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TAPUR study
Following up on a genomics report (47 pages ! Plus 54 min consult) and came across this study (phase 2 basket trial) in the US. Essentially when exhausting, or before, standard of care options, allows patients to trial off label approved drugs using genomics to identify specific targetable variations
Following up on a genomics report (47 pages ! Plus 54 min consult) and came across this study (phase 2 basket trial) in the US. Essentially when exhausting, or before, standard of care options, allows patients to trial off label approved drugs using genomics to identify specific targetable variations
muzzatron
in
SHARE Metastatic Breast Cancer
8 months ago
everything feels weird
hi, I had a panic attack February last year and I’ve never been the same since. I’m now struggling with depression and anxiety , everyday feels a struggle to get through. Everything looks and feels totally different from what it was like before the panic attack and I am constantly thinking about it.
hi, I had a panic attack February last year and I’ve never been the same since. I’m now struggling with depression and anxiety , everyday feels a struggle to get through. Everything looks and feels totally different from what it was like before the panic attack and I am constantly thinking about it.
Lgns
in
Anxiety and Depression Support
3 months ago
for our 'newest' members....
Hi - and welcome! My name is Donna - I facilitate this support group for The PBC Foundation - Health Unlocked. If you are new to your diagnosis, first of all, take a breath. It’s ok. We all, myself included, have been exactly where you are right now…. scared, unsure, mad, sad, and so much more. Stop
Hi - and welcome! My name is Donna - I facilitate this support group for The PBC Foundation - Health Unlocked. If you are new to your diagnosis, first of all, take a breath. It’s ok. We all, myself included, have been exactly where you are right now…. scared, unsure, mad, sad, and so much more. Stop
DonnaBoll
Administrator
in
PBC Foundation
3 months ago
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Post ablation tubal sterilisation syndrome (PATTS)
Has anyone else had both of these surgeries and gone on to have excruciating pain? During my surgery they found endometriosis and I've since had an MRI and CT scan (as well as lots of useless ultrasounds that find nothing). I've been diagnosed with deep infiltrating endo on ovaries, peritoneum and bowel
Has anyone else had both of these surgeries and gone on to have excruciating pain? During my surgery they found endometriosis and I've since had an MRI and CT scan (as well as lots of useless ultrasounds that find nothing). I've been diagnosed with deep infiltrating endo on ovaries, peritoneum and bowel
MalachiteAli
in
Endometriosis UK
6 months ago
Feeling a bit nervous. What next?
Dear ladies, advice sought Am stage 4a and have had debulking surgery and chemo. Took Niraparib for a year but it stopped working and I had spread to my liver. I finished 6 rounds of chemo late Oct and had bloods and a CT scan. Chemo has shrunk the cancer in my liver so that was good news. My oncologist
Dear ladies, advice sought Am stage 4a and have had debulking surgery and chemo. Took Niraparib for a year but it stopped working and I had spread to my liver. I finished 6 rounds of chemo late Oct and had bloods and a CT scan. Chemo has shrunk the cancer in my liver so that was good news. My oncologist
Skyeplus
in
My Ovacome
8 months ago
Disability information
Biliary CirrhosisPrimary Biliary Cirrhosis – Condition and Symptoms The liver secretes bile, a bodily fluid that is essential for the body to digest fats. It also helps the body to rid itself of toxic substances, cholesterol, and worn-out red blood cells. The ducts that release bile can become damaged
Biliary CirrhosisPrimary Biliary Cirrhosis – Condition and Symptoms The liver secretes bile, a bodily fluid that is essential for the body to digest fats. It also helps the body to rid itself of toxic substances, cholesterol, and worn-out red blood cells. The ducts that release bile can become damaged
DonnaBoll
Administrator
in
PBC Foundation
3 months ago
Next steps after radiotherapy
Hi, In Oct 2023, My dad's MRI revealed that cancer had spread to few vertebral bones and has reached a rib bone. He got a PET scan and then underwent ~20 days of radiotherapy in Nov 2023. But his doctor has not asked him to do any follow-up tests after the radiotherapy ended. Is this the norm? Should
Hi, In Oct 2023, My dad's MRI revealed that cancer had spread to few vertebral bones and has reached a rib bone. He got a PET scan and then underwent ~20 days of radiotherapy in Nov 2023. But his doctor has not asked him to do any follow-up tests after the radiotherapy ended. Is this the norm? Should
QuestionsAbtMyDad
in
Prostate Cancer Network
8 months ago
NAC with ferritin deficiency or PA
Hi all. Just thought I’d pop in and ask my new friends if they know of any reason NAC shouldn’t be taken with iron tablets or B12, or whether NAC could actually have a negative effect on ferritin/B12 levels. Can’t find any info on this, so here I am 😊 I am awaiting latest blood results, so don’t
Hi all. Just thought I’d pop in and ask my new friends if they know of any reason NAC shouldn’t be taken with iron tablets or B12, or whether NAC could actually have a negative effect on ferritin/B12 levels. Can’t find any info on this, so here I am 😊 I am awaiting latest blood results, so don’t
MLJ2024
in
Pernicious Anaemia Society
6 months ago
Update on Cancer Diagnosis
Correction to recent post: I should have stated that I have been recently diagnosed with Lung Cancer. I could not see anywhere that I could edit my Post.
Correction to recent post: I should have stated that I have been recently diagnosed with Lung Cancer. I could not see anywhere that I could edit my Post.
cpt13
in
NRAS
8 months ago
Further to my post of 9 months ago
Hi Until December last I was taking 40 mg iron bisglycinate with orange juice every two days. Since this had little impact on my RLS I increased the iron dose to 40mg every day from December until now. As yet I have noticed little change to my RLS symptoms. A blood test this month showed my ferritin
Hi Until December last I was taking 40 mg iron bisglycinate with orange juice every two days. Since this had little impact on my RLS I increased the iron dose to 40mg every day from December until now. As yet I have noticed little change to my RLS symptoms. A blood test this month showed my ferritin
Rameau
in
Restless Legs Syndrome
5 months ago
Suspected IBS
I've had IBS symptoms for about 15 years. At first I thought it was intolerance to a few foods, and cutting those out seemed to help. But the symptoms seem to get worse and more frequent as I age. I am now 42 and get scared to go out to eat or be in the office all day (thankfully I WFH 4 days a week)
I've had IBS symptoms for about 15 years. At first I thought it was intolerance to a few foods, and cutting those out seemed to help. But the symptoms seem to get worse and more frequent as I age. I am now 42 and get scared to go out to eat or be in the office all day (thankfully I WFH 4 days a week)
Gaia_1
in
IBS Network
6 months ago
SE's on Cabazitaxel/Carboplatin Combo
Fellow chemo warriors: I'm hoping your experiences can shed some light on my latest treatment variation. Long story short: I had 3 docetaxel infusions with zero side effects. Unfortunately, the response was only partial, so last week I started on Cab/Carboplatin combo. This has been a very different
Fellow chemo warriors: I'm hoping your experiences can shed some light on my latest treatment variation. Long story short: I had 3 docetaxel infusions with zero side effects. Unfortunately, the response was only partial, so last week I started on Cab/Carboplatin combo. This has been a very different
CrocodileShoes
in
Advanced Prostate Cancer
8 months ago
PMR again ?
I stopped pred on 8th October after 4 years and was OK until now. I have developed stiffness and aching in hips down to knees and am wondering whether the PMR has come again due to stress. I was diagnosed with breast cancer on 11th October and am currently on Letrozole to (hopefully !) shrink the tumour
I stopped pred on 8th October after 4 years and was OK until now. I have developed stiffness and aching in hips down to knees and am wondering whether the PMR has come again due to stress. I was diagnosed with breast cancer on 11th October and am currently on Letrozole to (hopefully !) shrink the tumour
Retallack
in
PMRGCAuk
8 months ago
Restart
I completed couch to 5k a few years ago & loved the experience - I was then addicted to running, to the freedom, how it helped clear my mind, distressed me, made me fitter, I could go on . However in November 2022 I got the worst news ever- I had cancer - by December 25th I was laid in hospital after
I completed couch to 5k a few years ago & loved the experience - I was then addicted to running, to the freedom, how it helped clear my mind, distressed me, made me fitter, I could go on . However in November 2022 I got the worst news ever- I had cancer - by December 25th I was laid in hospital after
MissTwiggy
Graduate
in
Couch to 5K
8 months ago
Finding strength to keep going
hi guys. This is my first post on here and am brand new to the site. I have had severe anxiety and panic disorder my entire life and it has essentially controlled my life. Every single day, I battle against it all to just even live, let alone enjoy myself. I have come a long way since I was little
hi guys. This is my first post on here and am brand new to the site. I have had severe anxiety and panic disorder my entire life and it has essentially controlled my life. Every single day, I battle against it all to just even live, let alone enjoy myself. I have come a long way since I was little
NurturingNature
in
Anxiety and Depression Support
3 months ago
Generic B12-symptoms news article
Occasionally I see what I call a generic news article on issues pertaining to B12 deficiency. Typically the articles are not very good, misrepresenting some things, wrong about other things, and so forth. So I was surprised today when I saw one that is not so bad. Sure, it could be better, could be more
Occasionally I see what I call a generic news article on issues pertaining to B12 deficiency. Typically the articles are not very good, misrepresenting some things, wrong about other things, and so forth. So I was surprised today when I saw one that is not so bad. Sure, it could be better, could be more
WiscGuy
in
Pernicious Anaemia Society
6 months ago
Ibs sufferer any advice for nausea
hi 44 yr old in last 8 mths diagnosed with ibs m had a colonoscopy , bloods , stools samples taken and also had upper gi and ct scan with contrast all normal except calprocetin levels where high hence referral to gastologist My symptoms vary on flare up sometimes I be sat then all sudden I get funny
hi 44 yr old in last 8 mths diagnosed with ibs m had a colonoscopy , bloods , stools samples taken and also had upper gi and ct scan with contrast all normal except calprocetin levels where high hence referral to gastologist My symptoms vary on flare up sometimes I be sat then all sudden I get funny
Foody79
in
IBS Network
6 months ago
Metaxalone.
I was diagnosed with PMR September 2023 but I'm unable to have steroids. Due to a heart condition I'm also unable to have Immuno suppresants. My Rheumy has now prescribed Metaxalone for pain relief. Reading the side effects I'm not sure I'm happy to take them as they can affect your kidneys and liver
I was diagnosed with PMR September 2023 but I'm unable to have steroids. Due to a heart condition I'm also unable to have Immuno suppresants. My Rheumy has now prescribed Metaxalone for pain relief. Reading the side effects I'm not sure I'm happy to take them as they can affect your kidneys and liver
Joann63
in
PMRGCAuk
6 months ago
Is it safe to take mesalazine/octasa long term?
Hi everyone, I'm Claire and was diagnosed with mild/moderative ulcerative colitis last year. Apart from an initial flare up (followed by diagnostic procedures leading to the diagnosis), my only symptoms have been an uncomfortable/slightly painful feeling in my stomach/upper intestine. My gastroenterologist
Hi everyone, I'm Claire and was diagnosed with mild/moderative ulcerative colitis last year. Apart from an initial flare up (followed by diagnostic procedures leading to the diagnosis), my only symptoms have been an uncomfortable/slightly painful feeling in my stomach/upper intestine. My gastroenterologist
Claire_lc
in
Crohn's and Colitis Support
6 months ago
Prostatic Artery Embolization
I’m 67 year old and have been suffering with BPH for years. Don’t want to do TURP or lasers. I’m interested in doing PAE. Has anyone had this procedure done. Does it work. I had a cystoscope and the urologist found a medial lobe at the neck of the bladder. Would PAE work if the blockage is located there
I’m 67 year old and have been suffering with BPH for years. Don’t want to do TURP or lasers. I’m interested in doing PAE. Has anyone had this procedure done. Does it work. I had a cystoscope and the urologist found a medial lobe at the neck of the bladder. Would PAE work if the blockage is located there
Roenken
in
Men's Health Forum
8 months ago
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