10-year update still shows no benefit to ART vs early SRT

[Tall_Allen]

ART= adjuvant radiation therapy, within 6 months after radical prostatectomy (RP)

early SRT= salvage radiation therapy, after PSA ≥ 0.1ng/ml or 3 consecutive rises. Median was 0.2 ng/ml. Median 1 ½ years after RP.

Patients risked nothing by waiting, and gained urinary and fecal continence.

prostatecancer.news/2019/09...

annalsofoncology.org/articl...

[street-air]

thanks for posting this it is an interesting update. For the men in the adjuvant arm there were significantly more urinary and bowel issues that have so far not brought those people any better freedom from distant metastasis metrics. It is also interesting to see the salvage therapies were 95% to prostate bed. It seems like the best tool (psma pet) to discover where the actual recurrence is (lymph or bone vs bed) is not within reach as the salvage starts at 0.1 psa.

[Tall_Allen in reply to street-air]

Unfortunately, PSMA-detection is very PSA dependent. It doesn't detect much before PSA reaches 0.5 (unless PSADT is rapid). One has to treat before one can image metastases.

[Seasid]

Good to know. Thanks.

[Kaliber]

thanks for posting big guy.

👍👍👍

[Boywonder56]

fecal continence from the annals of onc.....just having fun t.a.........appreciate ya....

[j-o-h-n in reply to Boywonder56]

BTW I was just wondering if you're related to Stevie?

Good Luck, Good Health and Good Humor.

j-o-h-n

[dublin1717]

thanks TA good to know!