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Is there reason for concern that the
Xtandi
has started to fail after 21/2 years.
Is there reason for concern that the
Xtandi
has started to fail after 21/2 years.
rhome502
in
Advanced Prostate Cancer
5 years ago
enzalutamide (XTANDI®, Astellas Pharma Inc.) for patients with metastatic castration-sensitive prostate cancer (mCSPC).
On December 16, 2019, the Food and Drug Administration approved enzalutamide (
XTANDI
®, Astellas Pharma Inc.) for patients with metastatic castration-sensitive prostate cancer (mCSPC). FDA previously approved enzalutamide for patients with castration-resistant prostate cancer.
On December 16, 2019, the Food and Drug Administration approved enzalutamide (
XTANDI
®, Astellas Pharma Inc.) for patients with metastatic castration-sensitive prostate cancer (mCSPC). FDA previously approved enzalutamide for patients with castration-resistant prostate cancer.
Darryl
Partner
in
Advanced Prostate Cancer
4 years ago
How long are the 2nd generation drugs effective for? (2nd generation drugs I.e. Zytiga, Xtandi, appaludamide)
I have been told that the 2nd generation drugs (Zytiga,
Xtandi
& appaludamide) might only be effective for maybe 3 years. Is this true? Thank you for your opinion. Chris
I have been told that the 2nd generation drugs (Zytiga,
Xtandi
& appaludamide) might only be effective for maybe 3 years. Is this true? Thank you for your opinion. Chris
Christopherg
in
Advanced Prostate Cancer
5 years ago
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just finished ext beam radiation to spine now on xofigo
zytiga quite working after 6 months mo psa up to 8.13 as of 9/1 mets in bones went from 4 to 10 Mo wanted me to start
xtandi
I refused so he sent me to a radiation oncologist who did a scan and seen a very bad met on a vertebrate thank was causing pain he hit with ext beam 5 times pain went away. next
zytiga quite working after 6 months mo psa up to 8.13 as of 9/1 mets in bones went from 4 to 10 Mo wanted me to start
xtandi
I refused so he sent me to a radiation oncologist who did a scan and seen a very bad met on a vertebrate thank was causing pain he hit with ext beam 5 times pain went away. next
Racer26
in
Advanced Prostate Cancer
5 years ago
Denied for Vision Trial
While we were waiting for all the tests, his PSA went up to 530.62 so the doctor prescribed him
Xtandi
(enzalutamide) . It seems like he has more energy now. But I'm really scared how long it will last..... Will you please let me know what option will we have after
Xtandi
fail on him?
While we were waiting for all the tests, his PSA went up to 530.62 so the doctor prescribed him
Xtandi
(enzalutamide) . It seems like he has more energy now. But I'm really scared how long it will last..... Will you please let me know what option will we have after
Xtandi
fail on him?
Muzpapa
in
Advanced Prostate Cancer
5 years ago
DO I GO WITH CHEMO OR ADT DRUGS?
The doc gave me a choice of chemo or the drugs such as Erleada,
Xtandi
or Zytiga. (I have read each drug results and am leaning towards Erleada?). His advice was to go to the drugs, the nurses advice was to go to chemo, saying there are better results with early chemo.
The doc gave me a choice of chemo or the drugs such as Erleada,
Xtandi
or Zytiga. (I have read each drug results and am leaning towards Erleada?). His advice was to go to the drugs, the nurses advice was to go to chemo, saying there are better results with early chemo.
EBFJ
in
Advanced Prostate Cancer
5 years ago
Xtandi and Firmagon side effect s
I had lab work after 9 days on
Xtandi
and my PSA is now going down instead of up. Anybody had these 2 drugs do that to them?
I had lab work after 9 days on
Xtandi
and my PSA is now going down instead of up. Anybody had these 2 drugs do that to them?
xpbdb
in
Advanced Prostate Cancer
5 years ago
Peanut butter bad??
Had great run on zytiga then on trial keytruda and
xtandi
. Failure 😖 he was diagnosed 8 years ago Gleason 8. Lymph node involvement. Treated with dr snuffy Meyers who then retired. Miss him. He is going for scans today just praying not in bones.
Had great run on zytiga then on trial keytruda and
xtandi
. Failure 😖 he was diagnosed 8 years ago Gleason 8. Lymph node involvement. Treated with dr snuffy Meyers who then retired. Miss him. He is going for scans today just praying not in bones.
Judymin
in
Advanced Prostate Cancer
5 years ago
Failing Clinical Trail
He failed
Xtandi
in 9 months, failed Erleada in 3 months.
He failed
Xtandi
in 9 months, failed Erleada in 3 months.
Hidden
in
Advanced Prostate Cancer
5 years ago
Optimal chemohormonal sequencing for metastatic castration-resistant prostate cancer MAY be Taxotere->Zytiga->Jevtana->Xtandi
Alternating chemos and hormonals like this seems to be optimal for metastatic castration-resistant prostate cancer (mCRPC). Other therapies may be able to be piggybacked so they can be tried sooner. https://pcnrv.blogspot.com/2019/12/optimal-chemohormonal-sequencing-for.html
Alternating chemos and hormonals like this seems to be optimal for metastatic castration-resistant prostate cancer (mCRPC). Other therapies may be able to be piggybacked so they can be tried sooner. https://pcnrv.blogspot.com/2019/12/optimal-chemohormonal-sequencing-for.html
Tall_Allen
in
Advanced Prostate Cancer
4 years ago
Xtandi is bringing PSA down ..will the cancer stop growing ?
Xtandi
49 days on
Xtandi
.. minimal side effects other than fatigue . PSA dropped from 22 to 18 in first 20 days and we expect it to decrease regularly month by month . Down side is Bone Scan shows the t10 is now significantly effected .
Xtandi
49 days on
Xtandi
.. minimal side effects other than fatigue . PSA dropped from 22 to 18 in first 20 days and we expect it to decrease regularly month by month . Down side is Bone Scan shows the t10 is now significantly effected .
Running-on-empty
in
Advanced Prostate Cancer
5 years ago
starting xtandia
Any suggestions for beginning
xtandi
after being on zytiga for 6 months?
Any suggestions for beginning
xtandi
after being on zytiga for 6 months?
linpisarn
in
Advanced Prostate Cancer
5 years ago
FDA approves Erleada for metastatic hormone-sensitive prostate cancer
Probably
Xtandi
too very soon. https://pcnrv.blogspot.com/2019/05/two-new-advanced-hormonal-agents.html
Probably
Xtandi
too very soon. https://pcnrv.blogspot.com/2019/05/two-new-advanced-hormonal-agents.html
Tall_Allen
in
Prostate Cancer Network
5 years ago
Moving forward with treatment: Xtandi and Provenge
He's thinking
xtandi
or erleada as my dad struggles with maintaining his blood pressure and zytiga has been known to increase blood pressure.
He's thinking
xtandi
or erleada as my dad struggles with maintaining his blood pressure and zytiga has been known to increase blood pressure.
Lynsi13
in
Advanced Prostate Cancer
5 years ago
FDA-approved therapies for metastatic hormone-sensitive prostate cancer (mHSPC)
I also included
Xtandi
in anticipation of its approval soon. https://pcnrv.blogspot.com/2017/06/newly-diagnosed-metastatic-m1-but-still.html
I also included
Xtandi
in anticipation of its approval soon. https://pcnrv.blogspot.com/2017/06/newly-diagnosed-metastatic-m1-but-still.html
Tall_Allen
in
Advanced Prostate Cancer
5 years ago
FDA Approves Apalutamide for mHSPC
https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-apalutamide-metastatic-castration-sensitive-prostate-cancer Interesting,
Xtandi
got a head start from Erleada, perhaps competition will lower the cost...
https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-apalutamide-metastatic-castration-sensitive-prostate-cancer Interesting,
Xtandi
got a head start from Erleada, perhaps competition will lower the cost...
DarkEnergy
in
Advanced Prostate Cancer
5 years ago
Finally good news/PSA heading down.(first time in 13 months..Fenben? Delayed miracle from The Mayo Clinic? Ribeye steaks/chocolate sundaes?
My ALK Phos also dropped from 80 to 61) ** For the past 18 months I have been on just Lupron and
Xtandi
...I stopped doing BIRM about a year ago...and added Fenben (hookworm med for dogs as per "Joe's Protocol") and have been eating the occasional Ribeye...the occasional Chocolate Sundae...and eating
My ALK Phos also dropped from 80 to 61) ** For the past 18 months I have been on just Lupron and
Xtandi
...I stopped doing BIRM about a year ago...and added Fenben (hookworm med for dogs as per "Joe's Protocol") and have been eating the occasional Ribeye...the occasional Chocolate Sundae...and eating
greatjohn
in
Advanced Prostate Cancer
5 years ago
Advanced prostate cancer on Lupron and xtandi
Has anyone tried Diosmin and Hesperidin it is helping with Shrinking my lymph noids and taking my pain away
Has anyone tried Diosmin and Hesperidin it is helping with Shrinking my lymph noids and taking my pain away
Wen6181hellothere
in
Advanced Prostate Cancer
5 years ago
Real increase in PSA
What can i do I understand
xtandi
is a option, immuno therapy. I just went through weight loss surgury lost 40lbs eating perfect daily exercise. I hate the idea of waiting to experience pain further mets now non detectable im sure there micro Any thoughts suggestions to combat the demon cancer.
What can i do I understand
xtandi
is a option, immuno therapy. I just went through weight loss surgury lost 40lbs eating perfect daily exercise. I hate the idea of waiting to experience pain further mets now non detectable im sure there micro Any thoughts suggestions to combat the demon cancer.
Costarica1961
in
Advanced Prostate Cancer
5 years ago
Enzalutamide [Xtandi] & altered sense of Taste
KEYWORDS: Dysgeusia; Enzalutamide; Taste alternation; Timing of intake;
Xtandi
PMID: 31543773 PMCID: PMC6738168 DOI: 10.1159/000502054
KEYWORDS: Dysgeusia; Enzalutamide; Taste alternation; Timing of intake;
Xtandi
PMID: 31543773 PMCID: PMC6738168 DOI: 10.1159/000502054
pjoshea13
in
Advanced Prostate Cancer
5 years ago
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