I have been taking 25mg levothyroxine for 3 weeks now (TSH 5.87 (0.35 to 6) FT4 13.78 (12-22) FT3 5 (3.1 - 6.8) TPO AB 396) blood test next week to check TSH and ESR (NHS lab will not test FT4). I will be asking doctor to increase to 50mg, happy to start very slowly as I have been known not to tolerate new drugs. On B12 injections, VIT D 58, Ferritin 71, ESR 14 (0-12). I have ME/CFS for last 16 years. Over the last few years I have been reacting to perfumes, chemicals, car fumes, burning smells, mould, newspaper print etc. I also no longer sweat at all. I have removed all chemicals from the house, now only use fragrance free. Have inhalers and daily antihistamine but do not help. Had a major crash of symptoms late November could not even use my normal fragrance free products. My long suffering husband could not even eat oranges as the smell of the juice in the air felt like acid up my nose. Have had 2 course of steroids, false saliva and antibiotic nose cream as doctor said nose was red raw and inflamed. I have not been able to leave the house for weeks, had to cancel Christmas plans. Have started to feel better since Sunday (typical wanted to see specialist when wheezing and hoarse voice) Went to see an immunologist today he said there was nothing he could do as it was not an immune problem and he did not have a switch to turn of the enhanced smell. Has anybody else had similar problems? Could it be thyroid related? Should I ask for a referral to an endroconologist? I am finding it very difficult to live like this and can only cope when staying in my house.