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Caffeic acid phenethyl ester (CAPE) is an ingredient in bee propolis. See below for invitro and mice evidence for inhibition AR-V7 by CAPE
Human studies needed. Caffeic acid phenethyl ester suppresses the expression of androgen receptor variant 7 via inhibition of CDK1 and AKT Ying-Yu Kuo, Chieh Huo, Chia-Yang Li & Chih-Pin Chuu Cancer Gene Therapy (2024) doi: 10.1038/s41417-024-00753-z Abstract Androgen receptor (AR) splice variant
Human studies needed. Caffeic acid phenethyl ester suppresses the expression of androgen receptor variant 7 via inhibition of CDK1 and AKT Ying-Yu Kuo, Chieh Huo, Chia-Yang Li & Chih-Pin Chuu Cancer Gene Therapy (2024) doi: 10.1038/s41417-024-00753-z Abstract Androgen receptor (AR) splice variant
Graham49
in
Advanced Prostate Cancer
4 months ago
Iron infusion
Finally after many many months I found a sympathetic GP who referred me for an infusion on NHS ..a week later and I have an appt next week.Hopefully this will give me a much needed boost my ferritin is down to 18 and my TSA 11.4 ..any side effects on my atrophic gastritis known I would be glad to be
Finally after many many months I found a sympathetic GP who referred me for an infusion on NHS ..a week later and I have an appt next week.Hopefully this will give me a much needed boost my ferritin is down to 18 and my TSA 11.4 ..any side effects on my atrophic gastritis known I would be glad to be
davina70
in
Pernicious Anaemia Society
8 months ago
Celiac and CKD
I am wondering if anyone here has celiac? I have stage 4 kidney disease and celiac. I’m tired all the time to the point that I am not exercising like I should. I need procrit shots weekly just to keep my iron levels at the bare minimum. I’m not particularly interested in eating which may make the situation
I am wondering if anyone here has celiac? I have stage 4 kidney disease and celiac. I’m tired all the time to the point that I am not exercising like I should. I need procrit shots weekly just to keep my iron levels at the bare minimum. I’m not particularly interested in eating which may make the situation
ZenPDX
in
Kidney Dialysis
8 months ago
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Thyroid blood test results
Hi, I wonder if anyone could give me their opinion on these results:Iron - 106 Ferritin - 34 TSH - 0.378 Free T4 - 1.1 Free T3 - 3.08 I had been on 75mc. for many years and always felt okay but 4 weeks ago I had blood test for something and all the above were tested ,- subsequently I have now been put
Hi, I wonder if anyone could give me their opinion on these results:Iron - 106 Ferritin - 34 TSH - 0.378 Free T4 - 1.1 Free T3 - 3.08 I had been on 75mc. for many years and always felt okay but 4 weeks ago I had blood test for something and all the above were tested ,- subsequently I have now been put
Fisylvia
in
Thyroid UK
8 months ago
PA/b12 and ferratin
Hi, extremely confused here, I have been seeing a neurology specialist for cluster headaches, my last appointment I mentioned that I'm mixing my words up and my RLS (restless leg syndrome is getting worse).He asked if I'd had my bloods done and who was overseeing care.. I am PA, B12 deficient, folate
Hi, extremely confused here, I have been seeing a neurology specialist for cluster headaches, my last appointment I mentioned that I'm mixing my words up and my RLS (restless leg syndrome is getting worse).He asked if I'd had my bloods done and who was overseeing care.. I am PA, B12 deficient, folate
Mammymonster
in
Pernicious Anaemia Society
8 months ago
Busy, busy, busy!
Hello,, everyone! Just thought I'd pop in and say 'Hello!' as i've been really busy lately and not getting much chance to look in at the Forum. I sometimes get chance to read but not much time to respond - only to very few! I had COVID again a few weeks ago which has left me with an aversion to certain
Hello,, everyone! Just thought I'd pop in and say 'Hello!' as i've been really busy lately and not getting much chance to look in at the Forum. I sometimes get chance to read but not much time to respond - only to very few! I had COVID again a few weeks ago which has left me with an aversion to certain
MoyB
in
Lung Conditions Community Forum
8 months ago
dose increase?
Good morning I’m looking for a bit of advice about whether I should increase my Levothyroxine dose now, or wait a little while. I currently take 125/137.5 alternate days. I took a test after 6 weeks and have attached a picture of the results. I also had an iron panel done at the same time and, as per
Good morning I’m looking for a bit of advice about whether I should increase my Levothyroxine dose now, or wait a little while. I currently take 125/137.5 alternate days. I took a test after 6 weeks and have attached a picture of the results. I also had an iron panel done at the same time and, as per
BethBeezle
in
Thyroid UK
5 months ago
new blood tests
Hct is lower again to 37 and Hgb 11.5, iron panel still anemic. New Blood Test. Anion Gap. Normal range per lab. 6-22 My test result was 3 Anyone have any insight? thank you
Hct is lower again to 37 and Hgb 11.5, iron panel still anemic. New Blood Test. Anion Gap. Normal range per lab. 6-22 My test result was 3 Anyone have any insight? thank you
Pickleball11
in
MPN Voice
8 months ago
Low Iron
Hi everyone, Wondered if anyone has had experience with SVT and low iron? I’ve just found out that I have extremely low iron stores which explains a lot of my symptoms, including a fast heart rate and wondering whether anyone knows whether it could cause atrial tachycardia? I am really hoping once
Hi everyone, Wondered if anyone has had experience with SVT and low iron? I’ve just found out that I have extremely low iron stores which explains a lot of my symptoms, including a fast heart rate and wondering whether anyone knows whether it could cause atrial tachycardia? I am really hoping once
Cookieisland
in
British Heart Foundation
8 months ago
Just had a routine blood test from my GP
I know its possibly anemia... No wonder I have been even more tired etc.. Another repeat test in a month.. PV JAK2+ Pega, aspirin. Can they give me iron pills?
I know its possibly anemia... No wonder I have been even more tired etc.. Another repeat test in a month.. PV JAK2+ Pega, aspirin. Can they give me iron pills?
shiftzz
in
MPN Voice
8 months ago
Iron deficiency
After blood tests showed low ferritin and other values indicating iron deficient anaemia, the NHS did a fairly thorough job over 6 months with various tests and procedures to eliminate internal bleeds as a cause ( anticoagulant doesn't help!). Finally given the all clear and advised that iron supplementation
After blood tests showed low ferritin and other values indicating iron deficient anaemia, the NHS did a fairly thorough job over 6 months with various tests and procedures to eliminate internal bleeds as a cause ( anticoagulant doesn't help!). Finally given the all clear and advised that iron supplementation
50568789
in
Restless Legs Syndrome
5 months ago
Can low iron cause intolerance to thyroxine?
hello, Please see my prev post for my iron results. Since starting levo last year I have felt increasingly unwell on it. Mainly crippling joint and muscle pain which isn’t present when I’m not taking it, unfortunately the introduction of t3 at end of last year has only worsened this too. I can hardly
hello, Please see my prev post for my iron results. Since starting levo last year I have felt increasingly unwell on it. Mainly crippling joint and muscle pain which isn’t present when I’m not taking it, unfortunately the introduction of t3 at end of last year has only worsened this too. I can hardly
GreenTealSeal
in
Thyroid UK
5 months ago
T4 14.8 TSH 3.41
Hi, I’m new to the forum and blood tests in general so hopefully I will give relevant info. I’m 54 and have had fatigue for the past 6 months. I’ve always been fairly low energy but this is a different level. I am 10 years post menopause so it’s not that, and I’ve been on HRT a long time. My blood
Hi, I’m new to the forum and blood tests in general so hopefully I will give relevant info. I’m 54 and have had fatigue for the past 6 months. I’ve always been fairly low energy but this is a different level. I am 10 years post menopause so it’s not that, and I’ve been on HRT a long time. My blood
Lovicat
in
Thyroid UK
8 months ago
New to T3, advice please
Hello there, help please! Results listed below....I have always been symptomatic with Hashimoto's, diagnosed 2019. Was on just levo for years but after DIO2 testing and conversion rate of t4 to t3 being low I was started on a trial of T3 in march 2023. I always have blood testing between 8am and 9am.
Hello there, help please! Results listed below....I have always been symptomatic with Hashimoto's, diagnosed 2019. Was on just levo for years but after DIO2 testing and conversion rate of t4 to t3 being low I was started on a trial of T3 in march 2023. I always have blood testing between 8am and 9am.
Sammy333
in
Thyroid UK
8 months ago
Thyroid, Cortisol And Sodium Question
Hi All, Got my latest results and it's a bit messy. I got off NDT 1,5 grains and switched to 88 mcg of levo, my old levo I was on before. Prior to that, I was on 75/88 mcg, alternating. So I increased and now re-checked my bloods after 8 weeks. Btw, I'm well versed in everything recommended here
Hi All, Got my latest results and it's a bit messy. I got off NDT 1,5 grains and switched to 88 mcg of levo, my old levo I was on before. Prior to that, I was on 75/88 mcg, alternating. So I increased and now re-checked my bloods after 8 weeks. Btw, I'm well versed in everything recommended here
Juliet_22
in
Thyroid UK
8 months ago
Spotting from prednisolone or fibroid
Anyone had mid cycle spotting from oestrogen, prednisolone, iron tablets or fibroid?
Anyone had mid cycle spotting from oestrogen, prednisolone, iron tablets or fibroid?
Doodlebug23
in
Fertility Network UK
8 months ago
Pregabalin and Weight Gain
Hi Community Reaching out to your knowledge and lived experience once again. My RLS has been banished since taking Pregabalin- I take 150mg at night and usually get 5-6 hours of uninterrupted sleep. My referral to Leicester Sleep Clinic resulted in being told to take a multivitamin with iron for
Hi Community Reaching out to your knowledge and lived experience once again. My RLS has been banished since taking Pregabalin- I take 150mg at night and usually get 5-6 hours of uninterrupted sleep. My referral to Leicester Sleep Clinic resulted in being told to take a multivitamin with iron for
careerSquirrel
in
Restless Legs Syndrome
8 months ago
bad flare. How to reduce again?
Have GCA/PMR since 2020. Got down to 5 mgs but this last year huge stress moving house and city plus other stresses. Got terrible head pains back. Went on 25mgs for three days. Started dropping to 18 for three days and crashed again. Back to 25 last two days. Trying to get new doctors but ended up in
Have GCA/PMR since 2020. Got down to 5 mgs but this last year huge stress moving house and city plus other stresses. Got terrible head pains back. Went on 25mgs for three days. Started dropping to 18 for three days and crashed again. Back to 25 last two days. Trying to get new doctors but ended up in
CathyMeg
in
PMRGCAuk
8 months ago
blood count results?
Hi everyone! 😊 I was just wondering whether any of you wonderful intellectual people can read these blood results and maybe give me an insight to what they actually mean and if they are ok!? Iron is what I am most interested in… I am currently awaiting my yearly full vitamin panel blood test -
Hi everyone! 😊 I was just wondering whether any of you wonderful intellectual people can read these blood results and maybe give me an insight to what they actually mean and if they are ok!? Iron is what I am most interested in… I am currently awaiting my yearly full vitamin panel blood test -
ThyroidObsessed
in
Thyroid UK
8 months ago
Update 7.7
It has been a while since my last update. Overall, things are going well. I feel better than ever, other than my knees. Time for another hyaluronic acid injection to lubricate the knees. I am going to try Durolane this time. It is a single injection instead of a series of three. In other news
It has been a while since my last update. Overall, things are going well. I feel better than ever, other than my knees. Time for another hyaluronic acid injection to lubricate the knees. I am going to try Durolane this time. It is a single injection instead of a series of three. In other news
hunter5582
in
MPN Voice
8 months ago
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