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Androgens & colorectal cancer
Interesting new Swedish study below [1]. “To assess whether androgens play a role in explaining the sex related differences in the incidence of colorectal cancer (CRC).” According to the American Cancer Society: “Overall, the lifetime risk of developing colorectal cancer is about 1 in 23 for men
Interesting new Swedish study below [1]. “To assess whether androgens play a role in explaining the sex related differences in the incidence of colorectal cancer (CRC).” According to the American Cancer Society: “Overall, the lifetime risk of developing colorectal cancer is about 1 in 23 for men
pca2004
in
Fight Prostate Cancer
11 months ago
Struggling with ADT lack of libido
Hi everyone. I'm 48 and last June was diagnosed rare very aggressive stage IV cancer (salivary ducts), spread already to bones and lungs. I hope I can post here questions about ADT since there is not forum for my cancer type (too rare). I got 9 cycles of chemo, and after a break of two months and some
Hi everyone. I'm 48 and last June was diagnosed rare very aggressive stage IV cancer (salivary ducts), spread already to bones and lungs. I hope I can post here questions about ADT since there is not forum for my cancer type (too rare). I got 9 cycles of chemo, and after a break of two months and some
scale73
in
Advanced Prostate Cancer
11 months ago
OVM 200 clinical trial on TV
https://www.newscientist.com/article/2375922-advancing-immunology-the-future-of-vaccine-innovations/ at 6.25 mins is a bit of info about the trial I volunteered for. The ‘shout out’ is for ovarian cancers so I may not have had an immune response but I have heard nothing formally except last weeks scans
https://www.newscientist.com/article/2375922-advancing-immunology-the-future-of-vaccine-innovations/ at 6.25 mins is a bit of info about the trial I volunteered for. The ‘shout out’ is for ovarian cancers so I may not have had an immune response but I have heard nothing formally except last weeks scans
Brysonal
in
Fight Prostate Cancer
11 months ago
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ADT before and after IMRT
So my husband had 5 Cycles of Taxotere in 2019, was first line treatment, started Lupron fall of 2019, then PSA creeped up and MO started him on Casadex. Worked till 2022 when PSMA scan showed lymph nodes, started Zytiga in November 2022 , started with 44 Tomotherapy/IMRT in Feb 2023, My question is
So my husband had 5 Cycles of Taxotere in 2019, was first line treatment, started Lupron fall of 2019, then PSA creeped up and MO started him on Casadex. Worked till 2022 when PSMA scan showed lymph nodes, started Zytiga in November 2022 , started with 44 Tomotherapy/IMRT in Feb 2023, My question is
Keeper70
in
Prostate Cancer Network
11 months ago
My brother has advanced Prostate cancer
Hi everyone, I attached previous post about my brother. Since then he had one more PSA test which came back at 17! He has CT scan and bone scan, he had some new mets on his bones(spine) and they are suspected to some lymph nodes of chest. Currently he has hormone therapy every 3 months and Nubeqa
Hi everyone, I attached previous post about my brother. Since then he had one more PSA test which came back at 17! He has CT scan and bone scan, he had some new mets on his bones(spine) and they are suspected to some lymph nodes of chest. Currently he has hormone therapy every 3 months and Nubeqa
rasher1
in
Advanced Prostate Cancer
11 months ago
Optimal ADT length of time along with radiation for a recurrence 5 years post surgery-research or studies please.
I know there are folks on here that can put their fingers on this quicker than I. There was a gentleman in the prostate cancer support group that I facilitate last evening with a recurrence of Gleason 4 + 5 , five years post-surgery. Could you please provide me with research studies or data indicating
I know there are folks on here that can put their fingers on this quicker than I. There was a gentleman in the prostate cancer support group that I facilitate last evening with a recurrence of Gleason 4 + 5 , five years post-surgery. Could you please provide me with research studies or data indicating
wilcoxsaw
in
Advanced Prostate Cancer
11 months ago
42 yr old prostate cancer
I am looking for some relatable experiences. My husband was diagnosed with prostate cancer in February. He is 42 years old. His Gleason score was 9, PSA 17.8. He had surgery in March. He had multiple positive margins and one positive lymph node. He started hormone therapy 1 month prior to surgery. We
I am looking for some relatable experiences. My husband was diagnosed with prostate cancer in February. He is 42 years old. His Gleason score was 9, PSA 17.8. He had surgery in March. He had multiple positive margins and one positive lymph node. He started hormone therapy 1 month prior to surgery. We
Footballlover
in
Advanced Prostate Cancer
11 months ago
Adjuvant ADT
Hi everybody, this is the first time I post on (any) PC-forum. I can honestly tell you, for me you are a great support! Thank you! I am 76 years (now). Quite fit. May 2021 I was diagnosed with Gleason 9 PC. Tumor was slightly outside the prostate, but no metastasis. Got ADT (june 2021) and two weeks
Hi everybody, this is the first time I post on (any) PC-forum. I can honestly tell you, for me you are a great support! Thank you! I am 76 years (now). Quite fit. May 2021 I was diagnosed with Gleason 9 PC. Tumor was slightly outside the prostate, but no metastasis. Got ADT (june 2021) and two weeks
Nomiskneh
in
Prostate Cancer Network
11 months ago
2 years into Stage 4 Treatment
Hello all, I’m writing for some help regarding my dad. 2 years ago he was diagnosed prostate adenocarcinoma Gleason 5+4 with PSA 146 and Mets to ischium, sacrum and one rib. He started on Zytiga, Lupron and Prednisone and received 20 treatments of radiation to a cumulative dose of 60 Gy. Overall
Hello all, I’m writing for some help regarding my dad. 2 years ago he was diagnosed prostate adenocarcinoma Gleason 5+4 with PSA 146 and Mets to ischium, sacrum and one rib. He started on Zytiga, Lupron and Prednisone and received 20 treatments of radiation to a cumulative dose of 60 Gy. Overall
petdoc
in
Advanced Prostate Cancer
11 months ago
How is thyroid hormone prescribed across the US?
I suspect there might be a few comments on this just-posted thread: [i]Matt Ettleson[/i] [i]Ed: @NorthwesternU[/i] [i]/@NUFeinbergMed[/i] [i]. Former resident/CMR @UMIntMed[/i] [i]. Clinical Instructor @uchicagomed[/i] [i]. Focus: improving care of thyroid disease.[/i] [i]Chicago, IL[/i] [i]1h
I suspect there might be a few comments on this just-posted thread: [i]Matt Ettleson[/i] [i]Ed: @NorthwesternU[/i] [i]/@NUFeinbergMed[/i] [i]. Former resident/CMR @UMIntMed[/i] [i]. Clinical Instructor @uchicagomed[/i] [i]. Focus: improving care of thyroid disease.[/i] [i]Chicago, IL[/i] [i]1h
helvella
Thyroid UK
in
Thyroid UK
11 months ago
PTEN loss is not a determinant of time to castration-resistance following androgen-deprivation therapy in prostate cancer
Abdallah Alzoubi 1 2 , Samir Al Bashir 3 , Aya Smairat 4 , Ahmad Alrawashdeh 5 , Husam Haddad 6 , Khalid Kheirallah 7 Affiliations PMID: 37305830 PMCID: PMC10251393 DOI: 10.25122/jml-2023-0034 Free PMC article Abstract Androgen deprivation therapy (ADT) remains the principal
Abdallah Alzoubi 1 2 , Samir Al Bashir 3 , Aya Smairat 4 , Ahmad Alrawashdeh 5 , Husam Haddad 6 , Khalid Kheirallah 7 Affiliations PMID: 37305830 PMCID: PMC10251393 DOI: 10.25122/jml-2023-0034 Free PMC article Abstract Androgen deprivation therapy (ADT) remains the principal
Magnus1964
in
Advanced Prostate Cancer
11 months ago
End of holiday??
Hi everybody, was wondering if you could share your experiences to help me decide the end of my ADT holiday. In short: PCA found in 10/2019, PSA=49, Gleason=8, mets in local + infra/para aortal lymph nodes, started ADT 11/2019, radiotherapy 01/2020, undetectable PSA 09/2020, started holiday 05/2022
Hi everybody, was wondering if you could share your experiences to help me decide the end of my ADT holiday. In short: PCA found in 10/2019, PSA=49, Gleason=8, mets in local + infra/para aortal lymph nodes, started ADT 11/2019, radiotherapy 01/2020, undetectable PSA 09/2020, started holiday 05/2022
R1166
in
Advanced Prostate Cancer
11 months ago
Need help to fight fatigue from Radium 223
Stage 4 for last 3 years. Had 6 cycles of Chemo and then Abiraterone for 18+ months until it stopped being effective. Currently part of trial with Radium 223. Had 4 cycles already and 2 more to go. After this will likely have to switch to Enzalutamide and ADT. Now having bad fatigue issues; on scale
Stage 4 for last 3 years. Had 6 cycles of Chemo and then Abiraterone for 18+ months until it stopped being effective. Currently part of trial with Radium 223. Had 4 cycles already and 2 more to go. After this will likely have to switch to Enzalutamide and ADT. Now having bad fatigue issues; on scale
Ronnie7C
in
Advanced Prostate Cancer
11 months ago
PSMA PET Scan Shows no mets?!
I have/had Stage 4, Gleason 8/9 prostate cancer now for 2 years. 5 mets including 4 rib and 1 shoulder blade. Possible lymph node involvement. Went on Lupron and Zytiga. Radiation of prostate after 8 months of ADT. I've had now 4 PET scans. The latest was yesterday, as reported below. It says
I have/had Stage 4, Gleason 8/9 prostate cancer now for 2 years. 5 mets including 4 rib and 1 shoulder blade. Possible lymph node involvement. Went on Lupron and Zytiga. Radiation of prostate after 8 months of ADT. I've had now 4 PET scans. The latest was yesterday, as reported below. It says
groth12345
in
Advanced Prostate Cancer
11 months ago
2 Questions
Background: 45 yo, athletic with no comorbidities. Gleason 9, metastatic with 5 bone mets, node mets, and BRCA2. No surgeries or radiation. I’ve been on ADT since Jan 30, 2023. PSA at time of first Firmagon shot was 78. one month later it at 2nd shot it was 5. On Mar 1, 2023 it was 1.5. started Zytiga
Background: 45 yo, athletic with no comorbidities. Gleason 9, metastatic with 5 bone mets, node mets, and BRCA2. No surgeries or radiation. I’ve been on ADT since Jan 30, 2023. PSA at time of first Firmagon shot was 78. one month later it at 2nd shot it was 5. On Mar 1, 2023 it was 1.5. started Zytiga
revchris77
in
Advanced Prostate Cancer
11 months ago
Anyone have a high testosterone after SBRT?
In September 2022 I had image guided SBRT utilizing ViewRay Technology for a 3+4 gleason grade, low decipher score, PSA 2.7 before treatment, on Avodart for BPH. Been monitoring PSAs and Testosterone every three months, and remaining on Avodart. During this time my PSAs and Testosterone values have
In September 2022 I had image guided SBRT utilizing ViewRay Technology for a 3+4 gleason grade, low decipher score, PSA 2.7 before treatment, on Avodart for BPH. Been monitoring PSAs and Testosterone every three months, and remaining on Avodart. During this time my PSAs and Testosterone values have
Yearofthecow
in
Prostate Cancer Network
11 months ago
Enhertu next treatment??
I have been posting a lot lately. Thank you everyone for all your help. Some history…..I have lobular MBC. I have Mets in stomach lining, liver, and hip bone. got almost a year and a half from ibrance. After that I was on Exemestane and Everolimus for 2 months and all my liver mets grew. My
I have been posting a lot lately. Thank you everyone for all your help. Some history…..I have lobular MBC. I have Mets in stomach lining, liver, and hip bone. got almost a year and a half from ibrance. After that I was on Exemestane and Everolimus for 2 months and all my liver mets grew. My
Ticket123
in
SHARE Metastatic Breast Cancer
11 months ago
Blood Test Result
After being on ADT for two weeks, my blood test shows my Testosterone to be 109 (low). I guess this is the goal of ADT, to lower my Testosterone. However, in the same test result, the following was flagged as either low or high. Can my ADT attributed to the issues flagged by the test result? RBC
After being on ADT for two weeks, my blood test shows my Testosterone to be 109 (low). I guess this is the goal of ADT, to lower my Testosterone. However, in the same test result, the following was flagged as either low or high. Can my ADT attributed to the issues flagged by the test result? RBC
toyman79912
in
Advanced Prostate Cancer
11 months ago
Requesting Help to Develop Bespoke BAT
Brief history. Diagnosed in July 2020 with oligometastatic PC with PSA 1,600… picked at 13,000+ after biopsy, Gleason 8. One previous bone femur lesion ( succesfuly treated by SBRT and 3 pelvic lymphodes (succesfuly treated by Lu-177). Discordance and previous existence of FDG+/PSMA- lesions. Volume
Brief history. Diagnosed in July 2020 with oligometastatic PC with PSA 1,600… picked at 13,000+ after biopsy, Gleason 8. One previous bone femur lesion ( succesfuly treated by SBRT and 3 pelvic lymphodes (succesfuly treated by Lu-177). Discordance and previous existence of FDG+/PSMA- lesions. Volume
CurrentSEO
in
Fight Prostate Cancer
11 months ago
Requesting Help to Develop Bespoke BAT Protocol
Brief history. Diagnosed in July 2020 with oligometastatic PC with PSA 1,600… picked at 13,000+ after biopsy, Gleason 8. One previous bone femur lesion ( succesfuly treated by SBRT and 3 pelvic lymphodes (succesfuly treated by Lu-177). Discordance and previous existence of FDG+/PSMA- lesions. Volume
Brief history. Diagnosed in July 2020 with oligometastatic PC with PSA 1,600… picked at 13,000+ after biopsy, Gleason 8. One previous bone femur lesion ( succesfuly treated by SBRT and 3 pelvic lymphodes (succesfuly treated by Lu-177). Discordance and previous existence of FDG+/PSMA- lesions. Volume
CurrentSEO
in
Advanced Prostate Cancer
11 months ago
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