Results concerning me

[Pollyerrington]

Hi,

So I managed to get 5 years worth of blood tests.

I've listed the significant items I think are worth looking at. I'd really appreciate people's interpretation of my results.

All issues on the list are linked to Hypothyroid although my recent result is TSH 2.0 (0.27-4.2)

Results:

24/10/12 - ferritin 15 (13-150)

03/10/13 - low haematocrit - 0.359 (0.36-0.46) (low throughtout last 5 years)

21/10/14 - high serum creatine - 84 (44-80) kidney. Linked to hypothyroidism

21/10/14 - ferritin 36 (13-150) - low end of scale. Linked to hypothyroidism

21/01/14 - gfr 78/ml - kidney damage

?!

03/02/15 - ferritin 29 (13-150)

03/02/15 - TSH 2.71 (0.27-4.2)

03/02/15 - FT3 4.8 (3.9-6.7)

03/02/15 - FT4 15.4 (12-22)

18/04/16 - ferritin 39 (13-150)

18/04/16 - gfr 76/ml - kidney damage

?!

18/04/16 - TPOAb 5.9 iu/ml

Internet says there seems to be a strong links between kidney issues and thyroid - although my GP has never mentioned my results regarding my kidneys (even though they were highlighted in the tests)

I have terrible brain fog sometimes, so much fatigue. Terrible sleep (restless legs and never getting a full night's sleep). Joint pain. Depression. The list goes on...

Please help!!!

Thanks in advance for your comments...

[greygoose]

The restless legs are probably due to that low ferritin. Have you never supplemented iron?

Joint pain could be due to low vit D. Have you had that tested? And how about vit B12 and folate? All very important.

Are you on any form of thyroid hormone replacement? If so, you need an increase in dose. If not, your thyroid is struggling.

You're negative for anitbodies, but one negative test does not completely rule out Hashi's.

I'm afraid I don't know much about kidneys.

[Pollyerrington in reply to greygoose]

I'm taking ferrous sulphate for my ferritin. And also B12 5000mcg.

I'm not on thyroid hormone replacement. I've previously been given completely conflicting advice on here regarding taking T3, so I'm not really sure what to do!

[greygoose in reply to Pollyerrington]

OK, well, best to take 1000 mcg vit C with your iron, to aid absorption. And a B complex with the B12 to balance the Bs.

Although your TSH is a bit high, it's not really hypo at the moment. I'm not really sure that self-medication is justified at this point. And certainly not whilst you have such low iron. It just won't help you. You need to get your nutrients up, first.

Did you have your vit D tested?

[Pollyerrington]

Hi, I'm not quite sure how to interpret your reply! Are you just confirming that kidney and hypothyroidism are linked?

As my TSH is 2.0 I can't be diagnosed as hypo... :/

[SlowDragon Administrator]

Gilberts syndrome and low GFR seem to be linked

According to goggle Gilberts syndrome and thyroid may also be linked

Vitamin d levels very important ....can you get previous results or get tested if not been done.

Antibodies - there are two sorts - TPO and TG. You can be high in either or both. Sadly the NHS never seems to check TG antibodies

Private tests can be done if GP won't agree

thyroiduk.org.uk/tuk/testin...

[Pollyerrington in reply to SlowDragon]

I had both TPO and TG. But actual TG results aren't listed. Just mentioned as 'normal'

Requesting Vit D on Friday as I have an appointment. Thank you!

[Pollyerrington]

Thank you. Will get a thermometer!

[radd]

Polly,

Your thyroid hormone results show you are euthyroid (previous post) but you appear to have many hypothyroid symptoms. This means you have enough thyroid hormone in the blood stream so have good test results but it is not getting into your cells to be activated.

Adrenal problems could cause receptor uptake problems as the adrenals hormones are intricately connected to good thyroid function. Are you menopausal or do you have difficult periods ? ? .. Do you know of any sex hormone deficiencies ? ? .. (oestrogen, progesterone, etc)

Every cell in the body has receptors for thyroid hormone and T3 (active hormone) has to get inside the cells by binding to the nuclear receptor..Thyroid receptor resistance is when thyroid hormone cannot get into the cell so causing low thyroid symptoms despite “normal” thyroid hormone levels in the body. Receptor site defects can be caused by elevations in cortisol, homocysteine, sex hormone imbalances, etc ... .

TBG (thyroxine-binding globulin is one of three proteins that binds the highest amount of thyroid hormones T4 & T3 in (blood plasma) circulation. (Others are transthyretin & serum albumin). It will become elevated with high oestrogen and bind all thyroid hormone leaving too little free to get into the cells.

High testosterone will encourage too little TBG which might leave too much free thyroid hormone circulating in the blood stream (giving you good results) but too much free hormone can shut down receptor sites and cause insensitivity meaning T3 can’t enter.

For the proper use of thyroid hormone by the body, optimal nutrients//iron & adequate cortisol levels are required in order to make make//use the enzymes that mediate all the chemical processes.

Most GP’s don't know the connection between low “active” thyroid hormone and slow kidney function. Most doctors & endos would look at your thyroid test results and say there is nothing wrong.

Ask your GP to test all sex hormones and email [e-mail] for a list of sympathetic endos//doctors that members have had positive experiences with.

Good advice re sups already given by grey goose.

.

[Pollyerrington in reply to radd]

Hi, I have heavy but short periods.

My testosterone is high as I have PCOS.

I will ask to have my sex hormones tested. Thank you so much for your input.

[Pollyerrington]

Basal temp for me is 35.9. Is that low?

[Pollyerrington]

Thanks - it was taken under the tongue. 35.9 today and yesterday. Will keep doing it.

[Pollyerrington]

Yes, you mentioned this in a different post to me last week. Autoimmune does run in my family. My grandfather had diabetes type 1, and a stroke.

You mentioned needing T3 to combat this, but I'm nervous taking T3 unnecessarily and causing myself further issues... do you know what the complications might be if I take T3 and don't have the resistance?

Thanks.