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Experiences with
Androgen deprivation therapy (ADT)
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I am livid, confused , worried and scared as hell that my ORGOVYX -ADT symptoms are mine for life.
what is the difference of being on
-Orgovyx for life and having the exact same symptoms off the drug but caused by the low testosterone you acquired off the drug and by taking the drug.
what is the difference of being on
-Orgovyx for life and having the exact same symptoms off the drug but caused by the low testosterone you acquired off the drug and by taking the drug.
JWS13
in
Advanced Prostate Cancer
10 months ago
RISING PSA 2 YEARS POST EBRT/ADT
Two years post EBRT plus 6 months
ADT
. Meeting with Oncologist in a few weeks and am wondering what he is going to make of the following PSA progression.
Two years post EBRT plus 6 months
ADT
. Meeting with Oncologist in a few weeks and am wondering what he is going to make of the following PSA progression.
Waldo13
in
Prostate Cancer Network
1 year ago
Survey!
So, I and other members can get an idea on how you feel about
vacation(s). Please just answer YES if you think they’re okay, or NO, if you think they’re not.
So, I and other members can get an idea on how you feel about
vacation(s). Please just answer YES if you think they’re okay, or NO, if you think they’re not.
j-o-h-n
in
Advanced Prostate Cancer
10 months ago
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Treatment Decision: Now considering surgery
Brachy's full recommendation is to start
ADT
immediately, then surgery, then EBRT and continuance of
ADT
up to 24 months in total. To be clear he is not saying lets do surgery and see where your PSA goes afterwards but rather surgery, 6 weeks of recovery and then EBRT all the while staying on
ADT
.
Brachy's full recommendation is to start
ADT
immediately, then surgery, then EBRT and continuance of
ADT
up to 24 months in total. To be clear he is not saying lets do surgery and see where your PSA goes afterwards but rather surgery, 6 weeks of recovery and then EBRT all the while staying on
ADT
.
CavScout
in
Advanced Prostate Cancer
6 months ago
Sleep while taking Xtandi and Adt
Hello everyone, I am sure that this has been discussed on here before, I was unable to find any post to answer my question . I am taking Xtandi ( aprox 16 months) Lupron, I had chemo. My latest PSA was less then <0.01. It has been there for over a year now. ( See my profile for my journey.) My
Hello everyone, I am sure that this has been discussed on here before, I was unable to find any post to answer my question . I am taking Xtandi ( aprox 16 months) Lupron, I had chemo. My latest PSA was less then <0.01. It has been there for over a year now. ( See my profile for my journey.) My
JD-guy
in
Advanced Prostate Cancer
10 months ago
Understanding the Threat of Micrometastases (also known as Minimal Residual Disease) in Prostate Cancer or Don't sweat the small stuff
From the article: It has been shown that
ADT
can eliminate bone marrow micrometastasis in approximately 80% of patients [173, 174]. So, when undergoing treatment, patients are attacking micrometastases and eliminating them... It is why there is an oligometastatic state.
From the article: It has been shown that
ADT
can eliminate bone marrow micrometastasis in approximately 80% of patients [173, 174]. So, when undergoing treatment, patients are attacking micrometastases and eliminating them... It is why there is an oligometastatic state.
NPfisherman
in
Fight Prostate Cancer
3 months ago
mCRPC end of ADT--staying the course.
My dad saw his oncologist yesterday. My sister and I were there; we both read “Being Mortal” and watched several videos on the subject. The MO brought in the PSA test and said it was time to start considering a treatment change and the next steps were chemo and there was also Pluvicto. What happened
My dad saw his oncologist yesterday. My sister and I were there; we both read “Being Mortal” and watched several videos on the subject. The MO brought in the PSA test and said it was time to start considering a treatment change and the next steps were chemo and there was also Pluvicto. What happened
lgutman
in
Advanced Prostate Cancer
1 month ago
Celebrex and Curcumin and Magnesium.
I take 20 mg of atorvastatin which I just started when I started
adt
. No libido at all. Some weight gain. Energy pretty good for a guy going on 74. This has been a long road and I must give credit to my Lord and Savior Jesus Christ for the strength to endure and answer to prayers.
I take 20 mg of atorvastatin which I just started when I started
adt
. No libido at all. Some weight gain. Energy pretty good for a guy going on 74. This has been a long road and I must give credit to my Lord and Savior Jesus Christ for the strength to endure and answer to prayers.
Professorgary
in
Advanced Prostate Cancer
3 months ago
Does testosterone fluctuate after ADT ends?
But for the past 2-3 weeks, I am once more unable to get an erection and my libido has vanished once again as if I was still on
ADT
.
But for the past 2-3 weeks, I am once more unable to get an erection and my libido has vanished once again as if I was still on
ADT
.
Mascouche
in
Advanced Prostate Cancer
10 months ago
My own PSA values over time: 70% drop in just 3 months on Dutasteride and no ADT
That's a 70% decrease in PSA, with no
therapy! Dutasteride decreases
DHT
levels by more then 90%, which is why there is such a dramatic decrease in PSA levels.
DHT
is the fuel that feeds prostate cancer growth, not testosterone.
That's a 70% decrease in PSA, with no
therapy! Dutasteride decreases
DHT
levels by more then 90%, which is why there is such a dramatic decrease in PSA levels.
DHT
is the fuel that feeds prostate cancer growth, not testosterone.
janebob99
in
Prostate Cancer Network
6 months ago
Is creatine safe?
Hi all after 37 radiation sessions I started back on weight training 3 times a week.I was also on
ADT
for 24 months.I’m 70 and my Gleason scale was 8 my PSA is now totally ok.I finished
ADT
9 months ago and am only just feeling glimmerings of libido.Does anyone have any knowledge as to if it’s safe to
Hi all after 37 radiation sessions I started back on weight training 3 times a week.I was also on
ADT
for 24 months.I’m 70 and my Gleason scale was 8 my PSA is now totally ok.I finished
ADT
9 months ago and am only just feeling glimmerings of libido.Does anyone have any knowledge as to if it’s safe to
Coggeshall
in
Prostate Cancer Network
1 year ago
Long complicated paper on gut microbiome and PCa, human and mouse studies.
bacteria-derived molecule leakage (endotoxemia) ultimately contributing to chronic inflammation12,13,14. ” “In the present study we found a systematic reduction in gut microbiota diversity correlating with increasing PCa volume and aggressiveness in two distinct clinical scenarios of patients without
ADT
bacteria-derived molecule leakage (endotoxemia) ultimately contributing to chronic inflammation12,13,14. ” “In the present study we found a systematic reduction in gut microbiota diversity correlating with increasing PCa volume and aggressiveness in two distinct clinical scenarios of patients without
ADT
Graham49
in
Advanced Prostate Cancer
4 months ago
Very low psa with new bone mets
He was diagnosed 4 years ago with oligometastatic pca,went through radiation,
adt
+abirateron and chemo. In some point abirateron has failed so went for chemo,one year later when psa is still low as 0.014 new bone metastases popped up on pet psma scan.
He was diagnosed 4 years ago with oligometastatic pca,went through radiation,
adt
+abirateron and chemo. In some point abirateron has failed so went for chemo,one year later when psa is still low as 0.014 new bone metastases popped up on pet psma scan.
Niso
in
Advanced Prostate Cancer
19 days ago
High Potassium Levels?
Specifically Radiation and
ADT
. Hubby has dangerously high potassium levels, he has kidney disease so this is something that is watched. We even log all of our food and the Nephrologist is baffled by it-he doesn’t eat anything to cause such a spike.
Specifically Radiation and
ADT
. Hubby has dangerously high potassium levels, he has kidney disease so this is something that is watched. We even log all of our food and the Nephrologist is baffled by it-he doesn’t eat anything to cause such a spike.
USAFproudmom
in
Fight Prostate Cancer
10 months ago
Addition of an ARSI to standard ADT significantly increases the risk of fractures and falls in men with prostate cancer
Jones C, Gray S, Brown M, et al. Risk of fractures and falls in men with advanced or metastatic prostate cancer receiving androgen deprivation therapy and treated with novel androgen receptor signalling inhibitors: a systematic review and meta-analysis of randomised controlled trials. Eur Urol Oncol.
Jones C, Gray S, Brown M, et al. Risk of fractures and falls in men with advanced or metastatic prostate cancer receiving androgen deprivation therapy and treated with novel androgen receptor signalling inhibitors: a systematic review and meta-analysis of randomised controlled trials. Eur Urol Oncol.
Graham49
in
Advanced Prostate Cancer
5 months ago
High-Dose Transdermal Estradiol as ADT
Does anyone have any experience with this? According to my understanding: It's not FDA approved, but used here in the U.S., and all over the rest of the world. It's at least as effective in lowering T to castrate levels. It carries a far more tolerable profile of SEs than LHRH drugs, presumably
Does anyone have any experience with this? According to my understanding: It's not FDA approved, but used here in the U.S., and all over the rest of the world. It's at least as effective in lowering T to castrate levels. It carries a far more tolerable profile of SEs than LHRH drugs, presumably
Horse12888
in
Advanced Prostate Cancer
10 months ago
Salvage Brachytherapy
Current PSA is 0.02 on eligard,abi and pred….last psma showed only one area of active cancer(psa 18 at that time prior to
ADT
).
Current PSA is 0.02 on eligard,abi and pred….last psma showed only one area of active cancer(psa 18 at that time prior to
ADT
).
Tommyj2
in
Advanced Prostate Cancer
3 months ago
De-escalation
I am working with my own MO on de-escalation so no
ADT
injection for me at the end of September and so am on the Apalutamide monotherapy. ( only been a couple of weeks). Will report my QOL situation plus any change to. My PSA which has been undetectable for 14 months.
I am working with my own MO on de-escalation so no
ADT
injection for me at the end of September and so am on the Apalutamide monotherapy. ( only been a couple of weeks). Will report my QOL situation plus any change to. My PSA which has been undetectable for 14 months.
Brysonal
in
Fight Prostate Cancer
10 months ago
Low hemoglobin, and foot neuropathy common with ADT?
I was on Lupon for six months, three years ago and experienced feet going numb mostly at night and low hemoglobin. Those issues subsided once stopping Lupron for a few months. These symptoms became more acute during the last two years on Orgovyx with hemoglobin dropping to 9. ( I also had four
I was on Lupon for six months, three years ago and experienced feet going numb mostly at night and low hemoglobin. Those issues subsided once stopping Lupron for a few months. These symptoms became more acute during the last two years on Orgovyx with hemoglobin dropping to 9. ( I also had four
SViking
in
Advanced Prostate Cancer
9 months ago
Husband has passed
He was never in pain since he started
ADT
. He became extremely weak, fatigued and only wanted to sleep…23 out of 24 hrs. When he was awake, tho, he had such beautiful humor.
He was never in pain since he started
ADT
. He became extremely weak, fatigued and only wanted to sleep…23 out of 24 hrs. When he was awake, tho, he had such beautiful humor.
Hidden
in
Advanced Prostate Cancer
9 months ago
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