Are you on thyroxine replacement ? Your thyroid levels seem ok- but high TG and low tpo is unusual and usually points more to hyperthyroid but u can have a mixture of both or none with autoimmune thyroidits.
You said you are not on any supplements -
High ferritin can also be a sign of inflammation or post infection. Your body is storing it’s iron because it may be fighting infection.
However your b12 is very low! Do you have any symptoms of b12 deficinecy? If you do-especially neurological ones- you need loading injections ASAP. Trust me it’s amazing how much it can affect u.
B12, iron, and folate all work together in a complex interaction. Your folate is on the lower side of normal too- u can take 400ug daily alongside b12 supplements. (But get loading injections first)
Your vit D is also only JUST sufficient. Better to aim for above 100 to really feel well. Supplementing 1-3000iu daily can help (do take magnesium And vit k2mk7 co factors with your vit D to help absorb properly)
If you sort your vitamins out you may find other things fall into place. However with high ferritin they may need to do liver checks also. Discuss with your Gp x
Thanks Saya85 in the past I have been told I have fatty Liver (have two to three drinks a week with a meal ;-00 How come my B12 is low as it looks in range and yes I do have weird neurological things going on as well as on heck of an aching body!! Off to see a functional Meds Dr soon. Hoping he can sort me out been on Levo for 16yrs now on 75mg and last year discovered I have Hashimotos
Ahh yes- a lot of us hashis have cholesterol and liver issues. Haemochromatosis is excessive iron. Some people are prone to storing excess iron also so maybe worth rechecking liver tests again. And actually checking serum iron levels not just ferritin. Transferring and full blood count is useful too.
Your b12 is not in range? You’ve written 109. And the ‘normal’ range is 140- 724.
You are deficient. But most current thinking says that b12 ranges need to be above 400 for us to feel anywhere near good. You can have symptoms of lower than 400.... I imagine you must be symptomatic. (Pls see online list of b12 and vit D deficiencies- vit D is a hormone and affects over 300 processes in body)
Are you vegetarian? Do you eat plenty of animal fats and meats?poor Diet can reduce b12. If the answer is no- you may want to ask doctor to test you for pernicious anaemia tests to rule out what’s causing the very low results. Hypothyroid px’s are prone to b12 deficinecy (could be stomach acid related and poor protein breakdown)
Iron folate vit D and b12 are all needed For good t4 to t3 conversion- so def worth getting them optimised. Your thyroid tests may improve thereafter also. You could prob go up by 25mcg to raise ur t4/t3 levels but I would sort vitamins out first. It might be a combination of t4/t3 supplementation is needed
Thanks just wondering what the difference is between B12 range you mentioned and the test result I had was ACTIVE B12 is that the same thing? I notice the range on Medichecks for active B12 should be 25.10 -165.00 which would indicate that my reading 109.00 is within limits for that result ? There are no asterixes here either.Rather confusing ??
With the range you've provided, the result you have is a serum B12 result. Active B12 usually has a top of range of about 160 or thereabouts (from memory).
Has medichecks got their knickers in a twist about something? They seem to be making it unclear whether they are providing serum B12 results or Active B12 results.
humanbean medichecks generally mention active b12 tests. My recent one showed that.
Jaxzz- I think you’re confusing the two. Serum b12 shows the amount of b12 in blood, active b12 shows the amount of b12 actually available to the cells. You cannot interchange the two values.
I am quoting your above results from original post(which appears to be serum b12)-
109 is below the normal range they provided themselves of 140-740
You cannot use that 109 value and apply it to a different range (I.e active range)
If your serum is that low your active b12 must certainly be deficient. (Not true the other way round)
If your original post values are true/ then u are definitely deficient. Did they ask u to repeat the b12 again? They won’t always flag up a deficinecy as they would suggest increasing your diet and restesting later
Your Thyroid results suggest you may be under medicated, your TT4 and FT4 could be higher, FT3 is low. But your GP is unlikely to agree to dose increase in Levo due to low TSH
Dr Toft, past president of the British Thyroid Association and leading endocrinologist, states in Pulse Magazine,
"The appropriate dose of levothyroxine is that which restores euthyroidism and serum TSH to the lower part of the reference range - 0.2-0.5mU/l.
In this case, free thyroxine is likely to be in the upper part of its reference range or even slightly elevated – 18-22pmol/l.
Most patients will feel well in that circumstance. But some need a higher dose of levothyroxine to suppress serum TSH and then the serum-free T4 concentration will be elevated at around 24-28pmol/l.
This 'exogenous subclinical hyperthyroidism' is not dangerous as long as serum T3 is unequivocally normal – that is, serum total around T3 1.7nmol/l (reference range 1.0-2.2nmol/l)."
You can obtain a copy of the articles from Thyroid UK email print it and highlight question 6 to show your doctor please email Dionne at
tukadmin@thyroiduk.org
Also perhaps request the list of recommended thyroid specialists
Professor Toft recent article saying, T3 may be necessary for many otherwise we need high FT4 and suppressed TSH in order to have high enough FT3
Thanks SlowDragon yes discovered gluten intolerance about a year ago and antibody readings are lower this year and feeling somewhat better re brain fog and few other areas and now struggling with incredible aching on what seems to be muscle/tendon areas at hip and shoulder joints. Am booked in to see Functional Meds Dr soon hence my blood tests.Hoping he will sort my T3 levels naturally and get to the root of my raised iron levels. Apologies for confusion I thought it quicker to copy and paste last years results and update numbers.(unfortunately didn't notice the B12 was a different test result ;-0
Your high ferritin is very concerning because it indicates iron overload, which can damage your liver, heart, pancreas, joints, and lead to organ failure. I see that you have liver issues, as well as an aching body and joint and tendon pain. These symptoms could very well be caused by your iron overload. It's very important to get tested for Hemochromatosis to see if this is the cause of your high ferritin.
Ingesting high amounts of vitamin C causes increased uptake of iron from all foods. Do you happen to take a lot of C? What are your periods like? A monthly period can hold the symptoms of Hemochromatosis (if this is the cause of your iron overload) off for many years, but once those periods slow down or stop, then symptoms arise, leading to eventual diagnosis.
Hi shootingastars thanks yes I am concerned and going to see Functional meds Dr tomorrow with test results and questions. I’m 63yrs so no monthlies lol I do not take Vitamin C only eat what I see is a good healthy diet Veg proteins and fruits . Struggling with my weight so tomorrow I am hoping there’s a way forward and will ask about test for Hemochromatosis . Do you have a medical background?
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