Experiences with

Prostate disease

It's not a cure, but it seems to be able to predict the evolution of the disease, allowing for a more targeted approach... https://www.medicaldevice-network.com/news/new-liquid-biopsy-technique-detects-prostate-cancer-disease-evolution/

The goal is to improve outcomes for mCRPC patients with limited treatment options https://prostatewarriors.com/2025/04/11/phase-2-trial-enrolling-combination-therapy-for-metastatic-castration-resistant-prostate-cancer/

I was just reading today about the recent UCLA study (published 12/13/24) that found that omega-3‘s and fish oil slow the proliferation of prostate cancer. The study only applied to men on active surveillance. Does anyone have any information about its benefit for men with advanced PCa?

https://prostatewarriors.com/2025/03/28/new-radiotherapy-atnm-400-targets-advanced-prostate-cancer/

ARANOTE Trial Explores Darolutamide’s Role in High and Low-Volume Metastatic Prostate Cancer - Fred Saad https://www.urotoday.com/aranote-te/videos/mediaitem/4592-aranote-trial-explores-darolutamide-s-role-in-high-and-low-volume-metastatic-prostate-cancer-fred-saad.html?

This article mentions activation of TREG cells and an investigational medication https://www.thebrighterside.news/post/prostate-cancer-antibody-drug-shows-success-in-dogs/ "...mogamulizumab — an antibody drug cloned from other white blood cells that blocks the CCR4 receptor"

grandfather has been given Xofigo, which is a radioactive compound that mimics calcium to deliver radiation in the bones to cancer cells. This is quite a heavy treatment and i want to optimally support in bringing his PSA value's down. Quite strong stuff. What are some remedies methods I can provide

https://www.cancer.gov/news-events/cancer-currents-blog/2025/metastatic-prostate-cancer-combination-treatments?cid=eb_govdel

Given the potential health benefits of saffron extracts, more studies are needed to fully elucidate the antitumor properties of saffron in prostate carcinogenesis. Chamomile and PCa J Cancer. 2023 Feb 5;14(3):490–504.

Age: 68 “3T MRI OF THE PROSTATE WITH AND WITHOUT CONTRAST and with 3D post-processing CLINICAL HISTORY: Prostate Cancer PSA 9.4 ng/mL (9/27/2024) COMPARISON: None. TECHNIQUE: MRI of the pelvis was performed on a 3 Tesla MAGNETOM Vida scanner. A transabdominal phased array was used.

Incredible and exciting updates on use of CRSPR/Cas9 technology to fight multiple aspects of Prostate Cancer and metastasis. https://biosignaling.biomedcentral.com/articles/10.1186/s12964-024-01833-1

ATR inhibitors can anyway help PARPi in case of mono allelic ATM mutation https://prostatewarriors.com/2025/01/18/parp-inhibitors-in-prostate-cancer-navigating-the-complexities-of-dna-repair/

By targeting PNKP, researchers aim to make prostate cancer cells more vulnerable to therapy-induced DNA damage. This approach is especially promising for tumors with mutations in DNA repair genes like ATM and BRCA, which are often found in advanced prostate cancer.

You can search on YouTube for Eugene Kwon DIY Prostate Cancer Treatment. I think he answers many common questions Advanced PCa patients have that come to this forum.

While FAP is prevalent in 50%-80% of prostate cancers, no prostate cancer patients were reported in the trial as of April 2024. But the trial is still recruiting at the moment!

https://openmedscience.com/actinium-225-rosopatamab-a-breakthrough-in-metastatic-prostate-cancer-treatment/

My question is how many friends (not just acquaintances) have you lost to this disease in the last decade or so ?

Additionally, the PROLONG study found that MDT, when used alongside systemic therapies for de novo low-volume hormone-sensitive prostate cancer, improved survival. Even in polymetastatic disease, MDT has proven to be a safe and feasible option.

This finding would be consistent with metastatic prostate cancer. There is no PSMA avidity of the small lytic lesion involving the anterior right 10th rib and the lesion involving the spinous process of T5 for which a metastatic disease from prostate cancer cannot be confirmed.

Local radiotherapy (RT) in hormone-sensitive metastatic prostate cancer (mHSPC) can benefit patients with high-burden disease, not just those with low metastatic loads.