Advice appreciated :) : Hi everyone again... - Thyroid UK

Thyroid UK

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Advice appreciated :)

Marinaaa profile image
10 Replies

Hi everyone again, hope you are all well :)

Here are my latest results after increasing my levo dose from 100 to 111 (100 4xweek and 125 3xweek). I got a big change in numbers.

I´m sleeping now.

Gluten free diet for three months now, trying to improve ferritin which was 27, although doing that on my own without endo support. Similar for vitD.

I also take selenium, vit B, magnesium, vit K, vit C.

These are my results. I guess FT4 is too high compared to ft3.

I also got Rt3 results this time. I don´t have a clue in their interpretation.

I did these test privately after 7 weeks ago having a TSH of 4 and Ft4 in 1.2ng/dL (0,8-2.10) my endo said I shouldn´t increase levo because I was risking arrithmia and ostheoporosis.

I would like to ask, in your opinion, is it dangerous to have too high of a FT4? is it bad for health? I understand adding t3 would perhaps be better, but at the moment it doesnt seem as an option to me as I can´t get a prescription, so I´m hoping to improve conversion by improving vitamins, minerals.....

TSH 0,29 (0,3-4,2)

T4 10,1 ug/dL (5,5-11)

FT4 1.9 ng/dL (0,6-1.1)**** other/previous lab range (0,80-2.10)

T3 0,9 ug/L (0,7-2)

FT3 2.99ng/L (2,1-4,4)

RT3 0,21ng/mL (0,09-0,35)

****this range is very strange, usual range is (0,80-2.10) but this test were done by a different lab. Lab range out of date?? I´m not feeling hyper or anything.

Ac anti Tiroglobuline 3.9 UI/mL

Ac. anti Peroxidasa (TPO) 300 UI/mL

Tiroglobuline antibodies have dissappeared thanks to the gluten free diet. I had already reduced them in the last year by eating gluten only for breakfast.

Iron 81 ug/dL (50-160)

Ferritin still at 27ng/ml (15.00-300)

Transferrin 312mg/dL (190-400)

Transferrin saturación 20% (20,00- 45,00)

Hemoglobine 12.60 g/dl (11.90-18)

H.C.M 25,70pg (26.00-33.00)

One month now on iron supplementation but, according to these results, my endo believed in february I don´t need supplementing.

vit D 45,97ng/mL deficient minus 10

insuficient 10-30

sufficient 30-100

toxic more than 100

I have improved a bit, months ago it was around 30ng/mL.

Advice appreciated. Thanks lovelies,

Marina

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Marinaaa
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greygoose profile image
greygoose

Your FT4 is only slightly over-range, and your FT3 - the most important number - is rather low. So, no, I don't think there's any danger from those results. Blood tests are only a rough guide, anyway, and the top of the range is not a cast-iron barrier, just an indication that the majority of people have a level lower than that.

Ranges vary from lab to lab, according to the machine they use to do the analysis. So, it's not an out-dated range, just the range for that lab's machine.

rT3 is a pretty useless test. It doesn't give you any information that you can't get from other tests. It will tell you if your rT3 is high, but it won't tell you why. And there are many, many reasons for high rT3, and only one of them has anything to do with thyroid. And yours is well in-range, so it doesn't tell us anything at all.

The fact that your antibodies have reduced is also meaningless. Antibodies fluctuate all the time. But, even if you got rid of them altogether, you'd still have Hashi's. That doesn't go away. And, the antibodies are the result of the disease, not the cause of it. Huge discussion on that the other day:

healthunlocked.com/thyroidu...

Doesn't start off as a discussion about antibodies, but ends up that way.

I'm afraid I can't comment on your ferritin - although obviously it's low - but maybe humanbean can help? :)

Marinaaa profile image
Marinaaa in reply togreygoose

Hi greygoose :) With regard to antibodies, I believe that if they get reduced it´s because there´s less autoinmune flare in the body and therefore they are not needed. I don´t think you can manipulate them. At least not with vitamins. If they are a result of the process of thyroid cell destruction and they are reduced, I believe there must be less destruction.We talked the other day about selenium too.

So far, selenium hasnt made a change for me.

greygoose profile image
greygoose in reply toMarinaaa

Yes, I think you're right. Reducing them artificially- if, indeed, that is possible - does not reduce attacks on the thyroid, it's the other way round. But you said you think you reduced them with your gluten-free diet. So, it's a bit confusing. :)

Marinaaa profile image
Marinaaa in reply togreygoose

Yes it´s not cause-effect, I was summarising. 😇

Marinaaa profile image
Marinaaa in reply togreygoose

That would be lovely if humanbeing could give me his opinion on iron. I´ve been reading some information he posted about the complexity of iron.I believe I´m iron deficient but Im not an expert so I have doubts.

greygoose profile image
greygoose in reply toMarinaaa

Humanbean is a lady. And she's replied to you below. :)

humanbean profile image
humanbean

Ferritin still at 27ng/ml (15.00-300) 4% of the way through the range

Transferrin 312mg/dL (190-400) 58% of the way though the range

Transferrin saturación 20% (20,00- 45,00)

Optimal results are given on this link :

rt3-adrenals.org/Iron_test_...

Ferritin --- Optimal for this for many of us is roughly mid-range or a little bit over i.e. about 160 - 200 given the range you've supplied. Your ferritin (iron stores) is far too low suggesting that you need more iron.

Transferrin Saturation (TS) --- The reference range for Transferrin Saturation usually goes up to about 50% with optimal given as 35% - 45%.

However the range given for TS in your test (20% - 45%) is rather lower than usual, suggesting that the optimal should be a little bit lower for your test as well. On a pro-rata basis I would suggest optimal for you should be, very approximately, about 30 - 40. In either case, your result of 20% is too low, and you need more iron to raise it.

Transferrin --- According to the link I gave above :

Low in range indicates lack of capacity for additional iron

High in range indicates body's need for supplemental iron

Your result is fairly close to mid-range, suggesting that your result is not miles from optimal. It is slightly over range, suggesting that you do have capacity for more iron, but not by very much.

It is not uncommon to have contradictory results, so the fact that the message from your transferrin is a little bit less certain than the other two is not a problem, so I wouldn't worry about that and would just say that you need more iron.

However, before saying that for certain I would prefer to see a serum iron result as well as the ones above. Do you have such a test result?

The thing is that with low ferritin people can have low, "normal", or high serum iron and which combination you have tells you different things.

If you have high serum iron for example, supplementing iron can continue to push serum iron even higher while ferritin hardly changes. This isn't a healthy situation to be in.

One month now on iron supplementation

What kind of iron supplement are you taking? What iron content does it have and how many times a day do you take it? Do you take your thyroid hormones at least four hours away from iron? Iron can block absorption of thyroid hormones.

When taking iron supplements taking high dose vitamin C (1000mg) at the same time can aid absorption of the iron. If iron gives you constipation you can increase your vitamin C dose to reduce the problem.

I should point out that many people struggle to absorb iron. Healthy people with healthy digestion can raise iron from being too low to being well into the range in 4 - 6 months. But there are other people, like me for example, who take much, much longer.

Your one month of iron supplementing is unlikely to have made much headway in improving your iron and ferritin.

I had below range serum iron and low in range ferritin. I was prescribed maximum dose of ferrous fumarate 210mg, and I had to take that dose for 21 months to get just my ferritin up to optimal. My serum iron was still low, and I let it stay that way. If I'd pushed my iron intake higher I would have improved my serum iron while my ferritin would have ended up going over range. So I aim to keep my ferritin at mid-range and let my serum iron do what it wants. I take a maintenance dose of my supplement and still do an iron panel test a couple of times a year. I tested more often than that in the early days so I could understand more about how my levels reacted to supplementing.

Marinaaa profile image
Marinaaa in reply tohumanbean

Hi humanbeing😀 thanks for taking your time in reading my post and answering to me.

Yes I do have iron serum results. It´s 80 (range 50,00-160.00).

And my hemoglobin is 12,60(11.90-18) HCM 25,70pg (26- 33) I have a complete blood panel done. If its important I can add it all.

I often eat quality beef and lately started eating liver once a week however my serum iron nor ferritin changed at all, which I don´t quite understand. In the past, before being diagnosed hashimoto, I used to have even lower serum iron and a ferritin around 50. And some years ago, when I started supplementing iron, I rose my levels of ferritin to 50, and that took me around three-four months, and I stayed there. My doctor used to recommend iron then. I dont understand why now, with same levels, she doesn´t.

Well, I started taking tardyferon which is sulfato ferroso 80mg, once a day with vitC, generally with lunch, or mid-evening without food.

But as it was making me constipated and this is really inconvenient to me, I bought some others in the pharmacy (which cost like 20 times more) , and I´m combining them all, one day I take tardyferon, next day the other iron, and so on...

So the others are Ferplex ( proteinsuccinilato equivalent to 40mg iron) and Fisiogen forte which is more stomach-friendly (pirofosfato iron in liposomes 30mg iron)

I´ve never had more than once a day. And I used to have it without food in the past, together with vitC or a juice. I heard that this helps absortion, but it is a bit annoying to remember it every day. Its more convenient to take it with lunch.

I find a bit confusing the fact that ferritin is very low but transferrin is nearly ok. To me, getting ferritin only up to 100 is going to take a lot of effort... I believe... In my blood tests, it also appears I have high protombin time. I´ve always had many unexplained bruises in legs and physiotherapists always point out my blood circulation isnt good but I´ve never had any pain.. i don´t know if this is somehow related to iron, or even to thyroid.

I dont know if its a question of saving money prescribing (even though tardyferon is pretty cheap) or if my doctor and my endo really dont see a need in rising ferritin.... but it is a bit shocking learning that I should have it over 100 and they dont see that..

🙃

humanbean profile image
humanbean in reply toMarinaaa

Yes I do have iron serum results. It´s 80 (range 50,00-160.00) 27% through the range

According to that link for optimal iron results that I gave earlier serum iron should be about 55% - 70% of the way through the range, which translates to a level of roughly 110 to 127, so quite a bit more than your level is currently.

I agree that it is confusing, and I can't explain why some people have inconsistent results and some don't. It could be genetics, it could be the result of inflammation, it could be an infection, it could be dietary.

The important thing when taking iron supplements is to make sure that none of the results go haywire. I've given a couple of examples of what can go wrong in this thread :

healthunlocked.com/thyroidu...

However, when you look at all your results together, it is clear that you would probably benefit from having more iron. For information on options for supplementing see this reply to another member - ignore the pregnancy stuff!

healthunlocked.com/thyroidu...

I don't know where you live and what options you have for buying over the counter or online. You might be able to source some iron supplements without prescription on Amazon UK or Ebay UK and have them delivered to wherever you live - but I'd make sure that the seller will deliver to your country before paying.

Always be aware that the iron content of any supplement is the most important piece of info you need.

Marinaaa profile image
Marinaaa in reply tohumanbean

thanks a million. I´ll work my socks up 👍

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