Experiences with

Chronic leukaemia

On 6 January 2025, the journal [i]BJ Haem[/i] published a review article titled [i]Management strategies for patients with lymphocytic leukaemia harbouring complex karyotype[/i] written by a team from Padua, Italy.

As chronic leukaemia progression is slower than acute, the symptom onset can be subtle and take years to have an impact on quality of life. Improving symptom awareness and early health seeking behaviour in the general population and targeted education for primary care clinicians may address this.

hi all a bit of a random question here I suppose My mother in law has chronic leukaemia (diagnosed 5 years ago) and wanting to go the all natural route, what would be the prognosis with no treatment?

Hi there, This month is my three year anniversary. After a number of blood tests l was told that l have Low Grade non Hodgkin's Lymphoma. (LGNH) well you know where the mind takes you from this point. In the three year period my WBC has been in the normal range for the most, and the lymphocytes count

Hello I want to update my story. In 2017, I was diagnosed with CLL and treated with Ibrutinib after six months. Eight months later, in 2018, I was diagnosed with two stage 1 breast tumors and another stage 2. During surgery, biopsies revealed Richter's Transformation, which was later shown to be pseudo-Richter's

Hi y’all. Been a while since I posted. Been feeling pretty good while on “wait & watch” since December of ‘22. My WBC was 21.8 then and my Abs Lymphocytes was 18. Now after more than 2 years, my WBC is 29 and my Abs Lymphocytes are 24.7. Again…..I feel good with no symptoms. However, my RDW

[/i] The full paper is a very thorough reference for those wanting to get a better understanding of what is currently understood about chronic lymphocytic leukemia and its treatment.

Hi, I’m 42yoa and have all the bad markers (17p, TP53, etc). Unfortunately, a week ago I was officially diagnosed with RT. I started showing symptoms a month ago and the nodes in my mediastinal area of chest are already 10.5cm large. Still waiting on PET scan to see severity but biopsy already confirmed

Just wanted to update you all about where I am with my CLL/MZL which transformed into DLBCL (still not sure if it’s Richters but definitely close) in January, 2025. I had 10 radiation treatments focused on the axial lump that was biopsied and which determined I had DLBCL, then 3 lympho depleting treatments

Financial Assistance for Patients with Chronic Lymphocytic Leukemia (CLL) & Small Lymphocytic Lymphoma (SLL) https://www.lls.org/support-resources/financial-support/co-pay-assistance-program If you are diagnosed with CLL or SLL, you may qualify for The Leukemia & Lymphoma Society's Co-Pay Assistance

Full Text (PDF) https://www.tandfonline.com/doi/epdf/10.1080/14796694.2025.2455926 [i]The original article, [/i][i]“Efficacy and safety in a 4-year follow-up of the ELEVATE-TN study comparing acalabrutinib with or without obinutuzumab versus obinutuzumab plus chlorambucil in treatment-naïve

[i] Abstract[/i] [i][/i] [i]The proliferation and survival of chronic lymphocytic leukemia (CLL) cells are heavily dependent on B-cell receptor (BCR) signaling and resistance to apoptosis.

[i][/i] [i]"Oral therapies targeting receptors in a blood cancer called chronic lymphocytic leukemia (CLL) have transformed outcomes with for those with this disease.

I’m new to this group chat, and found the information helpful. I see many people started increasing Vitamin D during the “wait and see” period. Is there a certain brand for vitamin C that’s better than others? Thank you!

Hi all, So I have been confirmed with CLL a week ago. I already had my first ever "deep" dental cleaning scheduled for mid April. I told my hematologist/oncologist about this and she said it's fine for me to a have it done and no need for antibiotics before or after since I'm not yet immunocompromised

Morning, we found out yesterday that my husband's CLL has transferred to Richter's Syndrome. He is having a lymph node biopsy and blood transfusion next week and starts chemo on Feb 28th. I've visited the Lymphoma Australia website, and the prognosis doesn't look good. Can anyone who has been through

Abstract report in New England Journal of Medicine Published February 5, 2025 No real new information here and I'm surprised anyone was recruited for this study as the control arm is chemoimmunotherapy and no account appears to have been taken for unmated IGHV or 17p/TP53 as the patients were

That long introduction brings me to the reason for this post, this article in Nature, brought to my attention by CLLerinOz https://www.nature.com/articles/s41375-024-02499-x From the abstract, with my emphasis; [i]The mutational status of immunoglobulin (IG) [/i][u][i]light chain genes [/i][/u][i]in chronic

Two studies presented exciting advancements in the treatment of chronic lymphocytic leukemia (CLL): Jennifer Brown, MD, PhD, presented findings that a novel, fixed-duration drug combination — consisting of a second-generation BTK inhibitor, called acalabrutinib, plus a BCL-2 inhibitor (venetoclax

I am currently on the watch and wait protocol. Yesterday was changed to stage 1 with swollen cervical lymph nodes. I would like to download the mentioned result tracking workbook. Thanks in advance.