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5th jab yesterday
5th Covid Jane yesterday. Very well administered, didn't feel d thing. Arm became sore last night,woke at 3am with shivers,electric blanket went on at full blast! And 2 paracetamol. 8am a tad disorientated, and felt nauseous. Another 2 paracetamol. Now in bed wishing I'd never had the jab, 5th
5th Covid Jane yesterday. Very well administered, didn't feel d thing. Arm became sore last night,woke at 3am with shivers,electric blanket went on at full blast! And 2 paracetamol. 8am a tad disorientated, and felt nauseous. Another 2 paracetamol. Now in bed wishing I'd never had the jab, 5th
MamaBeagle
in
PMRGCAuk
2 years ago
BFP 9dp5dt but more faint line next evening
hi ladies, I know I shouldn’t have but I decided to test yesterday morning, as had a good feeling I would get a positive, following what I believe was implantation bleeding last Wednesday. My OTD is Wednesday (29th). The line indicating a positive result came up pretty much straight away and was very
hi ladies, I know I shouldn’t have but I decided to test yesterday morning, as had a good feeling I would get a positive, following what I believe was implantation bleeding last Wednesday. My OTD is Wednesday (29th). The line indicating a positive result came up pretty much straight away and was very
Louanne33
in
Fertility Network UK
1 year ago
Sensitive: is ectopic 'vanishingly rare' with IVF?
Thank you to everyone who has been so kind with their advice and checking in. I spent a long time at the EPU today with a pretty confusing outcome - the nurse who scanned me said there was a gestational sac but nothing else, and that my right ovary that she could see looked fine, no cysts etc. Definitely
Thank you to everyone who has been so kind with their advice and checking in. I spent a long time at the EPU today with a pretty confusing outcome - the nurse who scanned me said there was a gestational sac but nothing else, and that my right ovary that she could see looked fine, no cysts etc. Definitely
MrsOrangejuice
in
Fertility Network UK
1 year ago
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Chronic lymphocytic leukemia treatment algorithm 2022
This 29 November 2022 review article published in the [i]Blood Cancer Journal[/i] presents an up-to-date treatment algorithm for CLL. https://www.nature.com/articles/s41408-022-00756-9 [i]"The treatment landscape for patients with chronic lymphocytic leukemia (CLL) has changed considerably with the
This 29 November 2022 review article published in the [i]Blood Cancer Journal[/i] presents an up-to-date treatment algorithm for CLL. https://www.nature.com/articles/s41408-022-00756-9 [i]"The treatment landscape for patients with chronic lymphocytic leukemia (CLL) has changed considerably with the
CLLerinOz
Administrator
in
CLL Support
2 years ago
Stopped using Evusheld
I received this message from UCSF. I believe, soon they will stop using it everywhere else too. In recent weeks, California has seen a rapid increase and dominance in circulation of COVID-19 Omicron subvariants which are resistant to our current monoclonal antibody treatment (bebtelovimab) and prophylaxis
I received this message from UCSF. I believe, soon they will stop using it everywhere else too. In recent weeks, California has seen a rapid increase and dominance in circulation of COVID-19 Omicron subvariants which are resistant to our current monoclonal antibody treatment (bebtelovimab) and prophylaxis
shazie
in
CLL Support
2 years ago
My TMS journey, another update...
Hello all, i'm down to two sessions a week and I had a relapse this last weekend and am bumbed about it to say the least. I'm not sure if it is due to the TMS but doubt it and I have an appointment Monday with the psychologist/clinic director on Monday to discuss it. I am also on TRT (testosterone
Hello all, i'm down to two sessions a week and I had a relapse this last weekend and am bumbed about it to say the least. I'm not sure if it is due to the TMS but doubt it and I have an appointment Monday with the psychologist/clinic director on Monday to discuss it. I am also on TRT (testosterone
designguy
in
Anxiety and Depression Support
1 year ago
Fed Up with everything.
I have been on haemodialysis since May. Having completed all the tests etc at the beginning of November, I was just waiting to go live in the transplant list. My previous consultant, who is now on maternity leave, said my results were good and she even said, I would probably receive a new kidney before
I have been on haemodialysis since May. Having completed all the tests etc at the beginning of November, I was just waiting to go live in the transplant list. My previous consultant, who is now on maternity leave, said my results were good and she even said, I would probably receive a new kidney before
Ziggydoodah
in
Kidney Dialysis
2 years ago
Promising research is currently underway to use humanized bispecific single-domain antibodies
I was wondering if anyone has seen this new trial for applicable candidates https://cllsociety.org/2022/11/ash-2021-bispecific-v%CE%B39v%CE%B42-t-and-type-1-nkt-cell-engager-lava-051-as-first-in-class-clinical-candidate-to-target-cd1d-expressing-cll-mm-and-aml/ ASH 2021: Bispecific Vγ9Vδ2-T and
I was wondering if anyone has seen this new trial for applicable candidates https://cllsociety.org/2022/11/ash-2021-bispecific-v%CE%B39v%CE%B42-t-and-type-1-nkt-cell-engager-lava-051-as-first-in-class-clinical-candidate-to-target-cd1d-expressing-cll-mm-and-aml/ ASH 2021: Bispecific Vγ9Vδ2-T and
spi3
in
CLL Support
2 years ago
*update* Sensitive: HCG plateaued and clinic not offering any help
As everyone has been so supportive and helpful a quick but rather sad update: went for a private scan today and they couldn't see anything like a viable pregnancy - just a mass of what they called septations (no idea), possibly a haematoma and fluid. They couldn't see the tubes and only one ovary (with
As everyone has been so supportive and helpful a quick but rather sad update: went for a private scan today and they couldn't see anything like a viable pregnancy - just a mass of what they called septations (no idea), possibly a haematoma and fluid. They couldn't see the tubes and only one ovary (with
MrsOrangejuice
in
Fertility Network UK
1 year ago
5+4 weeks with tested embryo and good HCG results but terrified for viability scan
Hi all, I'm newly pregnant (currently 5.4 weeks). I've had two good HCG blood test results, the first was >700 at 12dp6dt and the second was >1800 at 14dpt. My clinic says these are good numbers and don't recommend I test again, but I'm already struggling with the wait for the viability scan. I'm terrified
Hi all, I'm newly pregnant (currently 5.4 weeks). I've had two good HCG blood test results, the first was >700 at 12dp6dt and the second was >1800 at 14dpt. My clinic says these are good numbers and don't recommend I test again, but I'm already struggling with the wait for the viability scan. I'm terrified
Mudra85
in
Fertility Network UK - Pregnancy Support
1 year ago
STATIC now beginning to open at sites in the UK
The long awaited successor to FLAIR for patients randomised to one of the Ibrutinib arms is finally ready to open at sites in the UK. When each site is ready will be up to local researchers and resource availability but the trial will be conducted in 100 NHS Centres in the UK (England, Wales, Scotland
The long awaited successor to FLAIR for patients randomised to one of the Ibrutinib arms is finally ready to open at sites in the UK. When each site is ready will be up to local researchers and resource availability but the trial will be conducted in 100 NHS Centres in the UK (England, Wales, Scotland
Jm954
Administrator
in
CLL Support
2 years ago
Could Members With Experience of PBC Without A Gallbladder Feels Like , Is Treatment and Diagnosis done the same way? Thanks
I was recently also diagnosed with Vitamin B 12 Anaemia/sero negative PA , I have malabsorption problems that cause regular Vitamin D deficiency and have
Chronic
Migraine
and Fatigue syndromes. Basically , I have many health issues that either link to my EDS and Autoimmunity.
I was recently also diagnosed with Vitamin B 12 Anaemia/sero negative PA , I have malabsorption problems that cause regular Vitamin D deficiency and have
Chronic
Migraine
and Fatigue syndromes. Basically , I have many health issues that either link to my EDS and Autoimmunity.
Blearyeyed
in
PBCers Organization
2 years ago
6 weeks pregnancy with abnormal vaginal bleeding
Hello everyone, So I rushed to the ER yesterday morning wednsday march 15th 2023 as my bleeding got worse i had sudden bleeding as they call it , and I had some more bleeding today, My hcg level was at a 4,000 no definite pregnancy was detected💔😔they also said my uterine lining had thickened ?
Hello everyone, So I rushed to the ER yesterday morning wednsday march 15th 2023 as my bleeding got worse i had sudden bleeding as they call it , and I had some more bleeding today, My hcg level was at a 4,000 no definite pregnancy was detected💔😔they also said my uterine lining had thickened ?
Bvegaa17
in
Pregnancy and Parenting Support
1 year ago
Concise summary of the treatment history of CLL from the 1950s to the present, by Dr Bruce Cheson, contributor to the iwCLL and much more
I knew Chlorambucil use for CLL dated back to the 1950's but I hadn't appreciated that was also the case for cyclophosphamide, (the 'C' in FCR). It took until the early 90's before Fludarabine, the 'F' in FCR joined, then Rituximab (the 'R') just over 20 years ago, started the long reign of FCR as the
I knew Chlorambucil use for CLL dated back to the 1950's but I hadn't appreciated that was also the case for cyclophosphamide, (the 'C' in FCR). It took until the early 90's before Fludarabine, the 'F' in FCR joined, then Rituximab (the 'R') just over 20 years ago, started the long reign of FCR as the
AussieNeil
Partner
in
CLL Support
2 years ago
Late ovulation on Letrozole/Femara?
Hi all, I did a medicated cycle last months (5 days of letrozole + HCG trigger + progesterone pessaries for luteal phase). By day 14 I was experiencing usual ovulation signs and the follicle was large enough, so I was triggered day 14. This cycle i'm away so I am unmonitored. It's day 14 and i've
Hi all, I did a medicated cycle last months (5 days of letrozole + HCG trigger + progesterone pessaries for luteal phase). By day 14 I was experiencing usual ovulation signs and the follicle was large enough, so I was triggered day 14. This cycle i'm away so I am unmonitored. It's day 14 and i've
CarlottaD27
in
Fertility Network UK
1 year ago
Negative home pregnancy test/ HCG test tomorrow is it all over?
Hi, Ladies. I hope you are all doing ok. 💕💕💕🌸🌸🌸🌸🌸💕💕💕💕💕💕💕 I have just had my two embryos (day five blastocysts) fet on March 3rd 2023. So here it goes. I had implantation bleeding on day 5, took a pregnancy test, and it showed faint line (positive) doctor told me to check progesterone
Hi, Ladies. I hope you are all doing ok. 💕💕💕🌸🌸🌸🌸🌸💕💕💕💕💕💕💕 I have just had my two embryos (day five blastocysts) fet on March 3rd 2023. So here it goes. I had implantation bleeding on day 5, took a pregnancy test, and it showed faint line (positive) doctor told me to check progesterone
Storm4
in
Fertility Network UK
1 year ago
Treatment-naive or relapsed CLL patients will soon have zanubrutinib/Brukinsa as a treatment option in the EU
[i]The EC approval is based on positive results from two Phase 3 clinical trials: SEQUOIA (NCT03336333), in patients with previously untreated CLL, and ALPINE (NCT03734016), in patients with R/R CLL. In these two trials, BRUKINSA demonstrated superior efficacy versus either bendamustine plus rituximab
[i]The EC approval is based on positive results from two Phase 3 clinical trials: SEQUOIA (NCT03336333), in patients with previously untreated CLL, and ALPINE (NCT03734016), in patients with R/R CLL. In these two trials, BRUKINSA demonstrated superior efficacy versus either bendamustine plus rituximab
AussieNeil
Partner
in
CLL Support
2 years ago
Looks like it’s all over 😢
Second FET, positive test on OTD but not looking good, I should be 6 weeks + 2, after 2 days of spotting and mild cramps went to EPU yesterday to say they can’t seeing anything. Blood tests show HCG levels are very low and no where near what they should be. Another blood is scheduled for tomorrow but
Second FET, positive test on OTD but not looking good, I should be 6 weeks + 2, after 2 days of spotting and mild cramps went to EPU yesterday to say they can’t seeing anything. Blood tests show HCG levels are very low and no where near what they should be. Another blood is scheduled for tomorrow but
Bonita928
in
Fertility Network UK
1 year ago
Peritoneal dialysis and Neck pain at night during exchanges ……any help? Asking for my mother
Reaching out to this expert community to see if anyone has any experience and advice so I can help my mother. She has been on peritoneal dialysis for about 3-4years. Her exchanges happen at night on machine (not manually). Most recently she has been dealing with pretty significant neck pain. That happens
Reaching out to this expert community to see if anyone has any experience and advice so I can help my mother. She has been on peritoneal dialysis for about 3-4years. Her exchanges happen at night on machine (not manually). Most recently she has been dealing with pretty significant neck pain. That happens
Fight2016
in
Kidney Dialysis
2 years ago
pain and docs.
my fibro has changed because of the weather ,I am not sleeping properly ,I have pain all over ,migraines ,been to doctors to see if they can give me anything for pain and migraine ,they said they cannot give anything strong for my pain they suggested ibuprofen , it does not work it gives me more problems
my fibro has changed because of the weather ,I am not sleeping properly ,I have pain all over ,migraines ,been to doctors to see if they can give me anything for pain and migraine ,they said they cannot give anything strong for my pain they suggested ibuprofen , it does not work it gives me more problems
Hidden
in
Fibromyalgia Action UK
2 years ago
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