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My trajectory after a "vacation" and a new metastasis
My backgound briefly (full details in Profile): aggressive form, BRCA2 mutation, RP in 2017, then 39 sessions of radiation, and 3 yrs of Lupron. All at Smilow Cancer Hospital. As a result, my PSA was undetectable for 2.5 years, and in 9/21 I was put on a "vacation" from treatment. Then PSA started
My backgound briefly (full details in Profile): aggressive form, BRCA2 mutation, RP in 2017, then 39 sessions of radiation, and 3 yrs of Lupron. All at Smilow Cancer Hospital. As a result, my PSA was undetectable for 2.5 years, and in 9/21 I was put on a "vacation" from treatment. Then PSA started
Istomin
in
Advanced Prostate Cancer
8 months ago
radiation or no radiation
I Just updated my profile and am G-9 with PNI, IDC and lymphovascular invasion. Check 2 mutation as well but Decipher at .41. RP Dr V Patel march 2020 (T3b, negative margins and negative lymph nodes) and PSA undetectable until Sept 2023. Started at 0.021 and now Feb 22nd 2024 at 0.052. Seeing Dr
I Just updated my profile and am G-9 with PNI, IDC and lymphovascular invasion. Check 2 mutation as well but Decipher at .41. RP Dr V Patel march 2020 (T3b, negative margins and negative lymph nodes) and PSA undetectable until Sept 2023. Started at 0.021 and now Feb 22nd 2024 at 0.052. Seeing Dr
Peppertree602
in
Advanced Prostate Cancer
5 months ago
Early Results of Estrogen PATCH trial - 1
Here are some Early Results from the first year of the Transdermal Estrogen PATCH trial. References are available on their website at: http://patch.mrcctu.ucl.ac.uk. The cohort was men with High or Very High Risk prostate cancer. Stage T3 (73%) and Stage T4 (14%), baseline PSA = 35 ng/mL. The upper
Here are some Early Results from the first year of the Transdermal Estrogen PATCH trial. References are available on their website at: http://patch.mrcctu.ucl.ac.uk. The cohort was men with High or Very High Risk prostate cancer. Stage T3 (73%) and Stage T4 (14%), baseline PSA = 35 ng/mL. The upper
janebob99
in
Prostate Cancer Network
5 months ago
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Anti-proliferative effect of Cannabidiol in Prostate cancer cell PC3
More on CBD and prostate cancer Anti-proliferative effect of Cannabidiol in Prostate cancer cell PC3 is mediated by apoptotic cell death, NF?B activation, increased oxidative stress, and lower reduced glutathione status https://pubmed.ncbi.nlm.nih.gov/37796968/ Abstract Prostate cancer is
More on CBD and prostate cancer Anti-proliferative effect of Cannabidiol in Prostate cancer cell PC3 is mediated by apoptotic cell death, NF?B activation, increased oxidative stress, and lower reduced glutathione status https://pubmed.ncbi.nlm.nih.gov/37796968/ Abstract Prostate cancer is
NewPotatoCaboose
in
Advanced Prostate Cancer
10 months ago
question about going to Mayo
we have an appointment to see Dr Sartor at Mayo but my husband has read Dr Kwon helps refer patients out of the country for Actinium 225. We saw Dr Sartor when he was at Tulane. Will we be able to discuss Atinium w Dr Sartor or should we also try to see Dr Kwon? What’s the appropriate etiquette?
we have an appointment to see Dr Sartor at Mayo but my husband has read Dr Kwon helps refer patients out of the country for Actinium 225. We saw Dr Sartor when he was at Tulane. Will we be able to discuss Atinium w Dr Sartor or should we also try to see Dr Kwon? What’s the appropriate etiquette?
SuppWife
in
Advanced Prostate Cancer
5 months ago
Steroids and Radium 223
Hi Hopefully my husband will start Radium 223 in 4-6 weeks. He recently stopped abiraterone after 5 months as his PSA was doubling every month. While he was on abiraterone he was taking 2mgs of dexamethasone, although 1mg for the last month. He’s currently taking 6mgs of prednisilone but our question
Hi Hopefully my husband will start Radium 223 in 4-6 weeks. He recently stopped abiraterone after 5 months as his PSA was doubling every month. While he was on abiraterone he was taking 2mgs of dexamethasone, although 1mg for the last month. He’s currently taking 6mgs of prednisilone but our question
NLondon43
in
Advanced Prostate Cancer
8 months ago
Final Path Report After RALP (Dad - 74, G7- 4+3) , what’s next ?
Hi All, I had posted about a month ago about my dad with G7 - 4+ 3. We originally thought there were bone Mets but it just turned out to be another bone anomaly identified in the PSMA PET scan. We went ahead with RALP and have shared the final path report here. While the MRI showed no signs of
Hi All, I had posted about a month ago about my dad with G7 - 4+ 3. We originally thought there were bone Mets but it just turned out to be another bone anomaly identified in the PSMA PET scan. We went ahead with RALP and have shared the final path report here. While the MRI showed no signs of
EzioAudi7
in
Advanced Prostate Cancer
8 months ago
infusion Side Effects
good morning fellow warriors. My PSA continues to move up so my oncologist ordered 20 sessions of radiation. The radiation was a walk in the park compared to the 1030-1048 Zometa infused Wednesday morning. Holy cow ! Peed (a few dribbles) every half hour. Chills then sweats. Bone ache throughout and
good morning fellow warriors. My PSA continues to move up so my oncologist ordered 20 sessions of radiation. The radiation was a walk in the park compared to the 1030-1048 Zometa infused Wednesday morning. Holy cow ! Peed (a few dribbles) every half hour. Chills then sweats. Bone ache throughout and
3putt
in
Advanced Prostate Cancer
5 months ago
Detection of Small Cell Prostate Cancer
I understand Small Cell Prostate Cancer (SCPC) may produce less PSA. How do you detect SCPC? Is it detectable by PSMA PET/CT scan?
I understand Small Cell Prostate Cancer (SCPC) may produce less PSA. How do you detect SCPC? Is it detectable by PSMA PET/CT scan?
dac500
in
Advanced Prostate Cancer
8 months ago
prostap
Hi Has anyone else experienced severe kidney area pain one side (right) I’ve had this pain a few weeks now and never had it before. I’ve had one dose of prostap following on from zoladex. Could it be linked? Also general bad pain all over and just feeling not right somehow. Any thoughts?
Hi Has anyone else experienced severe kidney area pain one side (right) I’ve had this pain a few weeks now and never had it before. I’ve had one dose of prostap following on from zoladex. Could it be linked? Also general bad pain all over and just feeling not right somehow. Any thoughts?
MrsPaddingtonBear
in
Endometriosis UK
1 year ago
Combine standard care with alternative care
The University of Maryland reported two cases of terminated PCs by combining standard care treatment with an alternative treatment. By reducing the PSAs to less than 3, the clioquinol + zinc killed more cancer than testosterone could renew, therefore termination. My PSA in three months went from 58
The University of Maryland reported two cases of terminated PCs by combining standard care treatment with an alternative treatment. By reducing the PSAs to less than 3, the clioquinol + zinc killed more cancer than testosterone could renew, therefore termination. My PSA in three months went from 58
agnut
in
Fight Prostate Cancer
8 months ago
Vacation from Lupron/Zytiga - Temporary or Permanent!
I have been on ADT (Lupron/Zytiga) for 2.5 years. PSA and testosterone immeasurable currently. Looking to go on "vacation" from meds. History: Gleason 8/9 with a PSA of only 1.89 (on Finasteride). CT/Bone scan did not show any definite metastasis. PSMA PET showed "possible" metastasis in 4 spots
I have been on ADT (Lupron/Zytiga) for 2.5 years. PSA and testosterone immeasurable currently. Looking to go on "vacation" from meds. History: Gleason 8/9 with a PSA of only 1.89 (on Finasteride). CT/Bone scan did not show any definite metastasis. PSMA PET showed "possible" metastasis in 4 spots
groth12345
in
Advanced Prostate Cancer
9 months ago
Abiraterone side effect
After 12 doses of abirateron/prednisone I developed a rather severe cough. Even though this is one of the listed side effects of abiraterone my oncologist says that she has never heard of it happening before. Has anyone here ever had this experience and, if so, was there a remedy for the cough or an
After 12 doses of abirateron/prednisone I developed a rather severe cough. Even though this is one of the listed side effects of abiraterone my oncologist says that she has never heard of it happening before. Has anyone here ever had this experience and, if so, was there a remedy for the cough or an
GrantB47
in
Advanced Prostate Cancer
10 months ago
My brother has advanced Prostate Cancer
I'm here for my brother. He is 55 now. He has diagnosed when he was 54 with advanced prostate cancer that had metastasized to his pelvic bone. He started hormone therapy on October 2022 and then started chemotherapy for 6 sessions from November 2022 till March 2023 and started Nubeqa at the same time
I'm here for my brother. He is 55 now. He has diagnosed when he was 54 with advanced prostate cancer that had metastasized to his pelvic bone. He started hormone therapy on October 2022 and then started chemotherapy for 6 sessions from November 2022 till March 2023 and started Nubeqa at the same time
rasher1
in
Advanced Prostate Cancer
9 months ago
Starting Abiraterone and predniSONE
Tomorrow morning I take my first dose of Abiraterone (Zytiga) and predniSONE for metastatic castrate resistant prostate cancer. I don't know what kind of side effects I would get. I hope I would tolerate the treatment well. Reaching this stage of my cancer I reflect on my 12 year journey with prostate
Tomorrow morning I take my first dose of Abiraterone (Zytiga) and predniSONE for metastatic castrate resistant prostate cancer. I don't know what kind of side effects I would get. I hope I would tolerate the treatment well. Reaching this stage of my cancer I reflect on my 12 year journey with prostate
dac500
in
Advanced Prostate Cancer
9 months ago
Good news for mCRPC (hopefully), phase 2
And here we go: "mCRPC patients who have relapsed or are refractory to androgen receptor signalling inhibitors (ARSIs) such as apalutamide, darolutamide, abiraterone and enzalutamide are included in the study." https://www.clinicaltrialsarena.com/news/oncternal-patient-prostate-cancer/
And here we go: "mCRPC patients who have relapsed or are refractory to androgen receptor signalling inhibitors (ARSIs) such as apalutamide, darolutamide, abiraterone and enzalutamide are included in the study." https://www.clinicaltrialsarena.com/news/oncternal-patient-prostate-cancer/
Maxone73
in
Advanced Prostate Cancer
10 months ago
b12 levels
hi I’ve recently been feeling fatigued more tired than usual at work and a general feeling of being unwell. I had routine bloods done and my b12 level came back as 1260. I did receive a b12 injection 2 week before the blood test as my pharmacist recommended it to maybe help with my symptoms. Also I was
hi I’ve recently been feeling fatigued more tired than usual at work and a general feeling of being unwell. I had routine bloods done and my b12 level came back as 1260. I did receive a b12 injection 2 week before the blood test as my pharmacist recommended it to maybe help with my symptoms. Also I was
Sharkyboy
in
Pernicious Anaemia Society
1 year ago
PSA Doubling-Time
This plot shows the Cumulative Risk of Death from All-Causes for men with prostate cancer versus Time from Negative Bone Scan (without curative treatment). The different lines show the effect of different PSA doubling times (DT), ranging from DT 15 months. The lines are essentially straight lines
This plot shows the Cumulative Risk of Death from All-Causes for men with prostate cancer versus Time from Negative Bone Scan (without curative treatment). The different lines show the effect of different PSA doubling times (DT), ranging from DT 15 months. The lines are essentially straight lines
janebob99
in
Prostate Cancer Network
5 months ago
PSMA PET Scan Frequency?
Hello forum members. This is my first post but have learned so much here, thanks to the contributors on this site. My husband’s last and only PSMA PET scan was 1.5 years ago showing 6 mets in small bones after PSA consistently rose a year after radiation. The standard ADT treatment was prescribed
Hello forum members. This is my first post but have learned so much here, thanks to the contributors on this site. My husband’s last and only PSMA PET scan was 1.5 years ago showing 6 mets in small bones after PSA consistently rose a year after radiation. The standard ADT treatment was prescribed
EatLovePray
in
Advanced Prostate Cancer
5 months ago
PSMA pet scan negative
My PSA was 0.1 on july 17th and 0.3 on Oct 16th. PSMA scan was done on Nov 7th but was negative. Am I safe to assume there must be some prostate cancer cell present that are not showing up on the scan? I am meeting with my MO at Dana Farber next week Any suggestions moving forward? I appreciate the
My PSA was 0.1 on july 17th and 0.3 on Oct 16th. PSMA scan was done on Nov 7th but was negative. Am I safe to assume there must be some prostate cancer cell present that are not showing up on the scan? I am meeting with my MO at Dana Farber next week Any suggestions moving forward? I appreciate the
Rfs1975
in
Advanced Prostate Cancer
9 months ago
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