Experiences with Adt | HealthUnlocked

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ADT - What Historical Precedent?

How was it determined that ADT for mPCa, which inevitably results in mCRPca, was preferable to allowing mPCa to progress without ADT? Thanks.How was it determined that ADT for mPCa, which inevitably results in mCRPca, was preferable to allowing mPCa to progress without ADT? Thanks.

6357axbzin Advanced Prostate Cancer

Is ADT killing me?

Is ADT killing me through the side effects? Therefore are the DR's or am I kidding myself. ADT or not?Is ADT killing me through the side effects? Therefore are the DR's or am I kidding myself. ADT or not?

alangeorgein Advanced Prostate Cancer

Can Xtandi actually kill advanced prostate cancer?

After 3 months of no ADT drugs, my testosterone is at 90 and PSA is still at 0.000 ! The only known mets have been to pelvic LNs that were removed at time of RP. Other than RP and ADT, I have had no other treatments. PSA after surgery was still around 11.00 before starting ADT.After 3 months of no ADT drugs, my testosterone is at 90 and PSA is still at 0.000 ! The only known mets have been to pelvic LNs that were removed at time of RP. Other than RP and ADT, I have had no other treatments. PSA after surgery was still around 11.00 before starting ADT.

joeguyin Advanced Prostate Cancer

Radiation with or without ADT?

I'm trying to get better understanding of what results have been for others with and without ADT and the quality of life with ADT.I'm trying to get better understanding of what results have been for others with and without ADT and the quality of life with ADT.

JuliesHusbandin Prostate Cancer Network

More data from the LATITUDE study.

At 6 mo, 40% receiving AAP + ADT and 6.5% receiving PBO + ADT achieved PSA ≤0.1 ng/ml, which was significantly associated with longer rPFS and OS. Median nadir PSA was 0.09 ng/ml with AAP + ADT versus 2.36 ng/ml with PBO + ADT.At 6 mo, 40% receiving AAP + ADT and 6.5% receiving PBO + ADT achieved PSA ≤0.1 ng/ml, which was significantly associated with longer rPFS and OS. Median nadir PSA was 0.09 ng/ml with AAP + ADT versus 2.36 ng/ml with PBO + ADT.

pjoshea13in Advanced Prostate Cancer

ADT Duration After Prostate RT for mPCa (distant metastases)

The established standard for ADT duration after prostate radiation for non-metastatic, localized high risk PCa is 18 months. My RO has me going on intermittent ADT stopping the ADT 6 months after RT. I have distant oligometaststic (bones) high risk (G8) PCa.The established standard for ADT duration after prostate radiation for non-metastatic, localized high risk PCa is 18 months. My RO has me going on intermittent ADT stopping the ADT 6 months after RT. I have distant oligometaststic (bones) high risk (G8) PCa.

6357axbzin Advanced Prostate Cancer

Nubeqa and ARAMIS trial

) compared to placebo plus ADT.) compared to placebo plus ADT.

DarrylAdministratorin Advanced Prostate Cancer

Decipher...0.71 What now?

Started ADT (Casodex/Lupron) October 6th/IMRT January 6th 2020. I was supposed to only do 4 month ADT run, but she wants me to do 6 months. I am tolerating ADT fairly well and will probably do it. She is referring me to a MO.Started ADT (Casodex/Lupron) October 6th/IMRT January 6th 2020. I was supposed to only do 4 month ADT run, but she wants me to do 6 months. I am tolerating ADT fairly well and will probably do it. She is referring me to a MO.

SooHwa99in Advanced Prostate Cancer

Post ADT Side Effects?

ADT didn’t even cause noticeable fatigue.ADT didn’t even cause noticeable fatigue.

6357axbzin Advanced Prostate Cancer

Intermittent ADT

I have been on Lupron ADT for that two years and my PSA has been undetectable all of that time. The ADT side effects of any seriousness have been hot flashes and memory issues. My MO has recommended starting intermittent ADT at the end of my current 3-month Lupron shot.I have been on Lupron ADT for that two years and my PSA has been undetectable all of that time. The ADT side effects of any seriousness have been hot flashes and memory issues. My MO has recommended starting intermittent ADT at the end of my current 3-month Lupron shot.

rocketphdin Prostate Cancer Network

Post ADT Testosterone replacement therapy

I am interested if anyone has undergone testosterone replacement after ADT. Some new studies have suggested low T after ADT can actually accelerate cancer progression..I am interested if anyone has undergone testosterone replacement after ADT. Some new studies have suggested low T after ADT can actually accelerate cancer progression..

tsimin Advanced Prostate Cancer

Non standard Firmagon dosing effective for 3 months from single injection.

My ongoing one-person trial of non-standard dosing for Firmagon (degarelix) for ADT continues: I'm now 3 months out from a single injection of 120Mg. in abdomen fat. (Not the usual starting dose of 240 mg.) as short term adjuvant ADT for RT to pelvic nodes.My ongoing one-person trial of non-standard dosing for Firmagon (degarelix) for ADT continues: I'm now 3 months out from a single injection of 120Mg. in abdomen fat. (Not the usual starting dose of 240 mg.) as short term adjuvant ADT for RT to pelvic nodes.

MateoBeachin Advanced Prostate Cancer

Salvage lymph node dissection in nonmetastatic castration-resistant PCA.

Median time to {second line systemic therapies} was longer in the sLND group than ADT ..)" [u]Conclusion[/u]: "In patients with nonmetastatic, castration-resistant prostate cancer, sLND resulted in greater PSA decrease than ADT.Median time to {second line systemic therapies} was longer in the sLND group than ADT ..)" [u]Conclusion[/u]: "In patients with nonmetastatic, castration-resistant prostate cancer, sLND resulted in greater PSA decrease than ADT.

pjoshea13in Advanced Prostate Cancer

How long does ADT persist

I have been on three separate intervals of ADT. My second interval of four months seemed successfull as my psa was undetectable after several months. I had cryo salvage surgery while on ADT.. What I didn't realize is ADT is effective long after the four months.I have been on three separate intervals of ADT. My second interval of four months seemed successfull as my psa was undetectable after several months. I had cryo salvage surgery while on ADT.. What I didn't realize is ADT is effective long after the four months.

Geoff22in Advanced Prostate Cancer

Indirect Comparisons of Efficacy Between Combination Approaches in Metastatic Hormone-Sensitive Prostate Cancer

All agents, in combination with ADT, were shown to be superior to ADT alone; enzalutamide + ADT had the lowest absolute hazard ratio compared with ADT only.All agents, in combination with ADT, were shown to be superior to ADT alone; enzalutamide + ADT had the lowest absolute hazard ratio compared with ADT only.

Balsam01in Advanced Prostate Cancer

Can ADT Alone Eliminate Individual Bone Mets?

Can ADT Alone Eliminate Individual Bone Mets?Can ADT Alone Eliminate Individual Bone Mets?

6357axbzin Advanced Prostate Cancer

Radiation / ADT

Morris He said Do the Radiation and ADT ! best chance of getting it early ! Met MSK RO. Borys R. Mychalczak Getting Total Body MRI scan 1/31/20. checking for any Mets. if clean ADT (6months). Begin Lupron Shot 22.5 ?(whatever that means). and Casodex 50 mg.Morris He said Do the Radiation and ADT ! best chance of getting it early ! Met MSK RO. Borys R. Mychalczak Getting Total Body MRI scan 1/31/20. checking for any Mets. if clean ADT (6months). Begin Lupron Shot 22.5 ?(whatever that means). and Casodex 50 mg.

sharpcutin Advanced Prostate Cancer

Update on My Lymph Node Metastatic Prostate Cancer

I was on ADT in 2016/17 for 9 months and this time on it for 12 months. Does this mean that I should count 21 months on ADT for the castrate resistant clock? Or the clock started at the start of ADT in October, 2016? I have wondered about the source of my lymph node metastasis.I was on ADT in 2016/17 for 9 months and this time on it for 12 months. Does this mean that I should count 21 months on ADT for the castrate resistant clock? Or the clock started at the start of ADT in October, 2016? I have wondered about the source of my lymph node metastasis.

dac500in Advanced Prostate Cancer

Any ideas why.............?

All, My PSA when on ADT is usually at 0.09. It never deviates more than a hundredth. In December my PSA went up to 0.19 and at that time I received yet another ADT shot. Okay, so maybe I'm now castrate resistant??? Fast forward to yesterday (35 days later), PSA dropped ever so slightly to 0.17.All, My PSA when on ADT is usually at 0.09. It never deviates more than a hundredth. In December my PSA went up to 0.19 and at that time I received yet another ADT shot. Okay, so maybe I'm now castrate resistant??? Fast forward to yesterday (35 days later), PSA dropped ever so slightly to 0.17.

alephnullin Advanced Prostate Cancer

Late-onset ED from radiation

I realize that there is nothing I can now do (or is there, other than keeping things going post-ADT?) to alter what will be. I would appreciate input from men who had RT, but didn't receive ADT, or had only a few months, and wound up developing ED.I realize that there is nothing I can now do (or is there, other than keeping things going post-ADT?) to alter what will be. I would appreciate input from men who had RT, but didn't receive ADT, or had only a few months, and wound up developing ED.

Handdrummer777in Prostate Cancer And Gay Men