I have written 3 months ago about my son who is 19yrs old. I am still struggling to help him and the GPs are totally rubbish and negligent tbh!
I have since had his Cortisol and DHEA tested by Genova Diagnostics.
I am now trying (and struggling) to understand what to do next!
Sample 1 - Post Awakening - 47.40 High (7.45-32.56) - VERY HIGH
Sample 2 - late morning - 15.20 High (2.76-11.31) - SLLIGHTLY HIGH
Sample 3 - late afternoon - 19.00 High (1.38-7.45) - VERY HIGH
Sample 4 - late evening - 8.40 High (0.83-3.86) - SLIGHTLY HIGH
SUM OF CORTISOL = 90
DHEA - Mean - 1.12
DHEA - Cortisol Ratio - 0.033 - so in range (0.015-0.150)
TSH - 2.54 (0.27-4.20) Probably higher now coz not on Levo
Free T4 - High - 22.57 (12-22)
Free T3 5.82 (3.1-6.8)
Reverse T3 - 24 (10-24)
Anti-Throidperoxidase abs - 8.4 (<34)
Anti-Thyroglobulin abs - 18.7 (<115)
Vit D - 101
Vit B12 - 1017 (had been supplementing but stopped 4 months prior to this result so not sure how long it takes to come down - 1 year previously had been very low)
Serum folate - 32.12 (8.83-60.8)
Ferritin - 89.4 (30-400)
CRP - 0.10
His symptoms have worsened, particularly
• extreme brain fog to the point of having to defer his degree!
• From being a superb speller he is now having to check spelling of words regularly and this skill is definately being severely damaged.
• His social anxiety is worsening because he is fumbling for words more and more and now at a point where he is worried to open his mouth because it just embarrases him.
• Severe tiredness immediately after a meal at the table,
• Cannot walk far without feeling exhausted,
• Terrible Acne on face that won't budge
His Thyroid tests 3 months ago showed that taking Levothyroxine actually lowered the TSH, but highered his RT3 and also highered his T4 to absolute top of range.
I've researched and researched for both his health and mine for over 3 years, and really do feel totally overwhelmed with it all now! I'm crumbling under the pressure to try to help him because the doctors won't!
With regard to his Cortisol tests, I have found this link that gives guidance (from a post someone on this forum posted previously) but I still don't know how to best support him. rt3-adrenals.org/cortisol_t...
Here is one example that they give on that link which correlates with my sons results.
High levels at most or at all times
• Frequently a precursor to low levels
• From stress, internal and/or external
• Can be caused by systemic conditions such as
• long-term hypothyroid
• high glucose
• gastrointestinal issues
my comments relating to the above info:-
• so should I retest in a couple of months to see if it has all altered?
• Yes he has had stress related to his uni studies and now has had to defer it due to health issues not allowing him to concentrate and absorb the information
• Yes he has had TSH in region of 3-4 over last 2 years and GP won't do anything because he is at that 'hormonal age!' so she won't even think about helping him!!!
• He is not too bad with glucose, although does love his oats/cornflakes/granola and has 2 bowls a day along with a very healthy main meal per day with 6-8 fresh cooked veg and low carbs.
• gastro problems - YESSS! We are all gluten free, he is lactose free, and cannot tolerate ANY grains at all other than oats (so no rice/quinoa or other GF substitutes)
So could the Cortisol be causing a Thyroid issue, or the Thyroid be causing the Cortisol spikes!?
I have researched the B12 deficiency symptoms, which seem to correlate very accurately with his symptoms, but of course now that the B12 has come up to 1000 the GP does not see through that! (although it was 4 months without supplementation which confuses me too) My grandma had P.A. and my dad is looking possibly to have early signs)
I have started him on Holy Basil once a day.
He takes B-Right (B Complex with Folate), Vit D maintenance dose, Siberian Ginseng to help with anxiety/depression), Vit E, Vit B6.
He also takes a good Pro-biotic once a day and Digestive enzymes before each meal to help with digestion (burping, sleeping after main meal in evening)
I am trying him with a tablespoon of ACV or lemon juice in warm water before each meal to try to help the low Stomach acid that I THINK he has)
Please could anyone look through this all for me and let me know if I am missing anything obvious and also what to do about the High Cortisol test results?
Sorry that it is a very long post, just need to give you all the information to try to see through the fog!
The GP makes us both feel stupid for even mentioning his symptoms, because individually they COULD all be part of adolescence/hormones/anxiety etc, but will not look at them collectively. Especially the loss of English language spoken, reading and written, this is a major problem!!!)
Many thanks in advance for any glimmer of light that can be offered!