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Radium223 has not been a success, is Enzalutamide a good next option?
Stage 4 PCA for last 3 years. Had 6 cycles of Chemo and then Abiraterone for 18+ months (PSA dropped to 0.2 then more recently rose to 58 in June '23 ). Abiraterone eventually stopped working and I was able to join Radium 223 trial. Completed 5 of 6 cycles of Radium 223, then elected to stop since
Stage 4 PCA for last 3 years. Had 6 cycles of Chemo and then Abiraterone for 18+ months (PSA dropped to 0.2 then more recently rose to 58 in June '23 ). Abiraterone eventually stopped working and I was able to join Radium 223 trial. Completed 5 of 6 cycles of Radium 223, then elected to stop since
Ronnie7C
in
Advanced Prostate Cancer
9 months ago
What category of Intermediate Risk Am I?
I am trying to make a decision regarding HT with RT. I am 78. I have CKD 3b, and a solitary kidney. I am 6.5 years in remission from UTUC kidney cancer. A number of papers indicate that HT could be detrimental to my kidney. Those with FIR PCa could avoid HT with little risk. The following is defined
I am trying to make a decision regarding HT with RT. I am 78. I have CKD 3b, and a solitary kidney. I am 6.5 years in remission from UTUC kidney cancer. A number of papers indicate that HT could be detrimental to my kidney. Those with FIR PCa could avoid HT with little risk. The following is defined
Nordman
in
Advanced Prostate Cancer
3 months ago
Clinical Trial Dallas UT Southwestern
Will begin a Pfizer starting on Monday. I will post more later as it goes. We are adding a drug to Xtandi to treat solid tumors. I have been on and off Xtandi a few times. I am chemo naive. In the past had a very heavy tumor load and received 3 rounds of Lu-177 from Ishita Sen, Fortis health in Delhi
Will begin a Pfizer starting on Monday. I will post more later as it goes. We are adding a drug to Xtandi to treat solid tumors. I have been on and off Xtandi a few times. I am chemo naive. In the past had a very heavy tumor load and received 3 rounds of Lu-177 from Ishita Sen, Fortis health in Delhi
pilot52
in
Advanced Prostate Cancer
7 months ago
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how long typically does it take from diagnosis to treatment?
Hello, my father was just diagnosed with advanced aggressive prostate cancer Gleason 9-10 (TBC). Bone scan and CT scan are next to check for spread (please God it hasn’t), but the scans are not for another 2.5 weeks! Then follow-up to discuss results a full week after that. Which seems insane that we
Hello, my father was just diagnosed with advanced aggressive prostate cancer Gleason 9-10 (TBC). Bone scan and CT scan are next to check for spread (please God it hasn’t), but the scans are not for another 2.5 weeks! Then follow-up to discuss results a full week after that. Which seems insane that we
LDC2024
in
Advanced Prostate Cancer
3 months ago
Psa is back
Well I made it to 27 months of upsa testing after my surgery and went from <0.01 to my first detectable of 0.01. Don’t know what this means but I guess the next few upsa tests will be telling. Maybe a lab variation maybe not.
Well I made it to 27 months of upsa testing after my surgery and went from <0.01 to my first detectable of 0.01. Don’t know what this means but I guess the next few upsa tests will be telling. Maybe a lab variation maybe not.
Blackholes
in
Advanced Prostate Cancer
3 months ago
My initial MRI and wait time for biopsy
Just got my MRI. PSA rising slowly for 3 years from 4.0 to 5.1. The MRI indicates a pi-Rad level 4 lesion 10 ml, well defined with no infiltration. Either base peripheral zone 11 to 12 o clock or transitional mid gland zone 11 to 12 o clock. Will get the location cleared up. I have an MRI fusion
Just got my MRI. PSA rising slowly for 3 years from 4.0 to 5.1. The MRI indicates a pi-Rad level 4 lesion 10 ml, well defined with no infiltration. Either base peripheral zone 11 to 12 o clock or transitional mid gland zone 11 to 12 o clock. Will get the location cleared up. I have an MRI fusion
jethrotullag
in
Prostate Cancer Network
3 months ago
Switch from Lupron/abi to Orgovyx/abi?
As I approaching my third 3 month shot of Lupron I wonder if Orgo might push out my time fence to MCRP more than Lupron, but I don't see anything on it. Lupron/abi dropped my PSA and TT very quickly so that is not an advantage, but the side effects are considered to be less - though my side effects
As I approaching my third 3 month shot of Lupron I wonder if Orgo might push out my time fence to MCRP more than Lupron, but I don't see anything on it. Lupron/abi dropped my PSA and TT very quickly so that is not an advantage, but the side effects are considered to be less - though my side effects
jackwfrench
in
Prostate Cancer Network
3 months ago
Keytruda - year 4
So I’m pretty much closing the book on my 4th year on Keytruda (pembroluzimab). I’ve recently completely my 33rd Pembro infusion. Keytruda was my Hail Mary after running through most other SOC. My PSA was rising while on chemo the second time when I found out I had the markers that made me eligible
So I’m pretty much closing the book on my 4th year on Keytruda (pembroluzimab). I’ve recently completely my 33rd Pembro infusion. Keytruda was my Hail Mary after running through most other SOC. My PSA was rising while on chemo the second time when I found out I had the markers that made me eligible
Chugach
in
Advanced Prostate Cancer
7 months ago
Prostap
can anyone advise please, I have had my second injection today and my stomach is swollen one side and is very painful, I Dont remember it being this bad the first time. Is this normal please??
can anyone advise please, I have had my second injection today and my stomach is swollen one side and is very painful, I Dont remember it being this bad the first time. Is this normal please??
Shelldob
in
Women's Health
1 year ago
paxlovid and abiraterone
there may already be posts like this, and If there are I’m sorry, I couldn’t find them! my dad is covid positive (first time!). I read on here in the past some of you said that you can’t take paxlovid with abiraterone? He is on that, flomax and lupron. I know it’s better to take paxlovid before it
there may already be posts like this, and If there are I’m sorry, I couldn’t find them! my dad is covid positive (first time!). I read on here in the past some of you said that you can’t take paxlovid with abiraterone? He is on that, flomax and lupron. I know it’s better to take paxlovid before it
Ptripp2
in
Advanced Prostate Cancer
9 months ago
Treatment decision made
Decided to go the treatment route, took me a while but AS is no good mentally, PSA has crept up from 4.2 to 5.1 in 18 months, awaiting appt date with oncologist.Presumably SBRT as per discussion when diagnosed in autumn '22, will be at Christies Manchester. Will keep folk posted. Removal of the offending
Decided to go the treatment route, took me a while but AS is no good mentally, PSA has crept up from 4.2 to 5.1 in 18 months, awaiting appt date with oncologist.Presumably SBRT as per discussion when diagnosed in autumn '22, will be at Christies Manchester. Will keep folk posted. Removal of the offending
pd63
in
Prostate Cancer Network
3 months ago
started treatment plan
recurrent Prostate cancer suspected as PSA climbs to .62. I had prostate removed in 2017 and PSA was non detectable for several years. received treatment plan from city of Hope. 6 months ADT (Orgovyx) daily pill. I’m 5 days into hormones. Meeting with radiation oncologist next week to determine when
recurrent Prostate cancer suspected as PSA climbs to .62. I had prostate removed in 2017 and PSA was non detectable for several years. received treatment plan from city of Hope. 6 months ADT (Orgovyx) daily pill. I’m 5 days into hormones. Meeting with radiation oncologist next week to determine when
Raflo
in
Advanced Prostate Cancer
9 months ago
hypertension due to Lupron and Zytega
I was diagnosed in 2018 psa 87 Gleason 9 3 Mets low burden invasion to Vesicles Imrt radiation that caused calcification damage to bladder neck that has been resolved by hbot . I’m still have frequent urination at nigh due to thickening of bladder wall. I use top doctor vascular surgeon at penn
I was diagnosed in 2018 psa 87 Gleason 9 3 Mets low burden invasion to Vesicles Imrt radiation that caused calcification damage to bladder neck that has been resolved by hbot . I’m still have frequent urination at nigh due to thickening of bladder wall. I use top doctor vascular surgeon at penn
fredyworks
in
Advanced Prostate Cancer
3 months ago
Long Journey
Hey Guys, I don’t post on here often and I’m afraid this will be a long post. I have had PCa over 18 years. Started with casodex, Lupron. A few months later, brachytherapy then 42 sessions of EBRT. Over the years PSA would rise, and I would be put on Lupron for 18-24 months. In 2017, PSA started rising
Hey Guys, I don’t post on here often and I’m afraid this will be a long post. I have had PCa over 18 years. Started with casodex, Lupron. A few months later, brachytherapy then 42 sessions of EBRT. Over the years PSA would rise, and I would be put on Lupron for 18-24 months. In 2017, PSA started rising
MJCA
in
Prostate Cancer And Gay Men
3 months ago
Dalidoman
Newly diagnosed stage 4 prostate cancer, age 77, PSA in low 20 range. PSMA (type of PET scan) revealed metastasis to 7 bone sites, with intermittent hip pain alleviated with Tylenol. Occasionally short of breath because, I think, below normal hemoglobin, platelet and iron levels consistent with bone
Newly diagnosed stage 4 prostate cancer, age 77, PSA in low 20 range. PSMA (type of PET scan) revealed metastasis to 7 bone sites, with intermittent hip pain alleviated with Tylenol. Occasionally short of breath because, I think, below normal hemoglobin, platelet and iron levels consistent with bone
DAR1890
in
Advanced Prostate Cancer
3 months ago
Abiraterone
Prostrate removed 2015, Savage radiation 2018, PSA went from 1.9 to 7.9 in 3 months in 2023 and bone scan and all tests show bone cancer including some lymph glands. Presently on Abiraterone and prendisone for the last 2 weeks and wonder if it works or not and looking for any comments or advise?
Prostrate removed 2015, Savage radiation 2018, PSA went from 1.9 to 7.9 in 3 months in 2023 and bone scan and all tests show bone cancer including some lymph glands. Presently on Abiraterone and prendisone for the last 2 weeks and wonder if it works or not and looking for any comments or advise?
RayKo
in
Men's Health Forum
7 months ago
Treatment going forward
Boyfriend is 73 was on AS after TRUS bx with decipher score 3.0. Bx 3+4 after downgrade from JH. Now one year later Saturation Biopsy reports 3+5=8 one core and 4+5=9 two cores between 5 and 20% pattern 5. PSA remains about 3.4. Total of 9/30 positive mostly 3+4=7 20% pattern 4. PSMA PET/CT reports
Boyfriend is 73 was on AS after TRUS bx with decipher score 3.0. Bx 3+4 after downgrade from JH. Now one year later Saturation Biopsy reports 3+5=8 one core and 4+5=9 two cores between 5 and 20% pattern 5. PSA remains about 3.4. Total of 9/30 positive mostly 3+4=7 20% pattern 4. PSMA PET/CT reports
good2go
in
Advanced Prostate Cancer
3 months ago
CT and Bone Scan 2 weeks after PSMA PET?
Note:
for reference, my dad lives in BC, Canada. I believe the system here is a bit different than the US - we have a urologist who refers us to the RO when needed. Therefore, there is no relationship between the urologist and RO - the RO is part of the cancer institute, but the urologist is not
Note:
for reference, my dad lives in BC, Canada. I believe the system here is a bit different than the US - we have a urologist who refers us to the RO when needed. Therefore, there is no relationship between the urologist and RO - the RO is part of the cancer institute, but the urologist is not
sixmongoos
in
Advanced Prostate Cancer
7 months ago
Fish consumption and PCa Mortality. A meta-analysis.
New study below. [1] "In total, 25 prospective cohort studies, recruiting 1,216,474 men, were included in the systematic review, and 22 studies were included in the meta-analysis. During the follow-up periods, ranging from 6 to 33 years, a total of 44,722 cases of prostate cancer were recorded."
New study below. [1] "In total, 25 prospective cohort studies, recruiting 1,216,474 men, were included in the systematic review, and 22 studies were included in the meta-analysis. During the follow-up periods, ranging from 6 to 33 years, a total of 44,722 cases of prostate cancer were recorded."
pca2004
in
Fight Prostate Cancer
9 months ago
Care at High-Volume Radiation Treatment Centers Tied to Higher Survival
Published in Oncology News · August 17, 2023 Care at High-Volume Radiation Treatment Centers Tied to Higher Survival Findings seen among men with very high-risk prostate cancer HealthDay WEDNESDAY, Aug. 16, 2023 (HealthDay News) -- Among men with very high-risk prostate cancer, higher radiation
Published in Oncology News · August 17, 2023 Care at High-Volume Radiation Treatment Centers Tied to Higher Survival Findings seen among men with very high-risk prostate cancer HealthDay WEDNESDAY, Aug. 16, 2023 (HealthDay News) -- Among men with very high-risk prostate cancer, higher radiation
Balsam01
in
Advanced Prostate Cancer
9 months ago
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