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Pre-CRPC Supplements/Drugs - Potential Risks vs Rewards?
With some substances there could be a "tipping" point depending on the substance, the dosage and the patient's stage of cancer where the substance may have a higher chance of having a negative effect instead of positive. It usually relates to ROS levels. Adequate levels of ROS are important for cancer
With some substances there could be a "tipping" point depending on the substance, the dosage and the patient's stage of cancer where the substance may have a higher chance of having a negative effect instead of positive. It usually relates to ROS levels. Adequate levels of ROS are important for cancer
jazj
in
Advanced Prostate Cancer
8 months ago
Not all Melatonin is alike ...
Study finds that melatonin content of supplements varies widely: "... in more than 71 percent of supplements ... the actual content rang[ed] from 83 percent less to 478 percent more than the concentration declared on the label ... Further analysis with mass spectrometry also found serotonin, a much
Study finds that melatonin content of supplements varies widely: "... in more than 71 percent of supplements ... the actual content rang[ed] from 83 percent less to 478 percent more than the concentration declared on the label ... Further analysis with mass spectrometry also found serotonin, a much
JackBruce2024
in
Cure Parkinson's
8 months ago
Daily depressive insomnia is killing me slowly..
Depression causing me to only sleep 3-4 hrs or less per night and is and has been affecting my entire life and has been going on for more than 2 years. I have no energy to do anything, I have lost interest in things I used to enjoy, exercise is extremely difficult and the daily headaches, dizziness
Depression causing me to only sleep 3-4 hrs or less per night and is and has been affecting my entire life and has been going on for more than 2 years. I have no energy to do anything, I have lost interest in things I used to enjoy, exercise is extremely difficult and the daily headaches, dizziness
Relaxman
in
Major Depressive Disorder (MDD) Support
8 months ago
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started my kid on ritalin
hi everyone, i started my son on Ritalin immediate release low dose 2.5mg twice a day, and noticed he’s having trouble sleeping at night. I even tried giving him a melatonin gummy, but it didn’t work. I was wondering if any parents out there could tell me what times worked best to administer the med
hi everyone, i started my son on Ritalin immediate release low dose 2.5mg twice a day, and noticed he’s having trouble sleeping at night. I even tried giving him a melatonin gummy, but it didn’t work. I was wondering if any parents out there could tell me what times worked best to administer the med
Mommywarrior4LC
in
CHADD's ADHD Parents Together
8 months ago
melatonin day 5
hey - merry Christmas everyone. Hoping everyone manages to find some serenity! Does anyone have any idea why melatonin is recommended to be taken on day 5 specifically on the period before ivf? I have a short period (2-3 days 4 at most and a 25 day cycle) wondering if I should take it slightly earlier
hey - merry Christmas everyone. Hoping everyone manages to find some serenity! Does anyone have any idea why melatonin is recommended to be taken on day 5 specifically on the period before ivf? I have a short period (2-3 days 4 at most and a 25 day cycle) wondering if I should take it slightly earlier
Cuppppatea
in
Fertility Network UK
8 months ago
Morning check in
Well the melatonin was a little bit of help bur still woke up every 2 hours ... talk to anxiety support contacted my doctor about using prescription sleep aid. He's starting me on trazadonne 50 MG..will take before bedtime any suggestions... also gonna get word search fill in books to help during
Well the melatonin was a little bit of help bur still woke up every 2 hours ... talk to anxiety support contacted my doctor about using prescription sleep aid. He's starting me on trazadonne 50 MG..will take before bedtime any suggestions... also gonna get word search fill in books to help during
jojo15210
in
Anxiety and Depression Support
8 months ago
About sleep problem in pregnancy
Hi ladies, hope you are fine. Anyone suffering sleep problems in early pregnancy? I am suffering insomnia and just 5 weeks running. My doctor recommended melatonin 3mg to regulate my sleep cycle? There are some controversy with melatonin.Anyone has taken this supplement while pregnant? Any other recommendations
Hi ladies, hope you are fine. Anyone suffering sleep problems in early pregnancy? I am suffering insomnia and just 5 weeks running. My doctor recommended melatonin 3mg to regulate my sleep cycle? There are some controversy with melatonin.Anyone has taken this supplement while pregnant? Any other recommendations
trishabhowmik
in
Fertility Network UK - Pregnancy Support
8 months ago
About sleep problem in pregnancy
Hi ladies, hope you are fine. Anyone suffering sleep problems in early pregnancy? I am suffering insomnia and just 5 weeks running. My doctor recommended melatonin 3mg to regulate my sleep cycle? There are some controversy with melatonin.Anyone has taken this supplement while pregnant? Any other recommendations
Hi ladies, hope you are fine. Anyone suffering sleep problems in early pregnancy? I am suffering insomnia and just 5 weeks running. My doctor recommended melatonin 3mg to regulate my sleep cycle? There are some controversy with melatonin.Anyone has taken this supplement while pregnant? Any other recommendations
trishabhowmik
in
Fertility Network UK
8 months ago
Covid sent me from managed hypo to hyper…
Hi all, I had been on 60mcg T3 & 25mcg levo, 6mg LDN for two years, managed hypothyroidism. Prior to this I presented with normal tsh, low T3, and normal T4. Vit d, B12, Ferratin, Folate all normal. I caught Covid in August and a week later started having severe symptoms of — insomnia, muscle
Hi all, I had been on 60mcg T3 & 25mcg levo, 6mg LDN for two years, managed hypothyroidism. Prior to this I presented with normal tsh, low T3, and normal T4. Vit d, B12, Ferratin, Folate all normal. I caught Covid in August and a week later started having severe symptoms of — insomnia, muscle
KettlebellQueen
in
Thyroid UK
8 months ago
Insomnia caused by neupro/rotigotine
Been taking neupro patches up to 8mg for 8 weeks now and from day one had significant issues with sleep. I normally would fall asleep and wake up 4 to 6 hours later. Now it's often just an hour later and im fully awake. Anyone else got this from their meds? Anyone else had an success in beating this?
Been taking neupro patches up to 8mg for 8 weeks now and from day one had significant issues with sleep. I normally would fall asleep and wake up 4 to 6 hours later. Now it's often just an hour later and im fully awake. Anyone else got this from their meds? Anyone else had an success in beating this?
Jefferami
in
Cure Parkinson's
8 months ago
Worsening insomnia can anyone help?
I’ve recently reduced my Levo dose because my T4 was 93% through the range and I was having palpitations. I was on 100mcg so now on 75mcg 4 times a week and 100mcg 3 times a week. Energy wise this is actually the best I’ve felt so far. Unfortunately the insomnia has worsened in the last few weeks where
I’ve recently reduced my Levo dose because my T4 was 93% through the range and I was having palpitations. I was on 100mcg so now on 75mcg 4 times a week and 100mcg 3 times a week. Energy wise this is actually the best I’ve felt so far. Unfortunately the insomnia has worsened in the last few weeks where
ockerdoc
in
Thyroid UK
8 months ago
2023: Your Successes and Failures
My mum is 83, has PD and dementia.
Successes
1. Constipation and digestive issues very much helped with the addition of Motilitone, a prokinetic. Once a day or every other day now. No strain. Zero stress around the issue now. Previously, there was a great deal. Abdominal pains have gone. (
My mum is 83, has PD and dementia.
Successes
1. Constipation and digestive issues very much helped with the addition of Motilitone, a prokinetic. Once a day or every other day now. No strain. Zero stress around the issue now. Previously, there was a great deal. Abdominal pains have gone. (
garygjs
in
Cure Parkinson's
8 months ago
How I keep my tinnitus at a manageable baseline
I have had tinnitus in both ears for around five years now and have had many spikes and have spent extended periods with 10/10 tinnitus but as of now fortunately and touchwood I haven’t had a significant spike in two and a half years and am at a manageable baseline. Getting tinnitus made be become hyperaware
I have had tinnitus in both ears for around five years now and have had many spikes and have spent extended periods with 10/10 tinnitus but as of now fortunately and touchwood I haven’t had a significant spike in two and a half years and am at a manageable baseline. Getting tinnitus made be become hyperaware
Kipp3
in
Tinnitus UK
8 months ago
Fibromyalgia or PMR
Hi, advice please! I had a PMR diagnosis so put on prednisone then rheumatologist diagnosis of not PMR but fibromyalgia so tapered off prednisone. Finished prednisone in Sept. Pains returned referred to physio which worsened Pains so was discharged. Got a appt with Dr finally but had a 6 week wait.
Hi, advice please! I had a PMR diagnosis so put on prednisone then rheumatologist diagnosis of not PMR but fibromyalgia so tapered off prednisone. Finished prednisone in Sept. Pains returned referred to physio which worsened Pains so was discharged. Got a appt with Dr finally but had a 6 week wait.
Monkey321
in
PMRGCAuk
8 months ago
Melatonin and bone loss / PCa
https://pubmed.ncbi.nlm.nih.gov/33452455/#:~:text=We%20also%20observed%20that%20melatonin,prevents%20cancer%2Dassociated%20osteoclast%20differentiation. -- in plain English, does this mean lower bone tumor initiation and/or progression? This next article is long and dense: https://erc.bioscientifica.com
https://pubmed.ncbi.nlm.nih.gov/33452455/#:~:text=We%20also%20observed%20that%20melatonin,prevents%20cancer%2Dassociated%20osteoclast%20differentiation. -- in plain English, does this mean lower bone tumor initiation and/or progression? This next article is long and dense: https://erc.bioscientifica.com
Derf4223
in
Advanced Prostate Cancer
9 months ago
Cancer and stress: not directly related to prostate cancer but interesting research
Being on melatonin and some chemical stuff to be able to sleep at night, I do not have anything intelligent to suggest to reduce our stress...apart maybe from sports/workouts if we can, whenever we can... https://www.nature.com/articles/s41591-023-02631-x
Being on melatonin and some chemical stuff to be able to sleep at night, I do not have anything intelligent to suggest to reduce our stress...apart maybe from sports/workouts if we can, whenever we can... https://www.nature.com/articles/s41591-023-02631-x
Maxone73
in
Advanced Prostate Cancer
9 months ago
Do Sulforaphane, Melatonin, and Cayenne Pepper work?
I've been a lurker for a while. First time post. I have had a radical prostatectomy, chemo (docetaxel - 6 infusions 3 weeks apart), radiation (38 doses) and Lupron (18 months). I am done with all treatment for now. PSA minimum was 0.02, now at 0.04. I've been reading a lot about sulforaphane (BROQ)
I've been a lurker for a while. First time post. I have had a radical prostatectomy, chemo (docetaxel - 6 infusions 3 weeks apart), radiation (38 doses) and Lupron (18 months). I am done with all treatment for now. PSA minimum was 0.02, now at 0.04. I've been reading a lot about sulforaphane (BROQ)
SisuMike
in
Advanced Prostate Cancer
9 months ago
Exemestane side effects?
With a great deal of effort, I managed to get my exemestane switched back to the original generic. I still have diarrhea, but not as extreme with the other generic. My oncologist thinks it is not the exemestane that is causing it. She says it is "not usual." It says it is a side effect of unknown frequency
With a great deal of effort, I managed to get my exemestane switched back to the original generic. I still have diarrhea, but not as extreme with the other generic. My oncologist thinks it is not the exemestane that is causing it. She says it is "not usual." It says it is a side effect of unknown frequency
TammyCross
in
SHARE Metastatic Breast Cancer
9 months ago
Anxiety Interfering with Daily Activities
Hello Everyone! I am new to the community and decided to reach out for support because I have really been struggling lately. I have had a really hard time maintaining any level of productivity these past few weeks. I recently upped my Sertraline dose so I know that it can take a bit for things to level
Hello Everyone! I am new to the community and decided to reach out for support because I have really been struggling lately. I have had a really hard time maintaining any level of productivity these past few weeks. I recently upped my Sertraline dose so I know that it can take a bit for things to level
ClassicalBlueKitty
in
Anxiety and Depression Support
9 months ago
short release vs fast release meds ??
hi there, I've been diagnosed earlier this year with moderate to severe adhd and generalised anxiety disorder. I was previously diagnosed with depression last year and had been on meds for that. I originally started on concerta on two different doses and felt that it made my anxiety so bad even
hi there, I've been diagnosed earlier this year with moderate to severe adhd and generalised anxiety disorder. I was previously diagnosed with depression last year and had been on meds for that. I originally started on concerta on two different doses and felt that it made my anxiety so bad even
tulipqueen
in
CHADD's Adult ADHD Support
9 months ago
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