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Experiences with
Androgen deprivation therapy (ADT)
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Duration of ADT
Started
ADT
and abiraterone then 4m later pelvic RT. PSA still undetectable and Testosterone <2. The original plan was for 2 years of
ADT
and AA. At ESMO 2021 Dr. Attard suggested that SOC should be 3 years of
ADT
for patients falling into this and similar locally advanced subsets.
Started
ADT
and abiraterone then 4m later pelvic RT. PSA still undetectable and Testosterone <2. The original plan was for 2 years of
ADT
and AA. At ESMO 2021 Dr. Attard suggested that SOC should be 3 years of
ADT
for patients falling into this and similar locally advanced subsets.
hg115pb
in
Advanced Prostate Cancer
Initial RP or RT and salvage comparisons?
Thus, it follows many RT patients have only
ADT
as salvage, and
ADT
not considered curative as is a successful salvage treatment. So, since yes salvage RT readily available for surgery patients, do RP patients overall during their lifetimes endure less time on
ADT
than do those men who choose
ADT
?
Thus, it follows many RT patients have only
ADT
as salvage, and
ADT
not considered curative as is a successful salvage treatment. So, since yes salvage RT readily available for surgery patients, do RP patients overall during their lifetimes endure less time on
ADT
than do those men who choose
ADT
?
maley2711
in
Advanced Prostate Cancer
Adt
Anybody quit
adt
against medical advice because of quality of life issues? Thanks
Anybody quit
adt
against medical advice because of quality of life issues? Thanks
nuc1111
in
Advanced Prostate Cancer
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ADT and heart mitral valve regurgitation.
Can this be caused by my
ADT
treatments? Is it reversible? I never had this before I started
ADT
. Thanks
Can this be caused by my
ADT
treatments? Is it reversible? I never had this before I started
ADT
. Thanks
Ahk1
in
Advanced Prostate Cancer
Orchiectomy or ADT
Do I have an Orchiectomy or use
ADT
medications. from what I have read, Orchiectomy has shown to have better result than
ADT
in terms of long term survival plus it is a lot cheaper than paying indefinitely for
ADT
drugs and may have less health issues.
Do I have an Orchiectomy or use
ADT
medications. from what I have read, Orchiectomy has shown to have better result than
ADT
in terms of long term survival plus it is a lot cheaper than paying indefinitely for
ADT
drugs and may have less health issues.
old64horn
in
Advanced Prostate Cancer
PSADT is 6 months
I will most likely start
ADT
or
ADT
+. Recommendation are welcomed.
I will most likely start
ADT
or
ADT
+. Recommendation are welcomed.
old64horn
in
Advanced Prostate Cancer
Prostate Cancer Foundation : ADT: What You Really Need to Know .. "Who should not get ADT? "
"Who should not get
ADT
? Anybody else with prostate cancer. If you just have a rising PSA after radiation therapy or radical prostatectomy, that is not a good enough reason for a doctor to put you on
ADT
.
"Who should not get
ADT
? Anybody else with prostate cancer. If you just have a rising PSA after radiation therapy or radical prostatectomy, that is not a good enough reason for a doctor to put you on
ADT
.
George71
in
Advanced Prostate Cancer
Effect on Hair of Ending ADT
I am one month away from completing a 24 month
ADT
treatment plan. During that time, my wife tells me that my hair has considerably thicken over my previously bald spot. It's still pretty thin, but not nearly as much as it was before I started
ADT
.
I am one month away from completing a 24 month
ADT
treatment plan. During that time, my wife tells me that my hair has considerably thicken over my previously bald spot. It's still pretty thin, but not nearly as much as it was before I started
ADT
.
DJBUNK
in
Advanced Prostate Cancer
Overall survival (OS) & (MFS) in men with biochemical relapse (BCR) after radical prostatectomy / defer ADT treatment til metastatic
However, clinical details prior to castration resistance and explicit criteria for starting
ADT
were not given. We hypothesize that deferring
ADT
until mets results in outcomes comparable to those reported with early
ADT
, irrespective of NARTD used in nmCRPC."
However, clinical details prior to castration resistance and explicit criteria for starting
ADT
were not given. We hypothesize that deferring
ADT
until mets results in outcomes comparable to those reported with early
ADT
, irrespective of NARTD used in nmCRPC."
George71
in
Advanced Prostate Cancer
Testosterone & PSA
ADT
for 24weeks (2020/05/31)+(2020/08/24)Lupron Depot 22.5mg/12weeks X 2 VNAT-RT 3Gy X 20 fx (2020/06/08 to 2020/07/07) *Testosterone Level under-castration = <0.7nmol/L - <20.189ng/dL *Pre-
ADT
= 10.30nmol/L - 294.19ng/dL (2020/05/04), 15.2nmol/L - 438.04ng/dL (2020/05/27), *Post-
ADT
= <0.2nmol/L -
ADT
for 24weeks (2020/05/31)+(2020/08/24)Lupron Depot 22.5mg/12weeks X 2 VNAT-RT 3Gy X 20 fx (2020/06/08 to 2020/07/07) *Testosterone Level under-castration = <0.7nmol/L - <20.189ng/dL *Pre-
ADT
= 10.30nmol/L - 294.19ng/dL (2020/05/04), 15.2nmol/L - 438.04ng/dL (2020/05/27), *Post-
ADT
= <0.2nmol/L -
doc1947g
in
Prostate Cancer Network
ADT and mental issues
I have done a dozen
ADT
sessions (4 weeks to 5 months). Each time I used a low or high-dose estrogen patch. I did one in January/March and did not use an estrogen patch. So my testosterone was close to zero as well as my estrogen. I have never had mental issues when I did
ADT
. This time I did.
I have done a dozen
ADT
sessions (4 weeks to 5 months). Each time I used a low or high-dose estrogen patch. I did one in January/March and did not use an estrogen patch. So my testosterone was close to zero as well as my estrogen. I have never had mental issues when I did
ADT
. This time I did.
RSH1
in
Advanced Prostate Cancer
ADT collagen/cartilage issues
Wonder if any longtime
ADT
survivors have experienced this nuisance.
Wonder if any longtime
ADT
survivors have experienced this nuisance.
Jbooml
in
Advanced Prostate Cancer
Surgery+radiation+ADT orRadiation + ADT
Have been given 2 treatment options: Surgery+radiation+
ADT
or Radiation +
ADT
. Brachytherapy possibly not an option due to previous TURP. Questions are: What are benefits of surgery?
Have been given 2 treatment options: Surgery+radiation+
ADT
or Radiation +
ADT
. Brachytherapy possibly not an option due to previous TURP. Questions are: What are benefits of surgery?
mysticmini
in
Advanced Prostate Cancer
Start of 36 mo of ADT?
I started on 36 months of
ADT
in Feb 2020 (Neoadjuvant) followed by 44 sessions of IMRT from May 2020 to July 2020 with Continuous
ADT
from Feb to now. When does the 36 months start from? From the first injection in Feb or from the finish of IMRT in July.
I started on 36 months of
ADT
in Feb 2020 (Neoadjuvant) followed by 44 sessions of IMRT from May 2020 to July 2020 with Continuous
ADT
from Feb to now. When does the 36 months start from? From the first injection in Feb or from the finish of IMRT in July.
Dracus
in
Prostate Cancer Network
ADT after castrate resistance
I am trying to get my head round the science of
ADT
after castrate resistance. Why do we continue with
ADT
after it obviously doesn’t have any effect?? Longterm
ADT
has long term side effects – bones especially.
I am trying to get my head round the science of
ADT
after castrate resistance. Why do we continue with
ADT
after it obviously doesn’t have any effect?? Longterm
ADT
has long term side effects – bones especially.
Stoneartist
in
Advanced Prostate Cancer
PSA rising
Because he is 93 he is only treated with
ADT
. His PSA was 100.4 when he started treatment. He had a TURP and found the cancer. My question is can he start having side effects after being on
ADT
for 2 years. His PSA started to rise in 4/20/21.
Because he is 93 he is only treated with
ADT
. His PSA was 100.4 when he started treatment. He had a TURP and found the cancer. My question is can he start having side effects after being on
ADT
for 2 years. His PSA started to rise in 4/20/21.
Ming1828
in
Advanced Prostate Cancer
Neoadjuvant ADT - is a slowing PSA drop rate normal?
The below is his PSA summary: - July 2021: PSA 58 (DX'ed) - Oct 2021: PSA 54 (started neoadjuvant
ADT
) - Jan 2022: PSA 3 (3-months post-
ADT
) - April 2022: PSA 2 (6-months post-
ADT
)
The below is his PSA summary: - July 2021: PSA 58 (DX'ed) - Oct 2021: PSA 54 (started neoadjuvant
ADT
) - Jan 2022: PSA 3 (3-months post-
ADT
) - April 2022: PSA 2 (6-months post-
ADT
)
sixmongoos
in
Advanced Prostate Cancer
Does Erectile function come back after radiation treatment+brachytherapy+2 year ADT?
Did radiation treatment+high-dose brachytherapy+2 year
ADT
. Has anyone among you recovered their erectile function after such a treatment? PSA was <0.1 and testosterone was <20 while on
ADT
. Finished
ADT
in Sept 2021. 6 months later, testosterone (T) is low-normal at 378.
Did radiation treatment+high-dose brachytherapy+2 year
ADT
. Has anyone among you recovered their erectile function after such a treatment? PSA was <0.1 and testosterone was <20 while on
ADT
. Finished
ADT
in Sept 2021. 6 months later, testosterone (T) is low-normal at 378.
A0007720
in
Advanced Prostate Cancer
How long will I need ADT?
I started
ADT
3 months ago which is planned for 12 to 18 months. Start 37 sessions of radiotherapy mid January. My psa last week was 0.01 down from 12 and rising before
ADT
. Wondering if
ADT
is not curative maybe this might be shorter??
I started
ADT
3 months ago which is planned for 12 to 18 months. Start 37 sessions of radiotherapy mid January. My psa last week was 0.01 down from 12 and rising before
ADT
. Wondering if
ADT
is not curative maybe this might be shorter??
Runner1957
in
Prostate Cancer Network
Study Supports Longer ADT Use With Radiation for High-Risk Prostate Cancer
Current National Comprehensive Cancer Network guidelines recommend 18 to 36 months of
ADT
with EBRT and 12 months of
ADT
with EBRT+BT for high-risk disease. In real-world settings, men are receiving considerably shorter durations of
ADT
than indicated.
Current National Comprehensive Cancer Network guidelines recommend 18 to 36 months of
ADT
with EBRT and 12 months of
ADT
with EBRT+BT for high-risk disease. In real-world settings, men are receiving considerably shorter durations of
ADT
than indicated.
Graham49
in
Advanced Prostate Cancer
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