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Glycine
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Supplement Reverses Hallmarks Of Old Age And Promotes Healthier Aging
The supplement "Glynac" (combination of
Glycine
and N-acetylcysteine) showed after 16 weeks of participants taking doses of 100 mg/kg/d each of
glycine
and NAC, was associated with a host of benefits for key hallmarks of aging and age-associated defects.
The supplement "Glynac" (combination of
Glycine
and N-acetylcysteine) showed after 16 weeks of participants taking doses of 100 mg/kg/d each of
glycine
and NAC, was associated with a host of benefits for key hallmarks of aging and age-associated defects.
Baron1
in
Cure Parkinson's
1 year ago
Selective amino acid restriction therapy (SAART)
Rapidly proliferating cancer cells from a variety of tissues, but not rapidly proliferating normal cells, are also vulnerable to
glycine
deprivation [47].
Rapidly proliferating cancer cells from a variety of tissues, but not rapidly proliferating normal cells, are also vulnerable to
glycine
deprivation [47].
pca2004
in
Fight Prostate Cancer
1 year ago
NMDA and AMPA are both synthesized chemicals that activate glutamate receptors, they incite glutamate excitotoxicity
The natural ligand for NMDARs is Glutamate (and to a lesser extent, Aspartate) but the receptors also require a co-agonist
Glycine
or D-serine for activation. There are two separate sub-units. NR1 (which binds
Glycine
) and NR2 (binds Glutamate).
The natural ligand for NMDARs is Glutamate (and to a lesser extent, Aspartate) but the receptors also require a co-agonist
Glycine
or D-serine for activation. There are two separate sub-units. NR1 (which binds
Glycine
) and NR2 (binds Glutamate).
SilentEchoes
in
Cure Parkinson's
1 year ago
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Glycine : said to reduce symptoms and reduce aggregation
https://www.michaeljfox.org/grant/modulation-
glycine
-treatment-parkinsons-disease
Glycine
and N-acetylcysteine (GlyNAC) supplementation in older adults improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfunction, genotoxicity
https://www.michaeljfox.org/grant/modulation-
glycine
-treatment-parkinsons-disease
Glycine
and N-acetylcysteine (GlyNAC) supplementation in older adults improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfunction, genotoxicity
Little_apple
in
Cure Parkinson's
2 years ago
Can Someone Explain this Paper?
Anyway, just for the heck of it, I googled
glycine
/B12 deficiency and found a couple scientific papers (most pertaining to chickens) and I found this one https://www.cell.com/cell/pdf/S0092-8674(17)31252-7.pdf It's way over my head but the title leads me to believe
glycine
has something to do with
Anyway, just for the heck of it, I googled
glycine
/B12 deficiency and found a couple scientific papers (most pertaining to chickens) and I found this one https://www.cell.com/cell/pdf/S0092-8674(17)31252-7.pdf It's way over my head but the title leads me to believe
glycine
has something to do with
MoKayD
in
Pernicious Anaemia Society
2 years ago
Anyone heard of or tried cGPmax?
Cyclic
glycine
-proline (cGP), a metabolite from the binding site of IGF-1, retains its affinity for IGFBP-3 and competes against IGF-1 for IGFBP-3 binding. Thus, cGP and IGFBP-3 collectively regulate the bioavailability of IGF-1.
Cyclic
glycine
-proline (cGP), a metabolite from the binding site of IGF-1, retains its affinity for IGFBP-3 and competes against IGF-1 for IGFBP-3 binding. Thus, cGP and IGFBP-3 collectively regulate the bioavailability of IGF-1.
LAJ12345
in
Cure Parkinson's
7 months ago
PID? not getting better - antibiotics
I have suspected endometriosis I'm on the waiting list for lap but recently for the past 6 months having intense burning and dull ache within vaginal canal, cervix as well as my lower pelvis and back pain ( of course when on period intense cramping sharp pain occurs alongside this or when heavy bleeding
I have suspected endometriosis I'm on the waiting list for lap but recently for the past 6 months having intense burning and dull ache within vaginal canal, cervix as well as my lower pelvis and back pain ( of course when on period intense cramping sharp pain occurs alongside this or when heavy bleeding
Littlebug77
in
Endometriosis UK
1 year ago
Problem with EBV
Hi all I have active EBV, but I can't take Lysine because it reduces my sleep-5,6 hours and I sleep very poorly by waking up several times during the night. My question is, is there anything else that can successfully replace Lysine. I've tried taking Valtrex, but I'm even worse off it, because it's
Hi all I have active EBV, but I can't take Lysine because it reduces my sleep-5,6 hours and I sleep very poorly by waking up several times during the night. My question is, is there anything else that can successfully replace Lysine. I've tried taking Valtrex, but I'm even worse off it, because it's
Stongwave
in
Thyroid UK
1 year ago
Thoughts on L lysine
Hi everyone, I suffer from cold sores and I wanted to know if anybody take L lysine along with the valtrex or acyclovir ? I have been having one outbreak after another , just trying to get this to calm down. Any suggestions greatly appreciated. Thank you !
Hi everyone, I suffer from cold sores and I wanted to know if anybody take L lysine along with the valtrex or acyclovir ? I have been having one outbreak after another , just trying to get this to calm down. Any suggestions greatly appreciated. Thank you !
Jances13
in
LUPUS UK
1 year ago
Medications, supplements and other therapies used in Parkinsons
Beta-secretase 1 inhibitors Glycogen synthase kinase-3 inhibitors Cholinesterase inhibitors Nicotinic acetylcholine receptor antagonists
Glycine
receptors modulators Neuronal growth inducers
Beta-secretase 1 inhibitors Glycogen synthase kinase-3 inhibitors Cholinesterase inhibitors Nicotinic acetylcholine receptor antagonists
Glycine
receptors modulators Neuronal growth inducers
healthyheart7
in
Cure Parkinson's
2 years ago
Iron levels still low - advice welcome
Hello, I've just done an Iron Panel re-test after 6-8 weeks of ferrous fumarate 1 x 69mg taken in the morning before food on alternate days, away from Levo and any other supplement apart from Vit D w K2 spray. I also take 125mcg Levo at night, B Complex & Copper w 1st meal (tested low in range in
Hello, I've just done an Iron Panel re-test after 6-8 weeks of ferrous fumarate 1 x 69mg taken in the morning before food on alternate days, away from Levo and any other supplement apart from Vit D w K2 spray. I also take 125mcg Levo at night, B Complex & Copper w 1st meal (tested low in range in
HotelHurricaine
in
Thyroid UK
1 year ago
Are you ready to kick neurotoxins to the curb?
https://www.ncbi.nlm.nih.gov/books/NBK499883/ From the label of the product I was poisoned with: ACTIVE INGREDIENT: *Glyphosate, N-(phosphonomethyl)
glycine
, in the form of its isopropylamine salt 41.0% "Contains 480 grams per litre or 4 pounds per U.S. gallon of the active ingredient glyphosate, in
https://www.ncbi.nlm.nih.gov/books/NBK499883/ From the label of the product I was poisoned with: ACTIVE INGREDIENT: *Glyphosate, N-(phosphonomethyl)
glycine
, in the form of its isopropylamine salt 41.0% "Contains 480 grams per litre or 4 pounds per U.S. gallon of the active ingredient glyphosate, in
SilentEchoes
in
Cure Parkinson's
9 months ago
Trialling Buprenorphine and Dipyramidole - experience
My iron was 52 in June and I got it up to 74 after three months’ supplementation with ferrous fumarate (I don’t tolerate bisglycinate because of the
glycine
in it). I tolerated it ok for a while but now I feel that the iron is exacerbating the RLS. Anyone else find this?
My iron was 52 in June and I got it up to 74 after three months’ supplementation with ferrous fumarate (I don’t tolerate bisglycinate because of the
glycine
in it). I tolerated it ok for a while but now I feel that the iron is exacerbating the RLS. Anyone else find this?
Typicallygaslit
in
Restless Legs Syndrome
2 years ago
Glycine + N-acetylcysteine
Biomedicines 2020, 8, 390; doi:10.3390/biomedicines8100390 Supplementing
Glycine
and N-acetylcysteine(GlyNAC) in Aging HIV Patients Improves Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Endothelial Dysfunction, Insulin Resistance, Genotoxicity, Strength, and Cognition: Results of an
Biomedicines 2020, 8, 390; doi:10.3390/biomedicines8100390 Supplementing
Glycine
and N-acetylcysteine(GlyNAC) in Aging HIV Patients Improves Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Endothelial Dysfunction, Insulin Resistance, Genotoxicity, Strength, and Cognition: Results of an
Purple-Bike
in
Advanced Prostate Cancer
2 years ago
Benfotiamine (Fat Soluble Form Of Vitamin B1) and AD
Benfotiamine has previously been discussed on this forum regarding PD and this recent study (October 2022) using Benfotiamine (BEN) in AD patients shows some significant benefit for people with AD : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585656/ Here are two relevant study quotes from this
Benfotiamine has previously been discussed on this forum regarding PD and this recent study (October 2022) using Benfotiamine (BEN) in AD patients shows some significant benefit for people with AD : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585656/ Here are two relevant study quotes from this
chartist
in
Cure Parkinson's
1 year ago
Increased aminoacids ... Could this be my gut issue
hi ive had amino acids profile tests done and there are increased levels of
glycine
;hydroproline; nithene; asparagine. Does anyone know what this means and could this be related to my gut pain? Thank you
hi ive had amino acids profile tests done and there are increased levels of
glycine
;hydroproline; nithene; asparagine. Does anyone know what this means and could this be related to my gut pain? Thank you
Waiting_for_godo
in
IBS Network
2 years ago
Plasma Metabolomics Reveals Systemic Metabolic Alterations of Subclinical and Clinical Hypothyroidism
This paper does what I have long been waiting for. Takes some blood, just the serum, and do a comprehensive analysis of pretty much everything they can detect in that serum. The subjects were divided into Control, Subclinical Hypothyroid and Hypothyroid groups. They found clear differences
This paper does what I have long been waiting for. Takes some blood, just the serum, and do a comprehensive analysis of pretty much everything they can detect in that serum. The subjects were divided into Control, Subclinical Hypothyroid and Hypothyroid groups. They found clear differences
helvella
Thyroid UK
in
Thyroid UK
2 years ago
Interferon Alpha 2-a (PEG) vs 2-b,(Bes) exactly what's the diff?
I posted this image recently, but here it's in a new context. For those who are curious exactly how 2-a and 2-b IFNs differ (I posted inside another thread before but here's a new post on it): https://www.prospecbio.com/interferon-alpha-2a_human "The difference between IFNA2A and IFNA2B is in the
I posted this image recently, but here it's in a new context. For those who are curious exactly how 2-a and 2-b IFNs differ (I posted inside another thread before but here's a new post on it): https://www.prospecbio.com/interferon-alpha-2a_human "The difference between IFNA2A and IFNA2B is in the
EPguy
in
MPN Voice
2 years ago
cold sores
Hi all, wondering if anyone knows if you can take Lysine tablet form when on MTX I’ve heard it prevents cold sores. Any help would be appreciated?
Hi all, wondering if anyone knows if you can take Lysine tablet form when on MTX I’ve heard it prevents cold sores. Any help would be appreciated?
Swanfull
in
NRAS
2 years ago
Lysine
Is Lysine good for us to take?
Is Lysine good for us to take?
Barbiebreath
in
MPN Voice
2 years ago
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