Hi everyone! I've been reading a lot on this site over the past few months and it's been extremely helpful and was wondering if everyone could help me with a few questions. I know you (mostly) ladies like full stories and full ranges, so here's mine.
I'm a 38 yr old female in the states, NYC. I hadn't been feeling well for about a year. Extremely tired, dizzy, gaining weight, memory fog, cold, etc. I went into a walk-in clinic at night in Nov. 2017 and got my thyroid (among other things tested) and these were the results:
TSH 2.45 .36-4.42
T3, Total 100 60-181
T4, Free .98 .80-1.8
At the time, I didn't know about optimal ranges so I figured I didn't have a thyroid problem. I then went for my yearly gynecologist exam on 2/21/18 at night and asked her to test my thyroid while I was there again. Here are the results:
TSH 2.880 .27-4.2
T4, Free .84 .93-1.70abnormal
T3, Free 2.9 2.00-4.40
My T4 came back abnormal, but my gynecologist said that I probably didn't need to go to an endo because it was slightly abnormal. Meanwhile, I still felt horrible and was getting worse and gaining weight. I picked an endo near me without knowing that some endos are diabetes specialists who don't know much about thyroid problems. I went to her on 3/23/18 in the afternoon and these are the results.
TSH 1.97 0.4-4.5
T4, Free 0.9 0.8-1.8
Thyroid Peroxidase Ab <1 <9
Thyroglobulin Antibodies <1 < or = 1
This endo said there was nothing wrong with me, and because I didn't have antibodies, I likely didn't have a thyroid problem (which is flat out wrong). At this point, I started researching what was going on with me and found this site and stop the thyroid madness. I looked into going to another endo, this time a friend's thyroid specialist. I went to him on 4/9/18. He thought I might have secondary hypothyroidism and also tested my cortisol. These are the results from an 8 AM testing:
TSH 3.45 .4-4.5
T4, Free 1 0.8-1.8
T3, Free 3.6 2.3-4.2
Cortisol, Total 17.1 4.0-22 in AM
ACTH, Plasma 23 6-50 pg/ml
Based on these results, he said he wouldn't treat me, but that another endo would likely treat me. Apparently there are some US doctors that follow the strict ranges, and some that follow the optimum ranges, that a TSH of 2+ likely is hypothyroidism. At this point, I was pretty distraught over how endos don't prescribe unless a TSH is over 5 (but I know UK people have it worse!). I did more research on STTM and finally went to a doctor who writes on STTM (I live in NYC, plus my insurance covered him. I'm extremely lucky.). He looked at my prior results and said that I 100% had a thyroid problem and started me on 1 grain of NDT (Armour) immediately. He also tested everything and these are those results from 4/25/18 mid-day:
TSH 1.53 0.4-4.5
T4, Free 0.9 0.8-1.8
T4, Total 4.0 4.5-12abnormal
T3, Total 86 76-181
T3, Free 3.0 2.3-4.2
T3, Reverse 9 8-25
Vit B12 631 200-1100
Thyroid Peroxidase Ab 1 <9
Thyroglobulin Antibodies <1 < or = 1
Vit D, 25-OH, Total, IA 54 30-100
He also did an ultrasound with the above bloodwork and the first thing the ultrasound technician said was, "How much NDT are you on because you need an increase, you have a lot of nodules." I ended up having 6 nodules, the largest was .6 mm. So he put me on one grain, and told me to come back in two weeks for more bloodwork. I went back on 5/9 and I still felt pretty bad, probably even a little bit worse. The dizziness was the worst- I would stay at work until 7 PM just so I could get a seat on the subway after rush hour. He raised me to 2 grains of Armour and took the following bloodwork in the morning (fasting, no NDT prior). He told me to come back in 3 weeks.
TSH .31 0.4-4.5abnormal but should be b/c suppressed
T4, Total 3.5 4.5-12abnormal
T3, Total 74 76-181abnormal
Thyroid Peroxidase Ab <1 <9
Thyroglobulin Antibodies <1 < or = 1
Vit D, 25-OH, TOTAL, IA 66 30-100
Vit B12 483 200-1100
Iron, Total 80 40-190
Iron Binding Capacity 296 250-450
% Saturation 27 11-50%
Ferritin 70 10-154
I went back 3 weeks later, on 5/30/18 and still didn't feel that great on 2 grains of NDT, so he raised me to 3 grains and did no bloodwork. He also gave me 1,000 cc's of vit B-12 shots to take every 2 weeks. This doctor is great, I'm extremely lucky to find him, he tests for everything and works with me. He told me to come back in 3 more weeks and we'd do bloodwork then. I went back on 6/21/18 and felt pretty good. I wasn't tired all the time, no longer freezing, my memory was slowly coming back, etc. We didn't raise my NDT but he did more bloodwork and said we would talk when we got the bloodwork back. Here's the 6/21/18 bloodwork (morning, fasting, no NDT):
TSH .0015 0.35-3.0
T3, Total 120.88 82-190
T4, Total 5.70 4.87-11.72
Vit B12 1062 >500
The doctor and I spoke and he said that my T3 was adequate. I asked him if I could go to 4 grains, because the T3 wasn't in the top 3/4 of the range and I wasn't losing weight (I had gained 20 pounds over the last year) and perhaps I would feel even better on 4 grains. He said it was fine to go to 4 grains and to come back in 3 months for more bloodwork. He also said that if I started to feel hyper to decrease by a grain immediately.
So I'm 5 weeks in on 4 grains of NDT and I feel really great. I'm extremely alert, not tired and not gaining weight anymore although not losing any either. Thanks for reading this extremely long post but I thought I'd try to cover any questions preemptively that you may ask about vitamins, cortisol, AM testing, etc. These are my questions:
1. Does the presence of nodules on my thyroid show that I definitely have Hashimotos or just thyroid problems? I don't have antibodies, but am I in that 10-20% that doesn't?
2. Is a TSH fluctuation of +2 considered normal (i.e. 1.5-3.5)? Does this mean I have hashimotos?
3. In the morning when I wake up, I check my pulse (I have a sleep app that does it). It is usually between 90-100 bpm in the morning, and pretty much around that through most of the day. Is that normal or does that mean I am on too much NDT? Since I've increased to 4 grains, I've gotten 1-2 heart palpitations a week, but that hasn't happened in a week or so. I've been on 4 grains for 5 weeks, so is it possible that was just my body getting used to the 4 grains?
4. Is 4 grains a high dose? I feel like most posts with people on NDT usually stop at 3 grains.
5. When can I start exercising? A lot of posts state that you should wait until you're optimal before you start exercising. I'm pretty lazy, but I just tried to go for a jog in the park and my heart felt like it was beating fast. I came home and I tested my bpm 30 minutes after exercise and it was 120 bpm.
6. When does weight loss typically start happening after optimal dosing?
Thanks everyone for reading this really long post and thanks for writing your own posts! This forum has helped me so much over the past few months.