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ASCO 2014: Dr. Susan O'Brien Speculates on Combinations with Ibrutinib to Get a Complete Remission in CLL (chronic lymphocytic leukemia)
Friends, In this audio post on my blog, ( http://bkoffman.blogspot.com ) Dr. O'Brien gives some very informed speculation on what combination therapies with ibrutinib might be helpful in the future. She is very good at separating out what is known, and what is thought to be, but not yet proven. Brian
Friends, In this audio post on my blog, ( http://bkoffman.blogspot.com ) Dr. O'Brien gives some very informed speculation on what combination therapies with ibrutinib might be helpful in the future. She is very good at separating out what is known, and what is thought to be, but not yet proven. Brian
bkoffman
CLL CURE Hero
in
CLL Support
10 years ago
Blood work
Two years for now -it shows- a) Albumin- 41.9 g/L b)Alpha -1 Globulin 2.7 g/L c)Alpha -2 Globulin 7.7 g/L d)Beta 1 Globulin 4.5 g/L e)Beta 2 Globulin 5.2 g/L MARKED HIGH f)Gama Globulin 11.9 g/L ANA SCREEN --1:80=== NEGATIVE IMMUNOGLOBULIN A=3.97 g/L, G=11.57g/L,, M= 0.38 g/L (Marked H) C4= 0.43
Two years for now -it shows- a) Albumin- 41.9 g/L b)Alpha -1 Globulin 2.7 g/L c)Alpha -2 Globulin 7.7 g/L d)Beta 1 Globulin 4.5 g/L e)Beta 2 Globulin 5.2 g/L MARKED HIGH f)Gama Globulin 11.9 g/L ANA SCREEN --1:80=== NEGATIVE IMMUNOGLOBULIN A=3.97 g/L, G=11.57g/L,, M= 0.38 g/L (Marked H) C4= 0.43
KKA2014
in
CLL Support
10 years ago
Phyllocontin causing a big problem!!!!
Has anybody been prescribed phyllocontin continus 225 mg prolonged release tablets Aminophylline Hydrate? I was given these tablets at the end of August this year and was told they would help keep my lungs open. I was told to take 2 in the am. and 2 in the pm I was only taking one in the am. and
Has anybody been prescribed phyllocontin continus 225 mg prolonged release tablets Aminophylline Hydrate? I was given these tablets at the end of August this year and was told they would help keep my lungs open. I was told to take 2 in the am. and 2 in the pm I was only taking one in the am. and
mogworth
in
Lung Conditions Community Forum
10 years ago
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big toe swelling
I have E.T. and my big toe is red on the back side and has swelling. I have had this for months. My hematologist says it looks like gout and see a podiatrist if gets worse. It was painful in the beginning but not much pain now. Have read where toe problems are common with MPNs. Anyone else have
I have E.T. and my big toe is red on the back side and has swelling. I have had this for months. My hematologist says it looks like gout and see a podiatrist if gets worse. It was painful in the beginning but not much pain now. Have read where toe problems are common with MPNs. Anyone else have
marleque
in
MPN Voice
10 years ago
Low platelets
Don't know if my last post went through my platelets have been going down in the last few years just had a blood test they had dropped again to 109 does anyone else have this problem ???
Don't know if my last post went through my platelets have been going down in the last few years just had a blood test they had dropped again to 109 does anyone else have this problem ???
Angela
in
Thyroid UK
10 years ago
Thyroid binding globulin
When is it worth testing for Thyroid binding globulin (note: Not thyroglobulin). I am wondering if this could be implicated in why I cant seem to respond to a high dose of T3.
When is it worth testing for Thyroid binding globulin (note: Not thyroglobulin). I am wondering if this could be implicated in why I cant seem to respond to a high dose of T3.
suzannai
in
Thyroid UK
10 years ago
Flow symmetry
now I'm even more confused & I don't see the Hemayolgist until mid-Aug. I went online & found out some test results from the new Hematologist who redid everything (blood work): 1) beta 2 is high 2) "CD38 expression is dim heterogeneous. ABNORMAL CELL IMMUNOPHENOTYPE: (+) CD5, CD19, dim CD20, CD23
now I'm even more confused & I don't see the Hemayolgist until mid-Aug. I went online & found out some test results from the new Hematologist who redid everything (blood work): 1) beta 2 is high 2) "CD38 expression is dim heterogeneous. ABNORMAL CELL IMMUNOPHENOTYPE: (+) CD5, CD19, dim CD20, CD23
rlyndecker
in
CLL Support
10 years ago
Who do you talk to when you feel very down?
I feel like I haven't been allowed to be honest to anyone about how very down I feel. Being ambivolent about accepting renal replacement therapy has led to wild accusations from doctors - that I am begging for money, manipulative. They don't seem to get it - some of us have been so bullied by bad partners
I feel like I haven't been allowed to be honest to anyone about how very down I feel. Being ambivolent about accepting renal replacement therapy has led to wild accusations from doctors - that I am begging for money, manipulative. They don't seem to get it - some of us have been so bullied by bad partners
lizzy50
in
Dialysis Support
10 years ago
Has anyone heard of having severe nose bleeds from stopping B-12 shots after 15 years.
I have just have a very painful procedure to stop severe nose bleed. Had several in back 6 weeks so ENT decided to try embolization bilateral Sphenopalatine arteries. I will not know if it worked until next week when packing is removed. No one seems to know why this happened. I did stop taking the
I have just have a very painful procedure to stop severe nose bleed. Had several in back 6 weeks so ENT decided to try embolization bilateral Sphenopalatine arteries. I will not know if it worked until next week when packing is removed. No one seems to know why this happened. I did stop taking the
southernlady18
in
Fibromyalgia Action UK
10 years ago
Is Galvus met 50/500 harmful
I am insulin dependent diabities patient my doctor has advised to take Galvus met 50/500 is it safe drug a k sachan
I am insulin dependent diabities patient my doctor has advised to take Galvus met 50/500 is it safe drug a k sachan
sachanak
in
Diabetes India
10 years ago
Gout and SOB is there a link?
I have rare bouts of gout but every time it flairs up my lungs get gooey. I am peaking at 90% O2 at rest. I am also having more Sleep apnoea episodes Anyone else have this happen? Or is my lungs causing the Gout? Be Well
I have rare bouts of gout but every time it flairs up my lungs get gooey. I am peaking at 90% O2 at rest. I am also having more Sleep apnoea episodes Anyone else have this happen? Or is my lungs causing the Gout? Be Well
Offcut
in
Lung Conditions Community Forum
10 years ago
I'm struggling for some time feeling most uncomfortable condition after I take the medicine viz. Syncapone 150 -(this is the combination
of Carbidopa, Levodopa and Entacapone tablets). For a while I can't make out which is going on in my brain. Even I can't understand. I get scared! My Neurologist could not give satisfactory explanation. I continue to suffer. I think I should stop the medication and go for Natural Ayurvedic medicines
of Carbidopa, Levodopa and Entacapone tablets). For a while I can't make out which is going on in my brain. Even I can't understand. I get scared! My Neurologist could not give satisfactory explanation. I continue to suffer. I think I should stop the medication and go for Natural Ayurvedic medicines
cgamin
in
Cure Parkinson's
10 years ago
Pain symptomatic of Gout in foot for last 10 days, given Naproxen, completed dose but pain worse than ever, have ET, I'm on HU and aspirin.
Working in Khazakstan, health care difficult, what can I safely take to ease pain?
Working in Khazakstan, health care difficult, what can I safely take to ease pain?
Flaxy
in
MPN Voice
10 years ago
god grant me the senility to forget the people i never liked, the good fortune to remember the ones i do,and the eyesight to tell the differ
ence:) now that im older , heres what ive discovered: [1] i started with nothing,, and still have most of it. [2]my "wild oats" are mostly enjoyed with prunes and all-bran [3] i finally got my head together,,,and now my bodies falling apart [3] funny,,,i dont remember being absent minded [5] funny
ence:) now that im older , heres what ive discovered: [1] i started with nothing,, and still have most of it. [2]my "wild oats" are mostly enjoyed with prunes and all-bran [3] i finally got my head together,,,and now my bodies falling apart [3] funny,,,i dont remember being absent minded [5] funny
jimmyw123
in
Lung Conditions Community Forum
10 years ago
Constantly tired. Blood results- lymphocytes low. Two lr back surgeries..severe pain in foot and left leg. Have to repeat bloods Help needed
I am at the end of my patience. Pain is also in my shoulder/neck and lower back. had treatments of every kind, but has been some years now . Due to see Pain cons in two weeks. Love some direction as to how to approach him. On Nurontin..and antidepressant. Not much else as have a sensitivity to certain
I am at the end of my patience. Pain is also in my shoulder/neck and lower back. had treatments of every kind, but has been some years now . Due to see Pain cons in two weeks. Love some direction as to how to approach him. On Nurontin..and antidepressant. Not much else as have a sensitivity to certain
sweetpea-123
in
Pain Concern
10 years ago
gout in foot
Hello, I was diagnosed PD about 8 years ago, currently on carbidopa/levadopa and comtan. Tried all the other medications to no avail for various reasons. Currently developed gout in my foot. Anyone else experienced this? Don't know if it's related to PD or meds or???
Hello, I was diagnosed PD about 8 years ago, currently on carbidopa/levadopa and comtan. Tried all the other medications to no avail for various reasons. Currently developed gout in my foot. Anyone else experienced this? Don't know if it's related to PD or meds or???
jebbers
in
Cure Parkinson's
10 years ago
Pain in Legs
Does anyone get pain in their legs? i have been suffering for about 3 weeks now, especially at night. Its mostly from the knee down and my right leg is affected worse than the left. Its only down one side of my leg. I am having trouble sleeping because of it, painkillers are not helping.I got up this
Does anyone get pain in their legs? i have been suffering for about 3 weeks now, especially at night. Its mostly from the knee down and my right leg is affected worse than the left. Its only down one side of my leg. I am having trouble sleeping because of it, painkillers are not helping.I got up this
lindamorgan
in
Fibromyalgia Action UK
10 years ago
thyroid pain
so woke up with my neck more swollen -like beign cut with a knife,sore under jaw and swelling more on left side o f neck quite painful.difficulty swallowing and pain on doing so like it all day but worse in evening.i can feel my gland is definitely up .thinking I have all the symptoms -why doesn't
so woke up with my neck more swollen -like beign cut with a knife,sore under jaw and swelling more on left side o f neck quite painful.difficulty swallowing and pain on doing so like it all day but worse in evening.i can feel my gland is definitely up .thinking I have all the symptoms -why doesn't
anbuma
in
Thyroid UK
10 years ago
Pain relief for gout
My 45yr old husband has just been diagnosed with severe gout in his hands, wrists, elbows and really bad in his ankles. His gp gave him a very strong 3day course of colchicine tablets which did help, but it flared up again a few days after finishing the course. He is now on 1 colchicine aday and naproxin
My 45yr old husband has just been diagnosed with severe gout in his hands, wrists, elbows and really bad in his ankles. His gp gave him a very strong 3day course of colchicine tablets which did help, but it flared up again a few days after finishing the course. He is now on 1 colchicine aday and naproxin
mitzymoo
in
NRAS
10 years ago
Tingling and numb fingers
Hi, i was wondering if anybody has tips to help with tingling and numb fingers in the morning. The paon is quite bad and when i wake in the morning i cant use my hands as they have no feeling on the fingertips. This passes and then i have pain from my knuckles upwards. Im on arcoxia, colchine and pain
Hi, i was wondering if anybody has tips to help with tingling and numb fingers in the morning. The paon is quite bad and when i wake in the morning i cant use my hands as they have no feeling on the fingertips. This passes and then i have pain from my knuckles upwards. Im on arcoxia, colchine and pain
lollalettuce
in
LUPUS UK
10 years ago
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