days ago

24 Replies

Just a quick question.

Hi everyone and thanks for all your help so far. As the chemo has now stopped working for Martin we are looking for any other options that might be available...

Hi everyone and thanks for all your help so far. As the chemo has now stopped ...

Believeit

•12 days ago

6 Replies

When to Commence ADT and/or Androgen Blocking Therapy?

Greetings All - New to this forum but have followed the Healing Well PC forum since beginning treatment in 2018 and later began to follow Prostate Cancer...

Greetings All - New to this forum but have followed the Healing Well PC forum ...

Biochem

•12 days ago

5 Replies

CC260 selective PI5P4Kα and PI5P4Kβ inhibitor

Hii I was going through some article regarding prostate cancer and found that some CC260 , a drug that attacks PI5P4Kα is under research . Many cases of...

Hii I was going through some article regarding prostate cancer and found that ...

jeetu_g27

•12 days ago

5 Replies

update about CB-307 (CB307) for mCRPC: phase 1 trial recruiting

"...a novel half-life extended CD137 x PSMA Humabody for the selective activation of tumour-specific T cells exclusively within the tumour microenvironment....

"...a novel half-life extended CD137 x PSMA Humabody for the selective activatio...

Maxone73

•12 days ago

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AI to predict clinical trials outcome

"Dr. Sabbagh explains that traditional endpoints like overall survival often require long follow-ups, delaying access to potentially life-saving treatments....

"Dr. Sabbagh explains that traditional endpoints like overall survival often req...

Maxone73

•12 days ago

Be the first to reply

Posts - Advanced Prostate Cancer | HealthUnlocked

Advanced Prostate Cancer

All posts for June 2024

Estrogens and Castrate/Treatment Resistance?

Has periodic limb Movement Disorder in sleep - is xtandi ok to start

QOL- happy first day of summer

Never make the disease more important than the patient

Someone had a question about Apixaban?

When your doctor demeans your symptoms.

I must share this only for its title: From Comfort to Cure: 2024 ASCO Meeting Reveals Groundbreaking Oncology Data

Drugs repurposing: new research, maybe we will all save some $$$

Anyone out there start Pluvicto at 85 or older?…Oncologist wants me to try but I’m Hesitant due to side effects possible…

some news: new phase 0 trial for new radioligand gives good results

Phase 1b: FOR46, a novel antibody-drug conjugate targeting a tumor-specific epitope of CD46, in combination with Enza in patients with mCRPC

proof of concept CUPID trial finished, moving to 1b/2

Does this sound right? Any advice appreciated.

Interesting concept: More effective cancer treatment with iontronic pump

Lupron SEs - legs

Overcoming Pneumonia Susceptibility

Chemo Stopped working what's next? T Cell Therapy?

Castrate Resistant

DO YOU TRUST YOUR DOCTOR : Free registration at https://malecare.org/trust-in-healthcare

Phase 1: CBP-1018 interesting because it targets bone metastasis as well!

Phase 2 trial: Evaluation of Treatment Interruption After Response in mHSPC

I might have discovered a hidden gem: Clinical Investigators Provide Perspectives on the Current and Future Management of Prostate Cancer

Radioligand Therapy May Improve Radiographic Progression–Free Survival in Taxane-Naive Patients With Advanced Prostate Cancer

Should I do chemotherapy?

pathology report

Just a quick question.

When to Commence ADT and/or Androgen Blocking Therapy?

CC260 selective PI5P4Kα and PI5P4Kβ inhibitor

update about CB-307 (CB307) for mCRPC: phase 1 trial recruiting

AI to predict clinical trials outcome

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