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Nicotinamide riboside supplementation is not associated with altered methylation homeostasis in Parkinson`s disease.
https://www.cell.com/iscience/fulltext/S2589-0042(23)00355-3 Highlights • NR 1000mg/day for 30 days does not alter the global DNA methylation profile in blood • NR does not impact DNA methylation in individuals carrying common MTHFR mutations • Pathway and methylation variance analyses indicate
https://www.cell.com/iscience/fulltext/S2589-0042(23)00355-3 Highlights • NR 1000mg/day for 30 days does not alter the global DNA methylation profile in blood • NR does not impact DNA methylation in individuals carrying common MTHFR mutations • Pathway and methylation variance analyses indicate
Hidden
in
Cure Parkinson's
1 year ago
Lost a dear friend yesterday from complications of pneumonia
He had methesilioma and been hospitalised twice since Christmas with infection and pneumonia. He will be missed ❤️
He had methesilioma and been hospitalised twice since Christmas with infection and pneumonia. He will be missed ❤️
B0xermad
in
Lung Conditions Community Forum
1 year ago
Rage at GP
Sorry all I need to rant. Just back from GP appointment and I am outraged. Explained to him about my extreme levels of pain and his response was that people with "fibro" lead normal lives and that the diagnosis is given when the consultant doesn't know what's wrong with you!!! Said the pain clinic
Sorry all I need to rant. Just back from GP appointment and I am outraged. Explained to him about my extreme levels of pain and his response was that people with "fibro" lead normal lives and that the diagnosis is given when the consultant doesn't know what's wrong with you!!! Said the pain clinic
Macdoual
in
Fibromyalgia Action UK
11 months ago
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Thoughts on L lysine
Hi everyone, I suffer from cold sores and I wanted to know if anybody take L lysine along with the valtrex or acyclovir ? I have been having one outbreak after another , just trying to get this to calm down. Any suggestions greatly appreciated. Thank you !
Hi everyone, I suffer from cold sores and I wanted to know if anybody take L lysine along with the valtrex or acyclovir ? I have been having one outbreak after another , just trying to get this to calm down. Any suggestions greatly appreciated. Thank you !
Jances13
in
LUPUS UK
11 months ago
"Long Covid" FYI
Listen from 20mins if you want to skip the beginning, its very technical. And apparently the video link is not working so go to Youtube and type in Professor Clancy, long covid and immunity A great interview with prof. Robert Clancy. He is a retired Australian clinical immunologist in the field
Listen from 20mins if you want to skip the beginning, its very technical. And apparently the video link is not working so go to Youtube and type in Professor Clancy, long covid and immunity A great interview with prof. Robert Clancy. He is a retired Australian clinical immunologist in the field
TonyB1972
in
AF Association
1 year ago
Looking for a Surgeon with Specific Skills
This is a long shot. I’m an Aussie. I had HD brachytherapy for prostate cancer in 2010. In 2016, I was diagnosed with Carcinoma in Situ in the bladder. I’ve had multiple rounds of BCG, and I’m now heading towards a radical cystectomy. My urologist is nervous about the risk of damage to the rectum
This is a long shot. I’m an Aussie. I had HD brachytherapy for prostate cancer in 2010. In 2016, I was diagnosed with Carcinoma in Situ in the bladder. I’ve had multiple rounds of BCG, and I’m now heading towards a radical cystectomy. My urologist is nervous about the risk of damage to the rectum
Anthonyve
in
Advanced Prostate Cancer
11 months ago
recent Covid infection and sle activity
hello everyone! So I’ve had sle since I was 13- it was rough then but then it was mild all along. I tested positive for Covid about 3 days ago - annoying sore throat, congestion and body aches, now feeling better but I’m starting to feel like my joints, specially my elbow and knees are aching. I’m
hello everyone! So I’ve had sle since I was 13- it was rough then but then it was mild all along. I tested positive for Covid about 3 days ago - annoying sore throat, congestion and body aches, now feeling better but I’m starting to feel like my joints, specially my elbow and knees are aching. I’m
Jamzie
in
LUPUS UK
1 year ago
anyone been tested for perimenopause?
hey - just got my period again 11 days after I started the last one. It’s not the first time in the last 2 years that I’ve had a really short period like this but it’s definitely the shortest - and I thought there was nothing y around this data that could have set it off -8 don’t have covid, haven’t
hey - just got my period again 11 days after I started the last one. It’s not the first time in the last 2 years that I’ve had a really short period like this but it’s definitely the shortest - and I thought there was nothing y around this data that could have set it off -8 don’t have covid, haven’t
ForABabyPanda
in
Endometriosis UK
1 year ago
anyone been tested for perimenopause?
hey - just got my period again 11 days after I started the last one. It’s not the first time in the last 2 years that I’ve had a really short period like this but it’s definitely the shortest - and I thought there was nothing y around this data that could have set it off -8 don’t have covid, haven’t
hey - just got my period again 11 days after I started the last one. It’s not the first time in the last 2 years that I’ve had a really short period like this but it’s definitely the shortest - and I thought there was nothing y around this data that could have set it off -8 don’t have covid, haven’t
ForABabyPanda
in
Fertility Network UK
1 year ago
Covid
Also know of 7 people who came away from a wedding with covid.
Also know of 7 people who came away from a wedding with covid.
Wantplaytennis
in
NRAS
1 year ago
second vasectomy reversal- waiting results. Has anyone got a similar story?
My husband and I have been together 7 years. He had vasectomy from previous relationship, he is 11 years older than me and has a 13 y/o son. Fast forward us being together and me being only 26/27 he had a vasectomy reversal about 4 years after the vasectomy. It was successful and we have a beautiful
My husband and I have been together 7 years. He had vasectomy from previous relationship, he is 11 years older than me and has a 13 y/o son. Fast forward us being together and me being only 26/27 he had a vasectomy reversal about 4 years after the vasectomy. It was successful and we have a beautiful
Shaketheglitter
in
Fertility Network UK
11 months ago
Did Covid vaccination cause Fb/ME/CFS?
Hi everyone. Just wondering if there is anyone else out there who's Fb/ME/CFS started after their Covid vaccination!?
Hi everyone. Just wondering if there is anyone else out there who's Fb/ME/CFS started after their Covid vaccination!?
Bethenny
in
Fibromyalgia Action UK
1 year ago
frustrated with restriction of naproxen
After an unsuccessful spinal fusion surgery in 2001(and 2 more since) I’ve been taking naproxen for about 15 years and get that together with a long list of other pain meds every 3 months,I’ve now been told I can only have 2 month supply of naproxen at a time which is messing up my repeat meds routine
After an unsuccessful spinal fusion surgery in 2001(and 2 more since) I’ve been taking naproxen for about 15 years and get that together with a long list of other pain meds every 3 months,I’ve now been told I can only have 2 month supply of naproxen at a time which is messing up my repeat meds routine
Paiger1
in
NRAS
1 year ago
"A revolution in cancer treatment?"
I don't see a specific reference to prostate cancer in this article in today's NYTimes. But it's about multiple cancers, and the idea, spoken of here before, is that patients with cancers formerly called terminal are living longer and longer as multiple drug treatments may come close to turning these
I don't see a specific reference to prostate cancer in this article in today's NYTimes. But it's about multiple cancers, and the idea, spoken of here before, is that patients with cancers formerly called terminal are living longer and longer as multiple drug treatments may come close to turning these
billfenley2
in
Advanced Prostate Cancer
11 months ago
Covid antivirals - why?
NHS have told me I have a condition that entitles me to antivirals for Covid. But haven't told me what is or which are the qualifying condition(s). GP doesn't know either. I think this is off! Makes me worry, and I'm not easily fazed. Is it an existing condition, if so which, or is it a new condition
NHS have told me I have a condition that entitles me to antivirals for Covid. But haven't told me what is or which are the qualifying condition(s). GP doesn't know either. I think this is off! Makes me worry, and I'm not easily fazed. Is it an existing condition, if so which, or is it a new condition
Coppernob
in
Aspergillosis and Rare Fungal Infection Support
1 year ago
Cellulitis and ET
I’ve seen a nurse at my GP practice today (no doctors in!) I’ve got red swollen lower legs, that feel warm. She said it’s cellulitis and I’ve got antibiotics to take. Surprisingly she said she’d heard of ET, but just knew it was something to do with blood. Anyway apparently I’ve caught it early. She
I’ve seen a nurse at my GP practice today (no doctors in!) I’ve got red swollen lower legs, that feel warm. She said it’s cellulitis and I’ve got antibiotics to take. Surprisingly she said she’d heard of ET, but just knew it was something to do with blood. Anyway apparently I’ve caught it early. She
lizzziep
in
MPN Voice
1 year ago
Persistent cough
Hi All, I don't know of anyone can assist me in this complex enquiry, I will give it a try and keep it brief. I have CLL and am seeing my Haematologist on Monday, regarding persistent cough, night and day sweats, and a viral infection I have had on and off for 6 months. I have had a Chest X Ray and
Hi All, I don't know of anyone can assist me in this complex enquiry, I will give it a try and keep it brief. I have CLL and am seeing my Haematologist on Monday, regarding persistent cough, night and day sweats, and a viral infection I have had on and off for 6 months. I have had a Chest X Ray and
Vindicatrix
in
Lung Conditions Community Forum
1 year ago
New Hepatitis C page - British Liver Trust website
The
NEW
hepatitis C page is now live on the website. We're delighted to say that this came about with the involvement of one of our forum members, for which we're very grateful. Here's the link: https://britishlivertrust.org.uk/information-and-support/living-with-a-liver-condition/liver-conditions
The
NEW
hepatitis C page is now live on the website. We're delighted to say that this came about with the involvement of one of our forum members, for which we're very grateful. Here's the link: https://britishlivertrust.org.uk/information-and-support/living-with-a-liver-condition/liver-conditions
BritishLiverTrust1
Partner
in
British Liver Trust
1 year ago
covid
hi all. I have severe asthma. Which I have had for many years. I had covid in June last year. Followed by chest infection, then I was hospitalised with RSV. I spent all of Xmas in hospital after I also got flu a few weeks after that , I have never been right since I had covid. I went to the post
hi all. I have severe asthma. Which I have had for many years. I had covid in June last year. Followed by chest infection, then I was hospitalised with RSV. I spent all of Xmas in hospital after I also got flu a few weeks after that , I have never been right since I had covid. I went to the post
Denae011
in
Lung Conditions Community Forum
1 year ago
W8r3 developed a dry cough?
been enjoying my runs and really proud to reach 28 minutes running ! never been able to run ( well jog) before due to knee problems but yep am there! this week though I seem to have a very dry throat and tickly cough? I’ve been running on the treadmill- gym is air conditioned- and the dry tickly throat
been enjoying my runs and really proud to reach 28 minutes running ! never been able to run ( well jog) before due to knee problems but yep am there! this week though I seem to have a very dry throat and tickly cough? I’ve been running on the treadmill- gym is air conditioned- and the dry tickly throat
JoggingAnnie4
in
Couch to 5K
1 year ago
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