My results for Hashimotos- would I benefit from NDT over Levo?

[HashiDaz]

My results for Hashimotos- would i benefit from NDT over Levo? Note this would be my first ever thyroid replacement hormone.

THYROID STIMULATING HORMONE * 16.30 mIU/L 0.27 - 4.2

FREE THYROXINE * 10.6 pmol/l 12.0 - 22.0

25 OH Vitamin D * 44 nmol/L 50 - 200

Interpretation of results:

Deficient <25 nmol/L

Insufficient 25 - 49 nmol/L

Normal Range 50 - 200 nmol/L

Consider reducing dose >200 nmol/L

TOTAL THYROXINE (T4) * 56 nmol/L 59 - 154

FREE T3 4.7 pmol/L 3.1 - 6.8

Thyroid Peroxidase Antibodies * 320.0 IU/mL 0 - 34

Thyroid microsomal antibody assays using

semi-quantitative agglutination titres are no

longer available, and the more specific and

quantitative assay for antibodies to thyroid

peroxidase will now be the only assay used.

These assays are clinically equivalent and have

been offered in parallel for several years

EBNA IgG antibody * >600 U/ml (< 5 U/ml Negative)

EBV Early Ag ab.(IgG) 7.1 U/ml Borderline: 10 - 40

Negative

Result from Referral Laboratory ID (900).

EBV VCA ab.(IgM) <10 U/ml (<20 U/ml Negative)

T.I.B.C * 79 umol/L 41 - 77

TRANSFERRIN SATURATION * 19 % 20 - 55

LDH * 227 IU/L 135 - 214

CK * 164 IU/L 26 - 140

Whole Blood Chromium <1.0 ug/l < 1

Whole Blood Potassium REPORT TO FOLLOW

Whole Blood Calcium 60.2 mg/l 48 - 65

Whole Blood Copper 0.90 mg/l 0.8 - 1.65

Whole Blood Magnesium 31.9 mg/l 29 - 42

Whole Blood Manganese 8.4 ug/l 7 - 11

Whole Blood Zinc 6.3 mg/l 4.0 - 7.6

Whole Blood Selenium *353 ug/l 85 - 200

Methylmalonic acid - Serum 0.13 umol/l < 0.29

Less than 0.29 does not indicate B12 deficiency.

0.29-0.70 suggests possible B12 deficiency.

Greater than 0.70 consistent with B12 deficiency.

MMA assay may be invalidated in the presence of

renal disease. Please correlate clinically.

This test is performed on an analyser that has

been verified but awaiting accreditation by UKAS

Result from Referral Laboratory ID (898).

HCT 0.369 0.33 - 0.45

MCHC (g/L) 336 g/L 300 - 350

Red cell folate 616 nmol/L 285.4 - 1474.7

<340 nmol/L is associated with folate deficiency.

Intrinsic Factor antibodies <1.0 U/ml Normal: <6 U/ml

Gastric Parietal cell Ab Positive, Titre 1:40

Sonic Healthcare eview.tdlpathology.com/dll/......

2

FERRITIN 45 ug/L 13 - 150

Optimum Ferritin level for females : >27 ug/L

Endo suggested the following -

i) Vitamin D3 5000 units one daily.

ii) Womens multi essentials once daily (makes the urine bright yellow).

iii) Methyl complex one tablet twice daily contains Vitamin B12.

iv) Advanced EPA Eskimo oil fish oil capsules one twice daily.

v) Quercetin – take as directed

vi) Curcumin Megasorb – take as directed

below supplements to help with stress response.

i) HPA Control one tablet twice daily.

ii) Melissa/theanine one capsule twice daily.

iii) Energy multiplex one tablet twice daily – targeted supplements to support the adrenals. Take one capsule with food three times a day.

iv) Cytoquel – reduces inflammatory mediators associated with stress (in one study, this product resulted in 44% improvement in sleep quality without sleep aids). Take three capsules once per day with a meal. Sensitive patients may start with one capsule per day with a meal for the first week, and then move up to three capsules per day in week two and beyond.

Further supplements for gut may be suggested following receipt of stool tests.

[SeasideSusie Remembering]

HashiDaz

My results for Hashimotos- would i benefit from NDT over Levo? Note this would be my first ever thyroid replacement hormone.

Not necessarily. It's much better to start on Levo, it's cheap and prescriptions will be free. NDT is unlikely to be prescribed on the NHS and to self source it isn't necessarily easy and can be expensive. Levo suits the majority people, it's the minority that don't do well on it and are on this forum.

Most doctors dismiss antibodies as being of no importance and know little or nothing about Hashi's and how it affects the patient, test results and symptoms. You need to read, learn, understand and help yourself where Hashi's is concerned.

Some members have found that adopting a strict gluten free diet can help, although there is no guarantee.

Gluten contains gliadin (a protein) which is thought to trigger autoimmune attacks so eliminating gluten can help reduce these attacks.

You don't need to be gluten sensitive or have Coeliac disease for a gluten free diet to help.

Gluten/thyroid connection: chriskresser.com/the-gluten...

stopthethyroidmadness.com/h...

stopthethyroidmadness.com/h...

hypothyroidmom.com/hashimot...

thyroiduk.org.uk/tuk/about_...

Supplementing with selenium l-selenomethionine 200mcg daily can also help reduce the antibodies (although your current selenium level is over range so it isn't a good idea to supplement at this stage), as can keeping TSH suppressed.

Hashi's and gut absorption problems tend to go hand in hand and can very often result in low nutrient levels or deficiencies.

You have a low Vit D level but you also need to test

Ferritin

B12

Folate

25 OH Vitamin D * 44 nmol/L 50 - 200 = 17.6ng/ml

This is low. The Vit D Council recommends a level of 125nmol/L (50ng/ml) and the Vit D Society recommends a level of 100-150nmol/L (40-60ng/ml).

To reach the recommended level from your current level, based on the Vit D Council's suggestions you could supplement with approx 5,000iu D3 daily

vitamindcouncil.org/i-teste...

Retest after 3 months.

As you have Hashi's then for best absorption an oral spray is recommended, eg BetterYou, or sublingual drops, eg Vitabay Organics, as these bypass the gut.

Once you've reached the recommended level then you'll need a maintenance dose to keep it there, which may be 2000iu daily, maybe more or less, maybe less in summer than winter, it's trial and error so it's recommended to retest once or twice a year to keep within the recommended range. You can do this with a private fingerprick blood spot test with an NHS lab which offers this test to the general public:

vitamindtest.org.uk/

There are important cofactors needed when taking D3 as recommended by the Vit D Council -

vitamindcouncil.org/about-v...

D3 aids absorption of calcium from food and K2-MK7 directs the calcium to bones and teeth where it is needed and away from arteries and soft tissues where it can be deposited and cause problems such as hardening of the arteries, kidney stones, etc.

D3 and K2 are fat soluble so should be taken with the fattiest meal of the day, D3 four hours away from thyroid meds if taking tablets/capsules/softgels, no necessity if using an oral spray

Magnesium helps D3 to work. We need Magnesium so that the body utilises D3, it's required to convert Vit D into it's active form. So it's important we ensure we take magnesium when supplementing with D3.

Magnesium comes in different forms, check to see which would suit you best and as it's calming it's best taken in the evening, four hours away from thyroid meds if taking tablets/capsules, no necessity if using topical forms of magnesium.

naturalnews.com/046401_magn...

thefamilythathealstogether....

drjockers.com/best-magnesiu...

Check out the other cofactors too (some of which can be obtained from food).

T.I.B.C * 79 umol/L 41 - 77

TRANSFERRIN SATURATION * 19 % 20 - 55

Over range TIBC and below range Transferrin saturation. These may indicate that you need iron supplementation. This is only part of the iron panel, ferritin and serum iron are also needed. You can see what optimal levels of an iron panel are here

web.archive.org/web/2018083...

[HashiDaz in reply to SeasideSusie]

Thank you so much SeasideSusie - note i have updated my posts to include other results. he also mentioned the following -

3. Micronutrients – she has very low Vitamin D level of 44 nmol/L and I have recommended high strength Vitamin D3. Additionally, her ferritin is sub-optimal particularly in the context of hair loss and I have suggested iron supplements. She prefers over the counter preparations in the first instance and I have advised her to take this at a different time to other medications and supplements. Her methylmalonic acid level was not elevated but she has weakly positive gastric parietal cell antibody of 1:40. The latter can be associated with hypochlorhydria and reduced B12 absorption. I will await with interest the results of the stool test in the first instance, but it is also important for her to report problems such as early satiety, nausea, and unexplained weight loss. Under those circumstances an OGD might be required. Her red cell selenium is elevated – 353 (85-200) and I will adjust her supplement program that she had been taking prior to her seeing me so that she is not taking too much selenium.

4. She has been having muscle pains over the left shoulder and thigh. Her CK is mildly elevated – 164 and LDH mildly elevated at 227. Renal and liver function were normal. Her inflammatory markers were not raised. I will repeat the CK and if it is persistently elevated/getting worse I will arrange an EMG for her +/- an MRI scan. We might also need to consider onward referral to a rheumatologist.

5. Her LH was 7.2, FSH 2.8, total testosterone 1.2, oestradiol 357 pmol/L. Thus, her testosterone level is not significantly elevated.

6. The salivary cortisol profile showed high level on waking and also late morning. The findings are suggestive of a stress response if not fluctuations in blood glucose. Her fasting glucose is 4.7, TG 0.8, uric acid 238 umol/L. Thus, although her fasting glucose is normal, I think she might benefit from a ketogenic diet particularly with a view to targeting symptoms that might be attributable to fluctuations in blood glucose. I will send her details of this. Of note, she does not have the genetic susceptibility for coeliac disease.

[SeasideSusie Remembering in reply to HashiDaz]

He seems very thorough.

ii) Womens multi essentials once daily (makes the urine bright yellow).

It's B2 (Riboflavin) that turns urine bright yellow.

Check the ingredients for your Womens multi essentials - assuming this is the NutriAdvanced supplement then it contains 200mcg iodine and 55mcg selenium. Iodine should only be supplemented if tested and found to be deficienct. It used to be used to treat hypERthyroidism so can make hypOthyroidism worse and it's definitely not recommended when Hashi's is present.

[HashiDaz in reply to SeasideSusie]

Ok Will do, i have been supplementing with Sea Kelp since last Aug, he has asked me to take one a day instead of two as Women's Health has iodine. What else is Iodine called on a blood test? i will look to see if it was tested.

[SeasideSusie Remembering in reply to HashiDaz]

Just serum iodine, or iodine blood test, as far as I know.

Why did you start taking Sea Kelp?