Captivate Trial MRD status: I've been part of... - CLL Support

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Captivate Trial MRD status

lamboman profile image
15 Replies

I've been part of the CAPTIVATE trial since 2018. My treatment ended in May 2019....Ibrutinib for 12 months and Venetoclax for 9.

I just received several test results including Flow Citometry and I am still MRD negative after 2 years. This trial was simply awesome and a life saver.

I was originally diagnosed in 2013, my bone marrow was at some point 85% compromised. I was treatment naive when starting the trial.

I will try that drug combination again if I ever relapse.

Thanks to Dr Kipps, the science, big Pharma and the wonderful staff at UCSD Moore Cancer Center.

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lamboman
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15 Replies
Newdawn profile image
NewdawnAdministrator

Great news and long may it last for you! 👍

Do you want to restrict your post to this community in view of your identifiable avatar?

Newdawn

LovelyLilyGirl profile image
LovelyLilyGirl

Wonderful to hear. Very happy for you. I too am treated at UCSD Moore’s Cancer Center by Dr. Choi and reached uMRD in April 2021. Here’s to our long vacations from CLL. 🥂 Sally

annmcgowan profile image
annmcgowan

Great news. So pleased for you.Ann

Sushibruno profile image
Sushibruno

🥳🥳🥳🥳

SlowCLL profile image
SlowCLL

Good news, enjoy!

LeoPa profile image
LeoPa

You took them concurrently?

lamboman profile image
lamboman in reply to LeoPa

Yes. You start with Ibrutinib for 3 months and then they add Venetoclax.

LeoPa profile image
LeoPa in reply to lamboman

Thanks!

Smakwater profile image
Smakwater

OOh Aaaah Hey' lamboman!

That's how we want to hear it!

JM

Hoffy profile image
Hoffy

Great! And great trial! Hoffy

lamboman profile image
lamboman in reply to Hoffy

Hi Hoffy. Long time no see. How are you doing as you were in the trial one year earlier than me?

Hoffy profile image
Hoffy in reply to lamboman

Thanks , I am still UMRD after 3.25 years. I am doing well. So far so good! So lucky to be on the Captivate trial. I am glad you are doing well. Best wishes, Hoffy

SKINOW profile image
SKINOW

Looking back, would you have done this as "early treatment" back in 2014, 15, 16? I am now 3 years in, no symptoms, white count 30,000, lymph nodes growing and spleen increased by 50%. I am considering being in an early treatment trial taking ibrutinib.

lamboman profile image
lamboman in reply to SKINOW

I'm not an oncologist but I would have done this as early as possible to ensure the maximum chance of success. "watch & wait" was good for the chemo era but I don't think it makes sense anymore. Your CLL is not going to disappear but get worse over time. Why wait for treatment when we have amazing 90% plus success rate drug combination today that is certainly more effective as the disease is treated early on.

SKINOW profile image
SKINOW in reply to lamboman

THANKS

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