Inherited aggressive pc

[pd63]

Dad diagnosed mid 60s after emergency admittance as he couldn't piss, had prostate removed and radiotherapy, presumably to pelvic area etc. but not sure, he died 15 yrs later with advanced pc. Brother had psa of 10 at age 59 and dre revealed some abnormality, biopsy revealed pc and he had 20 sessions EBRT and no ADT, no problems after, that was 12 years ago, he can't remember his gleason score and has lost his biopsy report.

I've been diagnosed favourable intermediate risk.

Obviously it's in the genes, is there increased risk of aggressive pc

[FMOH_N]

My recommendation is to take action, and seriously follow up and don´t delay treatment if needed. what about Genomic testing? wishing you best of luck and health.

[Tall_Allen]

No. While partially heritable, the aggressiveness is not. I know a man whose brother is metastatic, but he has been successfully doing active surveillance for the last 10 years.

[pd63 in reply to Tall_Allen]

Thks for that I'm coming up to my repeat tp biopsy in October, 1st repeat after diagnosis last year just getting a bit stressed I think, not about the procedure, but the possible outcome, natural to be stressed I suppose.

I'm keeping fingers crossed and will stay on AS if no progression found

[HopingForTheBest1]

I had genetic testing, which found BRCA2 mutation. This made me susceptible to aggressive PC, which I do have. Needed to be very proactive with this. Get 2nd opinions, research, and participate in support groups both online and in person.

[LandManager]

It may make sense to get genomic test to see if your genes show a propensity for prostate cancer, and perhaps have your children get the test. Prostate cancer treatment side effects can be nasty. Perhaps you should get treatment, but if so, get the treatment that has the side effects that you can live with the easiest. A study shows that for folks like you, all treatments, including watchful waiting, have the same cancer survival rating after 15 years.