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It’s official Study shows T cells are activated against Covid after vaccination
Just heard on the Irish Radio from Professor Luke O’Neill, a super immunologist in Trinity College Dublin, results of a study on Leukemia patients show T Cells show response to the vaccine. Sorry I can’t remember the name of the study he mentioned . Great news he thought. It’s nature.com and Eureka
Just heard on the Irish Radio from Professor Luke O’Neill, a super immunologist in Trinity College Dublin, results of a study on Leukemia patients show T Cells show response to the vaccine. Sorry I can’t remember the name of the study he mentioned . Great news he thought. It’s nature.com and Eureka
Hidden
in
CLL Support
3 years ago
Hcg
When does hcg stop doubling? My bloods have been 10dp5dt 223 12dp5dt 448 17dp5dt 3630 19dp5dt 5683 So they have doubled perfectly till my 19dp5dt I was expecting it over 7000…. Has anyone’s numbers stopped doubling this early?
When does hcg stop doubling? My bloods have been 10dp5dt 223 12dp5dt 448 17dp5dt 3630 19dp5dt 5683 So they have doubled perfectly till my 19dp5dt I was expecting it over 7000…. Has anyone’s numbers stopped doubling this early?
Hopedream
in
Fertility Network UK
3 years ago
First results of a head-to-head trial of acalabrutinib versus ibrutinib in previously treated chronic lymphocytic leukemia.
Background: Increased selectivity of the Bruton tyrosine kinase inhibitor (BTKi) acalabrutinib (Aca) vs ibrutinib (Ib) may improve tolerability. We conducted an open-label, randomized, noninferiority, phase 3 trial to compare Aca vs Ib in patients (pts) with chronic lymphocytic leukemia (CLL). Methods
Background: Increased selectivity of the Bruton tyrosine kinase inhibitor (BTKi) acalabrutinib (Aca) vs ibrutinib (Ib) may improve tolerability. We conducted an open-label, randomized, noninferiority, phase 3 trial to compare Aca vs Ib in patients (pts) with chronic lymphocytic leukemia (CLL). Methods
Jm954
Administrator
in
CLL Support
3 years ago
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CLL: from molecular pathogenesis to novel therapeutic strategies
September 2020 An interesting paper "CLL is a well-defined lymphoid neoplasm with very heterogeneous biological and clinical behavior. The last decade has been remarkably fruitful in novel findings elucidating multiple aspects of the pathogenesis of the disease. These include mechanisms of genetic susceptibility
September 2020 An interesting paper "CLL is a well-defined lymphoid neoplasm with very heterogeneous biological and clinical behavior. The last decade has been remarkably fruitful in novel findings elucidating multiple aspects of the pathogenesis of the disease. These include mechanisms of genetic susceptibility
Jm954
Administrator
in
CLL Support
3 years ago
The Lambda variant is now in 29 countries, but what evidence do we have that it’s more dangerous?
...........................................A variant of interest is one that has mutations that are predicted or known to affect things such as transmissibility (how easily the virus spreads), severity of disease, ability to evade immunity from past infections or vaccines, or confound diagnostic tests
...........................................A variant of interest is one that has mutations that are predicted or known to affect things such as transmissibility (how easily the virus spreads), severity of disease, ability to evade immunity from past infections or vaccines, or confound diagnostic tests
2greys
in
Lung Conditions Community Forum
3 years ago
News - Acalabrutinib approved for Restricted use in Scotland
Following an abbreviated and full submissions, the Scottish Medicines Consortium has approved Acalabrutinib for CLL with the following restrictions:
[i]*for the treatment of adult patients with previously untreated CLL without a del(17p) or TP53 mutation and who are [/i]
[i][u]ineligible[/
Following an abbreviated and full submissions, the Scottish Medicines Consortium has approved Acalabrutinib for CLL with the following restrictions:
[i]*for the treatment of adult patients with previously untreated CLL without a del(17p) or TP53 mutation and who are [/i]
[i][u]ineligible[/
Jm954
Administrator
in
CLL Support
3 years ago
5.5 weeks pregnant and bleeding. Stopped to brown blood over weekend and now at 6.3 bleeding again help
This is a never ending struggle. (So sorry for the long post. Just wanted to give you lots of info to help) History: Just turned 40 Stage 4 endometriosis latest lap Nov 2019 Conceived naturally and miscarried at 7.2 weeks Lots of chemical losses Lots of negatives Started IVF last October 1st cycle
This is a never ending struggle. (So sorry for the long post. Just wanted to give you lots of info to help) History: Just turned 40 Stage 4 endometriosis latest lap Nov 2019 Conceived naturally and miscarried at 7.2 weeks Lots of chemical losses Lots of negatives Started IVF last October 1st cycle
MagicSpark
in
Fertility Network UK
3 years ago
Hcg
The hospital has just called, my hcg is lower than they would like, it is only 31 so I have to go back on Wednesday for another test, looks like a miscarriage x
The hospital has just called, my hcg is lower than they would like, it is only 31 so I have to go back on Wednesday for another test, looks like a miscarriage x
Cheeky_84
in
Fertility Network UK
3 years ago
Ruxolitinib and vaccine efficacy
Has anyone extracted anything useful from the blizzard of recent press coverage and small-scale studies with immunosuppressed individuals, about what exactly is the vaccine efficacy for those of us on Ruxolitinib? I am thoroughly confused and how safe I am now that I’ve been double vaccinated. Can our
Has anyone extracted anything useful from the blizzard of recent press coverage and small-scale studies with immunosuppressed individuals, about what exactly is the vaccine efficacy for those of us on Ruxolitinib? I am thoroughly confused and how safe I am now that I’ve been double vaccinated. Can our
Rob58
in
MPN Voice
3 years ago
How many days past transfer till Clear blue 3+
I’m 5 weeks today (hopefully🙏🏼) my clear blue tests still saying 2-3 weeks. How many days after transfer does it take to say 3+? I’m testing like a crazy person to make sure my hcg is rising. What does your hcg need to be at to get 3+?
I’m 5 weeks today (hopefully🙏🏼) my clear blue tests still saying 2-3 weeks. How many days after transfer does it take to say 3+? I’m testing like a crazy person to make sure my hcg is rising. What does your hcg need to be at to get 3+?
Hopedream
in
Fertility Network UK
3 years ago
Saxenda weight loss medication
I have myelofibrosis and take hydroxycarbamide. Can anyone tell me if there are any reasons why i should not have Saxenda which is a medicine to help you loose weight. Its a GLP1 hormone ( i understand) can anyone point me in the right direction. There are no drug interactions
I have myelofibrosis and take hydroxycarbamide. Can anyone tell me if there are any reasons why i should not have Saxenda which is a medicine to help you loose weight. Its a GLP1 hormone ( i understand) can anyone point me in the right direction. There are no drug interactions
Ginny70
in
MPN Voice
3 years ago
Progesterone drop, hcg rise 5 weeks plus 3 days - any ideas?
Hey everyone, so my low starting hcg has continued to double appropriately, but my progesterone level dropped a lot and Im trying to make sense of it - I had a fresh IVF blastocyst transfer with initially sky-high progesterone, have been on cyclogest 400mg three times a day, and and my Danish clinic
Hey everyone, so my low starting hcg has continued to double appropriately, but my progesterone level dropped a lot and Im trying to make sense of it - I had a fresh IVF blastocyst transfer with initially sky-high progesterone, have been on cyclogest 400mg three times a day, and and my Danish clinic
singleswimmer
in
Fertility Network UK
3 years ago
Captivate Trial MRD status
I've been part of the CAPTIVATE trial since 2018. My treatment ended in May 2019....Ibrutinib for 12 months and Venetoclax for 9. I just received several test results including Flow Citometry and I am still MRD negative after 2 years. This trial was simply awesome and a life saver. I was originally
I've been part of the CAPTIVATE trial since 2018. My treatment ended in May 2019....Ibrutinib for 12 months and Venetoclax for 9. I just received several test results including Flow Citometry and I am still MRD negative after 2 years. This trial was simply awesome and a life saver. I was originally
lamboman
in
CLL Support
3 years ago
CLL Research: Phase 2 CAPTIVATE Study Suggests Role for Fixed-Duration Treatment of CLL/SLL
https://cllpharmacist.com/cll-research-phase-2-captivate-study-suggests-role-for-fixed-duration-treatment-of-cll-sll/ The data in the uMRD cohort of this trial suggest that fixed-duration therapy is feasible in patients who achieve undetectable MRD (uMRD) status. The selection of durations for these
https://cllpharmacist.com/cll-research-phase-2-captivate-study-suggests-role-for-fixed-duration-treatment-of-cll-sll/ The data in the uMRD cohort of this trial suggest that fixed-duration therapy is feasible in patients who achieve undetectable MRD (uMRD) status. The selection of durations for these
WinJ3
in
CLL Support
3 years ago
Probiotics, MF and Ruxolitinib
Just something that came up while I was chatting briefly to my haematology nurse. I asked her if taking probiotics was a good idea for me, fully expecting her to say yes. However, it was a definite no, because my gut bacteria will not be the normal mixture. We didn't continue the conversation as she
Just something that came up while I was chatting briefly to my haematology nurse. I asked her if taking probiotics was a good idea for me, fully expecting her to say yes. However, it was a definite no, because my gut bacteria will not be the normal mixture. We didn't continue the conversation as she
Otterfield
in
MPN Voice
3 years ago
Weight gain with ruxolitinib
Hi can anyone help please? I've been on ruxolitinib since November and my weight is creeping up. I have always eaten well and exercise alot but this change is getting me down. If anyone has any advice I'd really appreciate it, thanks all x
Hi can anyone help please? I've been on ruxolitinib since November and my weight is creeping up. I have always eaten well and exercise alot but this change is getting me down. If anyone has any advice I'd really appreciate it, thanks all x
soomoo
in
MPN Voice
3 years ago
Chemical pregnancy but feeling more confused!?
Evening ladies, So Friday and Saturday faint positive tests. Sunday morning lighter, started to get cramps and bleeding and then clots today. Spoke to GP as clinic said can’t help as natural positive. GP said go A&E to be referred to EPU, they did pregnancy test and negative and then did bloods and
Evening ladies, So Friday and Saturday faint positive tests. Sunday morning lighter, started to get cramps and bleeding and then clots today. Spoke to GP as clinic said can’t help as natural positive. GP said go A&E to be referred to EPU, they did pregnancy test and negative and then did bloods and
BECIO
in
Fertility Network UK
3 years ago
5 weeks post FET, good HCG but mega headache
Hi, I’m 5 weeks 2 days with good beta tests however have developed the most cracking headache. I normally get this kind of headache before my period so terrified that something is very wrong. No bleeding and too early for scan which is scheduled in 12 days time.
Hi, I’m 5 weeks 2 days with good beta tests however have developed the most cracking headache. I normally get this kind of headache before my period so terrified that something is very wrong. No bleeding and too early for scan which is scheduled in 12 days time.
Snurf
in
Fertility Network UK
3 years ago
Low beta hcg 100 d14p5dt and spotting - looking for similar stories where this is not ectopic!
I am 14 days post a fresh blastocyst transfer and my hcg is low but rising (36 day 11, 72 day 13, and today 102 😐). I have some very mild occasional cramps and spotting, with some stringy blood stained mucus discharge (hope not TMI!). I assumed when the bleeding started after the initial low beta it
I am 14 days post a fresh blastocyst transfer and my hcg is low but rising (36 day 11, 72 day 13, and today 102 😐). I have some very mild occasional cramps and spotting, with some stringy blood stained mucus discharge (hope not TMI!). I assumed when the bleeding started after the initial low beta it
singleswimmer
in
Fertility Network UK
3 years ago
Is humira safe to take? Re potential lymphoma and leukemia?
Hi all. I am very new to this platform but so grateful to have a place to ask some difficult questions to people who may understand. I have just started humira after reacting badly to mabthera. I have also previously been on methotrexate, azaoress, nivaquin abd high dose steroids to name a few. I have
Hi all. I am very new to this platform but so grateful to have a place to ask some difficult questions to people who may understand. I have just started humira after reacting badly to mabthera. I have also previously been on methotrexate, azaoress, nivaquin abd high dose steroids to name a few. I have
lee2021
in
LUPUS UK
3 years ago
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