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How To Make Melatonin Lotion : A More Efficient Way Of Getting Melatonin Compared To Oral Melatonin And A Surprise Finding
A major problem I see with oral melatonin is the very poor bioavailability of oral melatonin, thought to be around 3% in humans as discussed here : https://bmcpharmacoltoxicol.biomedcentral.com/articles/10.1186/s40360-016-0052-2#:~:text=Elimination%20half%2Dlives%20following%20oral,between%20the%20volunteers
A major problem I see with oral melatonin is the very poor bioavailability of oral melatonin, thought to be around 3% in humans as discussed here : https://bmcpharmacoltoxicol.biomedcentral.com/articles/10.1186/s40360-016-0052-2#:~:text=Elimination%20half%2Dlives%20following%20oral,between%20the%20volunteers
chartist
in
Cure Parkinson's
4 minutes ago
Strange, possibly hopeful realisation
This post mentions alternative remedies. Any evidence is anecdotal, based on my experience. Always check with your oncologist before using something they haven't prescribed. So, I am dealing with the second recurrence and looking at third line treatment. And wondering why my cancer (clear cell and
This post mentions alternative remedies. Any evidence is anecdotal, based on my experience. Always check with your oncologist before using something they haven't prescribed. So, I am dealing with the second recurrence and looking at third line treatment. And wondering why my cancer (clear cell and
candyapplegrey
in
My Ovacome
5 days ago
A Little More Tramadol?
Well, I found exactly ONE article discussing ONE patient (this case study was picked up by several medical publishers) in 2007 that they “guess” may have been suffering from Tramadol augmentation. Pardon my French, but what frickin idiots. They have this woman stop her years and years long use of tramadol
Well, I found exactly ONE article discussing ONE patient (this case study was picked up by several medical publishers) in 2007 that they “guess” may have been suffering from Tramadol augmentation. Pardon my French, but what frickin idiots. They have this woman stop her years and years long use of tramadol
DesertOasis
in
Restless Legs Syndrome
7 days ago
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Is There A Natural And Available Alternative To Fecal Microbiome Transplantation (FMT) ?
Since it looks like fecal microbiome transplantation (FMT) is not currently available to the masses, unless you you have C.diff, severe IBS, live in China or are able to find a trial and qualify for it. I have been wondering whether we have anything else at our disposal that might be able to offer a
Since it looks like fecal microbiome transplantation (FMT) is not currently available to the masses, unless you you have C.diff, severe IBS, live in China or are able to find a trial and qualify for it. I have been wondering whether we have anything else at our disposal that might be able to offer a
chartist
in
Cure Parkinson's
11 days ago
Introduction - RLS
I have been struggling with RLS for some time. There just doesn't seem to be anything that helps. Antihistamine medications only make it worse when I try to sleep. I have been prescribed sleep medication, but I am afraid to take it every night because I do not want to become dependent. Everything
I have been struggling with RLS for some time. There just doesn't seem to be anything that helps. Antihistamine medications only make it worse when I try to sleep. I have been prescribed sleep medication, but I am afraid to take it every night because I do not want to become dependent. Everything
DocCookie
in
Restless Legs Syndrome
15 days ago
Sleeping w/out THC for the first time in 5 years
I'm still trying to figure out several PD issues that I think are related to the estrogen patch I started about a year ago, and I intend to post about that eventually, but I wanted to give a quick update because my severe insomnia seems to be resolved. The last time I tried sleeping without THC was
I'm still trying to figure out several PD issues that I think are related to the estrogen patch I started about a year ago, and I intend to post about that eventually, but I wanted to give a quick update because my severe insomnia seems to be resolved. The last time I tried sleeping without THC was
1LittleWillow
in
Cure Parkinson's
16 days ago
Melatonin & Zoloft
Hi, has anyone taken melatonin and Zoloft together? And with daily low dose aspirin?
Hi, has anyone taken melatonin and Zoloft together? And with daily low dose aspirin?
Gratana
in
Major Depressive Disorder (MDD) Support
18 days ago
Correcting Mitochondrial Dysfunction
There are two interesting studies: 1. Melatonin 50mg per day corrects mitochondrial dysfunction and brings mitochondrial activity back to healthy control level in 3 months. 2. GlyNAC 100mg per kg per day corrects mitochondrial dysfunction and brings mitochondrial activity back to healthy control level
There are two interesting studies: 1. Melatonin 50mg per day corrects mitochondrial dysfunction and brings mitochondrial activity back to healthy control level in 3 months. 2. GlyNAC 100mg per kg per day corrects mitochondrial dysfunction and brings mitochondrial activity back to healthy control level
JayPwP
in
Cure Parkinson's
20 days ago
Bang for your buck
Supplements, medication, procedures Can someone tell me what supplements should be used with Parkinsons Among the various therapies that have shown at least some effect in the animal and/or human model are Carbadopa/Levadopa Actylcholine Actigal/Ursolic acid Adderil (amphetamine) Alcohol Alpha
Supplements, medication, procedures Can someone tell me what supplements should be used with Parkinsons Among the various therapies that have shown at least some effect in the animal and/or human model are Carbadopa/Levadopa Actylcholine Actigal/Ursolic acid Adderil (amphetamine) Alcohol Alpha
heartinmotion
in
Cure Parkinson's
21 days ago
Melatonin
Has anyone taken Melatonin for Anxiety in the TWW? Thanks 😊
Has anyone taken Melatonin for Anxiety in the TWW? Thanks 😊
Pineapple93
in
Fertility Network UK
22 days ago
melatonin advice for ivf please
so I’ve brought melatonin 5mg from biovea online (I’m in the uk.) I’m hoping to use the supplements to improve egg maturity. (My dheas and testosterone levels are already near optimal levels and I still continuously retrieve a poor number of mature eggs.) This is my very last cycle and I’m now desperate
so I’ve brought melatonin 5mg from biovea online (I’m in the uk.) I’m hoping to use the supplements to improve egg maturity. (My dheas and testosterone levels are already near optimal levels and I still continuously retrieve a poor number of mature eggs.) This is my very last cycle and I’m now desperate
Eat-sleep-ivf-repeat
in
Fertility Network UK
22 days ago
Lexapro and RLS
Has anyone with RLS started taking Lexapro for anxiety? If yes, did it have any affects on your RLS? My RLS is pretty well controlled at this time with minimal drugs (100 mg Gabapentin) after finally getting off Pramipexole. I also use Melatonin, Valarian Root, and CBN. But most helpful, I think,
Has anyone with RLS started taking Lexapro for anxiety? If yes, did it have any affects on your RLS? My RLS is pretty well controlled at this time with minimal drugs (100 mg Gabapentin) after finally getting off Pramipexole. I also use Melatonin, Valarian Root, and CBN. But most helpful, I think,
Crazilegs
in
Restless Legs Syndrome
27 days ago
I am so disappointed after having my first scan and only seen 5 follicles on day 6 of stimulating.
I am so disappointed after having my first scan and only seen 5 follicles on day 6 of stimulating. I am having my third IVF cycle in 6 months and already thinking of canceling. I was taking 900mg of COQ10 and 75mg of DHEA of 21century brand and Melatonin 3mg which brand I don't remember. Is 21 century
I am so disappointed after having my first scan and only seen 5 follicles on day 6 of stimulating. I am having my third IVF cycle in 6 months and already thinking of canceling. I was taking 900mg of COQ10 and 75mg of DHEA of 21century brand and Melatonin 3mg which brand I don't remember. Is 21 century
Nakijo
in
Fertility Network UK
1 month ago
Melatonin increases overall survival of prostate cancer patients with poor prognosis
Study outlines how melatonin can improve OS https://pubmed.ncbi.nlm.nih.gov/33110479/
Study outlines how melatonin can improve OS https://pubmed.ncbi.nlm.nih.gov/33110479/
kainasar
in
Fight Prostate Cancer
1 month ago
DAT Scan
I will be having a DAT Scan early next week. I am worried about the effects of the radioactive material which will be injected into me. Should I load up on Melatonin as a precaution? If yes, how much and when to take? Also I am told not to take C/L or any other medication for 48 hours before the scan
I will be having a DAT Scan early next week. I am worried about the effects of the radioactive material which will be injected into me. Should I load up on Melatonin as a precaution? If yes, how much and when to take? Also I am told not to take C/L or any other medication for 48 hours before the scan
JayPwP
in
Cure Parkinson's
1 month ago
Melatonin Seems To Outperform Three Common AD Drugs And Aerobic Exercise For AD In This New March 2024 Meta Analysis
In this new Systematic Review and Network Meta-Analysis, Melatonin appears to outperform Donanemab, Lecanemab, Aducanumab and aerobic Exercise in AD patients as discussed here : https://pubmed.ncbi.nlm.nih.gov/38461503/ Here is a relevant quote from the meta analysis :
' The analysis included 10
In this new Systematic Review and Network Meta-Analysis, Melatonin appears to outperform Donanemab, Lecanemab, Aducanumab and aerobic Exercise in AD patients as discussed here : https://pubmed.ncbi.nlm.nih.gov/38461503/ Here is a relevant quote from the meta analysis :
' The analysis included 10
chartist
in
Cure Parkinson's
2 months ago
Poor egg equality, day 3 tranfer, need advice/encouragement
Questions- poor egg quality, growth hormone, day 3 transfer, and PGT testing. Sorry for the long post but hoping for some advice/encouragement. After 1 year of infertility and 2 failed IUIs, I started banking embryos at age 32 (I'm in medical training and was worried about getting pregnant before my
Questions- poor egg quality, growth hormone, day 3 transfer, and PGT testing. Sorry for the long post but hoping for some advice/encouragement. After 1 year of infertility and 2 failed IUIs, I started banking embryos at age 32 (I'm in medical training and was worried about getting pregnant before my
nf2952
in
Fertility Network UK
2 months ago
Art64blue
Hello I am new to HealthUnlocked. I was prescribed Sertraline 50mg a month ago for Anxiety and Insomnia. I new with this drug that things would get worse before they get better but I have had awful side effects mostly increased anxiety and insomnia. I have read a lot of the experiences of being on Sertraline
Hello I am new to HealthUnlocked. I was prescribed Sertraline 50mg a month ago for Anxiety and Insomnia. I new with this drug that things would get worse before they get better but I have had awful side effects mostly increased anxiety and insomnia. I have read a lot of the experiences of being on Sertraline
Art64blue
in
Mental Health Support
2 months ago
Help me taper off 40 mg Prednisone sooner than 8 weeks
hi I had a uc flair then colonoscopy which showed I was inflamed in all colon. After the procedure symptoms worse, diagnosed with cdiff. So put on antibiotic, Vancomyacin, and prednisone 40 mg sir 7 days then step down by 5 mgs each week for 8 weeks. I am day 5 and symptoms improved want to taper
hi I had a uc flair then colonoscopy which showed I was inflamed in all colon. After the procedure symptoms worse, diagnosed with cdiff. So put on antibiotic, Vancomyacin, and prednisone 40 mg sir 7 days then step down by 5 mgs each week for 8 weeks. I am day 5 and symptoms improved want to taper
Yahtze
in
PMRGCAuk
2 months ago
Results and Advice Please
Hi There All, Seeking some expertise please. These are my latest test results taken via Medichecks (finger prick) February 19th; TSH 0.013 mIU/L (0.27 - 4.2) -6.5% Free T4 (fT4) 5.9 pmol/L (12 - 22) -61.0% Free T3 (fT3) 5.7 pmol/L (3.1 - 6.8) 70.3% T4:T3 Ratio 1.035 Thyroglobulin Antibodies (
Hi There All, Seeking some expertise please. These are my latest test results taken via Medichecks (finger prick) February 19th; TSH 0.013 mIU/L (0.27 - 4.2) -6.5% Free T4 (fT4) 5.9 pmol/L (12 - 22) -61.0% Free T3 (fT3) 5.7 pmol/L (3.1 - 6.8) 70.3% T4:T3 Ratio 1.035 Thyroglobulin Antibodies (
CDN_Lady
in
Thyroid UK
2 months ago
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