Increased levo feeling worse: Apologies in... - Thyroid UK

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Increased levo feeling worse

MrsR14 profile image
4 Replies

Apologies in advance for my very long post. Feeling really down and would love some advice if anyone can help.

3 months taking 25mcg of levo I noticed a slight improvement in some symptoms, noticeably my mood and the fatigue. I started my increased dose of 50mcg a week ago and I am feeling awful again. So emotional and exhausted. I sort of feel like I have a constant hangover. I have taken the last two days off work (feeling very guilty about taking time off) and still exhausted whilst doing nothing! Has anyone else experienced symptoms worsening when changing doses?

I have also been prescribed Vitamin D and calcium supplements. Vit D is 800mg a day, is this dosage high enough? Doctor said all other vitamin levels are fine.

Blood results

Serum parathyroid hormone 5.400 pmol/L 1.95 - 8.49 pmol/L

Bone profile Serum alkaline phosphatase 36.000 U/L 46 - 116 U/L Serum calcium 2.220 mmol/L 2.15 - 2.6 mmol/L Serum adjusted calcium conc 2.180 mmol/L 2.2 - 2.62 mmol/L Serum inorganic phosphate 0.950 mmol/L 0.8 - 1.5 mmol/L Serum albumin 43.000 g/L 34 - 50 g/L

Serum free T4 level 17.000 pmol/L 10 - 18.7 pmol/L

Serum iron tests Serum iron level 25.500 umol/L 12.5 - 25 umol/L Serum transferrin 2.440 g/L 1.8 - 3.2 g/L Percentage iron saturation 40.000 % 15 - 50 % Full blood count - FBC Haemoglobin estimation 134.000 g/L 120 - 160 g/L Total white cell count 4.900 10*9/L 4 - 11 10*9/L Platelet count 196.000 10*9/L 150 - 500 10*9/L Red blood cell (RBC) count 4.300 10*12/L 3.8 - 5.8 10*12/L Haematocrit 0.423 L/L 0.36 - 0.47 L/L Mean corpuscular volume (MCV) 98.300 fL 76 - 103 fL Mean corpusc. haemoglobin(MCH) 31.100 pg 27 - 32 pg Mean corpusc. Hb. conc. (MCHC) 317.000 g/L 300 - 360 g/L Red blood cell distribut width 12.700 %CV 11 - 16 %CV Percentage hypochromic cells 1.300 % 0 - 2.5 % Neutrophil count 3.140 10*9/L 1.5 - 8 10*9/L Lymphocyte count 1.180 10*9/L 1.3 - 4 10*9/L Monocyte count 0.340 10*9/L 0.2 - 0.8 10*9/L Eosinophil count 0.100 10*9/L 0 - 0.8 10*9/L Basophil count 0.050 10*9/L 0 - 0.3 10*9/L B12 AND FOLATES Serum vitamin B12 328.000 ng/L 211 - 911 ng/L Serum folate 8.390 ug/L 3.38 - 23.9 ug/L Serum total 25-OH vit D level 33.000 nmol/L 50 - 374 nmol/L Serum TSH level 4.080 mu/L 0.55 - 4.78 mu/L Serum ferritin 148.000 ug/L 10 - 291 ug/L

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MrsR14
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4 Replies
MrsR14 profile image
MrsR14

I've just realised it is 800 I.U. of Vit D not MG!!

marsaday profile image
marsaday

Go back down to 25mcg. Increases and raises of thyroid meds are part of the process.

Over time your body may be happier on an increase, but at the moment it doesn't like it.

Your Ft4 at 17 is in an ok place.

TSH is 4 so a little high. Better being around 1.

See how you feel back at 25mcg T4 and then try and increase again in a few weeks, but doing a 50 every third day.

T4 only may not be the full answer as well. You may need a little T3, but try work with the T4 for now.

Vitamin D is low and you may want to use 2 tablets of Vitamin D per day.

MrsR1412 profile image
MrsR1412 in reply tomarsaday

Thanks for your reply. I have got a combined vit d and calcium, worried about taking too much calcium if I take more of them. I will go and buy some more vitamin D and top it up.

silverfox7 profile image
silverfox7

Vit D will not go up on the dose you are taking. Search SeasideSusie's posts-lots of brilliant info on ranges and how to treat things properly. With Vit D you need a booster dose to get it higher. What you have been given is a very low maintenance dose. Look at the other things as well.

Sometimes we don't react well to thyroid meds if Vits etc are low so get them checked out and supplement. It takes time to reach the end product but worth it.

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