Phase 1b: FOR46, a novel antibody-dru... - Advanced Prostate...

Advanced Prostate Cancer

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Phase 1b: FOR46, a novel antibody-drug conjugate targeting a tumor-specific epitope of CD46, in combination with Enza in patients with mCRPC

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"Preliminary anti-tumor activity was observed with PSA declines in 13/16 (81.3%) of evaluable pts, and a disease control rate (stable disease ≥ 6 months) of 41.2%"

But side effects could be very hard on heavily pretreated patients

ascopubs.org/doi/10.1200/JC...

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