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What next?
RP in Sept. 2014 with salvage radiation May-June 2015. Focal radiation to spot on T-5 in November 2019. Not on ADT and u ndetectable PSA until April 2021. Rising since then and now at 1.6. Results of a PYL Pet scan last week are: IMPRESSION: 1. Since August 2, 2016, new PSMA avid left paraesophageal
RP in Sept. 2014 with salvage radiation May-June 2015. Focal radiation to spot on T-5 in November 2019. Not on ADT and u ndetectable PSA until April 2021. Rising since then and now at 1.6. Results of a PYL Pet scan last week are: IMPRESSION: 1. Since August 2, 2016, new PSMA avid left paraesophageal
Mjex
in
Advanced Prostate Cancer
2 years ago
ADT does it kill or only shrink cancer cells?
Has anyone seen a clinical study on this?
Has anyone seen a clinical study on this?
Scout4answers
in
Advanced Prostate Cancer
2 years ago
MRI 3T results
This looks pretty damn good. Not sure if I am reading this right but it appears they can not find my cancer any more and my Prostate has shrunk from 150cc to 74cc. "PI-RADS 2 - Low probability of cancer (Clinically significant cancer is unlikely to be present)" My MRI in July 21 was rated PI-RADS -5.
This looks pretty damn good. Not sure if I am reading this right but it appears they can not find my cancer any more and my Prostate has shrunk from 150cc to 74cc. "PI-RADS 2 - Low probability of cancer (Clinically significant cancer is unlikely to be present)" My MRI in July 21 was rated PI-RADS -5.
Scout4answers
in
Advanced Prostate Cancer
2 years ago
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Need for Cystoscopy?
Quick recap of my situation: RP in Sep 2019 for G9 w/SVI, LN+, and high risk Decipher. RT 8 months later along with 24 mth ADT (just finished). About 2 months ago, I noticed a drop of blood coming from my uretha at the tip of my penis. My urologist ordered a CAT scan (which was clean) and cystoscopy
Quick recap of my situation: RP in Sep 2019 for G9 w/SVI, LN+, and high risk Decipher. RT 8 months later along with 24 mth ADT (just finished). About 2 months ago, I noticed a drop of blood coming from my uretha at the tip of my penis. My urologist ordered a CAT scan (which was clean) and cystoscopy
DJBUNK
in
Advanced Prostate Cancer
2 years ago
Gut microbiome and prostate cancer
The U.S. government is overseeing a dozen or so RCTs pertaining to gut microbiome and prostate cancer. A few of them: To Investigate the Role of Gut Microbiome in ADT Related Metabolic Changes in Prostate Cancer Patients - Full Text View - ClinicalTrials.gov https://clinicaltrials.gov/ct2/show/NCT04687709
The U.S. government is overseeing a dozen or so RCTs pertaining to gut microbiome and prostate cancer. A few of them: To Investigate the Role of Gut Microbiome in ADT Related Metabolic Changes in Prostate Cancer Patients - Full Text View - ClinicalTrials.gov https://clinicaltrials.gov/ct2/show/NCT04687709
Hidden
in
Advanced Prostate Cancer
2 years ago
Can a case be made for ADT vacation during a 4week radiation therapy?
I would like your opinions. It seem to me it might make the prostate cells more radiosenitive because they are dividing faster. I think I’d feel better during the Rad rx and would restart after Rad rx finished . On orgovx and zytiga. Bad idea? Don’t know? Go ahead? What do you think?
I would like your opinions. It seem to me it might make the prostate cells more radiosenitive because they are dividing faster. I think I’d feel better during the Rad rx and would restart after Rad rx finished . On orgovx and zytiga. Bad idea? Don’t know? Go ahead? What do you think?
nuc1111
in
Advanced Prostate Cancer
2 years ago
Feedback Needed - ADT to begin!
Original Biopsy Stats [2/5/21] and then I procrastinated...I'm not enthusiastic at this point... Gleason 4+3 and 3+3 cores pos: 4 PSA: 13.8 [then] > now 25 PSA Density .34 Clinical state cT1C I've signed up for SBRT...Kaiser NCal. Dr. Mohan 5 treatment sessions@15 min each. Gold anchors, Prior to the
Original Biopsy Stats [2/5/21] and then I procrastinated...I'm not enthusiastic at this point... Gleason 4+3 and 3+3 cores pos: 4 PSA: 13.8 [then] > now 25 PSA Density .34 Clinical state cT1C I've signed up for SBRT...Kaiser NCal. Dr. Mohan 5 treatment sessions@15 min each. Gold anchors, Prior to the
trregan
in
Prostate Cancer And Gay Men
2 years ago
Small molecule, big potential for treating prostate cancer
Another idea out of left field, one of these kind of ideas is going to unlock the answer to keeping cancer from progressing . Then we will have the luxury of dying of old age. MIT News | Massachusetts Institute of Technology Small molecule, big potential for treating prostate cancer MIT researchers
Another idea out of left field, one of these kind of ideas is going to unlock the answer to keeping cancer from progressing . Then we will have the luxury of dying of old age. MIT News | Massachusetts Institute of Technology Small molecule, big potential for treating prostate cancer MIT researchers
Scout4answers
in
Advanced Prostate Cancer
2 years ago
ARASENS: Darolutamide + ADT + Docetaxel may become new SOC for mHSPC - from ASCO GU Symposium 2022
Dr. Matthew R Smith of Mass Gen. CC, reported significant overall survival from 3 ARASENS trial results when compared to placebo + ADT + Docetaxel. A 32% reduction in the risk of death with no increased toxicity (pub. in NEJofM and wrap-up edition of ASCO GU 2022 Symposium). With such dramatic results
Dr. Matthew R Smith of Mass Gen. CC, reported significant overall survival from 3 ARASENS trial results when compared to placebo + ADT + Docetaxel. A 32% reduction in the risk of death with no increased toxicity (pub. in NEJofM and wrap-up edition of ASCO GU 2022 Symposium). With such dramatic results
JRPnSD
in
Advanced Prostate Cancer
2 years ago
ALT (SGPT) - 5X normal limits - Concerning? Mets to liver lungs and bones
Hello everyone, Just want to give an update on my dad (69) has mets to the bones, liver, lungs and pelvic lymph nodes, PSA 113, Gleason 4+5 upon diagnosis back in July 2021. He started Firmagon and then on Zoladex and then 6 cycles of docetaxel which finished at the end of November. His mets in general
Hello everyone, Just want to give an update on my dad (69) has mets to the bones, liver, lungs and pelvic lymph nodes, PSA 113, Gleason 4+5 upon diagnosis back in July 2021. He started Firmagon and then on Zoladex and then 6 cycles of docetaxel which finished at the end of November. His mets in general
dch1953
in
Advanced Prostate Cancer
2 years ago
Neoadjuvant ADT - is a slowing PSA drop rate normal?
Hi all, first time poster here. My father (61, very healthy) was DX'd Sept 2021 with high-risk locally advanced prostate cancer with the following profile: G9, pre-op PSA ~58, MRI showing 1 possible pelvic LN mets. He had no symptoms and it came out of nowhere during his check up. From the treatment
Hi all, first time poster here. My father (61, very healthy) was DX'd Sept 2021 with high-risk locally advanced prostate cancer with the following profile: G9, pre-op PSA ~58, MRI showing 1 possible pelvic LN mets. He had no symptoms and it came out of nowhere during his check up. From the treatment
sixmongoos
in
Advanced Prostate Cancer
2 years ago
ADT collagen/cartilage issues
Taking a pole I’m in my 4th year of ADT (eligard/Zytiga) and my joints are weaker..most Achilles issues. now both my eyes are affected..vitriol membrane humour separation leaving me with dancing Weiss ring floaters disrupting my field if vision. I’m quite myopic so they tell me it’s a risk factor. Wonder
Taking a pole I’m in my 4th year of ADT (eligard/Zytiga) and my joints are weaker..most Achilles issues. now both my eyes are affected..vitriol membrane humour separation leaving me with dancing Weiss ring floaters disrupting my field if vision. I’m quite myopic so they tell me it’s a risk factor. Wonder
Jbooml
in
Advanced Prostate Cancer
2 years ago
Dad's end of journey
Hi all, as I started the journey with my dad in this forum 4 years ago,I think it was worthy to finish it here as well, taking a moment to thank all of you that helped me to go through this journey and find the best treatments for my dad. My dad was more than 3 years on ADT + Zytiga+ Prednisone and his
Hi all, as I started the journey with my dad in this forum 4 years ago,I think it was worthy to finish it here as well, taking a moment to thank all of you that helped me to go through this journey and find the best treatments for my dad. My dad was more than 3 years on ADT + Zytiga+ Prednisone and his
Noel91
in
Advanced Prostate Cancer
2 years ago
Estradiol?
Has anyone taken a low dose Estradiol along with ADT? If so, any benefits or harm?? Thank you all!!!
Has anyone taken a low dose Estradiol along with ADT? If so, any benefits or harm?? Thank you all!!!
JolleySprings
in
Advanced Prostate Cancer
2 years ago
VERU-111 (sabizabulin)
I was just reading about the very positive findings for sabizabulin in treating Covid-19 and remembered that several members had been in early clinical trials for prostate cancer (under the name VERU-111). https://fortune.com/2022/04/12/experimental-covid-drug-sabizabulin/ The reason it may work for
I was just reading about the very positive findings for sabizabulin in treating Covid-19 and remembered that several members had been in early clinical trials for prostate cancer (under the name VERU-111). https://fortune.com/2022/04/12/experimental-covid-drug-sabizabulin/ The reason it may work for
Tall_Allen
in
Advanced Prostate Cancer
2 years ago
HAs anyone tried BODY by SCIENCE workouts or Blood Flow Restriction training to maintain muscle and bone density ?
I’m six months into ADT with Orgovyx and Zytiga and I’m losing muscle fast?
I’m six months into ADT with Orgovyx and Zytiga and I’m losing muscle fast?
PBnative
in
Advanced Prostate Cancer
2 years ago
ADT & the gut microbiome.
New study from Japan below [1]. Not good, & presumably worse for the more efficient Abiraterone than Lupron, say. First, some terms: (a) "The α- and ß-diversity of gut microbiota" alpha diversity pertains to richness/variety beta diversity is based on a before-after comparison (b) "microbiota" versus
New study from Japan below [1]. Not good, & presumably worse for the more efficient Abiraterone than Lupron, say. First, some terms: (a) "The α- and ß-diversity of gut microbiota" alpha diversity pertains to richness/variety beta diversity is based on a before-after comparison (b) "microbiota" versus
pjoshea13
in
Advanced Prostate Cancer
2 years ago
Career after PCa diagnosis?
I've been working for a large company as an IT employee. But, after being PCa diagnosed and all the treatments involved, especially the mind-bending ADT drugs, the quick thinking, swift information sweeping, memory recall and overall mental acuity seems challenged to say the least. So, I've finally
I've been working for a large company as an IT employee. But, after being PCa diagnosed and all the treatments involved, especially the mind-bending ADT drugs, the quick thinking, swift information sweeping, memory recall and overall mental acuity seems challenged to say the least. So, I've finally
DarkEnergy
in
Advanced Prostate Cancer
2 years ago
PSA rising while on ADT mono therapy
After 4 years of being hormone sensitive PSA is rising now while on single ADT (Zoladex). Is this when I become castrate resistant. What are the symptoms confirming this. Do you need testosterone to rise as well as the PSA to confirm castrate resistant. I asked for PET scan but might not be approved
After 4 years of being hormone sensitive PSA is rising now while on single ADT (Zoladex). Is this when I become castrate resistant. What are the symptoms confirming this. Do you need testosterone to rise as well as the PSA to confirm castrate resistant. I asked for PET scan but might not be approved
Islandboy2021
in
Advanced Prostate Cancer
2 years ago
Yet another new member...
Just introducing myself at the prompt of this website... I'm 62 now, and after having my prostate removed via Davinci, the nice folk who examine such stuff have pronounced that I am a stage 4a cancer patient. I apparently have lymph node mets, but none (yet) to bones or further in the body. Currently
Just introducing myself at the prompt of this website... I'm 62 now, and after having my prostate removed via Davinci, the nice folk who examine such stuff have pronounced that I am a stage 4a cancer patient. I apparently have lymph node mets, but none (yet) to bones or further in the body. Currently
chickgreen
in
Advanced Prostate Cancer
2 years ago
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