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Dad with Advanced PCA :(
Hi everyone, I am new here and appreciate any assistance that could help my father. My dad is 73 years of age. Over the last few weeks we have gone from a raised PSA level 8.9 (up from 6 in 2022 and 2021, 5.1 in 2020), Negative DRE, to an MRI (PIRADS 5, SAG T2) to a positive biopsy (10 cores taken,
Hi everyone, I am new here and appreciate any assistance that could help my father. My dad is 73 years of age. Over the last few weeks we have gone from a raised PSA level 8.9 (up from 6 in 2022 and 2021, 5.1 in 2020), Negative DRE, to an MRI (PIRADS 5, SAG T2) to a positive biopsy (10 cores taken,
MissMel2024
in
Advanced Prostate Cancer
3 months ago
Heights Smart Supplement - should I stop? Advice
Hi guys, After recently finding out I have Hashimotos (going to the Dr on Thursday) I have been taking stock on what I take and whether it is beneficial to me or could cause harm. I take the Heights Smart Supplement and wondered what you guys thought of what is inside it. I was mainly worried because
Hi guys, After recently finding out I have Hashimotos (going to the Dr on Thursday) I have been taking stock on what I take and whether it is beneficial to me or could cause harm. I take the Heights Smart Supplement and wondered what you guys thought of what is inside it. I was mainly worried because
Griffo_
in
Thyroid UK
1 year ago
Enlarged Lymph Nodes on MRI and CT
Hello, new to this. Never posted before, hoping for some insight. Gleason 7 (4+3) PSA 6. Bone scan clear but lymphadenopathy in groin nodes (inguinal; iliac nodes). Does this mean spread? Being sent for a PET Scan Friday.
Hello, new to this. Never posted before, hoping for some insight. Gleason 7 (4+3) PSA 6. Bone scan clear but lymphadenopathy in groin nodes (inguinal; iliac nodes). Does this mean spread? Being sent for a PET Scan Friday.
Blue1320
in
Prostate Cancer Network
3 months ago
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Tripple therapy - ADT+Lynparza+Xtandi
I just started Lynparza in addition to Xtandi and Loupron. I don’t have a BRCA mutation, but I was told that Lynparza may be beneficial regardless. I finished cycle of Jevtana (7 infusions) and Xtandi. My PSA was 0.74, but now it has increased to 2.3. All other tretments and history are in my bio. The
I just started Lynparza in addition to Xtandi and Loupron. I don’t have a BRCA mutation, but I was told that Lynparza may be beneficial regardless. I finished cycle of Jevtana (7 infusions) and Xtandi. My PSA was 0.74, but now it has increased to 2.3. All other tretments and history are in my bio. The
venecia1983
in
Advanced Prostate Cancer
3 months ago
EMBARK Trial: Combination-therapy is better.
This chart compares the risk of developing metastasis from prostate cancer, after 5 years from curative treatment, between three different arms of the EMBARK study (published in 2023): (1) Lupron monotherapy; (2) Enzalutamide monotherapy; and (3) Enzalutamide + Lupron combination therapy. The cohort
This chart compares the risk of developing metastasis from prostate cancer, after 5 years from curative treatment, between three different arms of the EMBARK study (published in 2023): (1) Lupron monotherapy; (2) Enzalutamide monotherapy; and (3) Enzalutamide + Lupron combination therapy. The cohort
janebob99
in
Prostate Cancer Network
3 months ago
3 Abiraterone tabs in place of 4.
Warriors Some time back I posted that my MO had told me to take 3 Abiraterone tablets with 5 mg Prednisone daily instead of 4 to help with an out of control Blood Pressure problem. I was worried (as were some of the responses) that this could impact the ADT therapy. Recently had blood work done
Warriors Some time back I posted that my MO had told me to take 3 Abiraterone tablets with 5 mg Prednisone daily instead of 4 to help with an out of control Blood Pressure problem. I was worried (as were some of the responses) that this could impact the ADT therapy. Recently had blood work done
85236442968
in
Advanced Prostate Cancer
3 months ago
Anti-Androgen Therapy and Bone Tumors in Prostate Cancer
Sorry guys, but I found this and all I can say is it scared the hell out of me. Now I don't know what to think. Maybe someone can sort it out. https://journals.lww.com/oncology-times/fulltext/2021/08050/anti_androgen_therapy_can_fuel_spread_of_bone.16.aspx Jeff Dunn AO, Professor and CEO of the Prostate
Sorry guys, but I found this and all I can say is it scared the hell out of me. Now I don't know what to think. Maybe someone can sort it out. https://journals.lww.com/oncology-times/fulltext/2021/08050/anti_androgen_therapy_can_fuel_spread_of_bone.16.aspx Jeff Dunn AO, Professor and CEO of the Prostate
85745
in
Advanced Prostate Cancer
6 months ago
Timing of Docetaxel
Hello. Am now in year 10. Details in profile. For 2+ years have been taking Zoladex, Zytiga and Prednisolone. The CT bone scans and Nuclear medicine full body scans every 6 months show no radiographic progression and I feel ok, apart from fatigue when not active. Recently have some discomfort
Hello. Am now in year 10. Details in profile. For 2+ years have been taking Zoladex, Zytiga and Prednisolone. The CT bone scans and Nuclear medicine full body scans every 6 months show no radiographic progression and I feel ok, apart from fatigue when not active. Recently have some discomfort
Ian99
in
Advanced Prostate Cancer
3 months ago
10-year update still shows no benefit to ART vs early SRT
ART
= adjuvant radiation therapy, within 6 months after radical prostatectomy (RP)
early SRT
= salvage radiation therapy, after PSA ≥ 0.1ng/ml or 3 consecutive rises. Median was 0.2 ng/ml. Median 1 ½ years after RP. Patients risked nothing by waiting, and gained urinary and fecal continence
ART
= adjuvant radiation therapy, within 6 months after radical prostatectomy (RP)
early SRT
= salvage radiation therapy, after PSA ≥ 0.1ng/ml or 3 consecutive rises. Median was 0.2 ng/ml. Median 1 ½ years after RP. Patients risked nothing by waiting, and gained urinary and fecal continence
Tall_Allen
in
Advanced Prostate Cancer
3 months ago
ASCO 2023: AI-Derived Digital Pathology Biomarker Predicts Benefit of Long-Term ADT with Radiotherapy in Localized High-Risk Prostate Cancer
https://www.urotoday.com/conference-highlights/asco-2023/asco-2023-prostate-cancer/144902-asco-2023-development-and-validation-of-an-ai-derived-digital-pathology-based-biomarker-to-predict-benefit-of-long-term-androgen-deprivation-therapy-with-radiotherapy-in-men-with-localized-high-risk-prostate-cancer-across-multiple-phase-iii-nrg-rtog-trials.html
https://www.urotoday.com/conference-highlights/asco-2023/asco-2023-prostate-cancer/144902-asco-2023-development-and-validation-of-an-ai-derived-digital-pathology-based-biomarker-to-predict-benefit-of-long-term-androgen-deprivation-therapy-with-radiotherapy-in-men-with-localized-high-risk-prostate-cancer-across-multiple-phase-iii-nrg-rtog-trials.html
zeitgeistxx
in
Advanced Prostate Cancer
6 months ago
BILLY NEEDS HELP
OK troops, after 26 years of surviving post prostectomy, with a Gleason 4/3, 4/4, some 41 rounds of intermittent hormone therapy using lupron, casadex, advodart, I had a break thru last November as my psa went back up mid on cycle. After having my radiation oncologist ignore the realities of this, I
OK troops, after 26 years of surviving post prostectomy, with a Gleason 4/3, 4/4, some 41 rounds of intermittent hormone therapy using lupron, casadex, advodart, I had a break thru last November as my psa went back up mid on cycle. After having my radiation oncologist ignore the realities of this, I
billyboy3
in
Advanced Prostate Cancer
3 months ago
how to reduce chemo side effects
I will be starting chemo for my prostate cancer in the next few weeks. Any suggestions as to cooling hats, gloves, and/or socks or other ways to reduce the side effects of chemo. What has been your experience with chemo side effects or your endeavors to reduce them? I expect I will be getting a regimen
I will be starting chemo for my prostate cancer in the next few weeks. Any suggestions as to cooling hats, gloves, and/or socks or other ways to reduce the side effects of chemo. What has been your experience with chemo side effects or your endeavors to reduce them? I expect I will be getting a regimen
shipoo
in
Advanced Prostate Cancer
6 months ago
prostap injections and alchol
hi does being on prostap injections make alcohol effect you more than it normally would please
hi does being on prostap injections make alcohol effect you more than it normally would please
Prettythings1
in
Endometriosis UK
10 months ago
PSA Rising After PBRT
Underwent prostate bed radiation in 2022 with good results — about a year of PSA at .02 to .05 — past six months, .09 and now at .17 Will get a PSMA-PET, but am curious what’s next ??
Underwent prostate bed radiation in 2022 with good results — about a year of PSA at .02 to .05 — past six months, .09 and now at .17 Will get a PSMA-PET, but am curious what’s next ??
FLRichardson
in
Advanced Prostate Cancer
3 months ago
Good News! Pluvicto Update
Hey Guys, I just had my third round of Pluvicto this last Tuesday. I had bloodwork done last week. The news seems promising: On 28 January (after docetaxel, but before Pluvicto), my PSA was 36.2. After 2 rounds of Pluvicto on 8 April, my PSA had dropped to 14.5! So, I am remaining positive! I have
Hey Guys, I just had my third round of Pluvicto this last Tuesday. I had bloodwork done last week. The news seems promising: On 28 January (after docetaxel, but before Pluvicto), my PSA was 36.2. After 2 rounds of Pluvicto on 8 April, my PSA had dropped to 14.5! So, I am remaining positive! I have
MJCA
in
Advanced Prostate Cancer
3 months ago
How do you know if radiation treatment worked?
I had 25 sessions of radiation to prostate and pelvic area as a precaution and 6 (2 months prior and 4 after radiation)months of Lupron. For 9 months post radiation PSA has been not been detectable and it has now risen to 0.04. T is in the normal range. All other blood works were normal. Meet with
I had 25 sessions of radiation to prostate and pelvic area as a precaution and 6 (2 months prior and 4 after radiation)months of Lupron. For 9 months post radiation PSA has been not been detectable and it has now risen to 0.04. T is in the normal range. All other blood works were normal. Meet with
Mgtd
in
Advanced Prostate Cancer
3 months ago
Earlier surrogates of overall survival to speed up new drugs development
there are statisticians (using AI) that are trying to find even earlier predictors to speed up the progress but it seems that progression free survival could already save 2 years for a new drug to be available on the market https://www.pcf.org/news/new-prostate-cancer-foundation-funded-research-to-speed-up-prostate-cancer-clinical-trials-worldwide
there are statisticians (using AI) that are trying to find even earlier predictors to speed up the progress but it seems that progression free survival could already save 2 years for a new drug to be available on the market https://www.pcf.org/news/new-prostate-cancer-foundation-funded-research-to-speed-up-prostate-cancer-clinical-trials-worldwide
Maxone73
in
Advanced Prostate Cancer
6 months ago
blood test to identify neuroendocrine cancer asap
ok I repost this mainly because the University of Trento is one hour from here and I got good friends there (working on CRISPR)…together with Dana-Farber they have developed a blood test to identify if there is an endocrine prostate cancer and the subtype https://medriva.com/cancer/a-breakthrough-in-prostate-cancer-treatment-new-blood-test-identifies-neuroendocrine-subtype
ok I repost this mainly because the University of Trento is one hour from here and I got good friends there (working on CRISPR)…together with Dana-Farber they have developed a blood test to identify if there is an endocrine prostate cancer and the subtype https://medriva.com/cancer/a-breakthrough-in-prostate-cancer-treatment-new-blood-test-identifies-neuroendocrine-subtype
Maxone73
in
Advanced Prostate Cancer
6 months ago
Mr Basil Charles
I was diagnosed with mestatic prostate cancer, PSA 29.1Spread to lymph node & bones in rib and spine My treatment plan 4 Abiraterone tablets 250gm & 1 Prednisone daily With a hormonal injection and bone strengthening drip quarterly After 2 years PSA dropped to 0.06 now it's 10.2 Lutetium 177 was
I was diagnosed with mestatic prostate cancer, PSA 29.1Spread to lymph node & bones in rib and spine My treatment plan 4 Abiraterone tablets 250gm & 1 Prednisone daily With a hormonal injection and bone strengthening drip quarterly After 2 years PSA dropped to 0.06 now it's 10.2 Lutetium 177 was
154Eleventh
in
Advanced Prostate Cancer
5 months ago
Need advice on clinical trial RO7656594
I have updated our profile, but in a nutshell we've gone through abiraterone, Xtandi, docetaxel, Pluvicto , cabazitaxel and carboplatin. My husband's most recent PSA on 4/12 was 79.52. His MO has put a hold on chemo our last 3 appointments due to pancytopenia. He's received 2 blood transfusions on his
I have updated our profile, but in a nutshell we've gone through abiraterone, Xtandi, docetaxel, Pluvicto , cabazitaxel and carboplatin. My husband's most recent PSA on 4/12 was 79.52. His MO has put a hold on chemo our last 3 appointments due to pancytopenia. He's received 2 blood transfusions on his
Yadifan
in
Advanced Prostate Cancer
3 months ago
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