I thought it wasn't something that had an impact, but thanks to the patience of an acquaintance of mine who works in clinical research, I finally understood the significance of what some newspapers (Italian and European, but maybe in the USA as well) are saying about the need to change the names of various types of cancer. And I must say, it would be a revolution of incredible magnitude.
I discovered that this has been discussed for years, but I hadn't heard about it. Essentially, the idea is to remove the tumor's origin from its name and instead use its molecular structure. For example, we could have a "BRCA positive cancer," regardless of whether it originated in the prostate or the breast. But what are the advantages? This is where I found myself thinking, "what the heck..." when I gave it some thought. Now, clinical trials are almost always conducted by tumor type according to its origin, so I could find myself in a situation where the same medication could be used for different tumors, which maybe are all BRCA positive, but the experimentation is planned to be carried out sequentially (e.g. first on prostate, then on breast, then colon...). Instead, according to the proposed new system, it would proceed in parallel based on the genetics of the tumor and not its origin.
Anyway, I wanted to share this with you! Also because it's one of those cases where I told myself, "how stupid are you?" for not having realized on my own the importance that this change would imply 😜😜
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Maxone73
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Wow that makes since! I always correlate certain drugs that work on for example breast cancer and others which are “HORMONE “ cancers. Thus those drugs could and are used for both but only if it passed clinical trials for that specific cancer.
From what I understood from my researcher friend and from what I have found online, that's exactly the problem. New name means you could recruit 200 patients (50 prostate, 50 breast, 50 colorectal and 50 lung for example) and do the trial on all of them simultaneously...now this is a time saver!
Honestly I do something similar to what you do, like taking a supplement that has been studied for another hormone driven cancer even if it's not prostate 😜
I take osterine when im on low T cycle and took it the whole year i was on ADT Orgo/daro and it helped so much. Osterine is in phase 3 for breast cancer and being fast tracked by FDA. Plus it has been used by body builders and athletes for ever. So we know the safety and concerns and dosages.
I thought about sarms as ostarine but I am worried because of bone metastasis, it promotes bone health when they are healthy, but I don’t know if it’s a good thing when there are cancer cells in the equation
I wish, if I had enough brain I would have carried on with my PhD, but it’s too stressful with all the deadlines. I admit I have tried to di some data analysis on data coming from patients, but even if they are anonymous you have no access without an institution behind you or data are too generic. Or maybe I have not found the right sources!
Yup, but the ones done with cancer patients that I have found do not specify if they were metastatic to the bone or not. Maybe I could try to research about a different sarm, newer ones should also have less side effects.
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