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New machine learning model could enable targeted gene therapies for genetic diseases
A cure is coming Johns Hopkins University biomedical engineers have developed a machine-learning model that could one day lead to therapies to treat genetic diseases like cancer and diabetes. The model can predict which enhancers play a role in normal development and disease, and can be used to identify
A cure is coming Johns Hopkins University biomedical engineers have developed a machine-learning model that could one day lead to therapies to treat genetic diseases like cancer and diabetes. The model can predict which enhancers play a role in normal development and disease, and can be used to identify
Scout4answers
in
Advanced Prostate Cancer
9 months ago
Constipation
Hi helpful community. I am on 40 mg or prednisone for CGA, tapering down to 35 in 2 days for 2 weeks. I am suffering from constipation. Is it due to the prednisone or the Calcium supplements (600 mg x 2 per day)? I take Miralax (Restorolax) every couple of days. then I take mineral oil for couple
Hi helpful community. I am on 40 mg or prednisone for CGA, tapering down to 35 in 2 days for 2 weeks. I am suffering from constipation. Is it due to the prednisone or the Calcium supplements (600 mg x 2 per day)? I take Miralax (Restorolax) every couple of days. then I take mineral oil for couple
Groda
in
PMRGCAuk
8 months ago
EMDR.. anyone?
I am due to start EMDR next week. I have put it off for quite some time for one reason or another but I finally feel brave enough to start this. Anyone else on this journey? Or any success stories? My therapist thinks I have lots of little traumas mostly including health and death and believes this will
I am due to start EMDR next week. I have put it off for quite some time for one reason or another but I finally feel brave enough to start this. Anyone else on this journey? Or any success stories? My therapist thinks I have lots of little traumas mostly including health and death and believes this will
Kimbad1990
in
Anxiety and Depression Support
4 months ago
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New MRI finding
Yesterday I had an MRI due to some back pain. I had an MRI, pet scan in February and clean CAT scan in June. Plus all of my labs have been perfect. Now they’re telling me that they see a 2.1 CM metastasis on my L2 area of my spine. I am a bit freaked out but I’m trying to wrap my head around this.
Yesterday I had an MRI due to some back pain. I had an MRI, pet scan in February and clean CAT scan in June. Plus all of my labs have been perfect. Now they’re telling me that they see a 2.1 CM metastasis on my L2 area of my spine. I am a bit freaked out but I’m trying to wrap my head around this.
Flavia100
in
SHARE Metastatic Breast Cancer
9 months ago
Radiation for Salvage Treatment
I am about to start salvage treatment after a failed surgery and a rising PSA value of 0.1. However, I would like to know if weeks of external radiation with ADT, is the best treatment option here. The idea of blindly radiating pelvic area with a re-recurrence a few years later does not appeal to me.
I am about to start salvage treatment after a failed surgery and a rising PSA value of 0.1. However, I would like to know if weeks of external radiation with ADT, is the best treatment option here. The idea of blindly radiating pelvic area with a re-recurrence a few years later does not appeal to me.
Rams91
in
Prostate Cancer Network
9 months ago
Pain won't stop
Hi all, it's been assumed that I'm struggling with IBS for around 6 weeks. I've tried buscopan forte with no ease. Last Friday I started Mebeverine hydrochloride 3 times a day, it's not helping! For 6 weeks I have pretty much been stuck in the fetal position with servere cramping pain that I'm comparing
Hi all, it's been assumed that I'm struggling with IBS for around 6 weeks. I've tried buscopan forte with no ease. Last Friday I started Mebeverine hydrochloride 3 times a day, it's not helping! For 6 weeks I have pretty much been stuck in the fetal position with servere cramping pain that I'm comparing
GracefulRaven
in
IBS Network
8 months ago
Decreasing iron levels despite taking iron
My new iron test shows it is now 14.5 umol/l (5.8 - 34.5) and on 4th September it was 17.7 umol/l (5.8 - 34.5). I have been taking iron drops every day (except for period of time before each blood test). Is this normal?
My new iron test shows it is now 14.5 umol/l (5.8 - 34.5) and on 4th September it was 17.7 umol/l (5.8 - 34.5). I have been taking iron drops every day (except for period of time before each blood test). Is this normal?
jenny876
in
Thyroid UK
8 months ago
IBS and possible prolapse in bowel
Hi all, I have been diagnosed with IBS and Diverticulitis. Pregablin medication seems to be helping. When I recently explained to the GP that every day I am in discomfort from my bowel and despite me having bowel movements on a daily basis that within 30-45 mins after I feel I need to have another bowel
Hi all, I have been diagnosed with IBS and Diverticulitis. Pregablin medication seems to be helping. When I recently explained to the GP that every day I am in discomfort from my bowel and despite me having bowel movements on a daily basis that within 30-45 mins after I feel I need to have another bowel
PinkCrayon123
in
IBS Network
8 months ago
EMDR therapy what is it and dose it help
I'm curious about EMDR therapy and if it's a direction I should go in?
I'm curious about EMDR therapy and if it's a direction I should go in?
LostNormality
in
Anxiety and Depression Support
3 months ago
Advice please
Hi there, my mum was diagnosed with HGSOC stage 4 in October 21. She had debulking surgery followed by 6 rounds of carbo/taxol. She recovered well and continued with Avastin infusions every 3 weeks until May this year when her CA125 started to gradually rise. Her CT scan at this time showed NED and they
Hi there, my mum was diagnosed with HGSOC stage 4 in October 21. She had debulking surgery followed by 6 rounds of carbo/taxol. She recovered well and continued with Avastin infusions every 3 weeks until May this year when her CA125 started to gradually rise. Her CT scan at this time showed NED and they
Pitchperfec
in
My Ovacome
9 months ago
LU-177 I&T, FAILURE?
Just received PSA results from 4th Infusion of LU-177 I&T, as part of the Eclipse Study. It increased from 0.1 to 0.2. PSA baseline was 2.0. Following 1st infusion PSA dropped to 0.3. Following 2nd infusion no PSA was taken. Following 3rd infusion PSA 0.1. Following 4th infusion PSA 0.2. Having
Just received PSA results from 4th Infusion of LU-177 I&T, as part of the Eclipse Study. It increased from 0.1 to 0.2. PSA baseline was 2.0. Following 1st infusion PSA dropped to 0.3. Following 2nd infusion no PSA was taken. Following 3rd infusion PSA 0.1. Following 4th infusion PSA 0.2. Having
john4803
in
Advanced Prostate Cancer
9 months ago
Lymphoma or unconnected New Tumour.
Hi All, further to my recent 'post' re the Bells Palsy' that never was, I want to thank you all for your support and advice. I am still waiting on a 'Biopsy' date, followed by the three week wait for results. After which I will know better, where I stand. I have received my recent Bloods from my
Hi All, further to my recent 'post' re the Bells Palsy' that never was, I want to thank you all for your support and advice. I am still waiting on a 'Biopsy' date, followed by the three week wait for results. After which I will know better, where I stand. I have received my recent Bloods from my
Vindicatrix
in
CLL Support
9 months ago
EBRT SE after Brachytherapy
Well, I can say the last 3 weeks after brachytherapy have been, medically, the worst of my entire life. QOL was poor at best. Maybe I have lived a sheltered life all these years and didn’t know what it is like to really be ill or have medical issues. I do now. Brachytherapy dose was 85 Gy, 60 seeds.
Well, I can say the last 3 weeks after brachytherapy have been, medically, the worst of my entire life. QOL was poor at best. Maybe I have lived a sheltered life all these years and didn’t know what it is like to really be ill or have medical issues. I do now. Brachytherapy dose was 85 Gy, 60 seeds.
electronics-guy
in
Prostate Cancer Network
9 months ago
Helperwifey
I am the wife of a husband who has advanced prostate cancer. He has just finished 6 rounds of Taxotere chemotherapy. He has taken Orgovyx and Nubeqa since his diagnosis. I am exploring holistic adjunctive therapy for him.
I am the wife of a husband who has advanced prostate cancer. He has just finished 6 rounds of Taxotere chemotherapy. He has taken Orgovyx and Nubeqa since his diagnosis. I am exploring holistic adjunctive therapy for him.
Helperwifey
in
Advanced Prostate Cancer
9 months ago
Any IBS type C constipation sufferers here ?
I was diagnosed 2 years ago with IBS constipation and I still don't know what triggers it and what does I have it constantly anything I eat makes me bloat so bad that I look heavily pregnant and it can stay like that for days I can go 4 to 5 days most of the time without being able to go to the toilet
I was diagnosed 2 years ago with IBS constipation and I still don't know what triggers it and what does I have it constantly anything I eat makes me bloat so bad that I look heavily pregnant and it can stay like that for days I can go 4 to 5 days most of the time without being able to go to the toilet
Worrier29
in
IBS Network
8 months ago
Dad actively dying , can't breathe. Horrifying. Need support after today if anyone available to reach out.
Seven year aggressive fight against stage four cancer from the start which after treatment turned to cll. His pca never changed but very slightly until of all meds and five weeks of hospice..chronic lymphocytic leukemia presumably from treatment is what's taking his life . "Gene's laughter and positive
Seven year aggressive fight against stage four cancer from the start which after treatment turned to cll. His pca never changed but very slightly until of all meds and five weeks of hospice..chronic lymphocytic leukemia presumably from treatment is what's taking his life . "Gene's laughter and positive
Daddyishealing
in
Advanced Prostate Cancer
9 months ago
sleep
I started Effexor about a month ago. My old antidepressant had really fizzled out and I like… or am learning how to like Effexor. I enjoy how it has helped me but the sleeping situation is a bit rough. I am literally pulled from a deep sleep into this weird feeling state…. In the beginning it was a
I started Effexor about a month ago. My old antidepressant had really fizzled out and I like… or am learning how to like Effexor. I enjoy how it has helped me but the sleeping situation is a bit rough. I am literally pulled from a deep sleep into this weird feeling state…. In the beginning it was a
Mskitty21
in
Anxiety and Depression Support
6 months ago
Folate levels
Hi I recently started SI twice a day thanks to the advice of the wonderful people here I recently had surgery and this seems to have thrown my B12 levels out of wack. My twitching has been moderate the past week which I put down to the extra B12 although I hoped it would settle down.Having the odd
Hi I recently started SI twice a day thanks to the advice of the wonderful people here I recently had surgery and this seems to have thrown my B12 levels out of wack. My twitching has been moderate the past week which I put down to the extra B12 although I hoped it would settle down.Having the odd
SKYROCKET123
in
Pernicious Anaemia Society
8 months ago
Do I have lupus?
Several years ago I was having a lot of joint pains in my legs and fevers. I was referred to haematology who then referred me on to infectious diseases. The consultant did blood tests and told me I had a positive ANA test and anti-Double stranded dna antibody test which was positive, he diagnosed me
Several years ago I was having a lot of joint pains in my legs and fevers. I was referred to haematology who then referred me on to infectious diseases. The consultant did blood tests and told me I had a positive ANA test and anti-Double stranded dna antibody test which was positive, he diagnosed me
Poppy-12345
in
LUPUS UK
7 months ago
idk what to do
I've had three medication changes in the past year and each time it helps for a time, and then I have panic attacks and I just spiral down to the point where I can't function. I was fighting through it at college for a while, but then it was just to bad and couldn't keep going to class or being around
I've had three medication changes in the past year and each time it helps for a time, and then I have panic attacks and I just spiral down to the point where I can't function. I was fighting through it at college for a while, but then it was just to bad and couldn't keep going to class or being around
copingwithcomedy
in
Anxiety and Depression Support
6 months ago
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