using fenben

[KieranEdwards]

i'm looking for an effective dosage for fenben use

[JohnInTheMiddle]

Maybe zero? If you can't figure it out from all the material available, then maybe it's not a good idea. There are a lot of risks apparently.

[Lost_Sheep in reply to JohnInTheMiddle]

What are the specific risks that you know of? I have read they are minimal for humans. Without legitimate clinical evidence I am unlikely to try this, but if KieranEdwards wants to be a study of one...

[conagher in reply to Lost_Sheep]

I wrote a long reply. Guess its lost in space. 2 years on fenben no side effects. I did kill 3 Mets L5, left rib and one lymph node. I'm 79

[pakb in reply to conagher]

What leads you to believe it was fenben that killed your mets? Have you been on no other treatments?

[conagher in reply to pakb]

I had been on Casodex during that time. But the Casodex stopped working. PET scan just before Radiation showed no left rib no lymph node and L5 inactive. I was on Fenben with the approval of my MO. I did SBRT to L5 as a precaution. Off of Fenben until last month. Back on it because of new spot on prostate and a new lymph node.

With 2 other cancers this one is the hardest to kill. I'm not stopping the Fenben and pushing for PSMA-617.

VA waited until it Mets before doing anything and the only sent me to a MO on the outside because I don't trust VA healthh care. Long story.

[JohnInTheMiddle in reply to Lost_Sheep]

I don't have the time or the inclination to do the some research to list the risks of fenben. I had noticed, with even a little enthusiasm, the number of people who wrote about it and promoted it even.

So I did some of my own reading and then after a while I realized this is beyond the level of risk that I'm willing to take.

So for anyone writing about it here it's on them to show serious research why fenben is not a risk.

And I wrote a slightly sharp comment here because I want to highlight for naive newbies who also desperately want to live that they should think twice or three times before considering fenben.

[conagher in reply to JohnInTheMiddle]

You want scientific research well you wont get any. Why because big phra cant make the money. Big money and I mean big money with the treatments.

I feel I've had good results along with other PCa guys.

You want medical proof you'll never get it. I'm living proof it hasn't hurt me.

[JohnInTheMiddle in reply to conagher]

Good point about the fact that Pharma can't make money on fenben. But that's not an argument for safety. I used to take antioxidants in the 90s. Supplement companies have a different business model and make money on cheap supplements.

It turns out that taking antioxidants might even have contributed to the development of my prostate cancer.

A single person's experience and anecdotal evidence is not much evidence of anything. I did some reading about fenben and came away very concerned.

[Mgtd in reply to conagher]

Congrats on your results. However that does not mean it should be a standard of care without research and scientific evidence to support its use.

[conagher in reply to Mgtd]

We'll never get the research on Fenben. Why because Big Pharm is make billions on treatments. They feel they can't make money on a cure. Funeral homes will never go broke. Same with the medical industry. There will always be the next cancer patients. We are no longer patients. We are called customers now.

I've been fighting cancers for 14 years and if Fenben helps just a little with NO side effects then I'm all for it. Same with SourSop.

[dhccpa in reply to JohnInTheMiddle]

I think the risk is low, honestly. But gauging the effectiveness? Much tougher, especially while on Lupron. Stay tuned. How long? Can't say!

[Lost_Sheep in reply to JohnInTheMiddle]

I understand that you do not want to spend time researching to find the risks of fenbendazole. I have spent the last 14 months full-time researching (my particular brand of) prostate cancer and treatments. It can be a time sink.

I do wonder if, in the knowledge base you can recall easily, anything you can share about where you found mention of the "level of risk" you are willing to take. Is it just the absence of assurance of safety, or was there something specific?

[JohnInTheMiddle in reply to Lost_Sheep]

Hi Lost! Your comment about a time sync is fantastic. I've heard it said that when you're diagnosed with metastatic PCa you become the CEO of Cancer Inc. Not everybody wants to do the deep dive; and there are many reasons for this. Including already being overloaded is responsibilities, and then there's the possibility of brain fog!

Your question about my reluctance to pursue fenben is a good one - is it because I discovered research and analysis concerning risks? Or was it just as skepticism and concern about a lack of research?

I have both. Sadly I can't remember the risks I turned up! With everything on my plate I just said this isn't a path I want to pursue right now. Although at the beginning there are some attractive things about it for sure.

[Lost_Sheep in reply to JohnInTheMiddle]

John, thanks for your candor. I have the skepticism because of the lack of legitimate, sound research. The actor Steve McQueen pursued "alternative" treatment and I mourn his loss (I liked him as an actor.) and there is great danger in abandoning proven treatments. But I feel an attraction to fenbendazole for its glowing anecdotal reports (which I find encouraging, but not compelling, nor convincing).

I am using Orgovyx/relugolix, but lobbying hard for high-dose trans-dermal estradiol instead (based on the PATCH study, Ockrim's research, N. Russel's research, the VACURG study and many other clinical trials I have found in the past 14 months)

[Professorgary in reply to Lost_Sheep]

While Steve McQueen did pursue alternative treatment, he was dying and told by his US doctors they could do no more for him. He died of a heart attack from a surgery to remove a 5inch tumor in his abdomen. He was told by his US and Mexican doctors it was too risky but insisted upon the removal.

[dhccpa]

There is no normal dose. I started with 222 mg daily, then shifted to 750 or so mg twice daily for 3-4 days each week, pausing for rest of each week. I've varied that over the years, on it 4.5 years now.

I also have used Lupron for 5.5 years now, I hasten to add.

[j-o-h-n]

As per Mr. A and Mrs. i,

Fenbendazole is a broad-spectrum anthelmintic (anti-parasitic) drug that is commonly used in veterinary medicine to treat a variety of parasitic infections in animals. It belongs to the benzimidazole class of medications and works by interfering with the energy metabolism of parasites, leading to their death.

Uses in Veterinary Medicine

Fenbendazole is primarily used to treat parasitic infections in animals, including:

Dogs and Cats:

Roundworms (Toxocara canis, Toxocara cati)

Hookworms (Ancylostoma caninum, Ancylostoma tubaeforme)

Whipworms (Trichuris vulpis)

Tapeworms (Taenia pisiformis)

Giardia: An intestinal protozoan parasite

Livestock:

Cattle, Sheep, and Goats: Used to treat gastrointestinal parasites such as roundworms, lungworms, and certain types of tapeworms.

Horses: Effective against large strongyles, small strongyles, pinworms, and ascarids.

Poultry:

Used to treat various parasitic infections, including gapeworms, roundworms, and cecal worms.

Mechanism of Action

Fenbendazole works by binding to the beta-tubulin protein in the parasites' cells, which disrupts the formation of microtubules. Microtubules are essential for the parasites' energy metabolism and cellular structure. The disruption of these structures leads to the parasites' inability to absorb nutrients, ultimately causing their death.

Dosage and Administration

The dosage of fenbendazole varies depending on the type of animal, the specific parasitic infection being treated, and the formulation of the medication. It is available in various forms, including oral suspensions, granules, and tablets. Veterinary guidance is essential to determine the correct dosage and duration of treatment for each specific case.

Safety and Side Effects

Fenbendazole is generally considered safe when used as directed. Side effects are rare but may include:

Mild Gastrointestinal Distress: Such as vomiting or diarrhea.

Allergic Reactions: Rarely, animals may experience an allergic reaction to fenbendazole.

Temporary Increase in Liver Enzymes: Occasionally observed in some animals.

Human Use and Research

In recent years, fenbendazole has garnered attention for its potential use in cancer treatment. Some preliminary studies and anecdotal reports suggest that it might have anti-cancer properties. However, it is important to note:

Lack of Robust Clinical Evidence: While some studies suggest potential anti-cancer effects, large-scale, controlled clinical trials in humans are lacking.

Off-Label Use: Any use of fenbendazole in humans should be approached with caution and under medical supervision, as it is primarily formulated for veterinary use.

Conclusion

Fenbendazole is a well-established antiparasitic drug used widely in veterinary medicine to treat a variety of parasitic infections in animals. It is known for its efficacy and safety profile when used as directed. While there is some interest in its potential applications in human medicine, particularly in cancer treatment, more research is needed to validate these uses. If considering fenbendazole for off-label use, it is crucial to consult with a healthcare professional to ensure safety and efficacy.

Your Question:

An effective dosage for fenben use

Do you mean by the scoop or by the sack?

Good Luck, Good Health and Good Humor.

j-o-h-n

[JRLDH in reply to j-o-h-n]

I kinda understand if people want to try it if they don't have insurance.

Its method of action is similar to Taxanes. So it can have a similar effect, killing off dividing cells.

With insurance, I think it's puzzling that anyone would consider a drug like that. Zero safe dosing info combined with zero scientific data on efficacy on a specific (!) cancer.

Most prostate cancer (except late stage heavily mutated) divides so slowly that it's statistically unlikely that a chemo drug will have a noticeable effect. Fenben and the other superstar dewormer may kill off a handful of coincidentally dividing cancer cells while offing other dividing cells causing various side effects nilly willy. Not a smart choice.

If you have insurance and your cancer is in a state where a Taxane may actually have a significant effect, your MO will prescribe Doctaxel or Cabazitaxel , which have been studied for prostate cancer.

[j-o-h-n]

Greetings KieranEdwards, Would you please be kind enough to include your bio details in your bio section. All information is voluntary but it helps us help you and helps us too. Thank you!

Good Luck, Good Health and Good Humor.

j-o-h-n

[Professorgary]

if you are interested in learning more about fen Ben I suggest you join the FB group Mycancerstory.rocks.

[Dban]

I looked in depth at fenben and came away from the various groups u scanned without a single ‘positive progress’ story for PC that could be entirely or largely attributed to Fenben. I understand its action but I am wary of taking it at my oligo stage in case of enabling the PC to work around it and other things. Not against it as such but feel it’s a risk and also likely to the liver. That said, close relatives of fenben - like medbendazole- are in use in humans and subject to study. There was a 2024 study around and this news medicalxpress.com/news/2020...

[Dban]

ncbi.nlm.nih.gov/pmc/articl...

There is a more current study fir breast cancer here

ncbi.nlm.nih.gov/pmc/articl....

Also the COC protocol uses it search for that