So I am following the de-escalation trials as discussed here:
dailynews.ascopubs.org/do/c....
I am working with my own MO on de-escalation so no ADT injection for me at the end of September and so am on the Apalutamide monotherapy. ( only been a couple of weeks).
Will report my QOL situation plus any change to. My PSA which has been undetectable for 14 months.
Anyone on these trials as I would be interested to hear.
Regards all
Lol! Im confused is it de escation, se escalation, or deescalarion?
You should take it easy on the liquid meds brother.😜
I was looking for a bit more info on Arm A of Libertas trial as it seems a bit vague
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De-escalation is a polite way of saying: "stop the silliness of throwing around kitchen sinks". Intermittent anti-androgen treatment, like the Libertas trial, is better than fixed standard dosage, but lacking behind proportional dosage adjustment. OP is aware of my Bicalutamide maneuvers, but persuading his MO isn't a trivial thing.
I am in my own n=1 de-escalation plan doing IADT and then vacationing...
Based on the article, I am an excellent candidate based on my PSA scores...
Bonne chance, mon ami
Fish
