Experiences with

Androgen deprivation therapy (ADT)

Poster Besides having EBRT and brachotherapy, I am on ADT (Firmagon and Bicalutamid). Given the above apparently negative impact of ADT, does anyone have any idea whether I should consider replacing or complementing my ADT with systemic therapy?

MD Anderson recommends docetaxel and ADT with primary site radiation after. I see there's some data of maintaining better control with early chemo, but wanted to know if anyone else has experienced it. My urologist recommended ADT and IMRT to all sites.

Salvage RT to prostate bed and combined ADT (casodex and GnRH) started at this level (0.16). RT was from August-October and ADT just finished a week ago. Three months in (around October) his PSA was 0.01. Now, a week off ADT and three months out from SRT, his PSA is 0.16 again. What does this mean?

Reresearch indicates that the use of estridol patches while on adt may mitigate some of the side effects of adt. My question is on the dosage of estradiol patches. Does anyone have information or experience with the proper dosage of estradiol patches to reduce adt side effects ?

"Overall, 74 (22.6%), 63 (19.2%), and 191 (58.2%) patients were treated with ADT, EBRT, and sLND for lymph node-only recurrence. ... "Both sLND (HR 0.56 ...) and EBRT (HR 0.46 ...) were associated with better {radiological recurrence} than ADT.

Thinking of ADT worsening his cardiac disease.. Best wishes to all in these uncertain times!

Does anyone know the cost of this drug?Insurance has denied it. I have seen on the internet a price of 2300 monthly. My doctors want me to do short term ht . The safety aspects seem safer than lupron with quicker recovery time once off the drug.

What have people found effective to control development of breast tissue while on ADT? I am 3 months in on ADT and have always had larger pecs....but noticing they are getting bigger. I know this needs to be proactive....so what are possible approaches to controlling this? Thanks

Have any of you experienced testicular pain while on ADT treatment? My husband has some tenderness.

I've been on ADT for 14 3/4 months. (1st month was Degarelix, then 12 months Lupron, now back to Degarelix). I want to try to reach 24 months of ADT. I know of the Nabid study thanks to Tall (Heroic, Generous, Knowledgeable) Allen, but want to attain 2 years minimum of ADT.

I will probably start ADT in 3 weeks. Will this interfere with the PSMA scan? If the ADT works will it stop PC sites from showing or will they still show on the scan? It is not likely that I can get the scan before ADT unless I postpone the ADT.

He said PSA of 1.0 would be the trigger to resume ADT, I'm currently undetectable. Has anyone else had a huge PSA increase after skipping one or maybe two shots? Thanks

In the trial, the subject men were randomized to receive continued ADT plus Zytiga and prednisone or Zytiga plus prednisone alone(without ADT) to determine the value of continuing ADT.

Leaning toward ADT vs ADT/SRT. Also, anyone have any experience with Dr. Kresl, Cyberknife Phoenix Az. Still considering SRT IMRT with him or Dr. Wong at Mayo. Thanks for any thoughts! I need to decide ADT or SRT soon. I really would like to bring in PSMA Pet into decision. Thanks as always.

I read yesterday that a new phase RTOG 9601 validates DECIPHER as a predictor of OS, and also showed ADT to be beneficial in DECIPHER high risk men receiving ART, especially those with low PSA.

Been on Lupron and Zytiga/Prednisone for 2 years, a recent visit at Dana Farber, my doc said - to go on ADT vacation!

I am T2N1, Gl9, Post-op RP (10/2019), Recurrence, and now on ADT (Firmagon) awaiting Salvage RT.

I was not a victim of breast enlargement during my first injection of Lupron or while on Casodex but I do not know if it is any indication that my breasts won't grow once I start ADT again in a few weeks. Did any of you experience growing breasts while under ADT?

This is 8 months after my last ADT Implant, and 5 months after the drug has been depleted by my body. This really surprised me, I expected my Testosterone to be at least on the road to recovery, suppose it explains why I feel so crap :-( Is this normal after ADT, I was only on ADT for 7 months?

During ADT break my PSA increased rapidly from 0.07 to 0.453 while T increased to 147 over a period of 9 months.