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Neuroendocrine prostate cancer could be restored to a state that responds to treatment
[i]It may be possible to restore drug-resistant neuroendocrine prostate cancer to a state that responds to treatment by depletion of a certain protein in cancer cells. A recent study published in Communications Biology by the University of Eastern Finland found that this protein, DPYSL5, is expressed
[i]It may be possible to restore drug-resistant neuroendocrine prostate cancer to a state that responds to treatment by depletion of a certain protein in cancer cells. A recent study published in Communications Biology by the University of Eastern Finland found that this protein, DPYSL5, is expressed
Don_1213
in
Advanced Prostate Cancer
7 months ago
BAM severe
I have been diagnosed with bile acid malabsorbtion after years of diahorea. I had a sehcat scan and was told my levels were less than 3 and I am in the severe category. I started treatment which is acid binding medication. These are sachets mixed in water and have helped the diahorea to settle most of
I have been diagnosed with bile acid malabsorbtion after years of diahorea. I had a sehcat scan and was told my levels were less than 3 and I am in the severe category. I started treatment which is acid binding medication. These are sachets mixed in water and have helped the diahorea to settle most of
Dor21
in
IBS Network
3 months ago
treatment side effects vs cancer side effects
”Pain” vs “discomfort” in abdomen region following radiation and on Lupron- is it side effects or the cancer itself? Dad was diagnosed November 2023 and received radiation for 5 weeks that ended Jan 3rd. Started Lupron end of November. Cancer has spread to part of hip bone and pelvic lymph nodes.
”Pain” vs “discomfort” in abdomen region following radiation and on Lupron- is it side effects or the cancer itself? Dad was diagnosed November 2023 and received radiation for 5 weeks that ended Jan 3rd. Started Lupron end of November. Cancer has spread to part of hip bone and pelvic lymph nodes.
alysona828
in
Advanced Prostate Cancer
7 months ago
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Iron deficiency
I was on iron tablets after blood tests the doctor said stop taking the pain tablets as they may be causing the problem but it wasn't it was my small intestine dying because I had the coeliac disease and ive not had a iron problem since being diagnosed coeliac. so if you've got a iron problem their
I was on iron tablets after blood tests the doctor said stop taking the pain tablets as they may be causing the problem but it wasn't it was my small intestine dying because I had the coeliac disease and ive not had a iron problem since being diagnosed coeliac. so if you've got a iron problem their
Bantamdyno
in
Restless Legs Syndrome
3 months ago
Information
Hi all. I have had some bad attacks over the last several months when I’m in a crowded place and it’s noisy, so much so that I’ve had to leave the building. I think I know what causes it having completed a first aid course in 1976 but just wondering if this has happened to anyone else. It’s like a panic
Hi all. I have had some bad attacks over the last several months when I’m in a crowded place and it’s noisy, so much so that I’ve had to leave the building. I think I know what causes it having completed a first aid course in 1976 but just wondering if this has happened to anyone else. It’s like a panic
paul456
in
Ataxia UK
2 months ago
heart palpitation from suboxome
Lately due to frequent cold I have to increase Buprenorphine and Naloxone to 1.5 mg sublingually (3 quarters of film (2 mg), then I have experienced horrendous heart palpitation and my heart rate goes down to 42 to 44 /minute. Even when I return to my previous dosage which is 1 mg (half film) sublingually
Lately due to frequent cold I have to increase Buprenorphine and Naloxone to 1.5 mg sublingually (3 quarters of film (2 mg), then I have experienced horrendous heart palpitation and my heart rate goes down to 42 to 44 /minute. Even when I return to my previous dosage which is 1 mg (half film) sublingually
halperinchen
in
Restless Legs Syndrome
4 months ago
Iron supplementation
Hi I have Hashimoto's - as yet untreated due to fluctuating TSH levels. My symptoms are numerous, and due to low levels of B12 and vitamin D, I am supplementing those. I am gluten Soy and Dairy free. My ferritin has been historically low and the GPs have frequently me prescribed Ferrous Fumarate.
Hi I have Hashimoto's - as yet untreated due to fluctuating TSH levels. My symptoms are numerous, and due to low levels of B12 and vitamin D, I am supplementing those. I am gluten Soy and Dairy free. My ferritin has been historically low and the GPs have frequently me prescribed Ferrous Fumarate.
Justine_Case
in
Thyroid UK
3 months ago
Bowel Problems...
Hello everyone, I think I already know the answer from other posts, so sorry for repeating, but I get so confused over the symptoms I get and I'd like to see what you think. I had a lap 15 years ago and was told I had adhesions between my uterus and bowel and I believe it was treated. I had two kids
Hello everyone, I think I already know the answer from other posts, so sorry for repeating, but I get so confused over the symptoms I get and I'd like to see what you think. I had a lap 15 years ago and was told I had adhesions between my uterus and bowel and I believe it was treated. I had two kids
LivvyCat
in
Endometriosis UK
3 months ago
Use hormone therapy or not with Proton therapy
Hi All, Question, doctor is suggesting hormone therapy along with proton therapy (28 treatments of radiation) my gleason score went from 3+3 to 4+3 last year and psa doubled from 10 to 20. I tried to get in to this study to determine the genetics of tumor but they said tumor sample was bad. should
Hi All, Question, doctor is suggesting hormone therapy along with proton therapy (28 treatments of radiation) my gleason score went from 3+3 to 4+3 last year and psa doubled from 10 to 20. I tried to get in to this study to determine the genetics of tumor but they said tumor sample was bad. should
jbsnv
in
Prostate Cancer Network
7 months ago
Ibs- C then sudden D. Any successes?
My issue is that I will be constipated for several days. Then at sudden moment, I have to go to the bathroom fast— like within a couple of minutes. And it will be total diarrhea for hours until I’m completely empty. Anyone else experience this? Any tips? it’s more pronounced when traveling. I’ll
My issue is that I will be constipated for several days. Then at sudden moment, I have to go to the bathroom fast— like within a couple of minutes. And it will be total diarrhea for hours until I’m completely empty. Anyone else experience this? Any tips? it’s more pronounced when traveling. I’ll
Senin
in
IBS Network
4 months ago
Chronic pain after prostatectomy
My friend had robotic prostatectomy in May 2019. In the almost 5 years since he has experienced daily abdominal pain. He has seen numerous doctors but none of them have been able to diagnose the source of the pain. He is an invalid due to this problem. Does anyone else know of a similar case? Any
My friend had robotic prostatectomy in May 2019. In the almost 5 years since he has experienced daily abdominal pain. He has seen numerous doctors but none of them have been able to diagnose the source of the pain. He is an invalid due to this problem. Does anyone else know of a similar case? Any
Sineah
in
Advanced Prostate Cancer
7 months ago
TruQap progress-lower TM
I posted about beginning this newly approved FDA drug in December. My blood tests last week showed that my TM dropped by 135 points. This is added to the Fulvestrant jabs I started around spring 2023. The combination seems to be going well so far. I was previously on Ibrance for several years until
I posted about beginning this newly approved FDA drug in December. My blood tests last week showed that my TM dropped by 135 points. This is added to the Fulvestrant jabs I started around spring 2023. The combination seems to be going well so far. I was previously on Ibrance for several years until
Yikes123
in
SHARE Metastatic Breast Cancer
7 months ago
Changing the name of cancer...would speed up research
I thought it wasn't something that had an impact, but thanks to the patience of an acquaintance of mine who works in clinical research, I finally understood the significance of what some newspapers (Italian and European, but maybe in the USA as well) are saying about the need to change the names of various
I thought it wasn't something that had an impact, but thanks to the patience of an acquaintance of mine who works in clinical research, I finally understood the significance of what some newspapers (Italian and European, but maybe in the USA as well) are saying about the need to change the names of various
Maxone73
in
Advanced Prostate Cancer
7 months ago
How can one person be so Lucky?
Diagnosed in December 2022 with Stage 4 metastatic PC Gleason 4 + 3, due to a PSMA Pet Scan. Highest my PSA got was 7.4, Pet Scan discovered a small spot on my T2 vertebrae that the MRI and bone scan did not find. I subsequently started on a regimen of Lupron and Erleada, adjusted to the SE and
Diagnosed in December 2022 with Stage 4 metastatic PC Gleason 4 + 3, due to a PSMA Pet Scan. Highest my PSA got was 7.4, Pet Scan discovered a small spot on my T2 vertebrae that the MRI and bone scan did not find. I subsequently started on a regimen of Lupron and Erleada, adjusted to the SE and
Condor77
in
Advanced Prostate Cancer
7 months ago
Cancer sufferer T3 below range, T4 50%, TSH 1.6 advice
Hello wise caring people. On one result, looks like they are a poor converter. My best pal is probably loosing battle with cancer - mid 60s male. He had radiation treatment on throat cancer 3 1/2 years ago. Treatment now stopped and has a lymph node node issue that is not responding, after throat
Hello wise caring people. On one result, looks like they are a poor converter. My best pal is probably loosing battle with cancer - mid 60s male. He had radiation treatment on throat cancer 3 1/2 years ago. Treatment now stopped and has a lymph node node issue that is not responding, after throat
Sleepman
in
Thyroid UK
7 months ago
anyone opted for Watch and Wait with indeterminate nodules thy3f? Looking for people with similar previous experience to make up my mind
hi everyone just wondering if anyone ever had the courage to opt for wait and see tactic with indeterminate nodules? How often did manage it? How did you feel in the end? What made you make that decision? my situation is that I have two indeterminate nodules on either side. Doctors recommended total
hi everyone just wondering if anyone ever had the courage to opt for wait and see tactic with indeterminate nodules? How often did manage it? How did you feel in the end? What made you make that decision? my situation is that I have two indeterminate nodules on either side. Doctors recommended total
Indianyellow
in
Thyroid UK
7 months ago
Patricia
Hi I'm a 3rd timer with BC. This time diagnosed June with stage 3 HER2+. Had surgery and chemo now on 3 weekly injections of Herceptin & 6monthly bone infusions and letrozole daily. Side effects fluctuate from day to day, fatigue, achey fluey, fuzzy head, indigestion, dizziness. In between I'm fine,
Hi I'm a 3rd timer with BC. This time diagnosed June with stage 3 HER2+. Had surgery and chemo now on 3 weekly injections of Herceptin & 6monthly bone infusions and letrozole daily. Side effects fluctuate from day to day, fatigue, achey fluey, fuzzy head, indigestion, dizziness. In between I'm fine,
ruskin10
in
My Breast Cancer Community
7 months ago
update on sore Nipple!
so did go to see the Dr who agreed my breasts were quite tricky to diagnose due to the amount of scar tissue from previous mammoplasty - initially felt the tenderness was maybe due to simple fibroadinoma but wasn’t certain - so I was fast tracked to Derriford and my appointment is this afternoon. Interestingly
so did go to see the Dr who agreed my breasts were quite tricky to diagnose due to the amount of scar tissue from previous mammoplasty - initially felt the tenderness was maybe due to simple fibroadinoma but wasn’t certain - so I was fast tracked to Derriford and my appointment is this afternoon. Interestingly
Sungolfer
in
PMRGCAuk
7 months ago
Heavy news today
Hi Everyone, I am feeling really bummed tonight…over the past 5 months I was on Enhertu, I qualified because of the destiny trials. Long story short it was a disaster, not only did I have infection after infection but I ended up with extensive uptake in bone Mets and spread to my liver again (originally
Hi Everyone, I am feeling really bummed tonight…over the past 5 months I was on Enhertu, I qualified because of the destiny trials. Long story short it was a disaster, not only did I have infection after infection but I ended up with extensive uptake in bone Mets and spread to my liver again (originally
SoulJourney
in
SHARE Metastatic Breast Cancer
7 months ago
Lower left abdominal and upper pelvic dull pain for 6 months
6 months ago while in the middle of a highly stressful situation, I developed a dull pain along the left rib line. Bowel movement at least once per day sometimes two times. The pain has subsided a few time. On vacation, during days off, and after a three day fast. I have journaled diet and activity and
6 months ago while in the middle of a highly stressful situation, I developed a dull pain along the left rib line. Bowel movement at least once per day sometimes two times. The pain has subsided a few time. On vacation, during days off, and after a three day fast. I have journaled diet and activity and
Arya2448
in
Pain Concern
5 months ago
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