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Prostate disease

Prostate problems are common, particularly in men aged over 50.

The prostate is a small gland found only in men. It surrounds the tube that carries urine out of the body (urethra).

The prostate gland produces a thick, white fluid that gets mixed with sperm to create semen.

The prostate gland is about the size and shape of a walnut but tends to get bigger as you get older. It can sometimes become swollen or enlarged by conditions such as:

  • prostate enlargement
  • prostatitis (inflammation of the prostate)
  • prostate cancer

Prostate enlargement

Prostate enlargement is a very common condition associated with ageing. More than 1 in 3 of all men over 50 will have some symptoms of prostate enlargement.

It's not known why the prostate gets bigger as you get older, but it is not caused by cancer and does not increase your risk of developing prostate cancer.

An enlarged prostate can put pressure on the urethra, which can affect how you urinate.

Signs of an enlarged prostate can include:

  • difficulty starting or stopping urinating
  • a weak flow of urine
  • straining when peeing
  • feeling like you're not able to fully empty your bladder
  • prolonged dribbling after you've finished peeing
  • needing to pee more frequently or more suddenly
  • waking up frequently during the night to pee 

See your GP if you notice any problems with, or changes to, your usual pattern of urination.

Simple measures such as reducing the amount you drink (especially tea, coffee and alcohol) before bed can sometimes help control the symptoms. Medication can help reduce the size of your prostate and relax the muscles of your bladder.

In severe cases that do not get better with medication, the inner part of the prostate can be surgically removed.

Prostatitis

Prostatitis is where the prostate gland becomes inflamed (swollen). It's sometimes caused by a bacterial infection, although more often no infection can be found and it's not clear why it happened.

Unlike prostate enlargement or prostate cancer – which usually affect older men – prostatitis can develop in men of all ages. However, it's generally more common in men aged between 30 and 50.

Symptoms of prostatitis can include:

  • pain in the pelvis, genitals, lower back and buttocks
  • pain when urinating
  • a frequent need to pee
  • difficulty urinating, such as problems starting to pee
  • pain when ejaculating
  • pain in the perineum (the area between the anus and scrotum), which is often made worse by prolonged sitting

See your GP if you have these symptoms.

Prostatitis can be treated using a combination of painkillers and a type of medication called an alpha-blocker, which can help to relax the muscles of the prostate and bladder neck. Medication that shrinks the prostate gland may also be helpful.

Most men will recover within a few weeks or months, although some will continue to have symptoms for longer.

Prostate cancer

In the UK, prostate cancer is the most common type of cancer in men, with more than 40,000 new cases diagnosed every year.

It's not clear why it occurs, but your chances of developing prostate cancer increase as you get older. The condition mainly affects men over 65, although men over 50 are also at risk.

The risk of developing prostate cancer is also increased depending on your:

  • ethnic group – prostate cancer is more common among men of African-Caribbean and African descent than in Asian men
    • family history – having a brother or father who developed prostate cancer under the age of 60 seems to increase your risk of developing it, and having a close female relative who developed breast cancer may also increase your risk of prostate cancer

The symptoms of prostate cancer can be difficult to distinguish from those of prostate enlargement. They may include:

  • needing to pee more frequently, often during the night
  • needing to rush to the toilet
  • difficulty in starting to pee (hesitancy)
  • straining or taking a long time while peeing
  • weak flow
  • feeling that your bladder has not fully emptied
  • blood in urine or blood in semen

You should see your GP if you have these symptoms. It's much more likely to be prostate enlargement, but it's important to rule out cancer.

The outlook for prostate cancer is generally good because, unlike many other types of cancer, it usually progresses very slowly. Many men die with prostate cancer rather than as a result of having it.

Prostate cancer therefore does not always need to be treated immediately. Sometimes, it may initially just be monitored and only treated if it gets worse.

HealthUnlocked contains information from NHS Digital, licensed under the current version of the Open Government Licence

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41,361 public posts

From PSA 1000+, and screaming with pain while urinating to Undetectable!

Unbelievable, diagnosed with PSA 1000+, metastatic prostate cancer disease, 2 years ago with horrible pain when urinating blood, pelvic scan showed cancer everywhere - to undetectable today, current PSA < 0.02.
Unbelievable, diagnosed with PSA 1000+, metastatic prostate cancer disease, 2 years ago with horrible pain when urinating blood, pelvic scan showed cancer everywhere - to undetectable today, current PSA < 0.02.
DarkEnergy
in Advanced Prostate Cancer

Could prostate drugs reduce Parkinson's disease risk?

https://www.medicalnewstoday.com/amp/articles/could-prostate-drugs-reduce-parkinsons-disease-risk A new study suggests that repurposing glycolysis-enhancing drugs such as terazosin, which is typically used to treat an enlarged prostate, may reduce the risk of Parkinson’s disease in men.
https://www.medicalnewstoday.com/amp/articles/could-prostate-drugs-reduce-parkinsons-disease-risk A new study suggests that repurposing glycolysis-enhancing drugs such as terazosin, which is typically used to treat an enlarged prostate, may reduce the risk of Parkinson’s disease in men.
JayPwP
in Cure Parkinson's

Just sharing another promising trial for anyone interested. I know it’s a phase 1 however still wanted to post

https://www.biospace.com/article/releases/immunitybio-announces-12-month-overall-survival-probability-of-83-percent-in-nci-led-phase-1-study-of-multi-targeted-had5-immunotherapy-vaccine-in-patients-with-advanced-metastatic-prostate-cancer/
https://www.biospace.com/article/releases/immunitybio-announces-12-month-overall-survival-probability-of-83-percent-in-nci-led-phase-1-study-of-multi-targeted-had5-immunotherapy-vaccine-in-patients-with-advanced-metastatic-prostate-cancer/
Faith1111
in Advanced Prostate Cancer
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Treatment-Emergent Neuroendocrine Prostate Cancer: Frontiers in Oncology

https://www.frontiersin.org/articles/10.3389/fonc.2020.571308/full citation: Frontiers in Oncology Treatment-Emergent Neuroendocrine Prostate Cancer: A Clinicopathological and Immunohistochemical Analysis of 94 Cases Front Oncol 2020 Feb 01;[EPub Ahead of Print], Q Zhang, Y Han, Y Zhang, D Liu, J
https://www.frontiersin.org/articles/10.3389/fonc.2020.571308/full citation: Frontiers in Oncology Treatment-Emergent Neuroendocrine Prostate Cancer: A Clinicopathological and Immunohistochemical Analysis of 94 Cases Front Oncol 2020 Feb 01;[EPub Ahead of Print], Q Zhang, Y Han, Y Zhang, D Liu, J
Balsam01
in Advanced Prostate Cancer

Association between periodontal disease and prostate cancer

Recently, increasing studies have explored the correlation of periodontal disease with the risk of prostate cancer. However, the findings were inconsistent. Hence, this study aims to investigate the association between periodontal disease and the risk of prostate cancer by a meta-analysis.
Recently, increasing studies have explored the correlation of periodontal disease with the risk of prostate cancer. However, the findings were inconsistent. Hence, this study aims to investigate the association between periodontal disease and the risk of prostate cancer by a meta-analysis.
Graham49
in Advanced Prostate Cancer

latest from Prostate Foundation

I have been reading this site for 2+ months. Am on the mail list from Prostate Cancer Foundation. Here is their latest Scientific Retreat information with downloads of latest research and trials. https://www.pcf.org/scientific-retreat/reports/
I have been reading this site for 2+ months. Am on the mail list from Prostate Cancer Foundation. Here is their latest Scientific Retreat information with downloads of latest research and trials. https://www.pcf.org/scientific-retreat/reports/
btca
in Fight Prostate Cancer

Writing for a friend. He was diagnosed with moderately differentiated adenocarcinoma in the prostecic bed that is close to the rectal tumor

A friend of 45 years called me to say after having had his rectum removed 2 1/2 years ago there is a recurrence of cancer. I thought when we spoke he had rectal cancer. I was surprised when he said 'moderately differentiated adenocarcinoma in the prostecic ?? bed that is close to the rectal tumor
A friend of 45 years called me to say after having had his rectum removed 2 1/2 years ago there is a recurrence of cancer. I thought when we spoke he had rectal cancer. I was surprised when he said 'moderately differentiated adenocarcinoma in the prostecic ?? bed that is close to the rectal tumor
Bluebird11
in Advanced Prostate Cancer

Katherine Virgo, PhD, on Updated ASCO Prostate Cancer Guidelines - MedPage Today Interview - 02/17/2021

A good summary of the recent update (after 13 YEARS?) to the ASCO Guidelines for treatment of men with noncastrate advanced, recurrent, and metastatic disease. When looking at the range of trials and the current lack of consensus on best SOC, it seems our generation of patients are still basically guinea
A good summary of the recent update (after 13 YEARS?) to the ASCO Guidelines for treatment of men with noncastrate advanced, recurrent, and metastatic disease. When looking at the range of trials and the current lack of consensus on best SOC, it seems our generation of patients are still basically guinea
cujoe
in Fight Prostate Cancer

70th Birthday

My father has turned 70 today! He's been battling stage 4 prostate cancer with very advanced bone mets for the past 4 years. At his age with his condition he is so thankful to be alive. Reading these forums sometimes I do get confused what is considered advanced prostate cancer or perhaps people priorities
My father has turned 70 today! He's been battling stage 4 prostate cancer with very advanced bone mets for the past 4 years. At his age with his condition he is so thankful to be alive. Reading these forums sometimes I do get confused what is considered advanced prostate cancer or perhaps people priorities
Howmuchisthefish
in Advanced Prostate Cancer

Terazosin ? I have researched using Parkinson's Online - 19 items so far . . .

by Clare Bale, Parkinson’s UK 2102 Feb Could prostate drugs reduce Parkinson’s disease risk?
by Clare Bale, Parkinson’s UK 2102 Feb Could prostate drugs reduce Parkinson’s disease risk?
FMundo
in Cure Parkinson's

21 Short Films About Bone Health

https://bit.ly/3itStqV 21 Short Films About Bone Health presents easy to understand information about prostate cancer and the effects of treatments on bone health, bone density, osteoporosis and fractures. Many men die from bone related injuries long before their prostate cancer might have killed them
https://bit.ly/3itStqV 21 Short Films About Bone Health presents easy to understand information about prostate cancer and the effects of treatments on bone health, bone density, osteoporosis and fractures. Many men die from bone related injuries long before their prostate cancer might have killed them
DarrylAdministrator
in Advanced Prostate Cancer

Stopped Receiving Posts!

FYI, in case this happened to you, I stopped receiving Advanced Prostate Cancer Posts. Darryl suggested I write an email to support@healthunlocked.com which I did. Waiting for reply.
FYI, in case this happened to you, I stopped receiving Advanced Prostate Cancer Posts. Darryl suggested I write an email to support@healthunlocked.com which I did. Waiting for reply.
6357axbz
in Advanced Prostate Cancer

Darth Vader is gone

David Prowse who played Vader passed. He was 85 but was being treated for prostate cancer. May the force be with Vader.
David Prowse who played Vader passed. He was 85 but was being treated for prostate cancer. May the force be with Vader.
Howard53545
in Advanced Prostate Cancer

Loss and revival of androgen receptor signaling in advanced prostate cancer

That said, the stronger inhibition of the AR signaling axis has led in recent years to an increase of prostate cancers that de-differentiate into AR-negative disease. [u]Unfortunately, this process is intimately linked with a poor prognosis.
That said, the stronger inhibition of the AR signaling axis has led in recent years to an increase of prostate cancers that de-differentiate into AR-negative disease. [u]Unfortunately, this process is intimately linked with a poor prognosis.
pjoshea13
in Advanced Prostate Cancer

Prostate radiation

What are the possible side effects for radiation to my prostate in six doses
What are the possible side effects for radiation to my prostate in six doses
Squirrel71
in Advanced Prostate Cancer

Enzalutamide resistance & IKKB

"Although enzalutamide (ENZ) has been widely used to treat de novo or castration-resistant metastatic prostate cancer, resistance develops, and disease progression is ultimately inevitable.
"Although enzalutamide (ENZ) has been widely used to treat de novo or castration-resistant metastatic prostate cancer, resistance develops, and disease progression is ultimately inevitable.
pjoshea13
in Advanced Prostate Cancer

Vitamin D levels and the risk of ... PCa mortality

New Danish study below [1]. "All men who underwent prostatic biopsy in the Danish PCa Registry (DaPCaR) and who had a serum vitamin D measurement during the period 2004 to 2010 (n = 4,065) were identified. Men were categorized by clinical cut-offs based on seasonally adjusted serum vitamin D levels
New Danish study below [1]. "All men who underwent prostatic biopsy in the Danish PCa Registry (DaPCaR) and who had a serum vitamin D measurement during the period 2004 to 2010 (n = 4,065) were identified. Men were categorized by clinical cut-offs based on seasonally adjusted serum vitamin D levels
pjoshea13
in Advanced Prostate Cancer

Prostate stage 4

My dad has Stage 4 prostate cancer which spread to his kidneys. He has a stent in, and he recently had swelling in his foot and penis. The Er said he had a uti. Today he now has swelling of foot and scrotum? Please someone tell me what this is? He’s going to the dr. Tomorrow to get a catheter or replace
My dad has Stage 4 prostate cancer which spread to his kidneys. He has a stent in, and he recently had swelling in his foot and penis. The Er said he had a uti. Today he now has swelling of foot and scrotum? Please someone tell me what this is? He’s going to the dr. Tomorrow to get a catheter or replace
Lisabrody
in Advanced Prostate Cancer

Treatment Considerations for Prostate Cancer Progressing After Combination Therapy for mCSPC

utm_source=newsletter_8140&utm_medium=email&utm_campaign=treatment-considerations-for-prostate-cancer-from-localized-disease-through-castration-sensitive-metastatic-disease-asco-2020-educational-symposium-plenary-session-highlights
utm_source=newsletter_8140&utm_medium=email&utm_campaign=treatment-considerations-for-prostate-cancer-from-localized-disease-through-castration-sensitive-metastatic-disease-asco-2020-educational-symposium-plenary-session-highlights
tango65
in Advanced Prostate Cancer

Whole Brain Radiation for Multiple Prostatic Metastases

I was diagnosed with metastatic prostate cancer in 2006. My treatments have included 2 rounds of chemotherapy, 3 rounds of radiotherapy to the pelvic area and many drugs too numerous too mention. I have just completed whole brain radiation due to the discovery of multiple metastatic lesions. I am currently
I was diagnosed with metastatic prostate cancer in 2006. My treatments have included 2 rounds of chemotherapy, 3 rounds of radiotherapy to the pelvic area and many drugs too numerous too mention. I have just completed whole brain radiation due to the discovery of multiple metastatic lesions. I am currently
APC1234
in Advanced Prostate Cancer
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