I have been struggling with anxiety and depression for years. It has gotten worse over the last five years. I've tried a number of antidepressant and counseling. Antidepressants I've tried (Paxil, Lexapro, and others I can't remember the name of) don't work and make me feel sick. I don't sleep well and wake up in the middle of the night gripped by anxiety. I have to take a Xanax to get back to sleep. Sleep meds work reverse. My family situation is not good. My adult son has schizoaffective disorder and I am his guardian. l He also has stage 5 kidney disease and is facing dialysis soon. I deal with him daily, and it's not easy. My daughter who lives in the West doesn't stay with any job for any length of time. Her son (my grandson) has mental health problems and recently tested positive for cocaine when he tried to join the army. My husband is great, but I often am irritable with him and it causes problems because I'm so miserable. I don't know how to accept my situation and be happy.