Good news for mCRPC (hopefully), phase 2 - Advanced Prostate...

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Good news for mCRPC (hopefully), phase 2

Maxone73 profile image
8 Replies

And here we go:

"mCRPC patients who have relapsed or are refractory to androgen receptor signalling inhibitors (ARSIs) such as apalutamide, darolutamide, abiraterone and enzalutamide are included in the study."

clinicaltrialsarena.com/new...

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Maxone73
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8 Replies
Mw921000000 profile image
Mw921000000

the great joy that I feel reading about another possible treatment for mCRPC is unexplainable 🙏🏻. We were just told about the DORA trial conducted at MSK which combines taxotere with RAD-223. There’s not much explained about it in the sites I’ve found about it, but I’ll link it in case you’re interested. It’s already in phase III.

clinicaltrials.gov/study/NC...

Maxone73 profile image
Maxone73 in reply toMw921000000

let's hope for the best....

by the end of the month we will know more about arx517 (I hate when they wait for a major international conference to make some data public but...that's how it is) and they will talk also about data from phase 1 of urologytimes.com/view/phase...

I would also bet on some other "new" approaches, like oncolytic viruses....

Tall_Allen profile image
Tall_Allen

Good luck! I hope AR degraders work.

Maxone73 profile image
Maxone73

I still don’t need them but I like to know my options

gsun profile image
gsun

Possibly another arrow in the quiver. It's a long way away.

j-o-h-n profile image
j-o-h-n

Let's hope for the best, and pray for hope....

Good Luck, Good Health and Good Humor.

j-o-h-n Sunday 10/08/2023 6:16 PM DST

My husband is entering an ARX517 trial. He is scheduled for all the prep scans 17th and 18th, and provided his scans meet the trial standards, he will start ARX517 shortly thereafter. I am hoping PSMA and GRPr (or another) targeted drug will be the future dual therapies to keep MCRPC in check. 🤗

Maxone73 profile image
Maxone73 in reply to

I truly hope that arx517 will do wonders, for him and also for us all! 🤗

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