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More Evidence Linking ADT for PCa to Adverse Neurocognitive Effects -Meta-analysis shows increased risk of dementia, Parkinson's, depression
[i]As if we needed more reasons to dislike or avoid ADT, here is additional evidence of negative neurocognitive effects. This MedPage Today article will expecially be of special interest to those of us well into our "Golden Years" and on or considering ADT. [/i]
More Evidence Linking ADT for Prostate
[i]As if we needed more reasons to dislike or avoid ADT, here is additional evidence of negative neurocognitive effects. This MedPage Today article will expecially be of special interest to those of us well into our "Golden Years" and on or considering ADT. [/i]
More Evidence Linking ADT for Prostate
cujoe
in
Fight Prostate Cancer
7 months ago
given a choice about duration of ADT
Tall Allen and others. Clean PSMA, , 3+4, 3+4, and 4+3., biopsy. 77yrs old, hit gym daily but have significant side effects of lupron.. Being treated at Comprensive cancer center. Plan was one year of Lupron. After five SBRT, and nine months on adt, my doc is willing to let me terminate my Lupron
Tall Allen and others. Clean PSMA, , 3+4, 3+4, and 4+3., biopsy. 77yrs old, hit gym daily but have significant side effects of lupron.. Being treated at Comprensive cancer center. Plan was one year of Lupron. After five SBRT, and nine months on adt, my doc is willing to let me terminate my Lupron
Photographerhere
in
Prostate Cancer Network
7 months ago
Working with Stage IV
First time posting (be gentle) Anybody else still at work with the disease. I’ve contributed to a pension for 24 years, and with being diagnosed, am I being foolish staying at work. Note-minimum retirement is 58 at my work. Also, did read this right, ADT only gives about 10 mos. to 1 year increase
First time posting (be gentle) Anybody else still at work with the disease. I’ve contributed to a pension for 24 years, and with being diagnosed, am I being foolish staying at work. Note-minimum retirement is 58 at my work. Also, did read this right, ADT only gives about 10 mos. to 1 year increase
BigJ32
in
Advanced Prostate Cancer
7 months ago
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Are Lymph nodes a filter?
Do lymph nodes simply act as a temporary filter to prevent cancer from spreading too far? I was curious about this because I have 4th stage prostate cancer, and my Lymph had swelled to the size of a golfball. When I took the ADT, my PSA went from 1000, down to 6, and all evidence of cancer disappeared
Do lymph nodes simply act as a temporary filter to prevent cancer from spreading too far? I was curious about this because I have 4th stage prostate cancer, and my Lymph had swelled to the size of a golfball. When I took the ADT, my PSA went from 1000, down to 6, and all evidence of cancer disappeared
Aldo62
in
Advanced Prostate Cancer
7 months ago
Recovery of Testosterone
We all have heard about how long it takes to recover testosterone after you stop ADT. You probably also heard how age affects recovery time. The older you are the longer it takes and the T may never recover. The type of ADT you take can also affect recovery time - shot versus pill. I am 78 and I have
We all have heard about how long it takes to recover testosterone after you stop ADT. You probably also heard how age affects recovery time. The older you are the longer it takes and the T may never recover. The type of ADT you take can also affect recovery time - shot versus pill. I am 78 and I have
Mgtd
in
Prostate Cancer Network
7 months ago
Discussion about SHARE webinar: "Understanding Uterine Cancer Treatment Options" What would you like to learn more about?
For your convenience, here is the link: https://www.sharecancersupport.org/understanding-uterine-cancer-treatment-options-video/ Such a great presentation with lots information. I keep having to go back and look at it. It's one of the few webinars that even talk about my treatment option and talks
For your convenience, here is the link: https://www.sharecancersupport.org/understanding-uterine-cancer-treatment-options-video/ Such a great presentation with lots information. I keep having to go back and look at it. It's one of the few webinars that even talk about my treatment option and talks
Merma
Moderator
in
SHARE Uterine Cancer Support
7 months ago
Discussion about SHARE webinar: "Understanding Uterine Cancer Treatment Options" What would you like to learn more about?
https://www.sharecancersupport.org/understanding-uterine-cancer-treatment-options-video/ Such a great presentation with lots information. I keep having to go back and look at it. It's one of the few webinars that even talk about my treatment option and talks about combined hormone therapy. How do
https://www.sharecancersupport.org/understanding-uterine-cancer-treatment-options-video/ Such a great presentation with lots information. I keep having to go back and look at it. It's one of the few webinars that even talk about my treatment option and talks about combined hormone therapy. How do
Merma
Moderator
in
SHARE Uterine Cancer Support
7 months ago
Sciatica
I went off ADT 9 months ago after 6 months of Elegard depot treatment following prostate radiation. I know that many of the side effects of ADT can persist months and even years after stopping Elegard (Lupron). But I seem to have developed new symptoms (breast sensitivity and sciatica) 6 months after
I went off ADT 9 months ago after 6 months of Elegard depot treatment following prostate radiation. I know that many of the side effects of ADT can persist months and even years after stopping Elegard (Lupron). But I seem to have developed new symptoms (breast sensitivity and sciatica) 6 months after
sciaticaman
in
Advanced Prostate Cancer
7 months ago
Re: Weight lifting for ADT fat gain and weight gain
A huge thank you 🙏🏻 to everybody who posted comments for my son about lifting weights for weight gain/fat accumulation while on ADT . I sent them on and he did read them, and he called and told me that he was going to go that route and possibly higher a personal trainer too! Despite hiking just about
A huge thank you 🙏🏻 to everybody who posted comments for my son about lifting weights for weight gain/fat accumulation while on ADT . I sent them on and he did read them, and he called and told me that he was going to go that route and possibly higher a personal trainer too! Despite hiking just about
Cactus297
in
Advanced Prostate Cancer
7 months ago
Return of Armpit Odor - Yikes!!!
For almost two years, I (and others! 😃) have noticed the absence of male armpit odor. Attributable to full ADT (for metastatic PCa) and suppression of testosterone. (I'm on Triplet Therapy.) This morning I was surprised to notice odor for the first time since diagnosis. Due shortly for blood panel including
For almost two years, I (and others! 😃) have noticed the absence of male armpit odor. Attributable to full ADT (for metastatic PCa) and suppression of testosterone. (I'm on Triplet Therapy.) This morning I was surprised to notice odor for the first time since diagnosis. Due shortly for blood panel including
JohnInTheMiddle
in
Advanced Prostate Cancer
7 months ago
Estrogen vs ADT?
I've read 5 recent papers that discuss the use of estrogen as an alternative treatment to ADT (Lupron, etc.). The new data looks very favorable. A bit of history. Huggins discovered this effect around 1941-44, and he found that high doses of estrogen (estradiol) efficiently castrated men, which
I've read 5 recent papers that discuss the use of estrogen as an alternative treatment to ADT (Lupron, etc.). The new data looks very favorable. A bit of history. Huggins discovered this effect around 1941-44, and he found that high doses of estrogen (estradiol) efficiently castrated men, which
janebob99
in
Prostate Cancer Network
7 months ago
Age and timing for Triplet therapy?
I am age 81, active and neither fit nor frail, radiated in 2021 without hormone therapy. Radiated again in 2023 for a pelvic node. In December the PSA rose to 3.78 and a PSMA-PET scan showed cancer growing in prostate, shrinking in pelvic node, and spread to one abdominal node. I started ADT with
I am age 81, active and neither fit nor frail, radiated in 2021 without hormone therapy. Radiated again in 2023 for a pelvic node. In December the PSA rose to 3.78 and a PSMA-PET scan showed cancer growing in prostate, shrinking in pelvic node, and spread to one abdominal node. I started ADT with
vintage42
in
Advanced Prostate Cancer
7 months ago
perineural Invasion
My prostate biopsy has discovered perineural invasion (cancer along nerves) in 4 out of 6 sites with Gleason Score 9 in half of my prostate. This is associated with a significantly worse prognosis for survival. What are experiences of other men with this diagnosis? I am 84, in good health, and preparing
My prostate biopsy has discovered perineural invasion (cancer along nerves) in 4 out of 6 sites with Gleason Score 9 in half of my prostate. This is associated with a significantly worse prognosis for survival. What are experiences of other men with this diagnosis? I am 84, in good health, and preparing
Worked_the_World
in
Advanced Prostate Cancer
7 months ago
Statin use and mortality risk in men on ADT.
New ADT study from Hong Kong (1). "A total of 4920 patients were included, consisting of 2578 statin users and 2342 non-users (mean age 76.1 ± 8.2 years). Over a mean follow-up period of 4.2 ± 3.3 years, it was observed that statin users had significantly lower risks of both PCa-related mortality
New ADT study from Hong Kong (1). "A total of 4920 patients were included, consisting of 2578 statin users and 2342 non-users (mean age 76.1 ± 8.2 years). Over a mean follow-up period of 4.2 ± 3.3 years, it was observed that statin users had significantly lower risks of both PCa-related mortality
pca2004
in
Fight Prostate Cancer
7 months ago
My decision on Radiotherapy -v- Prostatectomy
I hope this story might be useful to others. I'm based in the UK and had a PSA of 12.7 from a test in June 2023. That led to an MRI in August with a PI-RADS of 5 with irregularity on the front of the prostate. I eventually had a biopsy at the end of September after 3 cancellations (this was through the
I hope this story might be useful to others. I'm based in the UK and had a PSA of 12.7 from a test in June 2023. That led to an MRI in August with a PI-RADS of 5 with irregularity on the front of the prostate. I eventually had a biopsy at the end of September after 3 cancellations (this was through the
MarkS
in
Prostate Cancer Network
7 months ago
The devil's dilemma
Between a rock and a hard place I am not sure if this topic has been discussed here before but it’s extremely frustrating to me since I don’t understand which way to go Very very interesting video. In a nut shell, the video discussion is about the introduction of NEPC and progression from HS to
Between a rock and a hard place I am not sure if this topic has been discussed here before but it’s extremely frustrating to me since I don’t understand which way to go Very very interesting video. In a nut shell, the video discussion is about the introduction of NEPC and progression from HS to
Ahk1
in
Advanced Prostate Cancer
7 months ago
PSA Risen in Last 6 months
Have been on here a week ago, explaining that my husband (who was diagnosed 10years ago) has now been diagnosed with Gastroporesis, so not eating much due to constant nausea and vomiting. We are due to see his Urologist in 2 weeks time, so had the dreaded PSA blood test. It had been almost undetectable
Have been on here a week ago, explaining that my husband (who was diagnosed 10years ago) has now been diagnosed with Gastroporesis, so not eating much due to constant nausea and vomiting. We are due to see his Urologist in 2 weeks time, so had the dreaded PSA blood test. It had been almost undetectable
Hidden
in
Advanced Prostate Cancer
7 months ago
After bicalutimide and a high testosterone level is pre treatment T just guess work?
Just turning to fellow travellers on our various journeys for some input/advice/ thoughts as I make a decision on how far to push to the SOC for my high risk G9, given my oncologist is saying 15 months adjuvant (I am nervous of anything less than 18 months) is enough given my co morbidities, age at 73
Just turning to fellow travellers on our various journeys for some input/advice/ thoughts as I make a decision on how far to push to the SOC for my high risk G9, given my oncologist is saying 15 months adjuvant (I am nervous of anything less than 18 months) is enough given my co morbidities, age at 73
SimMartin
in
Prostate Cancer Network
7 months ago
Divergent second opinion
My husband was recently diagnosed with PCa with 6-7 mets to the bones as seen on the PSMA Pet scan (see profile for details), The first MO we met at an NCCN center recommended triplet therapy. He has started Firmagon + Darulotomide with Docetaxel planned in the coming weeks. We also got a second opinion
My husband was recently diagnosed with PCa with 6-7 mets to the bones as seen on the PSMA Pet scan (see profile for details), The first MO we met at an NCCN center recommended triplet therapy. He has started Firmagon + Darulotomide with Docetaxel planned in the coming weeks. We also got a second opinion
Cali3
in
Advanced Prostate Cancer
7 months ago
New possible treatment being researched
Just read an interesting article about some research at Trent University that says there's hope for a new PCa treatment. It's a naturally occurring molecule called carnosine and seems to indicate much fewer side effects. As I've written before, I think ADT is too harsh and takes away too much, so I
Just read an interesting article about some research at Trent University that says there's hope for a new PCa treatment. It's a naturally occurring molecule called carnosine and seems to indicate much fewer side effects. As I've written before, I think ADT is too harsh and takes away too much, so I
Shamrock46
in
Advanced Prostate Cancer
7 months ago
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