Xtandi and cardio problems

[joeguy]

Has anyone developed tachycardia or skipped beats while on Xtandi? I started experiencing rapid heart rate a few weeks after starting Xtandi. I was put on 25mg Metoprol daily and things seemed to even out, but now after 10 months on Xtandi I am having daily irregular or skipped heart beats. They increased my dose of Metoprol to 50 mg daily, but irregular heart beats are still continuing. I had been wanting to take a drug holiday from Xtandi and Firmagon as I have been undetectable for 10 months now. Looks like I will be starting the holiday a little sooner than I thought. Would hate to stop the PC just to have the damn cancer drugs kill me with a heart attack ! Cant get into cardiologist for 2 weeks.

[timotur]

While you're waiting to see a Cardio, make sure you are well-hydrated and have ample electrolytes, especially potassium and calcium. I've had palpitations before and after being diagnosed with PCa, sort of like a fluttering heart that can't synch up, and drinking electrolytes and hydrating often helped the situation.

[joeguy in reply to timotur]

Thanks for the tip

[tango65 in reply to joeguy]

You could try to take some magnesium and see if it helps with the palpitations.

[tango65]

What does the electrocardiogram show? You could have Atrial Fibrillation (AF). AF requires treatment with anti arrhythmic drugs and also at our age with anti coagulation medication. Toprol is a beta blocker, it will reduce the heart rate and intensity of the heart contractions but it will not revert AF to sinus rhythm (normal rhythm).

[rococo]

Had irregular heartbeat for years . An Apple Watch which nudged me not to sit long periods and get up a move around every hour for a couple of minutes help immensely, Also take pharmaceutical fish oil and magnesium

[joeguy in reply to rococo]

I do sit for long hours as my work involves creating 3d computer models, so I get a lot of "screen time". I will try your advice and get up for a walk every hour.

[JuanVV]

Hi my husband has FA is taking Xtandi, before that he took Firmagon and became CR. His been taking Xtandi for at least 6 months and last month his PSA started finally to go down.

Xtandi and Firmagon a more 'heart' friendly I've understood that's why they chose it for my husband. But on the other hand he can't take the two together because theyd be too potent for him

[Magnus1964]

I have been on xtandi for 3 1/2 year with no heart problems yet.

[joeguy in reply to Magnus1964]

So far I have only been on it 10 months. I hate that it appears to be causing heart issues, because it has worked great.

[j-o-h-n]

I'm on lupron and casodex and I'm having issues with running out of breath...Shit happens.......

Good Luck, Good Health and Good Humor.

j-o-h-n Thursday 10/17/2019 5:10 PM DST

[joeguy in reply to j-o-h-n]

I have been noticing shortness of breath issues too........ starting to wonder if they are trying to kill me off with a heart attack before the cancer gets a chance to

[Kaliber in reply to joeguy]

Ah ha .... now you are starting to get it my brother. The oncologist can claim that they saved us with the treatments long enough for us to pass from natural causes Yayahahaha. Seems like it sometimes. Feels like it for sure. 👍

[monte1111 in reply to j-o-h-n]

Quit chasing the ex with a hatchet.

[j-o-h-n in reply to monte1111]

Gotta get a lighter hatchet....

Good Luck, Good Health and Good Humor.

j-o-h-n Thursday 10/17/2019 5:41 PM DST

[monte1111 in reply to j-o-h-n]

Lighter's better. "Here's j-o-h-n..........!"

[j-o-h-n in reply to monte1111]

If I could I'd put myself in an old ballroom photograph.....(forever, with no Pca and no ex-wife)....

Good Luck, Good Health and Good Humor.

j-o-h-n Thursday 10/17/2019 5:53 PM DST

[monte1111 in reply to j-o-h-n]

I'm sure we all would. Course the only ballroom I remember is the gym and the coach screaming "Dodge ball!" and us little guys huddling in a herd, turning white, (and Blackie turning gray), and the big guys, eyes red as fire snarling "gonna take you out." And they did, one by one. Kinda like Pca. Except there's no balls in Pca.

[j-o-h-n in reply to monte1111]

Now I know why you're allergic to balls............

Good Luck, Good Health and Good Humor.

j-o-h-n Thursday 10/17/2019 7:35 PM DST

[Kaliber in reply to j-o-h-n]

I used to think about ballrooms ......but don’t need ballroom anymore .... never took any pictures of it tho .... now it would be micro photography. 😁

[j-o-h-n in reply to Kaliber]

LOL they're called immies....

Good Luck, Good Health and Good Humor.

j-o-h-n Thursday 10/17/2019 8:06 PM DST

[Kaliber in reply to j-o-h-n]

Yayahahahaya you got that right.

[j-o-h-n]

You know the saying "six of one or half a dozen of the other"..... to use a medical term "we're fucked."

Good Luck, Good Health and Good Humor.

j-o-h-n Thursday 10/17/2019 5:22 PM DST

[Kaliber in reply to j-o-h-n]

Yep ... definitely not the life we ever thought we’d have in our so called golden years is it. Still life nevertheless... doesn’t come cheap tho ....

Screwed , blued, and tattooed....

[j-o-h-n in reply to Kaliber]

.....brewed, chewed and scata-oed.......

pyrite years...

Good Luck, Good Health and Good Humor.

j-o-h-n Thursday 10/17/2019 8:33 PM DST

[Hidden]

I take propafenone (rythmol) and 'toprol for a-fib. Xtandi could certainly be in my future. I wonder if I should insist on a-fib ablation now (I am almost 70) since future PC drugs or chemo could be a problem.

[x678was211]

Hi, I've been on XTANDI for month's now, I had a Stress Test last week to check on my one small blockage, which came back normal, except for a lot of PVC'S. I had a Halter Monitor done this week, and it show many, many, PAC'S which has me worried. I do drink some coffee though.

[joeguy]

I was on ADT drugs, including Xtandi for 3 years. While on ADT I experienced near constant PACs, and irregular beats. I was not told I should keep a close eye on bad cholesteral and trigycerides, and as a result they both got sky high before it was caught, This resulted in a 70% blockage of my LAD (the ol widow maker). After stopping all ADT drugs, the PACs and irregular beats have stopped, and the half dozen heart and BP drugs I am now on are keeping the blockage in check (it is in a poor location for a stint). I believe I was headed for a major heart attack had I not stopped the ADT drugs..... the question I am faced with now is what to do about the cancer?

[joeguy]

The urologist that did my RP was handeling ADT treatment at that point....... lipid profiles must have slipped his mind