Latest Results Advice Please

Inflammation

CRP HS - 3.39 mg/L (Range: 0 - 5)

Iron Status

Ferritin 72.8 ug/L (Range: 13 - 150)

Vitamins

Folate - Serum X - 3.80 ug/L (Range: > 3.89)

Vitamin B12 - Active - 77.9 pmol/L (Range: 37.5 - 150)

Vitamin D - 65 nmol/L

Thyroid Hormones

TSH - 1.44 mU/L (Range: 0.27 - 4.2)

Free T3 - 4.84 pmol/L (Range: 3.1 - 6.8)

Free Thyroxine - 16.4 pmol/L (Range: 12 - 22)

Autoimmunity

Thyroglobulin Antibodies X 212 IU/mL (Range: < 115)

Thyroid Peroxidase Antibodies X 141 IU/mL (Range: < 34)

I was increased to 100mcg levothyroxine on 15th Feb.

I still have symptoms. Mainly constipation, fatigue, inability to lose weight and just general feeling depressed and down.

Previous medichecks results on 75mcg -

TSH - 2.21 mu/L (0.27 - 4.2)

T3 - 5.3 pmol/L (3.1 - 6.8)

T4 - 16 pmol/L (12 - 22)

My Ferritin was 9 at diagnosis in Oct so that's much better.

Vitamin D was severely deficient and was on loading dose and now taking 3000 per day.

I am taking B12 and have just added in B complex which contains folate so hopefully that will raise my low folate.

In your wise opinion do I have room for a dose increase and to battle the GP for one who has been happy with my results since I was on 75mcg lol. He has agreed to an increase every time so far but we shall see this time. Wanna be sure before I push for one. Am due bloods at GP in couple weeks.

Thanks

[SlowDragon Administrator]

Was test done as recommended, early morning, ideally before 9am and last dose levothyroxine 24 hours before test

FT4: 16.4 pmol/l (Range 12 - 22) 44.00%

FT3: 4.84 pmol/l (Range 3.1 - 6.8) 47.03%

Helpful calculator for working out percentage through range

thyroid.dopiaza.org

Suggest you push for small increase to 125mcg and 100mcg on alternate days (or cut tablets to get 112.5mcg daily)

Which brand of levothyroxine are you currently taking

Do you always get same brand

[Hidden in reply to SlowDragon]

Yes done under conditions recommended on here. I'm on Accord and mostly they give me same brand now.I'm definitely going to push for an increase as I still feel rubbish and I've worked on ferritin, D and B12 and feel the same lol

[SlowDragon Administrator in reply to Hidden]

Accord don’t make 25mcg tablets. So request 50mcg and cut in half to get 25mcg or cut in 1/4 to get 12.5mcg

As you have Hashimoto’s, if not already on strictly gluten free diet……have you had coeliac blood test done

If not, request Coeliac test BEFORE considering trialing strictly gluten free

[SlowDragon Administrator in reply to Hidden]

nice.org.uk/guidance/ng20/c...1.1 Recognition of coeliac disease

1.1.1 Offer serological testing for coeliac disease to:

people with any of the following:

persistent unexplained abdominal or gastrointestinal symptoms

faltering growth

prolonged fatigue

unexpected weight loss

severe or persistent mouth ulcers

unexplained iron, vitamin B12 or folate deficiency

type 1 diabetes, at diagnosis

autoimmune thyroid disease, at diagnosis

irritable bowel syndrome (in adults)

first‑degree relatives of people with coeliac disease.

[Buddy195 Administrator]

I’d definitely push for an increase Eternity84, but as SlowDragon suggests, I’d recommend increasing slowly.

If I needed to add 25mcg Levo, I’d add 12.5mcg alternate days at first, then daily, then slowly add another 12.5mcg so the increase totals 25mcg. For me, slow & steady is the way to go with both dose increases (or decreases) as I seem to be very sensitive to changes. Very best wishes.