Experiences with

Androgen deprivation therapy (ADT)

Started ADT and abiraterone then 4m later pelvic RT. PSA still undetectable and Testosterone <2. The original plan was for 2 years of ADT and AA. At ESMO 2021 Dr. Attard suggested that SOC should be 3 years of ADT for patients falling into this and similar locally advanced subsets.

Thus, it follows many RT patients have only ADT as salvage, and ADT not considered curative as is a successful salvage treatment. So, since yes salvage RT readily available for surgery patients, do RP patients overall during their lifetimes endure less time on ADT than do those men who choose ADT?

Anybody quit adt against medical advice because of quality of life issues? Thanks

Can this be caused by my ADT treatments? Is it reversible? I never had this before I started ADT. Thanks

Do I have an Orchiectomy or use ADT medications. from what I have read, Orchiectomy has shown to have better result than ADT in terms of long term survival plus it is a lot cheaper than paying indefinitely for ADT drugs and may have less health issues.

I will most likely start ADT or ADT+. Recommendation are welcomed.

"Who should not get ADT? Anybody else with prostate cancer. If you just have a rising PSA after radiation therapy or radical prostatectomy, that is not a good enough reason for a doctor to put you on ADT.

I am one month away from completing a 24 month ADT treatment plan. During that time, my wife tells me that my hair has considerably thicken over my previously bald spot. It's still pretty thin, but not nearly as much as it was before I started ADT.

However, clinical details prior to castration resistance and explicit criteria for starting ADT were not given. We hypothesize that deferring ADT until mets results in outcomes comparable to those reported with early ADT, irrespective of NARTD used in nmCRPC."

ADT for 24weeks (2020/05/31)+(2020/08/24)Lupron Depot 22.5mg/12weeks X 2 VNAT-RT 3Gy X 20 fx (2020/06/08 to 2020/07/07) *Testosterone Level under-castration = <0.7nmol/L - <20.189ng/dL *Pre-ADT = 10.30nmol/L - 294.19ng/dL (2020/05/04), 15.2nmol/L - 438.04ng/dL (2020/05/27), *Post-ADT = <0.2nmol/L -

I have done a dozen ADT sessions (4 weeks to 5 months). Each time I used a low or high-dose estrogen patch. I did one in January/March and did not use an estrogen patch. So my testosterone was close to zero as well as my estrogen. I have never had mental issues when I did ADT. This time I did.

Wonder if any longtime ADT survivors have experienced this nuisance.

Have been given 2 treatment options: Surgery+radiation+ADT or Radiation + ADT. Brachytherapy possibly not an option due to previous TURP. Questions are: What are benefits of surgery?

I started on 36 months of ADT in Feb 2020 (Neoadjuvant) followed by 44 sessions of IMRT from May 2020 to July 2020 with Continuous ADT from Feb to now. When does the 36 months start from? From the first injection in Feb or from the finish of IMRT in July.

I am trying to get my head round the science of ADT after castrate resistance. Why do we continue with ADT after it obviously doesn’t have any effect?? Longterm ADT has long term side effects – bones especially.

Because he is 93 he is only treated with ADT. His PSA was 100.4 when he started treatment. He had a TURP and found the cancer. My question is can he start having side effects after being on ADT for 2 years. His PSA started to rise in 4/20/21.

The below is his PSA summary: - July 2021: PSA 58 (DX'ed) - Oct 2021: PSA 54 (started neoadjuvant ADT) - Jan 2022: PSA 3 (3-months post-ADT) - April 2022: PSA 2 (6-months post-ADT)

Did radiation treatment+high-dose brachytherapy+2 year ADT. Has anyone among you recovered their erectile function after such a treatment? PSA was <0.1 and testosterone was <20 while on ADT. Finished ADT in Sept 2021. 6 months later, testosterone (T) is low-normal at 378.

I started ADT 3 months ago which is planned for 12 to 18 months. Start 37 sessions of radiotherapy mid January. My psa last week was 0.01 down from 12 and rising before ADT. Wondering if ADT is not curative maybe this might be shorter??

Current National Comprehensive Cancer Network guidelines recommend 18 to 36 months of ADT with EBRT and 12 months of ADT with EBRT+BT for high-risk disease. In real-world settings, men are receiving considerably shorter durations of ADT than indicated.