Hello Everyone , we finally have both sets of results for you to see NHS and Private , we really would like your thoughts because my husbands depression isn't getting any better. The NHS blood test was just the TSH level and that was 0.38 mIU/L ( normal ) .
Medichecks Results are:-
CRP HS 0.39mg/L
Ferritin 188ug/L
Folate serum 4.84ug/L
Vitamin B12 Active 130000 pmol/L
Vitamin D 52.2nmol/L
TSH 0.582mIU/L
Free T3 4.96pmol/L
Free Thyroxine 18600 pmol/L
Thyroglobulin Antibodies 360000kU/L
Thyroid Peroxidase Antobodies 14.7 kIU/L
Well all your thoughts please , and we would like to know if you think seeing an endocrinologist would be worth while . Thanks everyone .
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Homeswoman
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Can you add the respective reference ranges to each result, as they vary from lab to lab; and also check those three very large numbers for missing commas or decimal points.
This is low, it would be better in double figures. Further suggestion can be made when we see a correct B12 result.
Vitamin D 52.2nmol/L (20.88ng/ml)
This is low. The Vit D Council recommends a level of 125nmol/L (50ng/ml) and the Vit D Society recommends a level of 100-150nmol/L (40-60ng/ml). To reach the recommended level from current level, the Vit D Council suggests taking 3,700iu D3 daily
Personally, as it's so close to the lower limit of that category I would go for 5,000iu daily.
Retest in 3 months.
When you've reached the recommended level then you'll need a maintenance dose to keep it there, which may be 2000iu daily, maybe more or less, maybe less in summer than winter, it's trial and error so it's recommended to retest once or twice a year to keep within the recommended range. You can do this with a private fingerprick blood spot test with an NHS lab which offers this test to the general public:
D3 aids absorption of calcium from food and K2-MK7 directs the calcium to bones and teeth where it is needed and away from arteries and soft tissues where it can be deposited and cause problems such as hardening of the arteries, kidney stones, etc.
D3 and K2 are fat soluble so should be taken with the fattiest meal of the day, D3 four hours away from thyroid meds if taking tablets/capsules/softgels, no necessity if using an oral spray
Magnesium helps D3 to work. We need Magnesium so that the body utilises D3, it's required to convert Vit D into it's active form. So it's important we ensure we take magnesium when supplementing with D3.
Magnesium comes in different forms, check to see which would suit you best and as it's calming it's best taken in the evening, four hours away from thyroid meds if taking tablets/capsules, no necessity if using topical forms of magnesium.
Now that we know there is no problem with B12, supplementing to raise folate level could be considered. Eating lots of folate rich foods may help, but if not then taking a good B Complex containing methylfolate will help, but choose one without too much methylcobalamin (B12) as that doesn't really need raising. If you can find one with 400mcg melthylfolate that should be enough. The idea of taking a B Complex is that it keeps all the B vitamins in balance.
TSH 0.582mIU/L (0.27 - 4.2)
Free Thyroxine 18.6 pmol/L (12-22)
Free T3 4.96pmol/L (3.1-6.8)
These are euthyroid (normal), all within range, they don't suggest either hypothroidism or hyperthyroidism.
Thyroglobulin Antibodies 360kU/L
(<115)
These are high, there are a few reasons for raised Thyroglobulin antibodies. They can sometimes indicate autoimmune thyroid disease (Hashimoto's) even when Thyroid Peroxidase antibidoes are negative. However, because there are other reasons for raised thyroglobulin antibodies (and I don't know them) it may be worth discussing with the GP.
I made a suggestion for Vit D in my previous reply.
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