March 2008: DiagnosedAge 55 via Annual Physical Exam; PSA: 8.5; DRE neg.
Prostate biopsy: Prostate cancer in 16/18 samples. Gleason Estimate 8-10; DaVinci Robotically-assisted laparoscopic radical prostatectomy (RALRP) w/ lymph node dissection;
Dx: Stage III prostate cancer; T3b - Tumor (70% of prostate) with positive margins into seminal vesicles. GS 10 (5 + 5). Lymph node: negative N0.
July 2008 - Feb 2009: PSA undetectable
Feb 2009: Age: 56. Tomotherapy Image-Guided Radiation Therapy (IGRT); 200 rads x 37 treatments, 7400 rads.
July 2009 - Nov 2012PSA Undetectable
Nov 2012-Nov 2014 PSA slow rise from 0.09 to 3.91 while trying MPX clinical trial
Dec 2014Fine needle biopsy of bladder tissue swelling positive for prostate cancer; radiation already maximum rads to abdomen area. Stage IV: T4, N0.
Rx: Continuous androgen deprivation therapy (ADT) Casodex and Eligard.
Jan 2015at age 62 PSA 5.44 began Clinical Trial S1216 Phase III Randomized Trial Arm 1: Lupron + TAK-700, Arm 2: Eligard + Casodex. Selected for Arm 2.
Initiated Eligard 22.5mg 3-month shot and Casodex (Bicalutamide) daily pill continuous combined ADT.
Feb 2015: PSA: 0.572
Mar 2015: PSA: < 0.064
Sept 2015:Began lower dose Effexor-XR 37.5 mg and reduced
Jan 2016Age 63: CT w/ contrast chest, abdomen & pelvis; resolution of thickening in bladder wall!