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Latest Pylarify clear with PSA at 4
I just had my 3rd PSMA-PET, and was relieved but surprised that it was totally clear. I had expected mets similar to my 1st one which was also run at a PSA of 4. BTW, the Axumin scan was clear at that time. I've been on an ADT/Zytiga vacation for about 18 months. My PSA did become undetectable for
I just had my 3rd PSMA-PET, and was relieved but surprised that it was totally clear. I had expected mets similar to my 1st one which was also run at a PSA of 4. BTW, the Axumin scan was clear at that time. I've been on an ADT/Zytiga vacation for about 18 months. My PSA did become undetectable for
V10fanatic
in
Advanced Prostate Cancer
1 year ago
Oligometastatic prostate cancer: Reality or figment of imagination?
New paper below, [1] full text. Oligometastatic PCa has been controversial from the start, with some denying that it exists. "If you have one met, you have many - you just can't see them." Then there is the counting problem. One study indicated that a few spinal mets visible on a bone scan were oligometastatic
New paper below, [1] full text. Oligometastatic PCa has been controversial from the start, with some denying that it exists. "If you have one met, you have many - you just can't see them." Then there is the counting problem. One study indicated that a few spinal mets visible on a bone scan were oligometastatic
pjoshea13
in
Fight Prostate Cancer
1 year ago
The Evolving Role of Diet in Prostate Cancer Risk and Progression
New paper below [1] - full text. I don't recall seeing the journal "
Current Opinion in Oncology
" before. "Recent data have further solidified the association between insulin resistance and prostate cancer ...". It's good to finally read that, although data to suggest it has been around for
New paper below [1] - full text. I don't recall seeing the journal "
Current Opinion in Oncology
" before. "Recent data have further solidified the association between insulin resistance and prostate cancer ...". It's good to finally read that, although data to suggest it has been around for
pjoshea13
in
Fight Prostate Cancer
1 year ago
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PSA rising during triplet therapy. What to ask the oncologist?
Hello to this wonderfully helpful community, my dad's initial PSA was extremely high (3103), so I don't know what to expect. The treatment has been going for four months and a half since ADT (2 months and a half since Zytiga and Docetaxel was added). He started ADT on December, Zytiga and Docetaxel
Hello to this wonderfully helpful community, my dad's initial PSA was extremely high (3103), so I don't know what to expect. The treatment has been going for four months and a half since ADT (2 months and a half since Zytiga and Docetaxel was added). He started ADT on December, Zytiga and Docetaxel
Sissel25
in
Advanced Prostate Cancer
1 year ago
ADT and paroxysmal afib
Are there risks having ADT with respect to paroxysmal afib
Are there risks having ADT with respect to paroxysmal afib
pd63
in
Advanced Prostate Cancer
1 year ago
test results
morning to all , I was just wondering about what I see on my test result My TSH apart from when I have, on a few occasions, reduced hormone treatment runs the same at 0.02 . With little change . Looking at my T4 it changes massively with from 20 sometimes 14 but looks like a see saw . Range
morning to all , I was just wondering about what I see on my test result My TSH apart from when I have, on a few occasions, reduced hormone treatment runs the same at 0.02 . With little change . Looking at my T4 it changes massively with from 20 sometimes 14 but looks like a see saw . Range
Gcart
in
Thyroid UK
1 year ago
Adding TurkeyTail (or other Mushrooms) to my current treatment
I'm a 70 year old, healthy person who has faced no major health issues (or addressed them quickly.) I'm retired and live alone. After pushing for PSA test, I had 6 in 6/22 and 20 in 8/22. Biopsy in 9/22 showed Gleason 4+5=9 and classified as stage 4. Bone scan and Cat showed small metastices in spine
I'm a 70 year old, healthy person who has faced no major health issues (or addressed them quickly.) I'm retired and live alone. After pushing for PSA test, I had 6 in 6/22 and 20 in 8/22. Biopsy in 9/22 showed Gleason 4+5=9 and classified as stage 4. Bone scan and Cat showed small metastices in spine
DoubleBlind
in
Advanced Prostate Cancer
1 year ago
Any tips for IVF with endometriosis?
Hello everyone 😊 So, after years of starting our fertility journey, we're finally doing our first cycle. It took a long time as we were first using NHS, and there was COVID, surgeries,etc etc. We're now working with a private clinic and we're now doing our first cycle of embryo batching (to accumulate
Hello everyone 😊 So, after years of starting our fertility journey, we're finally doing our first cycle. It took a long time as we were first using NHS, and there was COVID, surgeries,etc etc. We're now working with a private clinic and we're now doing our first cycle of embryo batching (to accumulate
happyseal
in
Fertility Network UK
1 year ago
Addition of Metastasis-Directed Therapy to Intermittent Hormone Therapy for Oligometastatic PC. The EXTEND Phase 2 Randomized Clinical Trial
MDT and intermittent ADT offer a progression free survival advantage when compared with intermittent ADT alone. "MDT facilitated a longer time with eugonadal testosterone as part of an intermittent hormone therapy strategy." "Time to new lesion failure was longer for patients randomized to combined
MDT and intermittent ADT offer a progression free survival advantage when compared with intermittent ADT alone. "MDT facilitated a longer time with eugonadal testosterone as part of an intermittent hormone therapy strategy." "Time to new lesion failure was longer for patients randomized to combined
tango65
in
Advanced Prostate Cancer
1 year ago
Amenorrhoea and endometriosis
Hi all, I wondered if any of you have/or know if it’s possible to have pain associated with endometriosis, whilst not (for the last 5m) having periods? I had excision surgery for uterosacral ligament and POD endo 6m ago, had one horrendous period 2 weeks later and nothing since. On no hormonal treatment
Hi all, I wondered if any of you have/or know if it’s possible to have pain associated with endometriosis, whilst not (for the last 5m) having periods? I had excision surgery for uterosacral ligament and POD endo 6m ago, had one horrendous period 2 weeks later and nothing since. On no hormonal treatment
Saffie123
in
Endometriosis UK
1 year ago
Your thoughts on getting off ADT while staying on AR inhibitor?
I often wonder why am i taking Orgovyx AND darolutamide especially since daro has the strongest binding to the androgen receptors than any of the other ari’s. What or how would normal T help if im blocking the Andro receptor anyway ? The only
three
things i can think of is: 1) Since darolutamide
I often wonder why am i taking Orgovyx AND darolutamide especially since daro has the strongest binding to the androgen receptors than any of the other ari’s. What or how would normal T help if im blocking the Andro receptor anyway ? The only
three
things i can think of is: 1) Since darolutamide
KocoPr
in
Advanced Prostate Cancer
1 year ago
Zoladex implant problem ?
Fellow travellers I reach out for your help experience and knowledge of having any problems following the Zoladex 12 week implant administration I had 6 monthly Zoladex and then decidesd to try the 12 week version. I had it 8 days ago and for the first time it bled and required 5 mins pressure to stop
Fellow travellers I reach out for your help experience and knowledge of having any problems following the Zoladex 12 week implant administration I had 6 monthly Zoladex and then decidesd to try the 12 week version. I had it 8 days ago and for the first time it bled and required 5 mins pressure to stop
SimMartin
in
Advanced Prostate Cancer
1 year ago
Why do we stop treatment
I have to post my experience of having once stopped treatment. I see various posts here with guys asking about stopping their treatments. I started treatment when I was 52 years old. ADT, Chemo and radiation. After treatment PSA went to undetectable. After 2 years with undetectable PSA I thought I was
I have to post my experience of having once stopped treatment. I see various posts here with guys asking about stopping their treatments. I started treatment when I was 52 years old. ADT, Chemo and radiation. After treatment PSA went to undetectable. After 2 years with undetectable PSA I thought I was
Islandboy2021
in
Advanced Prostate Cancer
1 year ago
Bipolar Androgen Therapy Followed by Androgen Receptor Inhibition as Sequential Therapy for Prostate Cancer
Here's a treat - a review of BAT (Bipolar Androgen Therapy), actually written by Dr. Sam Denmeade [1]. In his intro, he makes a point of stressing that androgen receptor axis therapies are "highly effective [i]
palliative
[/i] therapy, but they are
not curative
." A few years ago it was
Here's a treat - a review of BAT (Bipolar Androgen Therapy), actually written by Dr. Sam Denmeade [1]. In his intro, he makes a point of stressing that androgen receptor axis therapies are "highly effective [i]
palliative
[/i] therapy, but they are
not curative
." A few years ago it was
pjoshea13
in
Fight Prostate Cancer
1 year ago
Worrying study on long-term ADT (esp Enza)
I just came across a study (2019 International Journal of Pharmacology) that suggests that long-term use of ADT can cause neuroendicrine differentiation, leading to rapid spread and more aggressive spread. (the article was actually about the use of propanalol to counteract the effect of NED, but the
I just came across a study (2019 International Journal of Pharmacology) that suggests that long-term use of ADT can cause neuroendicrine differentiation, leading to rapid spread and more aggressive spread. (the article was actually about the use of propanalol to counteract the effect of NED, but the
CrocodileShoes
in
Advanced Prostate Cancer
1 year ago
PSA on ADT but post EBRT
Hi everyone! Just wondering if anyone has any info to share regarding psa after radiation but while still on adt. My dad who is stage T3b started Eligard in August 2022 (2 year course) followed by high dose brachytherapy in December and 23 sessions EBRT Dec-Jan 2023. His psa in Oct 2022 (pre-radiation
Hi everyone! Just wondering if anyone has any info to share regarding psa after radiation but while still on adt. My dad who is stage T3b started Eligard in August 2022 (2 year course) followed by high dose brachytherapy in December and 23 sessions EBRT Dec-Jan 2023. His psa in Oct 2022 (pre-radiation
ChloeSS
in
Advanced Prostate Cancer
1 year ago
NKX3.1 found in liver biopsy
The nkx3.1 was found in a recent liver biopsy. What does it tell the oncologist and what treatment would shrink the tumor ? Never heard of it and when looking it up it is confusing as it is in all prostate tumors from what I have read. They indicate it is a biomarker but how do you get rid of the tumor
The nkx3.1 was found in a recent liver biopsy. What does it tell the oncologist and what treatment would shrink the tumor ? Never heard of it and when looking it up it is confusing as it is in all prostate tumors from what I have read. They indicate it is a biomarker but how do you get rid of the tumor
Muffin2019
in
Advanced Prostate Cancer
1 year ago
Recently diagnosed- Stage 4 at 45 yrs old.
Hey all! I’m an active 45 year old Australian, dad of 10 and 12 year old, living in Vermont USA, and I just recently got diagnosed with stage 4 prostate cancer. Mets to lymph nodes, several vertebrea, hip, rib etc. Gleason 9 and a relatively low PSA at 6.7 which is unusual. Apparently the sign
Hey all! I’m an active 45 year old Australian, dad of 10 and 12 year old, living in Vermont USA, and I just recently got diagnosed with stage 4 prostate cancer. Mets to lymph nodes, several vertebrea, hip, rib etc. Gleason 9 and a relatively low PSA at 6.7 which is unusual. Apparently the sign
dochelem
in
Advanced Prostate Cancer
1 year ago
ART Radiation dose and ADT in localized PCa: a meta-regression of 5-year outcomes in phase III random control trials; 21,429 patients
I have had 21 months of ADT and also have decided to stop short of my suggested 24 months total treatment as of December, 2022; I cant take the low TET anymore and its consequent impacts. Just when I was doubting my choice to move to long term ADT (LTADT) after salvage radiation (sRT) I stumbled on this
I have had 21 months of ADT and also have decided to stop short of my suggested 24 months total treatment as of December, 2022; I cant take the low TET anymore and its consequent impacts. Just when I was doubting my choice to move to long term ADT (LTADT) after salvage radiation (sRT) I stumbled on this
RMontana
in
Active Surveillance - Prostate Cancer
1 year ago
[b]Enter the COMPASS Study[/b]
Enter the COMPASS Study here: https://malecare.org/compass-study/
Development and Validation of Sexual Quality of Life Questionnaire for Men-Who-Have-Sex-with-Men with Prostate Cancer The purpose of this study is to develop a sexual function survey specific for men who have sex with men (MSM
Enter the COMPASS Study here: https://malecare.org/compass-study/
Development and Validation of Sexual Quality of Life Questionnaire for Men-Who-Have-Sex-with-Men with Prostate Cancer The purpose of this study is to develop a sexual function survey specific for men who have sex with men (MSM
Darryl
Partner
in
Prostate Cancer Network
1 year ago
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