Posts - Advanced Prostate Cancer | HealthUnlocked

Advanced Prostate Cancer

22,077 members • 27,704 posts

All posts for February 2021

Metformin and Androgen Receptor-Axis-Targeted (ARAT) Agents Induce Two PARP-1-Dependent Cell Death Pathways in Androgen-Sensitive PCa Cells.

New study below [1]. This is a cell study, but it provides a rationale for using Metformin with Abiraterone/Enzalutamide, i.e. androgen receptor-axis-rargeted...

New study below [1]. This is a cell study, but it provides a rationale for using...

pjoshea13

•4 years ago

29 Replies

How Deep Is Your Love

It’s was early 1978, (Saturday night fever was recently released on Dec 14 Th, 1977. Peter and I had individually gone to see this movie several times to...

It’s was early 1978, (Saturday night fever was recently released on Dec 14 Th, 1...

betterlivingbeing

•4 years ago

39 Replies

Today I Am Celebrating My 4yr Anniversary Of Having Prostate Cancer🎉

I was diagnosed with prostate cancer on February 13th, 2017. It was stage IV and had metastasized. Not the kind of news you want to receive just five days...

I was diagnosed with prostate cancer on February 13th, 2017. It was stage IV and...

Urunstoppable

•4 years ago

33 Replies

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Decision Time

Getting ready to make a treatment decision now that all my tests are in. Age 64 Good health Stage T2C Gleason 6/7 (3+3 and 3+4) Total body bone - nothing...

Getting ready to make a treatment decision now that all my tests are in. Age 64...

NickyDJr

•4 years ago

7 Replies

Finding a good Medical Team

PSA was elevated in October. Couldn't see for 3 weeks, biopsy Gleason 10. Appointment with surgeon took 3 weeks after having bone scan and MRI. I was...

PSA was elevated in October. Couldn't see for 3 weeks, biopsy Gleason 10. Appo...

Vangogh1961

•4 years ago

10 Replies

Survival of Prostate Cancer Patients Is Increased by Melatonin

https://www.oncotarget.com/article/27757/text/

dexy1234

•4 years ago

27 Replies

225AC PSMA617 treatment any idea?

225AC PSMA617 anyone have idea about this? When should be done or survival benefits etc before chemo or after chemo?

225AC PSMA617 anyone have idea about this? When should be done or survival benef...

Nirman

•4 years ago

10 Replies

Chart of various options for treatment

This may be wishful thinking, but has anyone in this forum developed a flow chart or other organized system indicating the various paths men may consider at...

This may be wishful thinking, but has anyone in this forum developed a flow char...

lss65

•4 years ago

10 Replies

Cyclophosphamide for mCRPC???

Hello everyone, I had once consulted an oncologist who suggested that my father could try oral cyclophosphamide (metronomic therapy) when abiraterone...

Hello everyone, I had once consulted an oncologist who suggested that my father...

Vsahay

•4 years ago

5 Replies

Xtandi shortage

The Air Force pharmacy has been unable to get Xtandi since December. Luckily I had enough until now. I have checked with all the off base pharmacies and no...

The Air Force pharmacy has been unable to get Xtandi since December. Luckily I ...

bunny91

•4 years ago

3 Replies

Zytiga did not Work - Chemo or RA 223 Next

Question for all you warriors. Have you had Zytiga fail? Yesterday I met with my MO and he reviewed the results of my PSA - now 15 - up from 4 - ninety...

Question for all you warriors. Have you had Zytiga fail? Yesterday I met wi...

Hidden

•4 years ago

81 Replies

Why continue LUPRON when ADT not working?

I have castration resistant prostate cancer with a Testosterone level of 6. I am not sure why I am still taking Lupron when it is clearly not working? Ideas?...

I have castration resistant prostate cancer with a Testosterone level of 6. I am...

baltha

•4 years ago

11 Replies

The Patch Trial...the verdict is in!

Transdermal oestradiol for androgen suppression in prostate cancer: long-term cardiovascular outcomes from the randomised Prostate Adenocarcinoma...

Transdermal oestradiol for androgen suppression in prostate cancer: long-term ca...

E2-Guy

•4 years ago

48 Replies

Emsella, has anyone with incontinence tried it?

I have been incontinent over one year since my RALP. Someone recently suggested trying a treatment called Emsella. Has anyone had any experience with it? I...

I have been incontinent over one year since my RALP. Someone recently suggested ...

Iupiter

•4 years ago

2 Replies

The Mutational Landscape of Metastatic Castration-Sensitive Prostate Cancer: The Spectrum Theory Revisited

Published in Advanced Prostate Cancer Journal Scan / Research · February 09, 2021 The Mutational Landscape of Metastatic Castration-Sensitive Prostate Cancer:...

Published in Advanced Prostate Cancer Journal Scan / Research · February 09, 202...

podsart

•4 years ago

7 Replies

Another British Breakthrough

https://www.theguardian.com/society/2021/feb/11/new-prostate-cancer-scan-could-replace-invasive-exam-and-save-lives

https://www.theguardian.com/society/2021/feb/11/new-prostate-cancer-scan-could-r...

dexy1234

•4 years ago

18 Replies

Optimal Management of a Man With Recurrent Prostate Cancer

Here is a case summary from Practice Update and it would be interesting to see the opinions of the more well-informed minds on this forum regarding this case....

Here is a case summary from Practice Update and it would be interesting to see t...

Balsam01

•4 years ago

10 Replies

PSA Tracker

I have spent a bit of time this morning putting my PSA readings into a graph and then annotating the major treatments. I find it quite interesting and so...

I have spent a bit of time this morning putting my PSA readings into a graph and...

Teddysdad

•4 years ago

20 Replies

Have I really reached the last hitching post. Its truly surreal.

At the risk of being mellow dramatic, I have recently been disqualified from a clinical trial bombesin) due to lack of expression on the Psma pet scan,...

At the risk of being mellow dramatic, I have recently been disqualified from a ...

Costarica1961

•4 years ago

20 Replies

Replacement Sling-burnett1948

I had a Sling inserted in 2012. It improved my incontinence then. But my incontinence is now bad. Has any body had a replacement sling or a new sling.

I had a Sling inserted in 2012. It improved my incontinence then. But my inconti...

Burnett1948

•4 years ago

4 Replies

PSMA PET/CT vs CT Alone in Newly Diagnosed Biochemical Recurrence of Prostate CancerEuropean Journal of Radiology

https://www.practiceupdate.com/c/113205/1/3/?elsca1=emc_enews_expert-insight&elsca2=email&elsca3=practiceupdate_uro&elsca4=urology&elsca5=newsletter&rid=NDE4MjA

https://www.practiceupdate.com/c/113205/1/3/?elsca1=emc_enews_expert-insight&els...

maley2711

•4 years ago

3 Replies

His parotid glands are swollen, I am worried all the time. Dealing with anxiety.

This question is not so much about the treatment, but I am asking how to just emotionally deal with it. My ex got the cancer. Lots of plans that I/we made are...

This question is not so much about the treatment, but I am asking how to just em...

Choice125

•4 years ago

4 Replies

Doctor refuses to test for AR-V7

I have tried three times to get my husband's MO to request an AR-V7 test. The doctor says that since hubby progressed on both Abiraterone and Xtandi the test...

I have tried three times to get my husband's MO to request an AR-V7 test. The do...

WildRose6

•4 years ago

15 Replies

Docetaxel vs. Cabazitaxel--effectiveness?

Hi everyone, Hubby just finished second round of docetaxel on Dec. 31st. Last year he tried both Abiraterone and Xtandi but PSA is still rising, even after...

Hi everyone, Hubby just finished second round of docetaxel on Dec. 31st. Last ye...

WildRose6

•4 years ago

11 Replies

Another stable guy from MA

Like Tom of MA, the scans for my road warrior from MA came back as stable. He hadn't had a CT or bone scan since June, 2020 because he broke his collarbone...

Like Tom of MA, the scans for my road warrior from MA came back as stable. He ...

spouse21

•4 years ago

14 Replies

PSA rises from 0.3 to 0.4 - should I be concerned?

First diagnosed in December 2018 with PSA at 7.57. Went on ADT (lupron, zytiga, prednisone) and numbers dropped through 2019 and into 2020 with last few...

First diagnosed in December 2018 with PSA at 7.57. Went on ADT (lupron, zytiga,...

JazzMan42

•4 years ago

23 Replies

Who here is on Keytruda or other checkpoint inhibitor or some kind of immunotherapy?

Hello everyone. I have been on Keytruda for about 43 infusions now first done every three weeks but every six weeks as of late last year. I am MSI-High with...

Hello everyone. I have been on Keytruda for about 43 infusions now first done ...

Fuzzman77

•4 years ago

40 Replies

Bone Marrow Failure After 2 Rounds of Ra223

I was diagnosed and had a radical removal in Nov 2010 with Gleason 7 and one lymph node involved. In the past 2 years I have been through abiraterone then the...

I was diagnosed and had a radical removal in Nov 2010 with Gleason 7 and one lym...

Trengle

•4 years ago

5 Replies

Next step!

My father has been on LU-177 therapy since March 2020.However, he had not taken the doses as per schedule(every 2 months) .As a result he got his 3rd dose on...

My father has been on LU-177 therapy since March 2020.However, he had not taken ...

Vsahay

•4 years ago

6 Replies

Experiencing different side-effects across Lupron injections

I’ve had Lupron injections twice so far, once in April 2020 and a second time in early Jan 2021. My side-effects are not uncommon in themselves, but I am...

I’ve had Lupron injections twice so far, once in April 2020 and a second time in...

Mascouche

•4 years ago

47 Replies

Posts - Advanced Prostate Cancer | HealthUnlocked

Advanced Prostate Cancer

All posts for February 2021

Metformin and Androgen Receptor-Axis-Targeted (ARAT) Agents Induce Two PARP-1-Dependent Cell Death Pathways in Androgen-Sensitive PCa Cells.

How Deep Is Your Love

Today I Am Celebrating My 4yr Anniversary Of Having Prostate Cancer🎉

Decision Time

Finding a good Medical Team

Survival of Prostate Cancer Patients Is Increased by Melatonin

225AC PSMA617 treatment any idea?

Chart of various options for treatment

Cyclophosphamide for mCRPC???

Xtandi shortage

Zytiga did not Work - Chemo or RA 223 Next

Why continue LUPRON when ADT not working?

The Patch Trial...the verdict is in!

Emsella, has anyone with incontinence tried it?

The Mutational Landscape of Metastatic Castration-Sensitive Prostate Cancer: The Spectrum Theory Revisited

Another British Breakthrough

Optimal Management of a Man With Recurrent Prostate Cancer

PSA Tracker

Have I really reached the last hitching post. Its truly surreal.

Replacement Sling-burnett1948

PSMA PET/CT vs CT Alone in Newly Diagnosed Biochemical Recurrence of Prostate CancerEuropean Journal of Radiology

His parotid glands are swollen, I am worried all the time. Dealing with anxiety.

Doctor refuses to test for AR-V7

Docetaxel vs. Cabazitaxel--effectiveness?

Another stable guy from MA

PSA rises from 0.3 to 0.4 - should I be concerned?

Who here is on Keytruda or other checkpoint inhibitor or some kind of immunotherapy?

Bone Marrow Failure After 2 Rounds of Ra223

Next step!

Experiencing different side-effects across Lupron injections

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