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PSA increase nearly one year after triplet therapy (mHSPC), what's next?
Hello everyone, thank you for all your help for a year. My dad went from a high of 3103 PSA to a nadir of 44. He unfortunately couldn't reach a <1 result but it had stabilized for a few months after his docetaxel + zytiga + prednisone. Unfortunately his new result is 67 PSA exactly a year since diagnosis
Hello everyone, thank you for all your help for a year. My dad went from a high of 3103 PSA to a nadir of 44. He unfortunately couldn't reach a <1 result but it had stabilized for a few months after his docetaxel + zytiga + prednisone. Unfortunately his new result is 67 PSA exactly a year since diagnosis
Sissel25
in
Advanced Prostate Cancer
7 months ago
My PSA tripled in 8 months
I had my RP in Jan 31, 2023, started hormonal therapy from April 17 with Diphereline every 28 days plus one Casodex daily. My PSA went down to 0.005 from May to November. Yesterday I had my blood test again and the report indicated my PSA has jumped to 0.159. I am panic. Can you explain what does
I had my RP in Jan 31, 2023, started hormonal therapy from April 17 with Diphereline every 28 days plus one Casodex daily. My PSA went down to 0.005 from May to November. Yesterday I had my blood test again and the report indicated my PSA has jumped to 0.159. I am panic. Can you explain what does
Formosan
in
Advanced Prostate Cancer
7 months ago
Just some good news
Just wanted to update you all on this in case anyone is thinking of surgery to fix something non-cancer related. My husband was looking into getting a hip replacement back in 2021 when he was diagnosed with PC. So the hip replacement was put on hold,. But the hip arthritis kept getting worse and he
Just wanted to update you all on this in case anyone is thinking of surgery to fix something non-cancer related. My husband was looking into getting a hip replacement back in 2021 when he was diagnosed with PC. So the hip replacement was put on hold,. But the hip arthritis kept getting worse and he
Bspouse
in
Advanced Prostate Cancer
3 months ago
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PSA analysis 6 months after radiation
In January I will be 6 months post radiation to the prostrate and complete pelvic area. I was on Lupron for 6 months - 1 month prior and 5 months post radiation. I also was on Casodex for one month prior to the start of Lupron to lessen the flare. At 3 months post radiation PSA and Testosterone were
In January I will be 6 months post radiation to the prostrate and complete pelvic area. I was on Lupron for 6 months - 1 month prior and 5 months post radiation. I also was on Casodex for one month prior to the start of Lupron to lessen the flare. At 3 months post radiation PSA and Testosterone were
Mgtd
in
Advanced Prostate Cancer
7 months ago
After Radiation, what should PSA be?
intermediate pc, with 3+4, 3+4, and 4+3. PSMA clean. Went through SBRT, am on Lupron. Seven months in. usual side effects, especially exhaustion. I went for a PSA and testosterone test today. Should my PSA be undetectable?
intermediate pc, with 3+4, 3+4, and 4+3. PSMA clean. Went through SBRT, am on Lupron. Seven months in. usual side effects, especially exhaustion. I went for a PSA and testosterone test today. Should my PSA be undetectable?
Photographerhere
in
Prostate Cancer Network
7 months ago
another undetectable
PSA in again at undetectable which I am assuming means my testosterone is not recovering . No T result yet but 0.5 last month! Still on Apalutamide as a monotherapy but coming off that too is bouncing around my head. Would love to go med free, still watching all developments and still no idea of the
PSA in again at undetectable which I am assuming means my testosterone is not recovering . No T result yet but 0.5 last month! Still on Apalutamide as a monotherapy but coming off that too is bouncing around my head. Would love to go med free, still watching all developments and still no idea of the
Brysonal
in
Fight Prostate Cancer
3 months ago
Prostate cancer radiotherapy side effects.
I’m a seventy seven year old who had a radical prostatectomy eight years ago. Following one of my regular PSA tests the result showed, after scans in September 2023, a return in the prostate bed and adjacent lymph nodes. Began hormone implants straight away followed by twenty doses of targeted radiotherapy
I’m a seventy seven year old who had a radical prostatectomy eight years ago. Following one of my regular PSA tests the result showed, after scans in September 2023, a return in the prostate bed and adjacent lymph nodes. Began hormone implants straight away followed by twenty doses of targeted radiotherapy
Gingerurgent
in
Pelvic Radiation Disease Association
3 months ago
Prostap (again!)
Hi, so i’m still suffering from the prostap injection but i’ve recently got an awful burning pain in my lower back, is this linked to the prostap? does anyone else get this? TIA x
Hi, so i’m still suffering from the prostap injection but i’ve recently got an awful burning pain in my lower back, is this linked to the prostap? does anyone else get this? TIA x
tamzx
in
Endometriosis UK
1 year ago
herbicide and recurrence
I'm looking for scientific evidence on herbicide exposure and cancer recurrence. Background: My condo association wants to spray my lawn with herbicide. (2-4-d & dicamba; thankfully not glyphosate--at least not yet) I've asked them not to and suggested safer alternatives. They say I'm being a PIA
I'm looking for scientific evidence on herbicide exposure and cancer recurrence. Background: My condo association wants to spray my lawn with herbicide. (2-4-d & dicamba; thankfully not glyphosate--at least not yet) I've asked them not to and suggested safer alternatives. They say I'm being a PIA
mistersafety
in
Advanced Prostate Cancer
3 months ago
salvage radiation after surgery?
Hi - Shouldn’t I be doing salvage radiation or chemotherapy now? I had my surgery February 25 and Doctor wants to wait for first PSA iat end of May. However surgical pathology showed negative margins but showed intraductal, cribriform, loss of PTEN. and PNI. Even though there was no EPE, no SVI, No LVI
Hi - Shouldn’t I be doing salvage radiation or chemotherapy now? I had my surgery February 25 and Doctor wants to wait for first PSA iat end of May. However surgical pathology showed negative margins but showed intraductal, cribriform, loss of PTEN. and PNI. Even though there was no EPE, no SVI, No LVI
Granolaberry
in
Prostate Cancer Network
3 months ago
husband with CRPC needing advice
Dearest fellow Warriors, I am new to the forum and appreciate reading your stories and advice. June 2009, my husband was diagnosed with Prostate Cancer with a PSA of 18 and Gleason 7 - Aug 2009, Radical Prostatectomy - PSA was .03 for two months, then began steadily rising - January 2012, 35 radiations
Dearest fellow Warriors, I am new to the forum and appreciate reading your stories and advice. June 2009, my husband was diagnosed with Prostate Cancer with a PSA of 18 and Gleason 7 - Aug 2009, Radical Prostatectomy - PSA was .03 for two months, then began steadily rising - January 2012, 35 radiations
Betsyhrd
in
Advanced Prostate Cancer
7 months ago
Cause for concern?
Would you please comment on the following article which may mean a new PET scan is required I'm my case? ( I Hope not!!) Extract from a recent article which is double Dutch to me!!! "...... Ignorant/lazy docs only take notice of the PSA, when it is widely known that at low PSA PSADT is equally, if not
Would you please comment on the following article which may mean a new PET scan is required I'm my case? ( I Hope not!!) Extract from a recent article which is double Dutch to me!!! "...... Ignorant/lazy docs only take notice of the PSA, when it is widely known that at low PSA PSADT is equally, if not
m1946
in
Prostate Cancer Network
3 months ago
Pluvicto+Xtandi Delays Progression Better than Xtandi-alone in mCRPC
Significant improvement in progression-free survival, PSA, and pain scores. Side effects were fatigue, nausea and dry mouth. https://www.prostatecancer.news/2024/04/pluvictoxtandi-delays-progression.html
Significant improvement in progression-free survival, PSA, and pain scores. Side effects were fatigue, nausea and dry mouth. https://www.prostatecancer.news/2024/04/pluvictoxtandi-delays-progression.html
Tall_Allen
in
Advanced Prostate Cancer
3 months ago
New hope for castrate resistant prostate cancer on the horizon
A new experimental drug is in development that reverses castrate resistance and makes the cancer amenable to further treatment. Early days yet but it looks interesting. https://www.theguardian.com/society/2023/oct/16/new-prostate-cancer-treatment-may-be-on-the-horizon-say-scientists
A new experimental drug is in development that reverses castrate resistance and makes the cancer amenable to further treatment. Early days yet but it looks interesting. https://www.theguardian.com/society/2023/oct/16/new-prostate-cancer-treatment-may-be-on-the-horizon-say-scientists
GeorgesCalvez
in
Advanced Prostate Cancer
9 months ago
The Science is Coming
Good to see the mini AZD5069 trial with enzalutamide offering another route to taming the beast. I am no scientist but as I understand it the target is myeloid white blood cells which can act to fuel tumours. The drup blocks the CXCR2 receptor and, in a small sample seems to have resulted in tumour shrinkage
Good to see the mini AZD5069 trial with enzalutamide offering another route to taming the beast. I am no scientist but as I understand it the target is myeloid white blood cells which can act to fuel tumours. The drup blocks the CXCR2 receptor and, in a small sample seems to have resulted in tumour shrinkage
GreenStreet
in
Prostate Cancer Network
9 months ago
FDG+/PSMA- lesions
My dad has metastatic CRPC. Xtandi failed, but at the moment he is still on it as we evaluate possible treatment options. Today we received also results of PSMA PET CT - it it stated, that there are discrepancies (loss of PSMA expression) with at least 4 bone mets when compared to findings of FDG (
My dad has metastatic CRPC. Xtandi failed, but at the moment he is still on it as we evaluate possible treatment options. Today we received also results of PSMA PET CT - it it stated, that there are discrepancies (loss of PSMA expression) with at least 4 bone mets when compared to findings of FDG (
MyDad76
in
Advanced Prostate Cancer
9 months ago
Hello again.
Diagnosed in February 2021 with a PSA of 37and prescribed a 2 year course of
Prostap
by
3
monthly injections. this had the effect of immediately lowering PSA to negligible. This was very quickly followed by a course of Aberaterone {Zytiga} which I was able to tolerate for about 10 months.
Diagnosed in February 2021 with a PSA of 37and prescribed a 2 year course of
Prostap
by
3
monthly injections. this had the effect of immediately lowering PSA to negligible. This was very quickly followed by a course of Aberaterone {Zytiga} which I was able to tolerate for about 10 months.
Hidden
in
Advanced Prostate Cancer
1 year ago
QoLing on a Prayer - a year later & PSA update
https://youtu.be/oabJ6vvz0OI?si=0gy0804F3Yqkp30s It's been a year since the 14th of 28s IMRT and the PSA is https://youtu.be/J2VDEl18rgQ?si=396vEID1xVZAw8S2 and at 1.3 the last two tests 😁, the lowest in 5 years -Woo Hoo For anyone who missed the vid, here ya go: https://photos.app.goo.gl/NkXaWGSHiNYNmvM57
https://youtu.be/oabJ6vvz0OI?si=0gy0804F3Yqkp30s It's been a year since the 14th of 28s IMRT and the PSA is https://youtu.be/J2VDEl18rgQ?si=396vEID1xVZAw8S2 and at 1.3 the last two tests 😁, the lowest in 5 years -Woo Hoo For anyone who missed the vid, here ya go: https://photos.app.goo.gl/NkXaWGSHiNYNmvM57
dockam
in
Advanced Prostate Cancer
3 months ago
R223 - PSA 26 Doubled since February
My husband has had 3 treatments of R223, had to postpone 4th treatment because of flu. On Monday had bloods taken in preparation of 4th treatment on 18th April 2024. Blood results ALP 76, at started of R223 106, HB 92 down from 102, (has Proctitis and occasional bleed, calcium a little low, taken
My husband has had 3 treatments of R223, had to postpone 4th treatment because of flu. On Monday had bloods taken in preparation of 4th treatment on 18th April 2024. Blood results ALP 76, at started of R223 106, HB 92 down from 102, (has Proctitis and occasional bleed, calcium a little low, taken
Janhpr
in
Advanced Prostate Cancer
3 months ago
my life is miserable life due to hormone treatment (eligard) want to quit asap . questions to ask ? /experiences ?
Im a very active 61 - had zero symptoms - no peeing in the night etc and 15 PSA was only flagged while doing pre op for a hip replacement in January. Next PSA was 17 in March so in for biopsy - 8 positive biopsy samples of 48 taken but only one of concern with Gleason of 8. PET scan indicated borderline
Im a very active 61 - had zero symptoms - no peeing in the night etc and 15 PSA was only flagged while doing pre op for a hip replacement in January. Next PSA was 17 in March so in for biopsy - 8 positive biopsy samples of 48 taken but only one of concern with Gleason of 8. PET scan indicated borderline
moon1878
in
Prostate Cancer Network
7 months ago
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