Results are in from Blue Horizon, bit confused. - Thyroid UK

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Results are in from Blue Horizon, bit confused.

Polo22 profile image
12 Replies

Don't know if I have mucked it up but here goes

TSH 8.9 0.27 - 4.20

T4 total 106.0 66 - 181

Free T4 17.2 12.0 - 22.0

Free T3 3.11 3.1 - 6.8

Anti-Thyroidperoxidase abs <9.0 <34

Anti-Thyroglobulin Abs 11 <115

have been self injecting B12 for a few months, and supplementing magnesium, vit D, C, E, A, B6, Zinc, Selenium.

vit D has gone up from from 10 to 53, Magnesium from 0.82 to

0.90. Ferritin up from 107 to 112,

B12 was 354 no reference , now 1476 145 - 569

CRP gone from 6 no reference, to 6.85 >5.0,

any help or advice greatly appreciated.

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Polo22
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SeasideSusie profile image
SeasideSusieRemembering

Polo22

What do you mean by "no reference" against some of those results? You have included the reference ranges with them.

Did you do the test as we advise, ie no later than 9am, water only before the test, last dose of Levo 24 hours before test? If you've had a dose change did you leave 8 weeks before testing?

TSH 8.9 0.27 - 4.20

T4 total 106.0 66 - 181

Free T4 17.2 12.0 - 22.0

Free T3 3.11 3.1 - 6.8

Yes, this is confusing. The TSH is telling us you are undermedicated, as is the FT3, yet the FT4 is 52% through range which isn't too bad and makes me think you may have taken your Levo before the test?

Anti-Thyroidperoxidase abs <9.0 <34

Anti-Thyroglobulin Abs 11 <115

These low levels don't suggest Hashi's but it is possible to have Hashi's without raised antibodies.

B12 was 354 no reference , now 1476 145 - 569

have been self injecting B12 for a few months

Did you start self injecting after the result of 354?

Blue Horizon use the unit of measurement of pmol/L.

354pmol/L equates to 479.67pg/ml.

That result doesn't suggest B12 deficiency. It's slightly lower than the level where it may be possible to experience deficiencies begin to appear in the cerebrospinal fluid which can happen when level is below 550pg/ml" according to the book "Could it be B12?" by Sally M. Pacholok. It also says "For brain and nervous system health and prevention of disease in older adults, serum B12 levels should be maintained near or above 1000 pg/ml."

So unless you were tested for B12 deficiency then B12 injections weren't necessarily the way to go. A good quality B Complex should have improved your level without the need for a separate B12 supplement or injection.

Are you still injecting?

Do you also take a B Complex, this is needed when taking B12 in any form as it helps balance all the B vitamins.

, and supplementing magnesium, vit D, C, E, A, B6, Zinc, Selenium.

Do you need the Vit A, it's a fat soluble vitamin and excess gets stored and leads to toxicity.

Did you test zinc and copper? We hypos tend to have one high and the other low so we really need to know what, if anything, we need to supplement rather than just take one without testing first.

vit D has gone up from from 10 to 53,

How much are you taking? Are you also taking Vit K2-MK7 which is an important cofactor when supplementing with D3.

You still have a way to go to reach the level recommended by the Vit D Society and Grassroots Health, which is 100-150nmol/L.

Magnesium from 0.82 to 0.90.

Testing magnesium is unreliable. About 99% of magnesium is stored in bone, muscles and soft tissues, leaving about 1% in the blood. So testing what's in the blood isn't giving an accurate picture of our magnesium status.

A red cell magnesium test is the better indicator of magnesium status, not the standard serum magnesium test. The red cell test is expensive and not included in these test bundles.

CRP gone from 6 no reference, to 6.85 >5.0,

This is an inflammation marker so is showing some inflammation somewhere.

Ferritin up from 107 to 112,

Ferritin can be raised when inflammation is present so this may be higher than your normal level due to inflammation which the CRP is suggesting.

Polo22 profile image
Polo22 in reply toSeasideSusie

Hi thanks for responding so quickly , I'll try and go through and answer your queries in order as my head is a bit battered, having major wobble. So where I have put no reference, I meant there was no reference listed with initial results from GP, at least not on the My GP app, the references ranges included are listed with Bluehorizon results. Yes did leave 24 hours + since last dose before test, did not eat before, had some water, test done before 9.am around 08.30, just after maybe. No dose change.

B12 just realised didn't include units 354 ng/L was original result, lots of neuro symptoms, numbness / tingling, brain fog, anxiety, memory problems, pain, hence started SI B12. It is the different un its of measurement used that is confusing me. not taking a B complex, some B's included in other stuff I am taking, trying to get organised, there is small amount B6 and B 9 in other stuff. Vit A is small amount listed in the Zinc supplement with the B's in haven't tested yet for Copper or Zinc, Originally got oral tabs from GP, but then they recommended OTC tabs, they are quite low dosage and suspecting may have an absorption problem went for Oral spray , have recently got the one with K2( BetterYou D 3000+K2 ) Magnesium, I know not a lot is in serum but didn't know about red cell test, having a rather embarrassing cash flow situation at the moment, piss poor, so trying to be careful. CRP could be had knee pop , months ago now but have been less active, crippled literally and had steroid injections in knee it is taking forever to heal but now hobbling with less pain. Thanks again for response appreciated.

SeasideSusie profile image
SeasideSusieRemembering in reply toPolo22

B12 just realised didn't include units 354 ng/L was original result, lots of neuro symptoms, numbness / tingling, brain fog, anxiety, memory problems, pain, hence started SI B12.

Ah, OK, that makes a difference then. I thought that was a Blue Horizon result and I know they use pmol/L.

It is the different un its of measurement used that is confusing me.

It is confusing when there are different units. If you want to know how to convert them then

pg/ml is the same as ng/L - no conversion required

to convert pmol/L to pg/ml multiply by 1.355

to convert pg/ml or ng/L to pmol/L then divide the pg or ng result by 1.355

Polo22 profile image
Polo22 in reply toSeasideSusie

Thanks,, that conversion formulae made my head hurt , not confident with Maths, had a teacher , like 40 something years ago kept telling me I was thick because he couldn't explain various formula to me and me understand , not my fault he was thick, 😊 always believed him, passed my GCSE Maths in 2017 , without studying,

SeasideSusie profile image
SeasideSusieRemembering in reply toPolo22

OK, does this make it easier.

Let's use your result of 354ng/L (which is the same as pg/L) and say we want to convert that to pmol/L:

354ng/L divided by 1.355 = 261.25pmol/L

If it was 354pmol/L and we wanted to convert to ng/L:

354pmol/L times 1.355 = 479.67ng/L

Even I c*cked up in my previous reply, I put 394 instead of 354, I have this problem of my fingers doing something different on the keyboard than my brain is telling it to 🙄. I'll edit it to avoid confusing anyone else 😂

Polo22 profile image
Polo22 in reply toSeasideSusie

That's great, yeah my hands are same, quite often, of course don't think that would stand up in court as a defence 😂 when I throttle some bugger, 😇. Now what about nmol/L to ug/L ? Or will that make you scream

SeasideSusie profile image
SeasideSusieRemembering in reply toPolo22

Now what about nmol/L to ug/L ? Or will that make you scream

Which is this for? Not seen that for B12.

PS - I failed my maths but that was back in 1963 when it was GCEs, I think I'd be lost with what they teach in senior school now 😮

Polo22 profile image
Polo22 in reply toSeasideSusie

it was Serum folate, just being cheeky, 😆 I got put in lower sets for exams in school because I refused to do French , so I was to do CSE's my kids laugh " never heard of them" grade 1 CSE was equivalent to a pass at C for GCE. only ever got grade 2 , several attempts because I worked out answers in my head and couldn't explain how.

SlowDragon profile image
SlowDragonAdministrator

TSH 8.9 0.27 - 4.20

T4 total 106.0 66 - 181

Free T4 17.2 12.0 - 22.0

Free T3 3.11 3.1 - 6.8

FT4: 17.2 pmol/l (Range 12 - 22)

Ft4 only 52.00% through range

FT3: 3.11 pmol/l (Range 3.1 - 6.8)

Ft3 really terrible at just 0.27%

Shows under medicated and very poor conversion rate

How much levothyroxine are you currently taking

Do you always get same brand levothyroxine at each prescription

See GP for 25mcg dose increase in levothyroxine

Retest thyroid levels 6-8 weeks after dose increase in levothyroxine

Polo22 profile image
Polo22 in reply toSlowDragon

Hi SlowDragon , was impressed with service from Bluehorizon, ordered kit late Thursday very late, Arrived Saturday, did test Monday morning, posted before 10. Results came through earlier today. So currently on 125mcg, been on that dose a while now. Moved pharmacy several years ago when it started to be a problem getting Actavis, the one I moved to managed for a while to keep getting it. Now the 100mcg is Accord and as you told me the 25mcg is Northstar (Teva). Can't remember but have had various random brands, sometimes different from one px to next. I don't think I ever get both tablets same brand.

SlowDragon profile image
SlowDragonAdministrator in reply toPolo22

Accord (previously Actavis) don’t make 25mcg tablets

Accord only make 50mcg and 100mcg tablets

Also boxed as Almus via Boots or Northstar via Lloyds

But BEWARE Northstar 25mcg is Teva

As you need dose increase anyway you’ll likely be on 150mcg anyway

But if needed 125mcg again in future, request 50mcg tablets and cut in half to get 25mcg dose

Polo22 profile image
Polo22

Thanks , I'll try to get appointment with GP tomorrow, easier said than done.

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